
House vacation rentals in Saint Charles
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Top-rated house rentals in Saint Charles
Guests agree: these houses are highly rated for location, cleanliness, and more.

Historic Home on 4 Acres - Hot Tub, Pool, Tiki Bar
Our 1948 vacation home is on 4 acres & boasts 3 bedrooms, 3 full baths, 2 half baths, Bridal Suite (4th bedroom), 70s TV/Game Room, Tiki Bar, & Children's Playroom. Outside we have a pool (guaranteed to be open 5/26 - 9/5) & hot tub (year round). Located 15min away from Downtown DSM & a mile away from a grocery store/restaurants. Up to 2 dogs allowed for an additional fee. ***Events/photo shoots are allowed with written permission only and will be an added fee. No events larger than 25 total.***

The Hen House
The wonderfully remodeled home based on 55 acres overlooking mature trees and a large pond. The house has 3 bedrooms and 1 1/2 baths. Laundry is available to use as well. Kitchen is fully stocked for your cooking enjoyment and a gas grill is offered as well to use. This house is perfect for families, small groups, or business trips. Situated just 20 minutes from Des Moines airport, and 25 minutes from downtown Des Moines, you will be able to experience the quiet and beautiful scenery to enjoy.

Sassy, Fun, Adult Getaway! Gameroom!
Prof. designed w/feminine sass, this space has so many details to make you smile! From the cuss word coffee bar to the game room, to the aromatic scent bar to the adult themed card/board games, to the choice of soft cheetah print robes & luxurious throw blankets, no detail has been left out. Walking dist. to restaurants, bars, coffee shops, grocery stores, a spa/nail place & easy access to the bike trails & I235. 10 mins to downtown DSM or the nightlife of West Glen. Super safe, quiet nbrhood.

Effortless Landing near Airport & Downtown
Welcome to the Effortless Landing! Our super clean and comfy, Boho style retreat. Private keyless entry with off street parking. Enjoy a queen bed, additional pull out queen bed in couch, local coffee, & all the amenities like fiber wifi, TV, linens, full kitchen, & laundry. Add that to the wonderful surroundings of the city of Des Moines, in a quiet, centrally located neighborhood. Conveniently located 4 minutes from the Des Moines International Airport, & 7 minutes to Downtown Des Moines!

The Legacy Stone House
The most unique stay in Winterset! Legacy Stone House AirBnB is a historic residence located one mile east of Winterset, Iowa. Built in 1856 during the Settlement Era of Madison County, it is one of nearly 100 stone houses built during that time in the area. Officially named the William Anzi Nichols House, it is listed on the National Register of Historic Places. Convenient centralized location if visiting Madison County’s six covered bridges and two minutes from grocery, gas and dining.

The Country Oasis
Welcome to your perfect retreat—where comfort, style, and thoughtful details come together. The Country Oasis offers beautifully designed spaces to relax, recharge, and connect. This inviting vacation rental features 2 bedrooms and 2 bathrooms, making it perfect for your next getaway. With modern amenities and comforts such as a hot tub, fireplace, and various gathering spaces both indoors and out, The Country Oasis guarantees a memorable experience with friends and family.

Friendly Quarters
This charming location is a farmhouse style home built in 1914. Easily found on the main street through town, a one block walk in any given direction will put you at the center of the city. A grocery story, eating establishments, gift shops and community center are conveniently located in the downtown area. Friendly Quarters operates as a non-profit organization to support the missions and ministries of Earlham Friends (Quaker) Church located right next door.

Charming Home in Indianola
Discover comfort in our newly remodeled 3-bedroom home in the heart of Indianola, Iowa. This charming space boasts modern amenities and stylish decor, providing a cozy retreat for your stay. Enjoy a fully equipped kitchen, spacious living areas, and a modern bathroom. Perfect for families or groups, our home offers a blend of convenience and warmth. Explore nearby attractions or simply relax in our inviting space. Your home away from home awaits in Indianola!

Woodland Heights hist. district house on the hill.
Beautiful historic duplex house in the heart of woodland heights. Walking distance to downtown and next to Ingersoll avenue which is full of shops, bars, restaurants and more. Our place allows 2 parking spots on site with a side entrance to your upstairs Airbnb. The 800+ sq ft space includes a private kitchen, bathroom, bedroom, living room, and balcony with views of downtown. Picnic table and grassy area below balcony can be used on those nice Iowa days.

House in Creston
Relax with the whole family in this cute cozy house. The house sits on a large corner lot in a quiet neighborhood. 3 bedrooms, 1 king and 3 single beds. Even a toy room for the little ones. Relax in one of the 4 recliners and watch a movie on the big screen tv. Plenty of room to park the boats, electric for charging available and a fish cleaning table is available. Perfect place for your hunting or fishing trip. Pets welcome

Centrally Located Serene Wooded Retreat w/ Hot Tub
"...felt like we were tucked away in our own woods." - Ian 7 acres of space to roam. Spend time in the trees. Relax in the hot tub. Plenty of space to enjoy the duo of a serene getaway paired with enticing nightlife minutes away. Only minutes away from one of the most progressive dining and restaurant cultures in the Midwest. "Cutest house on a secluded lot close to downtown! Loved this rental so much!" - Marissa

Restored Victorian, Walk & Bike
Completely restored Victorian home that is walking and biking distance to the East Village, Civic Center, Wells Fargo, world-renowned skate park, and the Iowa Capitol! Bring your bike and enjoys the trails (and indoor bike parking). Walk to a concert at Wells Fargo or a show at the Civic Center. We are dedicated to making your stay simple and easy. This house is special to us, and we want to share it with you!
Popular amenities for Saint Charles house rentals
House rentals with a pool

New Arrival Peaceful Comfort Calm & Private

Urbandale Oasis

Fire Creek Homes

Huge Home, Gym, Game Room, Spa, BBQ, Near I-35

Big Groups/GameRM/Pool/Hot tub/Large backyard/Fire

Summer House DSM

House on Lake with in ground pool & camper hookup

Grimes Getaway with pool
Weekly house rentals

Victoria's House at Rose Farm

Cheerful 3 bedroom home in a quiet small town

Peaceful Setting & Modern Style

Drake neighborhood cottage

RARE Mid-Mod Home. Spacious inside-and-out.

The Cozy Cottage

White Oak Hillside Oasis

Cozy Historic Escape
Private house rentals

A farm get-a-way

The Draper-MCM Spacious Ranch minutes to it all

Charming abode

Cottage on Court: Historic Gem | 3 Blks to Square

Farm Escape | 12 Guest | Walk to Holliwell Bridge

The Beardsley House Norwalk Iowa

The Roost at Speckled Hen Farms.

Cute 1 bedroom and 1 bathroom!
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