
Apartment vacation rentals in Panama Canal
Find and book unique apartments on Airbnb
Top-rated apartment rentals in Panama Canal
Guests agree: these apartments are highly rated for location, cleanliness, and more.

In the heart of Casco, remodeled and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Colonial Luxury Apartment – Best Location in Old T
Welcome to our spacious colonial-style apartment, designed to comfortably host up to 8 guests in the heart of Casco Viejo. Located directly across from one of the most beautiful plazas in the historic district, you’ll be surrounded by renowned restaurants, cafés, and vibrant city life. The building features an elevator for your convenience and access to a rooftop terrace with a swimming pool, where you can enjoy stunning views of Casco Antiguo. Its prime location allows you to explore all the

Panoramic Casco Viejo Lookout in The Sands
exquisite apartment blends cozy comfort with sophisticated luxury. Every detail radiates elegance, from the plush, high-end furnishings to the warm, inviting ambiance. The open-concept living area is perfect for relaxing or entertaining, with breathtaking views of the UNESCO World Heritage Casco Viejo framing the horizon. The compact kitchen has modern appliances, sleek countertops, and all essentials. With Casco Viejo vistas, this stylish retreat is perfect for exploring culture and history.

Luxury Mid-Century Apartment In Casco Viejo
Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.

The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Canal Studio
Ground floor apartment, ideal for groups who love good taste, jungle landscapes and confort. Near the apartment there are paths to the Panama Canal, hills and jungle. Enjoy the elegance, nature and history of the Panama Canal with your family and friends in a jungle environment, quiet and very confortable. Ground floor apartment, ideal for groups who love good taste, jungle landscapes and comfort. Near the apartment there are paths to the Panama Canal, hills and jungle.

Walk to Everything | Luxury Stay in Casco Viej
Wake up overlooking one of the last historic bastions of Casco Viejo, sip your morning cofee on a private balcony, and step directly into Panama City most vibrant and wakable neighboorhood. Surrounded by colonial architecture, charming plazas, and a vibrant culinary scene, this space invites you to experience Panama with style and tranquility. Ideal for those seeking an exclusive, walkable, and characterful environment in one of the city's most iconic areas.

Gorgeous Flat in the best location in Casco Viejo
This cute and stylish studio is perfectly located in the heart of Casco Viejo, Panama City’s most charming historic district. Recently renovated, it combines modern comfort with classic charm inside a beautiful colonial building—just steps from top restaurants, bars, monuments, and attractions. The space includes a comfortable sofa bed, making it ideal for a couple or a small family looking to enjoy the vibrant atmosphere of Casco right outside their door.

Private parking & rooftop | Studio Casco Center
This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

The best view of the Old Town
Welcome to this charming accommodation located in the heart of Casco Viejo, on the third floor facing one of the most iconic squares in Panama, Plaza Catedral! Thanks to its privileged location, you will enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you will have at your disposal a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.

Most Beautiful Loft in the Heart of Casco Viejo
Discover Casco Viejo from this beautiful loft, perfectly located. Casco Viejo, UNESCO World Heritage Site, known for its colonial buildings, and iconic streets. This vibrant neighborhood offers many restaurants, coffee places, museums, and an exciting night life. Just steps from Fonda Lo Que Hay, ranked among Latin America's Top 50 culinary destinations. Close to MYKA Greek Yogurt and the iconic La Compañía Hotel.

Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.
Popular amenities for Panama Canal apartment rentals
Weekly apartment rentals

Peaceful Stay in the Heart of Casco

Spectacular Bay View • 1BR • Pool/Gym and +

Apartment Casco Antiguo Panamá

Old Town & Ocean View

811 San Felipe

Ocean View Suite Coastal Strip

Villas La Fontana Spacious ApartaSuite - Pool 104

Lovely & Cozy central apartment in Casco Viejo
Private apartment rentals

Cozy Apartment in the Heart of Casco Viejo

Ocean View, Panama City

Apartment with home warmth

Unique Luxury 3-story Loft at the Yoo

A warm and cozy flat in Casco Viejo

Luxury apt in Panama City 2 Rooms 3 Baths

Lujoso apartamento en el corazón de Panamá

Poin Avenida Balboa, Panama City
Apartment rentals with a hot tub

Ocean View Apt in Panama, Yoo&Arts

New Flat with Ocean + City Views

Tropical Paradise at Playa Bonita

Skyline Views | Designer Suite | Zipline Onsite

Apartment in Obarrio with Rooftop | Pool and View

PH The Gray | Balcony Views · Pool · Gym

Vive la Experiencia Wanders And Yoo en Panamá

Premium APT | Downtown | Design, Comfort, Parking
Destinations to explore
- Rentals with a patio Panama Canal
- Rentals with outdoor seating Panama Canal
- Townhouse rentals Panama Canal
- Rentals with an EV charger Panama Canal
- Rentals with breakfast Panama Canal
- Loft rentals Panama Canal
- Family-friendly rentals Panama Canal
- Hostel rentals Panama Canal
- Guesthouse rentals Panama Canal
- Condo rentals Panama Canal
- Serviced apartment rentals Panama Canal
- Rentals with a sauna Panama Canal
- Waterfront rentals Panama Canal
- Bed and breakfasts Panama Canal
- Hotel rooms Panama Canal
- Rentals with pools Panama Canal
- Rentals with an accessible height bed Panama Canal
- Private suite rentals Panama Canal
- Rentals with a home theater Panama Canal
- Pet-friendly rentals Panama Canal
- Boutique hotels Panama Canal
- Rentals with a washer and dryer Panama Canal
- Rentals with beach access Panama Canal
- Rentals with a fire pit Panama Canal
- Beachfront rentals Panama Canal
- Rentals with a kayak Panama Canal
- Rentals with lake access Panama Canal
- House rentals Panama Canal
- Fitness-friendly rentals Panama Canal
- Rentals with a hot tub Panama Canal
- Smoking-friendly rentals Panama Canal
- Apartment rentals Panama
- Things to do Panama Canal
- Sightseeing Panama Canal
- Sports activities Panama Canal
- Tours Panama Canal
- Art and culture Panama Canal
- Food and drink Panama Canal
- Nature and outdoors Panama Canal
- Things to do Panama
- Food and drink Panama
- Art and culture Panama
- Nature and outdoors Panama
- Sightseeing Panama
- Tours Panama





