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Apartment vacation rentals in Panama Canal

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Top-rated apartment rentals in Panama Canal

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Guest favorite
Apartment in San Felipe
4.96 out of 5 average rating, 255 reviews

In the heart of Casco, remodeled and with parking

Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Top guest favorite
A well-lit dining area features a large wooden table surrounded by upholstered chairs. Exposed wooden beams contrast with the smooth, light-colored walls, creating an open and airy feel. Two sets of shuttered windows allow natural light to enhance the space.
Apartment in San Felipe
4.89 out of 5 average rating, 141 reviews

Colonial Luxury Apartment – Best Location in Old T

Welcome to our spacious colonial-style apartment, designed to comfortably host up to 8 guests in the heart of Casco Viejo. Located directly across from one of the most beautiful plazas in the historic district, you’ll be surrounded by renowned restaurants, cafés, and vibrant city life. The building features an elevator for your convenience and access to a rooftop terrace with a swimming pool, where you can enjoy stunning views of Casco Antiguo. Its prime location allows you to explore all the

Top guest favorite
Apartment in Panama City
4.95 out of 5 average rating, 61 reviews

Panoramic Casco Viejo Lookout in The Sands

exquisite apartment blends cozy comfort with sophisticated luxury. Every detail radiates elegance, from the plush, high-end furnishings to the warm, inviting ambiance. The open-concept living area is perfect for relaxing or entertaining, with breathtaking views of the UNESCO World Heritage Casco Viejo framing the horizon. The compact kitchen has modern appliances, sleek countertops, and all essentials. With Casco Viejo vistas, this stylish retreat is perfect for exploring culture and history.

Guest favorite
A spacious living room features a comfortable brown sofa and an armchair beside a decorative coffee table. Natural light enters through large glass doors draped with sheer curtains, illuminating the warm wood floors and elegant decor.
Apartment in San Felipe
4.96 out of 5 average rating, 113 reviews

Luxury Mid-Century Apartment In Casco Viejo

Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.

Top guest favorite
Apartment in San Felipe
4.98 out of 5 average rating, 124 reviews

The View of Casco: Designer Loft with best Balcony

Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! ​Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. ​You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Guest favorite
A cozy living area is observed with a round dining table surrounded by four upholstered chairs. A sofa and armchair face a TV unit, while large windows provide natural light and views of the surrounding greenery.
Apartment in Panama City
4.96 out of 5 average rating, 46 reviews

Canal Studio

Ground floor apartment, ideal for groups who love good taste, jungle landscapes and confort. Near the apartment there are paths to the Panama Canal, hills and jungle. Enjoy the elegance, nature and history of the Panama Canal with your family and friends in a jungle environment, quiet and very confortable. Ground floor apartment, ideal for groups who love good taste, jungle landscapes and comfort. Near the apartment there are paths to the Panama Canal, hills and jungle.

Top guest favorite
Apartment in San Felipe
4.97 out of 5 average rating, 33 reviews

Walk to Everything | Luxury Stay in Casco Viej

Wake up overlooking one of the last historic bastions of Casco Viejo, sip your morning cofee on a private balcony, and step directly into Panama City most vibrant and wakable neighboorhood. Surrounded by colonial architecture, charming plazas, and a vibrant culinary scene, this space invites you to experience Panama with style and tranquility. Ideal for those seeking an exclusive, walkable, and characterful environment in one of the city's most iconic areas.

Top guest favorite
Apartment in San Felipe
4.94 out of 5 average rating, 67 reviews

Gorgeous Flat in the best location in Casco Viejo

This cute and stylish studio is perfectly located in the heart of Casco Viejo, Panama City’s most charming historic district. Recently renovated, it combines modern comfort with classic charm inside a beautiful colonial building—just steps from top restaurants, bars, monuments, and attractions. The space includes a comfortable sofa bed, making it ideal for a couple or a small family looking to enjoy the vibrant atmosphere of Casco right outside their door.

Top guest favorite
Apartment in San Felipe
5.0 out of 5 average rating, 35 reviews

Private parking & rooftop | Studio Casco Center

This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Guest favorite
A cozy sitting area is highlighted by a large window offering views of the vibrant plaza and cathedral. Two comfortable armchairs are positioned beside a small coffee table on a textured rug. Natural light fills the space, enhancing the warm tones of the wooden floor.
Apartment in San Felipe
4.91 out of 5 average rating, 121 reviews

The best view of the Old Town

Welcome to this charming accommodation located in the heart of Casco Viejo, on the third floor facing one of the most iconic squares in Panama, Plaza Catedral! Thanks to its privileged location, you will enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you will have at your disposal a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.

Top guest favorite
Apartment in San Felipe
5.0 out of 5 average rating, 28 reviews

Most Beautiful Loft in the Heart of Casco Viejo

Discover Casco Viejo from this beautiful loft, perfectly located. Casco Viejo, UNESCO World Heritage Site, known for its colonial buildings, and iconic streets. This vibrant neighborhood offers many restaurants, coffee places, museums, and an exciting night life. Just steps from Fonda Lo Que Hay, ranked among Latin America's Top 50 culinary destinations. Close to MYKA Greek Yogurt and the iconic La Compañía Hotel.

Guest favorite
Apartment in San Francisco
4.98 out of 5 average rating, 156 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Popular amenities for Panama Canal apartment rentals