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Apartment vacation rentals in Panama Canal

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Top-rated apartment rentals in Panama Canal

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Apartment in Panamá

4.86 out of 5 average rating, 267 reviews

Casco Viejo 360° View Old Tower Penthouse

Located in one of the oldest buildings in Panama and set over 3 stories with unrivaled panoramic views over the historical Casco Viejo, the skyline of Panama City and views of the causeway, our gorgeous penthouse is the ideal space to take in the local sights, sounds, art, culture, socialize with your friends and family, or simply relax in a cozy love nest! Top speed wifi, excellent location, and fully equipped with all the home comforts, the penthouse is the perfect spot to explore Panama.

Sep 25 – Oct 2

G$78,299 GYD per night

Apartment in Panamá

4.9 out of 5 average rating, 360 reviews

Chic Studio in Casco Antiguo - View to Main Plaza

Located in trendy Casco Antiguo, this studio apartment is walking distance of restaurants, cafes, supermarkets, pharmacies and the overall life of Casco. The building has recently been renovated and has a beautiful view of Plaza Catedral. Note: As seen on previous comments, there used to be a bar club in the rooftop and at the bottom of the building. Good news, there are no more bars in the building and the studio has soundproof doors as Casco is an area with the best nightlife in Panama.

Aug 20 – 27

G$23,530 GYD per night

Apartment in Panamá

5.0 out of 5 average rating, 28 reviews

Amazing experience in Casco Viejo with ocean views

Disfruta la cultura panameña desde el centro de Casco Viejo, donde conocerás la arquitectura colonial, podrás visitar los mejores restaurantes, sitios nocturnos y rooftops característicos de la zona. Apartamento tranquilo y confortable. Cuenta con una cama queen, 1.5 baños, armario, aire acondicionado, cocina equipada, comedor, sala, acceso a WiFi de 500 mbps, espacio de trabajo, balcón y comedor al aire libre. ¡Te ofrecemos todo lo que necesitas para vivir la mejor experiencia local!

Mar 18 – 25

G$23,185 GYD per night

Apartment in Panamá

4.96 out of 5 average rating, 218 reviews

Mola Studio | By Paradox

If you're looking to get sumerged into real Panama and live among the real locals. This is the right place to be. We must clarify that we are NOT located in Casco Viejo specifically. We are located on the historic Central Avenue better known as La Peatonal, a few blocks from Casco Viejo. It has all the necessary amenities like a full kitchen, hot shower and A/C. Close to pharmacies, supermarkets, Subway/Bus stations, banks/ATMs, private parking lots, and a wide range of restaurants.

Dec 2 – 9

G$11,361 GYD per night

Apartment in Panamá

4.98 out of 5 average rating, 107 reviews

Ocre Studio | By Paradox

If you're looking to get sumerged into real Panama and live among the real locals. This is the right place to be. We must clarify that we are NOT located in Casco Viejo specifically. We are located on the historic Central Avenue better known as La Peatonal, a few blocks from Casco Viejo. It has all the necessary amenities like a full kitchen, hot shower and A/C. Close to pharmacies, supermarkets, Subway/Bus stations, banks/ATMs, private parking lots, and a wide range of restaurants.

Sep 25 – Oct 2

G$11,361 GYD per night

Apartment in Panamá

4.97 out of 5 average rating, 33 reviews

Entire home with parking

Bienvenidos to our entire modern and central one-bedroom apartment! Stylishly decorated and equipped with everything you need for your stay, this space is perfect for those looking for comfort and convenience in the city center. With a king bed, a living room with a sofa and a TV, and a full kitchen, you'll feel right at home. In addition, the location in the center and is close to public transportation. Make this apartment your home during your city visit!

Dec 8 – 15

G$13,742 GYD per night

Apartment in Panamá

4.82 out of 5 average rating, 33 reviews

Beautiful apartment in Casco Viejo

Located in the heart of Casco Viejo. It has a button service that takes your luggage to the apartment, it has a rooftop where you can watch the sunset with the view of the city, the canal and the majestic sea. The building's ground floor is home to La Cuadra Market where there are a variety of renowned restaurants with different styles of food, as well as a bar. Close to everything, you can walk around everything and enjoy every place it offers you.

Apr 17 – 24

G$18,359 GYD per night

Apartment in Panamá

4.85 out of 5 average rating, 230 reviews

Pool and rooftop with Two Bedrooms and Kitchen A8

Unique architecture in Casco Viejo, entirely renovated very recently. You have a pool, a rooftop, and your completely private and brand new room. Double bed, designer furniture, tv with Netflix, air conditioning, sheets and towels, shampoo, soap, etc. The building with more history of Casco Viejo, given its name after the first president of the republic in 1903, Tomas Arias, who lived here. The accommodation consists of: - Room No.

Aug 13 – 20

G$32,372 GYD per night

Apartment in Panama City

4.97 out of 5 average rating, 39 reviews

Stunning views from the clouds!

*** Internet 500Mbps Wifi Pro *** *** Netflix, Prime Video, HBOmax, Youtube Premium *** Cozy and spectacular apartment all dressed in white. You will enjoy daily incredible views of the symbols of Panama: the islands, Causeway, Old Town, Canal, Metropolitan park. In this bubble over the bay, you will feel like in the clouds! Place of inspiration and relaxation, strategically located, you will have the whole city at your feet!

Aug 15 – 22

G$34,282 GYD per night

Apartment in Panamá

4.92 out of 5 average rating, 38 reviews

Beautiful apartment in Casco Viejo ST. George D

Welcome to our spacious and charming apartment in Casco Viejo. Located in a vibrant, historic neighborhood. You will love the warm atmosphere created by the lime and singing walls, in perfect harmony with our modern and elegant decor. The space is large and comfortable, ideal for relaxing after a day exploring the city. As a host, I am available 24/7 to answer your questions and make sure you make the most of your stay.

Sep 3 – 10

G$30,129 GYD per night

Apartment in Panamá

5.0 out of 5 average rating, 19 reviews

Luxury Apartment Panama Centro, Banking Area

We have a strategic location right on Panama's main thoroughfare (Calle 50) Bella Vista, you are located in the heart of the banking area. If you are coming for work or vacation, this is the place, you will find all kinds of restaurants nearby, shops, shopping center, you will have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

Jan 9 – 16

G$12,001 GYD per night

Apartment in Panamá

5.0 out of 5 average rating, 20 reviews

Tropicool Loft w/rooftop steps from Casco

This loft is located at the entrance of Casco Viejo where you’re steps from the fish market and all the cool cafés, rooftop bars, and trendy restaurants that make up the neighborhood. Fully equipped kitchen, washer/dryer, 1.5 bath, bedroom on 2nd floor, 2 balconies + communal rooftop, projector w/Netflix, fiber optic internet, and great AC to keep the place cool.

Sep 28 – Oct 5

G$21,216 GYD per night

Vacation rentals for every style

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Spaces that are more than just a place to sleep

Popular amenities for Panama Canal apartment rentals

Free parking on premises

Air conditioning

Weekly apartment rentals

Apartment in Panama City

5.0 out of 5 average rating, 21 reviews

Luxury Mid-Century Apartment In Casco Viejo

Jul 29 – Aug 5

G$28,742 GYD per night

Apartment in Panamá

5.0 out of 5 average rating, 18 reviews

Albrook Private Apt near Airport

Apr 9 – 16

G$18,001 GYD per night

Apartment in Panamá

5.0 out of 5 average rating, 39 reviews

Full apartment in Panama

Mar 28 – Apr 4

G$16,199 GYD per night

Apartment in Panamá

4.98 out of 5 average rating, 82 reviews

Cozy 2 Bedroom w/ Splash Pool

Dec 14 – 21

G$24,778 GYD per night

Apartment in Panamá

4.91 out of 5 average rating, 58 reviews

Best location - Spacious and Fancy Apt

Oct 24 – 31

G$30,108 GYD per night

Apartment in Panamá

4.9 out of 5 average rating, 20 reviews

Apartment in the Causeway Amador

Oct 29 – Nov 5

G$49,587 GYD per night

Apartment in Panamá

5.0 out of 5 average rating, 19 reviews

Top Floor Condo 6 bedroom with amazing views

Aug 13 – 20

G$111,438 GYD per night

Apartment in Panamá

4.94 out of 5 average rating, 18 reviews

King Bed Suite / 280 Degree View / 500mbs WiFi

Mar 31 – Apr 7

G$53,562 GYD per night

Private apartment rentals

Apartment in Panamá

4.97 out of 5 average rating, 63 reviews

Superb Apartment In The Center Of Panama City

Jul 25 – Aug 1

G$16,157 GYD per night

Apartment in Panamá

4.96 out of 5 average rating, 68 reviews

Beautiful boutique apartment in Avenida Balboa

Jun 7 – 14

G$24,592 GYD per night

Apartment in Panamá

4.9 out of 5 average rating, 72 reviews

Cozy apartment near Casco Viejo

Sep 29 – Oct 6

G$15,562 GYD per night

Apartment in Panamá

5.0 out of 5 average rating, 3 reviews

Condo for 2 people, Downtown

Oct 29 – Nov 5

G$14,783 GYD per night

Apartment in Panamá

5.0 out of 5 average rating, 15 reviews

Spacious Executive High-Floor Quiet Apt w/Balcony

Jun 18 – 25

G$20,389 GYD per night

Apartment in Panama City

5.0 out of 5 average rating, 15 reviews

BEST VIEW in Old Town, Panama (Casco Viejo)

Dec 4 – 11

G$22,474 GYD per night

Apartment in Panamá

5.0 out of 5 average rating, 12 reviews

Apartmentamento in Panama

Mar 17 – 24

G$18,342 GYD per night

Apartment in Maria Chiquita

4.96 out of 5 average rating, 57 reviews

Spacious 4Br Beachside Getaway at Playa Escondida

Aug 21 – 28

G$110,550 GYD per night

Apartment rentals with a hot tub

Apartment in Panamá

4.84 out of 5 average rating, 114 reviews

Your apartment in Panama! with a nice view of the city

Jun 10 – 17

G$11,766 GYD per night

Apartment in Maria Chiquita

4.98 out of 5 average rating, 51 reviews

Marina House at Playa Escondida Resort

Jul 12 – 19

G$55,523 GYD per night

Apartment in Panamá

5.0 out of 5 average rating, 12 reviews

Oceanview Apt Near Panama City w/ King Bed & More

May 15 – 22

G$52,206 GYD per night

Apartment in María Chiquita

4.94 out of 5 average rating, 64 reviews

Playa Escondida Resort & Marina

Oct 15 – 22

G$85,281 GYD per night

Apartment in Maria Chiquita

5.0 out of 5 average rating, 19 reviews

Beachfront Views Great Location

Jun 19 – 26

G$67,911 GYD per night

Apartment in Maria Chiquita

4.88 out of 5 average rating, 86 reviews

Beachfront Views / Ocean view in Playa Escondida

Sep 27 – Oct 4

G$72,002 GYD per night

Apartment in Colón

4.86 out of 5 average rating, 79 reviews

Hidden beach, a gem in the Panamanian Caribbean

Jun 4 – 11

G$53,849 GYD per night

Apartment in Panamá

4.83 out of 5 average rating, 24 reviews

Hotel with free breakfast Gym Pool Jacuzzi

Dec 2 – 9

G$20,494 GYD per night

Destinations to explore