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House vacation rentals in Panama Canal

Find and book unique houses on Airbnb

Top-rated house rentals in Panama Canal

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite
An open-concept loft is showcased with a high, sloped ceiling and large windows that invite natural light. Comfortable seating is arranged around a glass table, while a dining area and a cozy sleeping space can be seen in the background. Nature views are visible through the windows.
Home in Santa Rita Arriba
4.94 out of 5 average rating, 18 reviews

The Bird's Nest in the Clouds

Escape to the Clouds: A Nature Lover’s Retreat. Welcome to The Bird's Nest, a serene loft in Santa Rita Arriba, Colón, 50 minutes from the city. Perched in the mountains, this open-concept space offers breathtaking views, fresh breezes, and the sounds of nature - rain and birds. Sleep with doors open, no AC. Perfect for nature lovers, not for those needing silence or climate control. Pool with breathtaking view, wifi and modern comforts included. PLEASE READ ENTIRE DESCRIPTION BEFORE BOOKING.

Top guest favorite
The image showcases the exterior of a two-story house, framed by lush greenery. Sunlight filters through trees, highlighting the white façade and green shutters. A covered area is visible at the front, along with a gated fence that adds security to the property.
Home in Panamá
4.9 out of 5 average rating, 110 reviews

3BR Home in Ancon Hill - Urban Oasis

Discover our home at Ancon Hill in Panama City, steps from Supreme Court. The hill offers scenic hiking trails to the top with city views, lush greenery, and wildlife. 5 min to Albrook Mall. 10 min to Casco Viejo (UNESCO site, restaurants, museums, nightlife), Amador Causeway, Cinta Costera, Metropolitan Park, Panama Convention Center, and Albrook Airport. 20 min to Panama Canal Miraflores Locks and Veracruz beach (across Bridge of Americas, gateway to countryside). 35 min to Tocumen Airport.

Guest favorite
A vibrant water park is illustrated, featuring an array of colorful slides and a large structure with water cascading from the top. Bright green and yellow slides are visible, alongside purple and blue ones, all surrounded by palm trees against a clear blue sky.
Home in Panamá Oeste
4.94 out of 5 average rating, 108 reviews

AX8 beach house near the city!

Cozy and fully furnished home with hammocks to relax and a BBQ grill, perfect for sharing special moments. Enjoy access to a pool with waterslides, 🚣‍♂️ kayak-friendly lagoon, and ⚓ pirate ship for kids. Plus, play on the beach volleyball and sand soccer courts or stay active at the outdoor gym. 🎟️ Complimentary club access from Tuesday to Sunday, 8 a.m. - 6 p.m. (Closed on Mondays). Open daily on holidays. ✨ A space designed for you. Book now and enjoy the experience! ✨

Guest favorite
Home in Colón
4.86 out of 5 average rating, 49 reviews

Family style living and close to the Panama Canal

As of OCT 2022 we double the Space for this house, see new photos. This house is located on reverted American areas transferred back to Panama, called Arco Iris, there’s plenty of space outside, the backyard can fit your family barbeque, the inside consist of an modern combination living room + kitchen, large bathroom and 2 bedrooms with closets, the place is air conditioned with large ceiling fans in each room and private parking. Pickup from the airport available for a fee

Superhost
A tranquil dipping pool is framed by lush greenery, featuring white loungers and a large umbrella for shade. The pool area exudes a serene vibe with vibrant bougainvillea in the background, enhancing the inviting outdoor space.
Home in Taboga Island
4.94 out of 5 average rating, 220 reviews

Casa Rosie - Dream Home on Tabogá Island

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Superhost
A lush green lawn showcases well-maintained grass, framed by tropical plants with vibrant yellow leaves. In the background, a spacious outdoor area is visible, featuring a covered seating area. Hammocks are gently swaying, inviting relaxation amidst the natural surroundings.
Home in Panamá
4.82 out of 5 average rating, 55 reviews

Wonderful nature

Enjoy a family retreat in the heart of nature, where tranquility envelops you. This cozy accommodation, surrounded by a beautiful garden in the Metropolitan Natural Park, offers you a unique escape just 3 minutes from Albrook Mall and 5 minutes from downtown. Wake up to birdsong and a visit from the ñeques (agoutis), while relaxing in an exclusive and lively atmosphere. The perfect getaway to disconnect and enjoy nature with all the amenities!

Top guest favorite
A spacious living and dining area is depicted, featuring a blue sectional sofa with yellow accent pillows. A glass dining table with yellow placemats and black chairs is shown. Natural light enters through windows, revealing a glimpse of greenery outside.
Home in Panama City
4.83 out of 5 average rating, 126 reviews

Spacious Panama House in the 'heart of the city'

You couldn't ask for a better place to stay while you visit Panama. This location is perfect, while other properties might advertise similar amenities; not one of them can boast a combination of space and amazing location quite like this one. This is very private & secure property in a fantastic, & very safe area right in the heart of the city & close to everything! An oasis in the middle of the city with AC IN EVERY ROOM AND DININING ROOM.

Top guest favorite
A private pool area is framed by lush tropical plants and trees, with lounge chairs situated nearby. The pool’s clear blue water reflects the surrounding greenery and the structure in the background, which includes a covered patio for relaxation.
Home in Las Colinas de Caceres de Arraijan
4.98 out of 5 average rating, 232 reviews

Tropical Haven with Pickleball/Yoga Platform

Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Guest favorite
Home in Panamá
5 out of 5 average rating, 14 reviews

3BR Mountain Retreat | Starlink WiFi | Cerro Azul

Escape to the cool mountain weather of Cerro Azul and enjoy a modern home surrounded by nature. Perfect for families, groups of friends, and remote work, with high-speed Starlink internet for seamless video calls and streaming. Relax on the spacious balcony, enjoy the BBQ gazebo, and unwind from city life while surrounded by fresh air, peaceful surroundings, and natural views. Have questions? Send us a message today!

Guest favorite
A charming facade displays three balcony areas adorned with greenery, enhancing the welcoming appearance of the building. The entrance features decorative signage alongside floral accents, while the muted color palette and architectural details of the windows contribute to the overall harmonious design.
Home in Panamá
4.88 out of 5 average rating, 33 reviews

Comfortable and luxurious apartment

Enjoy a stylish experience in our accommodation in the Old Town, take advantage of the location close to art galleries, restaurants, crafts, etc. Our house has three bedrooms each with a balcony, bathroom and closet, with a nice contemporary equipped kitchen; a large living and dining room, work area. You have a total area of 326 m² The whole house is surrounded by balconies where you can enjoy panoramic views.

Guest favorite
A private rooftop terrace offers expansive views of the ocean and skyline. Comfortable seating arrangements include a coffee table and lounge chairs beneath a shaded umbrella. Decorative plants enhance the outdoor space, while string lights provide a warm ambiance during evenings.
Home in Panamá
4.92 out of 5 average rating, 169 reviews

Exceptional three-story building with sea view

This stunning three-story property, located in Casco Viejo, boasts a terrace with a sea view. Designed with a focus on elegance and relaxation, the house features spacious and well-lit interiors adorned with modern and high-quality decor. The strategic location of the house allows for breathtaking views from the terrace, offering a unique blend of luxury and relaxation in a historic and picturesque setting.

Guest favorite
Home in Panamá
4.94 out of 5 average rating, 424 reviews

Private Studio 10 Min from the Airport!

Apartamento Entero 10 MINUTES FROM the Airport! The apartment is fully furnished, including appliances and kitchenware, toiletries, a living/dining room, a work table, and more. Only a few minutes' walk to the SAN ANTONIO METRO Station and METROMALL. We offer tours to San Blas - Tours to Monkey Island and the Panama Canal to help you make the most of your trip. Our home is Your home in Panama 🇵🇦

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