Vacation rentals in Panama Canal

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Top-rated vacation rentals in Panama Canal

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost

A cozy living area features a comfortable blue sofa against an original brick wall, complemented by a round mirror. A small kitchen area with white cabinetry and modern appliances is visible. A decorative coffee table and elegant chairs complete the inviting space.

Apartment in Panamá

4.81 out of 5 average rating, 144 reviews

The Penthouse Annex

Inspired by Panama's rich history with France and located in one of the oldest watch towers in Panama, this chic apartment combines original features of this historically important building with the elegance and style of Europe. Perfectly situated to indulge in the restaurants, cafes, museums and boutique stores of Casco Viejo, and equipped with everything you expect from a home-from-home base, the annex is the perfect combination of comfort and style for couples and small groups of friends.

Top guest favorite

A communal rooftop space is revealed, showcasing several white-accented chairs and small tables arranged amidst potted plants. The backdrop features a panoramic view of the Panama City skyline against a clear blue sky.

Apartment in Panamá

5 out of 5 average rating, 48 reviews

Tropicool Loft w/rooftop steps from Casco

This historic 1941 loft is located at the entrance of Casco Viejo where you’re steps from the fish market and all the cool cafés, rooftop bars, and trendy restaurants that make up the neighborhood. Fully equipped kitchen, washer/dryer combo, 1.5 bath, bedroom on 2nd floor, 2 balconies + communal rooftop, projector w/Netflix, fiber optic internet, and great AC to keep the place cool. You’re also directly in front of the Cinta Costera park for running, biking, and free tennis courts.

Guest favorite

A modern living area features a large wave mural that enhances the space's vibrant decor. Comfortable seating arrangements include a sleek white sofa and a pair of stylish armchairs. A glass coffee table is centered among the furnishings, with tastefully arranged decorative accents.

Apartment in Panamá

4.93 out of 5 average rating, 252 reviews

Modern apt ocean view in heart of Panamá yoo tower

Este lugar tiene una ubicación estratégica: ¡será muy fácil planear tu visita! Ph Yoo and Arts, ubicado en Av. Balboa, súper céntrico Esta hermosa y moderna propiedad cuenta con un estilo único y una vista al mar increíble, piso alto, 2 habitaciones, 2.5 baños completos, Lavanderia, amplia terraza, luces dimeables en todo el espacio, sala comedor, sala de películas, espacio de trabajo, 3 smart tvs, 3 aires acondicionados céntrales, cocina full equipada, cristalería moderna.

Superhost

A modern living area is presented, featuring a comfortable sofa with decorative cushions. A large television is mounted above a sleek media console. Floor-to-ceiling glass doors open to a balcony, showcasing an expansive view of the ocean. Bright natural light illuminates the space.

Apartment in Panamá

5 out of 5 average rating, 5 reviews

Yoo Panama - Luxurious and comfortable

Modern, luxurious and unique apartment, which has a spectacular location in one of the most luxurious buildings in Panama City, with all the amenities of a hotel, near supermarkets, pharmacies, restaurants, shopping centers and more The undoubted character, luxury and comfort that this apartment exudes makes it really difficult to leave at the end of your stay. With its enviable ocean view, guests can disconnect, relax and savor this magical destination

Guest favorite

A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.

Apartment in Panamá

4.98 out of 5 average rating, 141 reviews

Escape to the Heart of Casco with a Private Balcony

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Guest favorite

A rooftop area is presented, featuring a large swimming pool surrounded by lounge chairs. Two distinct sections for relaxation are visible, with white cabanas and minimalist furniture contrasting against sleek, modern surfaces. City buildings create a backdrop, enhancing the urban atmosphere.

Apartment in Panamá

4.95 out of 5 average rating, 40 reviews

Spacious oceanfront apartment

Discover an exceptional apartment in the iconic Yoo Art Panama building, located in the best waterfront area. This luxurious space combines modern design and functionality, offering panoramic views that will leave you breathless. The entire building is a work of art and has the best works of the great designer Philippe Starck. Enjoy a wide range of top-notch amenities facing the sea, in the financial and tourist power that is Panama 🇵🇦

Top guest favorite

A welcoming living area features modern furnishings and vibrant artwork. A round wooden coffee table is accompanied by a cozy sofa and armchairs. Natural light pours in from large glass doors leading to a balcony, while a plant adds a touch of greenery.

Apartment in Panamá

4.95 out of 5 average rating, 116 reviews

Luxury apartment in Panama, ocean view

Located in San Francisco, one of Panama's exclusive areas par excellence, where gastronomy, history, modernity, and entertainment magically combine. Wonderful location near must-see destinations, gym, swimming pool, co-working, pet spa, and terrace. Parking is charged. Modern and functional, this apartment features a queen-size bed, fully-equipped kitchen, Wi-Fi, TV, a spectacular balcony with ocean views, laundry center, and sofa bed.

Guest favorite

An infinity pool stretches towards the horizon, with lounge chairs arranged alongside it. Clear blue skies and distant mountains are visible, enhancing the serene waterfront view. The modern building stands elegantly nearby, reflecting the vibrant outdoor atmosphere.

Apartment in Panamá

4.96 out of 5 average rating, 46 reviews

New studio apartment in front of the sea

Enjoy by the sea in Panama! Enjoy a full space with kitchen, air conditioning and access to amenities: social area, pool, co-working. The building stands out with an exciting rooftop, bars with a panoramic view. Explore restaurants and additional activities for a unique stay. Your oceanfront escape awaits! Book now and immerse yourself in the serenity and entertainment that only this place can offer.

Top guest favorite

A cozy living area features a light-colored sofa facing a wall-mounted television. A round table is set in front, and woven placemats add texture. Large windows showcase city views and provide natural light, while a bedroom is visible in the background, showcasing a spacious bed.

Apartment in Panamá

5 out of 5 average rating, 105 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Top guest favorite

An illuminated infinity pool reflects the city lights at night, providing a vibrant contrast against the dark sky. The pool's tranquil water appears inviting, with gentle ripples created by a slight breeze. The urban skyline is visible in the background, enhancing the overall serene ambiance.

Apartment in Panamá

4.99 out of 5 average rating, 100 reviews

Sky Lounge/ APT 1 BR-vista al Mar/Pool bar & GYM

Moderno apartamento de lujo en la Cinta Costera, ideal para ejecutivos, parejas o familias. Dormitorio amplio con vista al mar, baño privado, cocina y electrodomésticos. Diseño elegante con seguridad 24/7, gimnasio, piscinas, 4 restaurantes, bar y Sky Lounge. Ubicación privilegiada cerca de supermercados y excelente oferta gastronómica en Ciudad de Panamá. PANAMA

Top guest favorite

A stylish living area features a warm-toned sofa and modern circular coffee tables. Large windows with striped blinds allow natural light to enter, revealing a view of outdoor seating on a balcony. A round mirror and wooden sideboard add to the contemporary decor.

Apartment in Panamá

4.96 out of 5 average rating, 147 reviews

Superb Apartment In The Center Of Panama City

Luxurious, cozy, well-located 1-bed apartment in Panama City. Impeccably clean, stylishly furnished with a sofa bed. Experience the city's vibrant attractions, indulge in comfort, and make unforgettable memories. Your perfect getaway awaits! Book now for an exceptional stay.