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Vacation rentals in Panama Canal

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Top-rated vacation rentals in Panama Canal

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Apartment in Panamá
5 out of 5 average rating, 10 reviews

Luxury oceanfront apartment on the coastal strip

Apartamento contemporáneo en uno de los edificios mas lujosos de Panamá, ubicado en la Cinta Costera frente al mar, muy cerca de restaurantes, centros comerciales, cafe's, tiendas, supermercados y sitios turísticos de la ciudad Con su inmejorable ubicación y máximo confort, los huéspedes se pueden desconectar, relajarse y saborear este destino mágico que tiene su propio estilo, ademas de las instalaciones del edificio como Spa, restaurantes, gym, piscina, bar, billar, valet parking, entre otros

Top guest favorite
Apartment in Panamá
4.94 out of 5 average rating, 54 reviews

Panoramic Casco Viejo Lookout in The Sands

exquisite apartment blends cozy comfort with sophisticated luxury. Every detail radiates elegance, from the plush, high-end furnishings to the warm, inviting ambiance. The open-concept living area is perfect for relaxing or entertaining, with breathtaking views of the UNESCO World Heritage Casco Viejo framing the horizon. The compact kitchen has modern appliances, sleek countertops, and all essentials. With Casco Viejo vistas, this stylish retreat is perfect for exploring culture and history.

Guest favorite
Apartment in Panamá
4.95 out of 5 average rating, 56 reviews

Rooftop Pool • Centric • Metro 5 min • Parking

Moderno acogedor apartamento de 1 dormitorio en una de las zonas más céntricas y convenientes de Ciudad de Panamá. Ubicado a 5 minutos caminando de la estación de Metro Vía Argentina y rodeado de restaurantes, cafés, supermercados, bancos y todo lo necesario para estadía cómoda. Ideal para viajeros de negocios, nómadas digitales, turistas o parejas que buscan comodidad, seguridad y excelente ubicación. perfecto para descanso y productividad, excelente para estancias cortas y largas.

Top guest favorite
Apartment in Panamá
4.95 out of 5 average rating, 60 reviews

VIP Suite/ Sea View + Pool & Sky Lounge + Gym

Elegant studio suite with stunning ocean views, located on Panama city iconic Cinta Costera. Ideal for business travelers, couples, or tourists seeking style, comfort, and convenience. Features a full kitchen, spacious bathroom, fast Wi-Fi, and washer/dryer. Enjoy top amenities: pool, gym, sky lounge, game room, restaurants, and 24/7 security. Hosted with care by César & Claudia to ensure a warm and memorable stay in Panama . Remember to check our Guide. With parking include !

Superhost
Apartment in Panamá
5 out of 5 average rating, 4 reviews

2BR King Suite Ocean View, Casco, Canal 500MB WIFI

Experience Yoo Panama by world renown architect Philippe Starck. Massive unit 155 m2 / 1,700 ft2 ocean view apartment with an unobstructed view of Panama City/Pacific Ocean overlooking the Panama Canal, Casco Viejo & Cinta Costera. Views & location don’t get better than this. Each bedroom is a King Bed suite. The apartment is located on the prestigious Avenida Balboa. There is a grocery store and 3 of PA's most renown restaurants in the building. Blazing fast wifi at 500mgbs.

Top guest favorite
Apartment in Panama City
4.97 out of 5 average rating, 117 reviews

The View of Casco: Designer Loft with best Balcony

Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! ​Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. ​You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Guest favorite
Apartment in Panamá
4.89 out of 5 average rating, 225 reviews

Yoo Panama, 54th floor, comfortable and cozy.

Beautiful apartment located on the 54th floor of the most luxurious building in Panama. Areas designed by designer Philip Stark. It is 134 square meters, fully furnished, has a bedroom, walk-in closet, full bathroom, open living room and kitchen, half bathroom, terrace, and laundry room. The building is a unique place, with special and luxurious communal areas; 2 elegant restaurants; 2 swimming pools; gym; spa; 2 squash courts; poker room, lobby with pool table, etc.

Top guest favorite
Apartment in Panamá
4.94 out of 5 average rating, 62 reviews

Gorgeous Flat in the best location in Casco Viejo

This cute and stylish studio is perfectly located in the heart of Casco Viejo, Panama City’s most charming historic district. Recently renovated, it combines modern comfort with classic charm inside a beautiful colonial building—just steps from top restaurants, bars, monuments, and attractions. The space includes a comfortable sofa bed, making it ideal for a couple or a small family looking to enjoy the vibrant atmosphere of Casco right outside their door.

Top guest favorite
Apartment in Panamá
4.98 out of 5 average rating, 189 reviews

The apartment of a legendary Panamanian footballer

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Superhost
Apartment in Panamá
5 out of 5 average rating, 4 reviews

Signature Luxury Residence w/ Balcony + Terrace

One of the most spectacular residences in Casco Viejo — designed for those who want space, style, and an elevated experience. Just steps from the American Trade Hotel and surrounded by top restaurants, rooftop bars, and cultural landmarks, this home places you at the center of it all — while offering rare privacy and comfort. With both a private terrace and a balcony overlooking the historic surroundings, this is indoor-outdoor living at its finest.

Guest favorite
Apartment in Panamá
5 out of 5 average rating, 33 reviews

Private parking & rooftop | Studio Casco Center

This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Guest favorite
Apartment in Panamá
4.9 out of 5 average rating, 21 reviews

Luxury apartment in the heart of Panama

Lujoso y amplio apartamento ubicado en el centro de la Ciudad de Panamá, con una vista impresionante desde un piso 58 que te dejara sin aliento. Disfruta de una hermosa habitación, una moderna cocina totalmente equipada y un ambiente cómodo y sofisticado. Perfecto para viajes de placer o negocios, este espacio combina lujo, ubicación privilegiada y una experiencia única en las alturas de la ciudad.

Popular amenities for Panama Canal vacation rentals

  1. Airbnb
  2. Panama
  3. Panama Canal