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Apartment vacation rentals in Panama Canal

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Panama Canal

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Guest favorite
Apartment in San Felipe

En el corazón de Casco, remodelado y con parking

Escápate y descubre casco antiguo en este remodelado , cómodo y céntrico alojamiento en el corazón de Casco Viejo. Nuestra ubicación es lo mejor, te hará regresar. Cerca de restaurantes, Bares, Impresionantes Iglesias y Museos. La propiedad data del siglo XVII (1756) historia y buen ambiente. Podrás explorar la zona a pie, cocina full equipada, cama king europea, te sentirás como en casa, rodeado de las famosas paredes de calicanto. -Amplia sala de estar -Cocina full equipada

LocationFamilyGetting around

4.96 out of 5 average rating, 263 reviews
Top guest favorite
Apartment in San Felipe

The View of Casco: Designer Loft with best Balcony

Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! ​Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. ​You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

ValueFamilyView

4.98 out of 5 average rating, 134 reviews
Guest favorite
A modern living area is featured, showcasing a large wall-mounted television surrounded by a lighted panel. Seating is provided by a dark sofa with decorative pillows. A round dining table is visible in the foreground, complemented by four black chairs. Tall windows offer city views.
Apartment in Panama City

Luxury Oceanfront Resort 22nd Floor View, 200°

Luxury oceanfront apartment on the 22nd floor with breathtaking panoramic views of Panama Bay, the skyline, and historic Casco Antiguo. Located on the famous Cinta Costera, this resort-style apartment offers 2 bedrooms, 2 bathrooms, luxury kitchen, 65” TVs, washer/dryer, and sleeps up to 6 guests. Enjoy spectacular sunsets from the balcony and access to infinity pool, gym, and premium amenities, just minutes from restaurants, nightlife, and Panama City’s top attractions.

LocationValueCondition

4.85 out of 5 average rating, 73 reviews
Superhost
A bright bedroom features a spacious bed with a textured blue throw and rolled towels at the foot. Large windows provide an unobstructed view of the ocean, while a bedside table and a mirror enhance the room’s design. Natural light fills the space.
Apartment in Panama City

k*| Breathtaking Oceanview 1BR in Ave Balboa

Experience luxury in this oceanfront 1-bedroom apartment on Balboa Avenue with stunning views of the Pacific Ocean, Casco Viejo, and modern Panama City. Fully equipped for long stays with A/C, Water, TV, cable, and WiFi. Located in a unique building with amenities like Poin, a zipline between buildings, plus restaurants like Cielo, Osaka, and Patria. Walk to Cinta Costera and a subway station. Everything you need is right here—your perfect Panama getaway!

ValueLocationCondition

4.83 out of 5 average rating, 115 reviews
Guest favorite
Apartment in Panama City

Ocean View | Rooftop Pool | Luxury Stay

Wake up to a stunning ocean view right from your window at BrisaMarina. This luxury apartment is located in the spectacular The Sands building, right on the Cinta Costera. The modern and cozy space features bright natural light, air conditioning, high-speed Wi-Fi, and a fully equipped kitchen for your comfort. You’ll be just minutes away from restaurants, beaches, and top attractions. Perfect for couples, business travelers, or weekend getaways.

LocationFamilyKitchen

4.97 out of 5 average rating, 97 reviews
Top guest favorite
An inviting living area is featured, showcasing a modern grey sofa accented with decorative pillows. A round glass dining table is surrounded by chairs, and artistic wall frames complement the space. Natural light is filtered through elegantly layered window shades.
Apartment in Bella Vista

Apartamento de lujo Panamá centro, área bancaria

Contamos con una ubicación estratégica justo sobre la vía principal de Panamá (Calle 50) Bella Vista, te encontraras ubicado en el corazón del área bancaria. Si vienes por trabajo o vacaciones, este es el lugar ideal, encontrarás todo tipo de restaurantes a los alrededores, comercios, centro comerciales, tendrás la Cinta Costera a tan solo 10 minutos a pie donde podrás pasear o ejercitarte. Diversión y disfrute a pocos pasos

ValueLocationComfort

4.92 out of 5 average rating, 178 reviews
Guest favorite
Apartment in San Francisco

Apartamento completo en Panama

Este encantador apartamento está ubicado en uno de los mejores barrios de Panamá, San Francisco, un lugar céntrico donde encontrarás amplía gastronomía, lugares de diversión, cerca a estaciones de buses, y al centro comercial más importante de la ciudad, Multiplaza. Este apartamento céntrico y tranquilo es una oportunidad que no querrás dejar pasar. Ofrece la combinación perfecta de comodidad, belleza y ubicación conveniente.

ValueFamilyDecor

4.97 out of 5 average rating, 166 reviews
Guest favorite
A modern living area features a white sectional sofa adorned with colorful cushions. A sleek coffee table sits in front of a mounted television. Large windows provide expansive views of the city skyline, enhancing the bright and airy feel of the space.
Apartment in Bella Vista

Beautiful Apt, Best Location 2BR

Beautiful apartment, high floor up, with 2 bedrooms, 2 bathrooms, walking closet, and essential closet for the second bedroom. Extra twin bed available in the apartment. High speed internet, 300Mbps by Wifi aprox. , 600Mbps by cable. Social area on the roof with swimming pool, gym, sauna and bbq area. The building location is excellent, We are walking distance for grocery stores, restaurants, bank, Hilton Hotel&Casino.

FamilyLocationSleep quality

4.89 out of 5 average rating, 196 reviews
Superhost
Apartment in San Felipe

3B Mola Studio | Design By Paradox

Private 40 m² design studio in Santa Ana, about a 5-minute walk from Casco Viejo. Mola Space sleeps up to 3 guests with a Queen bed and sofa bed, and includes a full kitchen, private bathroom, air conditioning, hot water, fast WiFi, dining space, and a 1.8 m desk. Enjoy a projector with Roku and host-provided Netflix, Disney+, Max, and Prime. Guests have access to the shared balcony, patio, and paid laundry.

FamilyValueTV

4.87 out of 5 average rating, 436 reviews
Guest favorite
Apartment in Panama City

Moderno, céntrico y cómodo (001)

Moderno y acogedor estudio en el corazón de Panamá. Perfecto para explorar el Casco Antiguo, la Cinta Costera y más. Cocina completa, cama full, sofá cama doble, aire acondicionado, WiFi rápido y baño privado. Ideal para 1–4 personas. Acceso privado, ascensor y check-in autónomo. Rodeado de restaurantes, transporte y sitios turísticos. ¡Tu base ideal para conocer la ciudad!

ValueLocationCheckout

4.87 out of 5 average rating, 148 reviews
Guest favorite
Apartment in Panama City

Sky Lounge/ APT 1 BR-vista al Mar/Pool bar & GYM “

Moderno apartamento de lujo en la Cinta Costera, ideal para ejecutivos, parejas o familias. Dormitorio amplio con vista al mar, baño privado, cocina y electrodomésticos. Diseño elegante con seguridad 24/7, gimnasio, piscinas, 4 restaurantes, bar y Sky Lounge. Ubicación privilegiada cerca de supermercados y excelente oferta gastronómica en Ciudad de Panamá. PANAMA

ValueLocationLong stay

4.98 out of 5 average rating, 167 reviews
Guest favorite
The kitchen area features modern cabinetry and stainless-steel appliances, with an island that provides additional workspace. Large windows allow natural light to brighten the open space, while a dining table with seating is positioned nearby, offering a comfortable area for meals.
Apartment in Bella Vista

PH The Gray | Balcony Views · Pool · Gym

Wake up to panoramic views of Cerro Ancón from your private balcony — right in the heart of Calle 50, Panama’s financial and lifestyle hub. The Gray is a brand-new building offering resort-style amenities: rooftop pool, gym, and a fully equipped coworking space with high-speed Wi-Fi. You’ll also find restaurants and cafés inside the building itself.

FamilyValueLaundry

4.84 out of 5 average rating, 100 reviews

Popular amenities for Panama Canal apartment rentals

Private apartment rentals

Top guest favorite
A modern living space features a light-colored sofa facing a wall-mounted television. A round dining table with four chairs is positioned nearby. Large windows offer views of the cityscape, while natural light brightens the room. The elegant flooring complements the contemporary design.
Apartment in Bella Vista

departamento nuevo en el corazón de Panamá

LocationValueHospitality

4.94 out of 5 average rating, 51 reviews
Superhost
A rooftop infinity pool is illuminated with soft blue lighting, reflecting the city skyline at night. Lounging chairs are positioned along the pool's edge, while a stylish seating area is visible nearby, adding to the inviting atmosphere of the space.
Apartment in Panama City

Lindo Apartamento, frente al mar.

FamilyValueBathroom

4.81 out of 5 average rating, 83 reviews
Guest favorite
Apartment in Panama City

Luxury Stay & Panoramic Bay View in YOO Panama

LocationIndoor spacesLaundry

4.82 out of 5 average rating, 11 reviews
Top guest favorite
Apartment in San Felipe

Most Beautiful Loft in the Heart of Casco Viejo

LocationValueWalkability

5.0 out of 5 average rating, 36 reviews
Top guest favorite
Apartment in Panama City

Panamá Pacífico P.H. Centriqo: Cerca de Todo.

ValueFamilySleep quality

5.0 out of 5 average rating, 33 reviews
Guest favorite
Apartment in Panama City

The Sands Modern Oceanfront Apartment Panama City!

LocationIndoor spacesView

4.86 out of 5 average rating, 22 reviews
Top guest favorite
Apartment in Bella Vista

Apartamento moderno con piscina rooftop en Obarrio

LocationFamilyLaundry

4.92 out of 5 average rating, 36 reviews
Top guest favorite
Apartment in Panama City

Studio for the Coffee-Obsessed | near Casco Viejo

FamilyLocationWalkability

5.0 out of 5 average rating, 10 reviews