Guesthouse vacation rentals in Panama Canal

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Panama Canal

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favorite

Guesthouse in Gamboa

4.95 out of 5 average rating, 56 reviews

Gamboa Toucan Apartment casa # 126

Welcome to Gamboa! Only 35 minutes from downtown Panama, Gamboa. Situated in Soberanía National Park and on the shores of the Panama Canal, is a Mecca for Birdwatchers and Nature enthusiasts! Watch the wildlife right from the backyard of your fully equipped apartment. Feel the magic songs of thousands of birds welcoming the twilight of sunrise and dusk in this century old community. Easily explore wildlife on trials through the surrounding old growth jungle and by boat on the Panama Canal.

Sep 12 – 19

G$18,165 GYD per night

Guesthouse in Villa Rosario

5.0 out of 5 average rating, 4 reviews

Cosy, Private, Guesthouse, Pool, Central Local

Guest house, nice sized bed room with bath attached. Pool is shared with the owners. I am North American and my wife from Panama. We are middle aged, friendly, have no children, but a couple of nice dogs, chickens, and a rabbit. The wild birds have adopted us too as family. We are totally cement fenced and gated . Can assist with travel. We are centrally located to explore, min to mountains, beaches, and near many other destinations. Hablamos Español y Ingles. Have a US Phone.

Aug 11 – 18

G$8,627 GYD per night

Guest favorite

Guesthouse in Panama City

4.81 out of 5 average rating, 73 reviews

Efficiency Bungalow - Metropolitan Natural Park

Casita Curundu is located in a quiet and beautiful neighborhood next to the Metropolitan Natural Park. A naturalist delight right in the city, surrounded by an urban jungle forest teeming with birds and wildlife. An amazing place for a couple to stay - you’ll have all the privacy you need but still be close to all the great attractions and the large shopping and transportation hub Albrook Mall, Airport, Bus & Metro Station and yet removed from the hustle and bustle of the city.

Aug 15 – 22

G$10,836 GYD per night

Guesthouse in Alto del Espino

5.0 out of 5 average rating, 3 reviews

Tropical Suburban Splendor.

Forget your worries in this spacious and serene space. We are offering up our independent casita for those looking to explore the western communities of Panama. Located in La Choerra, we are a central to everything. If you are looking to visit the beaches, mountains, or lake we are 1 to 2 hours from it all. In the local area of La Choerra you will find all the shopping outlets and dining options you need for daily comfortable life. The casita is equipped with hot water and wifi.

Sep 26 – Oct 3

G$18,271 GYD per night

Guesthouse in Panamá

4.3 out of 5 average rating, 10 reviews

Convenient downtown suite with parking

This special place is close to everything, making it easy to plan your visit. 5-10 minutes to any attraction in Panama City. Assigned parking and two blocks from major bus stop that can take you anywhere in the city or accross the country. You will have the entire place for yourself with independent entry, air conditioning and kitchen. There are four grocery stores walking distance. You can exercise daily at a park located behind the property.

Aug 19 – 26

G$10,062 GYD per night

Guest favorite

Guesthouse in Panamá

4.86 out of 5 average rating, 7 reviews

Independent Attachment

Charming accommodation in Cerro Viento, Panama City, just 10-15 minutes from the airport. Attached to a house, this space is perfect for 4 people offers a bathroom, kitchenette with stove, refrigerator, microwave and electric coffee maker, with basic cooking utensils. Less than 5 minutes by car from Metromall Shopping Center and metro stations. Plus, enjoy entertainment with a 32-inch Smart TV and work area with stable internet and fast speed.

Jun 5 – 12

G$7,810 GYD per night

Guesthouse in Santa Rosa

Chagres River Lodge

You stay in our guest house on the River Chagres, it is a stone house with a beautiful Panama rancho over it, so the house stays nice and cool. In our garden you have large trees with many birds such as parrots. We have a sloth in the tree. In the morning you can hear the monkeys on the other side and you can explore the area with the canoe. Or take a dip in the river to cool off. A boat to Gamboa or the Panama Canal is a 10 minute boat ride.

Oct 6 – 13

G$26,827 GYD per night

Guesthouse in Panamá

New place to stay

Los Corcho Suite Airport II

Enjoy a modern mini-suite for 2 adults, only 8km from Tocumen Airport. Ideal for flight stops, business trips, overnight stay before a flight when you leave Panama and more. Relax in a closed community with parking. 10 minutes from Tocumen Airport, close to the Corredor Sur highway, Don Bosco Metro (Train) and shopping centers. 20 minutes to downtown and Casco Viejo. Private Driver Service available. Come and explore our city!

Nov 26 – Dec 3

G$7,799 GYD per night

Guesthouse in El Nazareno

4.76 out of 5 average rating, 42 reviews

NOE AND AMAS beautiful villa at El Nazareno

just 3 minutes from the interamerican highway, cozy and tranquil house,good ilumination, minisuper next door, free unlimited wi fi. free indoor private parking. completely private. guest are free to enjoy our red feet turtle sanctuary. red feet turtle are and endangered species. PLEASE, NO VISITORS ALLOWED. ALCOHOLIC BEBERAGES. ILEGAL SUBSTANCES. LOUD NOISES. OR UNRULY BEHAVIOR.

Aug 25 – Sep 1

G$7,523 GYD per night

Guest favorite

Guesthouse in Ciudad de Panamá

4.91 out of 5 average rating, 127 reviews

Independent Studio 9 km Airport @tocumen

Independent studio, It has A/C , with its bathroom. Located near Tocumen International Airport, 10 to 13 minutes by car. The Studio is Close to 2 Shopping Centers, Metromall and Los Pueblos. The residential area is safe when walking, organized and clean streets. We have the Cerro Viento Metro station outside in Metromall. Space to prepare light food.

Nov 18 – 25

G$6,157 GYD per night

Guest favorite

Guesthouse in Panamá

4.92 out of 5 average rating, 13 reviews

Apartment 10 minute from Tocumen Airport #1

medium apartment 10 minutes from Tocumen airport, offers all the comforts for a comforting stay and you can give your body the rest you need. you have access to the following services Wifi, Bathroom with hot/cold water, air conditioning, bed and sofa bed, kitchen, dining room, TV with cable, Towels and oversize.

Aug 6 – 13

G$7,744 GYD per night

Guest favorite

Guesthouse in Panamá

4.75 out of 5 average rating, 230 reviews

Private cottage in the heart of the city

two floor cottage with everything you need for a comfortable stay in Panama city. central location. Private entrance, private garden, private bbq. free wifi, cable tv, apple tv one double bed and one sofa bed for 2. kitchen with everything. AC bathroom accessories

Dec 29 – Jan 5

G$18,348 GYD per night