
Villa vacation rentals in La Mesa
Find and book unique villas on Airbnb
Quick stats about villa rentals in La Mesa

Total vacation rentals
Explore 10 vacation rentals in La Mesa

Nightly prices starting at
La Mesa vacation rentals start at G$12,548 GYD per night before taxes and fees

Verified guest reviews
Over 490 verified reviews to help you choose

Family-friendly vacation rentals
10 properties offer extra space & kid-friendly amenities

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
10 of La Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across La Mesa rentals

4.7 Average rating
La Mesa stays receive an average rating of 4.7 out of 5 from guests
Top-rated villa rentals in La Mesa
Guests agree: these villas are highly rated for location, cleanliness, and more.

1/2Acre•Lux•Pool•HotTub•SPA•PIT•ARCADE•Grill
Make dreams come true w/ this Upgraded Luxury Oasis, packed w/ 100+ amenities. From the stunning pool/spa, to the playground & arcades, a memorable vacation is waiting for you. A double master suite house, 2 kitchens, 2 laundry rooms on a half acre for the whole family to enjoy. Book Now 😊 18 min - San Diego Airport🛬/Downtown San Diego🏟️ 17 min - Balboa Park/Zoo🦁 22 min - Mission Beach/Pacific Beach 🏖️ 20 min - Mexico 🇲🇽 border 10 min - Berona Casino🎰 5 min - Lake Jennings🎣 22 min - Sea World🐳

Fun Get Away, Vaulted Ceiling, Pool, Hot Tub, New.
Enjoy a stylish experience at this centrally-located place. Great place to stay for those seeking an experience close to the beach and mountains and anywhere in San Diego you'd like to visit. 5 min from trails and Cowles Mountain. 15 min to Sea World, Animal Park, beaches, parks, downtown, Balboa park, the Midway museum, Coronado, Torrey Pines, La Jolla Cove, and much more! 2 min to a kid playground. Nice Villa in a really nice and Quiet Neighborhood, but will also accommodate your best party!

*Huge HelixCastle-PanoramicView/20+guests welcome
Welcome to our exquisite 5-bedroom (3 stories) home in the desirable neighborhood of Mount Helix in San Diego! This stunning residence is the perfect blend of modern elegance and exceptional comfort, making it an ideal choice for your stay in America's Finest City. Whether you're visiting San Diego for a family vacation, a romantic getaway, or a business trip, our Mount Helix castle, provides the perfect setting for an unforgettable stay. Book your stay with us today to create lasting memories!

☆🏘 Breathtaking 180º Views 🏝Hot Tub🏝 5☆ Reviews
🏝Welcome to the Harbor View Villa! 🏘A 3,500sqft villa with 6 bedrooms, 4 bathrooms and a 800 sqft walk-out deck. Complete with private rooftop hot tub, backyard, outdoor & indoor living. With 180º private day & night views from almost anywhere in the house! Make yourself at home in our Mission-Style Villa with stunning views of the boats in the Harbor, Downtown lights, and Coronado Island! 🗺Ideal for kids Perfect for MCRD & PLNU graduations (5min). Ask about early checkin / late checkout

5-bed Paradise Villa Pool, hot-tub massage chair
*EV charging available Welcome to Casa Cerro-my incredible chic high-tech modern villa in San Diego! This stylish place to stay is perfect for families and group trips. Its open and airy layout can accommodate up to 14 people. This completely remodeled home is furnished with all the luxuries of home and more that is powered by an iPad for you to use. I love technology. But don't worry you don't have to use it to power up the house, everything has traditional switches/remotes if you choose.

@Fantastic villa, giant pool, guest house, golf !
This unique fantastic villa with a separate pool house sitting on 1 acre with a spacious living space with large windows. Main house has 4 bedrooms with 2 baths, and a guest house has 1 bedroom with 1 bath. +8 car parking, nice privacy and a fantastic view! Brand new giant size SALT pool with huge size jacuzzi, pool toys, golf zone, a huge grass event field, game field, pool table, foosball, ping pong, Nitendo,2 fire pits and more! Truly one-of-a-kind property don’t miss out! ToT:COSD-00749

Hidden Villa with Beautiful Furnished Garden Patio
Close to everything, quiet and private. This beautiful 2 Bd Villa seems to be loved by all who stay here. The outdoor private patio feels like your in the forest. Gorgeous custom bath with large marble shower. Full size laundry. Great entertainment system, Roku, Amazon Prime. The home has open beam ceilings, lots of light and a fabulous patio fully furnished for guests, outdoor dining and barbecuing. The home is private, fenced, furry friends are welcome. 2 gig internet w/high speed router

East County San Diego Dream Luxury Estate
Welcome to this luxurious experience in the heart of Granite Hills. This spacious Rancho Santa Fe-inspired estate combines timeless design with modern comfort. With 4 bedrooms, 4 bathrooms, and thoughtful custom features throughout. High ceilings, natural stone flooring and a gourmet kitchen that brings everyone together. Views of city lights and mountain sunsets. A dreamy outdoor space with an oversized hot tub, sparkling pool, built in BBQ and cozy fire pit with views from room to room.

Luxury Dream Home Stunning 360 Views of SD
┏━━━━✦❘༻ WELCOME HOME ༺❘✦━━━━┓ ✦ Arguably the most stunning views in San Diego ✦ This Villa with a private Guesthouse captures all of San Diego including the Beaches, Coronado & Downtown ✦ Lounge in the numerous outdoor areas ✦ Walk the expansive wrap-around deck and choose where you'd like to see the sunsets and sunrises ✦ One of the few properties where you can see both! Climb the historic rock and be at the top of San Diego ✦ Famous Landmark - A piece of San Diego History

Gorgeous Beach Villa | Ocean Views + Sleeps 12!
Experience the ultimate family retreat in our spacious 6-bedroom, 4-bath home with breathtaking views of Mission Bay and the Pacific Ocean. Perfect for groups, it features two kitchens, multiple balconies, and a large backyard with a fire pit and grill. Walk to Ocean Beach and Sunset Cliffs or explore nearby attractions like SeaWorld and Balboa Park. Unwind with sea breezes, sunsets, and the sparkle of SeaWorld fireworks. Your unforgettable San Diego getaway starts here!

1stResorts.com WATER VIEW FAMILY VILLA A w/ HOTTUB
Brand New FAMILY Villa with Water Views from the kitchen / living area! Special reduction for week long stay!! Two level Villa. Large deck attached. Hot Tub, Barbecue Grill, Fire pit! Beautiful sunsets!! Come stay with us and enjoy all of San Diego's finest. We are located close to Balboa Park, Coronado and so many great venues and experiences or just stay on site and enjoy your very own Oasis!

Modern 3-Bedroom Villa, Luxurious Outdoor Oasis
Welcome to Your Perfect Spring Valley Villa! Nestled in the heart of Spring Valley, our charming spacious 3-bedroom, 2-bath home offers the perfect blend of comfort, style, and modern amenities. Whatever your planning, our home provides an ideal setting for a memorable stay. Need a rental car? We have a fleet of cars available right outside ready for use. Link to book available upon request.
Popular amenities for La Mesa villa rentals
Private villa rentals

The Bonita Bungalow

East County San Diego Dream Luxury Estate

Lux Villa: Heated Pool, Sauna, & Gym

Fun Get Away, Vaulted Ceiling, Pool, Hot Tub, New.

☆🏘 Breathtaking 180º Views 🏝Hot Tub🏝 5☆ Reviews

1stResorts.com AMAZING WATER VIEW PENTHOUSE HOTTUB

Hidden Villa with Beautiful Furnished Garden Patio

Private oasis
Luxury villa rentals

Spacious 4BD | La Jolla • Ocean Views • Jacuzzi

3680 Bayside Walk, A Bayside Marina

Cheerful 4-bedroom villa with free parking.

Large house with beautiful bay views
Villa rentals with a pool

Breathtaking Hillside Estate w/ Luxury Amenities

10AcreVilla,Heated*SaltPool,MtnView,Mini-Golf,BBQ

1 PRIVATE OCEAN VIEW ROOM IN LUXURY COASTAL HOUSE

LUX VACA | Solar-Heated Pool • Firepit • Games

2 Private Ocean View Suites-in Shared LuxuryVilla

Private oasis
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- Rosarito Beach
- SeaWorld San Diego
- Coronado Beach
- University of California-San Diego
- LEGOLAND California
- San Diego Zoo
- San Diego Zoo Safari Park
- Petco Park
- San Diego Convention Center E Ent
- Pacific Beach
- Balboa Park
- Tijuana Beach
- Pechanga Resort Casino
- San Diego State University
- Torrey Pines State Beach
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