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Vacation rentals in La Mesa

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Top-rated vacation rentals in La Mesa

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Guesthouse in La Mesa
4.96 out of 5 average rating, 250 reviews

Da Hui Hut - La Mesa’s best view and spa

Da Hui Hut is a very private oasis uniquely situated at the top of San Diego county's magnificent Mt. Helix. At roughly 1,300 feet above sea level, Mt. Helix is the crown jewel of natural landmarks in the area. The landscape provides bountiful views, and the large deck is positioned perfectly to see it all. It feels like you're on top of the city! Inside, guests will encounter Californian and Hawaiian inspired decor as they collide with wooden walls to compose a symphony of color and good vibes.

Top guest favorite
Guesthouse in La Mesa
4.98 out of 5 average rating, 136 reviews

NEW construction - Studio by Village of La Mesa

New studio - Attached Dwelling Unit (ADU) with a private entrance. Walking distance to the Village of La Mesa which has several restaurants, shops and a Vons. Very close to SDSU and quick access to multiple freeways that take you to beaches, mountains, SD Zoo, the nightlife in downtown SD (8, 94, 125). Access to shared laundry room, 2 parking spaces and its own outdoor area. AC & heat. WiFi. Netflix, Hulu with live TV, Apple TV, Disney +, Prime Video and HBO Max. Crib and high chair upon request

Top guest favorite
The exterior of a rustic stone cottage is framed by lush greenery and colorful plants. A seating area with chairs overlooks the surrounding garden and distant skyline. Sunlight illuminates the natural stone, highlighting the texture and structure of the cottage.
Guesthouse in La Mesa
4.9 out of 5 average rating, 447 reviews

Anna's Historic Stone Cottage w/panoramic View!

Welcome to Anna's Historic Stone Cottage! The 110 year old cottage has been transformed into the perfect combination of romantic and rustic for a dream-worthy getaway. The 280sq ft cottage features stunning, panoramic views of the San Diego skyline while offering rooftop seating for sunrise and sunset viewing. The Cottage is conveniently located 20 minutes from the world famous San Diego zoo and most other must-see, tourist spots. Amenities for special occasions offered too. Check out our menu!

Top guest favorite
Guesthouse in La Mesa
4.97 out of 5 average rating, 117 reviews

East Watch- a private getaway

East Watch is a 740 sq ft, 1 bedroom private retreat that provides the comforts and amenities of home with the style of a high-end hotel. All 5 to 15 min from shopping, downtown, and the beach. It's a short walk from Mt. Helix Park which offers a 360* view, weekday yoga, and stunning sunrises and sunsets. We have EV high speed car charging, a full kitchen with all appliances, workspace with dedicated fast WIFI, a spa shower, and super comfortable beds and pillows. Stay and let us charm you!

Top guest favorite
Bungalow in La Mesa
4.98 out of 5 average rating, 266 reviews

Townhouse - Hot Tub, Fire Pit La Mesa Village

Enjoy a stylish experience at this centrally-located bungalow. Just a short walk to La Mesa Village, where you can enjoy restaurants, coffee shops, boutiques, & more. The outdoor space has a hot tub, fire pit, yard games, & bbq. Hop on the trolley to get anywhere. Traveling with additional friends and family? We have the Casita de Pueblo located at the same location. Check it out under our other listings where you can book both. 20 min drive to the Beach, Downtown, Balboa Park, or Old Town

Top guest favorite
A quaint wooden counter is displayed, featuring a vintage cash register and an old-fashioned gramophone. Behind the counter, shelves are filled with various antique items and collectibles, creating a nostalgic atmosphere. A wooden chair sits invitingly in front of the counter.
Guesthouse in La Mesa
4.93 out of 5 average rating, 176 reviews

Granny Flat with Bedroom/Bathroom/Kitchen

My place is family friendly, close to comic con, , restaurants and dining, , the beach, , family-friendly activities , public transportation (trolley). You’ll love my place because of the peace and quiet. It's very quiet and private. PLEASE DO NOT BOOK IF YOU ARE PLANNING ON PARTYING. THIS IS NOT APPROPRIATE FOR MORE THAN 2 PEOPLE. There is a private entrance that you may use once you meet us.. We like to meet all our guests first and then you may come and go as needed. NO SMOKING NO PETS

Top guest favorite
The poolside area features a well-maintained saltwater pool reflecting the colors of the sunset. Comfortable seating arrangements, including lounge chairs and a cozy fire pit, are visible. Large umbrellas provide shade, and lush greenery adds to the serene ambiance.
Guesthouse in La Mesa
4.97 out of 5 average rating, 159 reviews

Vacation Paradise-Heated Pool+Hot Tub+FirePit+EV

Welcome to your personal resort! This is your private Guest House with a salt & heated pool + hot tub. Located in a very quiet & safe neighborhood in beautiful San Diego. Drive 15 minutes to the beach, downtown, La Jolla, Zoo, stadiums, Sea World, Convention Center + more. Hike next door at Cowell Mountain or Lake Murray. Smart TV, wifi, two zone AC, full kitchen, W/D combo, top quality finishes & furniture. Everything you need for memorable vacation! No smoking or vaping on the property.

Top guest favorite
A private deck is shown, featuring a red umbrella over a round table with four chairs. The entrance to the guest house is framed by glass doors and accompanied by a vibrant red door. Lush greenery and flowerbeds enhance the outdoor space.
Guesthouse in La Mesa
4.99 out of 5 average rating, 222 reviews

Stunning Guest House 15 min. from Zoo, Downtown

Stunning guest house that's 15 minutes to San Diego Zoo + downtown San Diego. The cottage is decorated with mid-century and one-of-a kind furniture in a comfy living space overlooking a gorgeous garden. Enjoy the the garden on your private deck, watch TV while relaxing in the handcrafted Nicaraguan rocker or 1950s Danish slipper chair. The cottage also has a comfy queen-sized bed and a full kitchen that's stocked with what you'd need. Oh, and all guests arrive to a homemade loaf of bread.

Top guest favorite
Home in La Mesa
4.9 out of 5 average rating, 198 reviews

Classic Mid-Century Mount Helix Home with Views

Located in the exclusive Mount Helix neighborhood of La Mesa, this property is conveniently located near the 8 and 94 freeways for easy access to explore the greater San Diego area. Attractions like the historic Balboa Park with the San Diego Zoo or Sea World are a 15-25 minute drive away. With spacious interior and exterior spaces at the property, though, you may not want to leave. The property includes 4 bedrooms and 2.5 bathrooms with furnished living room, family room and kitchen.

Top guest favorite
A cozy outdoor seating area is framed by large glass windows, offering sweeping views of a vibrant sunset over the landscape. Plush cushions rest on a spacious sofa, inviting relaxation as the sky transitions to hues of orange and pink.
Guesthouse in La Mesa
4.99 out of 5 average rating, 105 reviews

Hilltop AmazingVIEWS! Guest House with Balcony~

~PANORAMIC SUNRISE & SUNSET VIEWS~ ~PEACEFUL & PRIVATE~ ~CENTRAL LOCATION~ ~XL BALCONY~ OCEAN, Mountain, Harbor, & Valley VIEWS ~to Pt Loma & Coronado! Historic Mt Helix neighborhood. Extra large balcony to enjoy an outdoor living space! Private entrance 1 Driveway parking space NON SMOKING/VAPING of any substances on the property indoor & out Read about our limited ADD ON feature package: POOL/SPA/LOUNGE, requiring additional fees & approval terms that apply. Scroll down for details

Top guest favorite
Guesthouse in La Mesa
4.99 out of 5 average rating, 353 reviews

SDCannaBnB #1 *420 *parking *dog-friendly *hot tub

Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental!   Our casita is newly remodeled with luxury ammenities.  We proudly cater to the cannabis community and non-users alike.   Our casita has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest.  This ensures that every guest checks into a clean, fresh-smelling place that feels like home.   Our casita is located in our quiet, fully fenced in backyard, close to San Diego's attractions

Superhost
Home in La Mesa
4.81 out of 5 average rating, 111 reviews

Mountain View• Solar-heated Pool •HotTub •GameRoom

☀️Welcome to our fun, newly updated home in a quiet, secure neighborhood in La Mesa ☀️ 🌊Swim in our beautiful blue, solar-heated pool while enjoying an elevated mountain view, perfect for relaxation and fun. Unwind in our fantastic game room, equipped with a pool table, arcade machines and pop-a-hoop, offering endless entertainment for guest at all age. End the day in our in-home movie theater, where you can enjoy your favorite films in ultimate comfort. ☀️

Popular amenities for La Mesa vacation rentals

When is the best time to visit La Mesa?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$29,288 GYDG$29,497 GYDG$32,008 GYDG$27,824 GYDG$29,916 GYDG$32,008 GYDG$35,773 GYDG$32,008 GYDG$28,870 GYDG$28,661 GYDG$29,916 GYDG$30,962 GYD
Avg. temp15°C15°C16°C17°C18°C20°C21°C22°C22°C20°C17°C14°C

Frequently Asked Questions

  • What are the best places to stay in La Mesa?

    La Mesa has a range of options, with many visitors choosing stays near the downtown village area for easy access to dining, local shops, and parks. Residential neighborhoods around Lake Murray are frequently suggested for a quieter experience and access to green spaces.

  • What are the best things to do in La Mesa with kids?

    Families often explore parks like Harry Griffen Park, enjoy playgrounds, and visit local community pools. Interactive activities such as public art walks or checking out seasonal farmers markets provide fun ways to engage with the area.

  • What are some of the best things to do in La Mesa?

    Explore the historic La Mesa Village, walk scenic trails at Mission Trails Regional Park, or relax by Lake Murray's shoreline. Local art galleries, regular outdoor markets, and annual festivals reflect the area's community spirit.

  • How is the weather in La Mesa?

    La Mesa has a mild, sunny climate with winter temperatures around 50–66°F (10–19°C) and summer warmth reaching 66–77°F (19–25°C). Rain is most common in winter, while summers tend to be dry and clear.

  • What are the best places to visit in La Mesa?

    La Mesa Village has locally owned shops and public art, while Lake Murray is popular for picnics and water activities. Mission Trails Regional Park is frequently suggested for hiking and nature experiences.

  • What are some hiking trails in La Mesa?

    Many hikers enjoy the trails at Mission Trails Regional Park, including the Cowles Mountain climb for broad views. Around Lake Murray, a paved path is suitable for walking, jogging, or cycling among natural surroundings.

  • What are some family activities we can do in La Mesa?

    Families often visit community parks for playgrounds and picnics, explore the interactive public art in the village, or attend local events like farmers markets and community festivals. Outdoor activities around Lake Murray are also popular among all ages.

  • What are some of the best day trip ideas from La Mesa?

    Many visitors spend a day exploring beaches along the Pacific coast, discover museums and gardens in Balboa Park, or hike in the Cuyamaca Mountains. Exploring neighboring neighborhoods known for food and local art is also frequently suggested.

  • Are there any pet friendly accommodations available in La Mesa?

    La Mesa has a number of stays that welcome pets, especially in neighborhoods with easy access to parks and trails. Public spaces, such as Lake Murray and local dog parks, can make visits enjoyable for guests traveling with animals.

  • What are some local tips for visiting La Mesa?

    Explore the farmers markets for fresh, local produce, and check for community festivals throughout the year. Comfortable walking shoes and sun protection are helpful, as much of La Mesa is best enjoyed outdoors.

  • What is La Mesa known for?

    La Mesa is known for its historic village atmosphere, regular community events, and scenic outdoor spaces such as Lake Murray. Its blend of independent shops, public art, and accessible parks appeals to locals and visitors alike.

  • What are the best hidden gems to explore in La Mesa?

    Seek out the Secret Stairs for a locally famous walking route through hillside neighborhoods. Pocket parks, mural art throughout the village, and lesser-known hiking trails around Lake Murray provide inviting ways to explore.

  • What are the best foods to try in La Mesa?

    La Mesa has a diverse dining scene, with Mexican cuisine, classic diners, and family-style restaurants frequently suggested. Visitors often enjoy local bakeries, craft coffee shops, and places featuring California-inspired dishes.

  • What should I bring for a trip to La Mesa?

    Light, breathable clothing is useful for sunny days, while a light jacket or sweater can be helpful in cooler evenings or during winter months. Sun protection, reusable water bottles, and comfortable walking shoes support outdoor exploration.

  • What is the nightlife in La Mesa like?

    La Mesa has a laid-back nightlife scene centered on relaxed bars, pubs, and a few live music venues in the village area. Many spots feature local craft beers and occasional events such as open mics or trivia nights.

  • What are the most popular events or festivals in La Mesa?

    La Mesa frequently hosts community street fairs in spring and autumn, a car show known as Back to the 50's, and Oktoberfest celebrations in the village. Seasonal farmers markets are also community favorites.

  • Are there family friendly vacation rentals in La Mesa?

    La Mesa has a variety of family friendly vacation rentals, including homes near parks, playgrounds, and local attractions. Many guests choose neighborhoods close to Lake Murray and the village for accessible amenities and outdoor activities.

  • When is the best time to visit La Mesa?

    Late spring and early autumn are often recommended for comfortable temperatures and minimal rainfall. Summer brings clear, sunny days, while winter is cooler and sometimes rainy.

Quick stats about vacation rentals in La Mesa

  • Total vacation rentals

    Explore 550 vacation rentals in La Mesa

  • Nightly prices starting at

    La Mesa vacation rentals start at G$6,276 GYD per night before taxes and fees

  • Verified guest reviews

    Over 31,770 verified reviews to help you choose

  • Family-friendly vacation rentals

    260 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 170 rentals that welcome pets

  • Vacation rentals with a pool

    140 properties feature pools

  • Rentals with dedicated workspaces

    330 properties have a dedicated workspace

  • Wi-Fi availability

    540 of La Mesa vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Gym, BBQ grill, and Laptop-friendly workspace across La Mesa rentals

  • 4.9 Average rating

    La Mesa stays are highly rated by guests—averaging 4.9 out of 5!

Destinations to explore

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