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Private suite vacation rentals in La Mesa

Find and book unique private suite rentals on Airbnb

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Popular amenities for La Mesa private suite rentals

Family-friendly private suite rentals

Top guest favorite
Guest suite in San Diego
4.91 out of 5 average rating, 284 reviews

Cozy Guest Suite -Private 1 bd/1 bath

AndersonRating, 5 stars1 month ago
The most amazing, friendly, and gracious hosts! Ryan and Nicole made us feel so welcome—we felt right at home. The space was beautifully curated, which made it incredibly comfortable. There were plenty of amenities, such as a coffee machine with pods, a hairdryer, and an iron, along with a mini snack tray thoughtfully prepared by the hosts. There was plenty of street parking, and the neighborhood was quiet and peaceful. 10/10! Honestly, the best hosts I’ve ever met—they’re amazing people!
Superhost
Guest suite in Golden Hill
4.9 out of 5 average rating, 316 reviews

Studio + Loft! Near Petco, ConventionC & The Zoo!

zekeRating, 5 stars2 weeks ago
Very nice place! Parking is a bit hard to find later in the day
Top guest favorite
Guest suite in South Park
4.88 out of 5 average rating, 612 reviews

Welcoming Bungalow close to it all!

EmilyneRating, 5 stars1 month ago
We stayed here for a friends wedding weekend and loved exploring South Park. Was so cozy and just what we needed!
Guest favorite
Guest suite in La Jolla
4.96 out of 5 average rating, 352 reviews

La Jolla Cottage☀️ 5*reviews+everything sanitized!

CarolynRating, 5 stars4 months ago
The place was spotless. Extremely comfortable bed! I slept great! I didn't use the sofa so can't speak to that. A little traffic noise during rush hour, but nothing horrible. The location is excellent! Super easy to get to, and easy access to La Jolla, Pacific Beach, and I-5. Laura responded very quickly and was a pleasure to communicate with. The place has a friendly, welcoming vibe. I would happily stay there again.
Top guest favorite
Guest suite in Allied Gardens
4.96 out of 5 average rating, 342 reviews

Comfy, cozy updated Guest Home (patio, views, a/c)

IsabelleRating, 5 stars2 weeks ago
I really enjoyed my stay! The rental was in a great area and I felt very safe the whole time. Everything was just as described.
Guest favorite
Guest suite in Greater North Park
4.96 out of 5 average rating, 355 reviews

Urban Canyon Getaway

SethRating, 5 stars1 week ago
Wonderful area with lots to do and good restaurants nearby. Great area to stay! House was clean and private. David was a great host. Would definitely stay here again.
Top guest favorite
Guest suite in Point Loma Peninsula
4.94 out of 5 average rating, 533 reviews

Skyline Terrace by the Sea (Pt. Loma, Ocean Beach)

KatieRating, 5 stars1 week ago
Melissa’s place was super cute and a great place for my fiancé and I. Had all the amenities you would need and was in a quiet neighborhood with easy and accessible parking. It’s about a 1.5-2 mile hilly walk to the beach/Ocean Beach/restaurant area so I wouldn’t say it’s in a super walkable neighborhood but we had a rental car so it was easy for us to get around. Melissa’s guide book was amazing and we went to several of the recommended spots. This would be a great choice if you’re wanting to explore lots of areas of San Diego as it is centrally located and close proximity to highways.
Guest favorite
Guest suite in Greater North Park
4.95 out of 5 average rating, 592 reviews

Hip Guest Suite in North Park

EnaRating, 5 stars4 weeks ago
Jonathan's guest suite is a cute little, comfortable place to stay in. A lot of walkable places to try out and a close drive to other places you want to go see and enjoy. Really enjoyed the ceilings fans, they really keep the room fresh. No need to have the AC on specially during cold weather times. The skylight in the bathroom was unexpected, really nice feature. I kept thinking to myself how do I turn the light off until I realized it was light coming from the outside. Enjoyed our mine getaway.

Private suite rentals with a patio

Guest favorite
Guest suite in San Diego
4.98 out of 5 average rating, 168 reviews

Private Modern Suite – Patio, Parking, Laundry

MarisolRating, 5 stars1 week ago
My friend and I were comfortable in this spacious home this weekend. Everything looks exactly as shown in the pictures. Back patio was cute we got to take some pictures as well. Would definitely be staying here again!
Guest favorite
Guest suite in Golden Hill
4.96 out of 5 average rating, 100 reviews

Close proximity to Downtown, Gaslamp, Petco Park

PatriciaRating, 5 stars3 weeks ago
Spacious, serene AND close to everything, including walkable streets and a freeway. Those might seem like contradictory qualities but Steve’s clean, comfy Golden Hill apartment achieves it all. With the bedroom in the back, light-blocking curtains, and beautiful yard, this place is quiet and peaceful. Lots of extras, like special treats, washer/dryer, and beach towels/chairs, good WiFi prepared us for everything. Kitchen is exceptionally well equipped (except for a dishwasher; a huge sink largely makes up for it). In the past couple years it feels like on-street parking has been getting harder to find in the evenings, but still manageable, especially with walking to restaurants, Uber’ing, public transit, and daytime outings when parking is easy. Steve is so helpful and responds with lightning speed. Looking forward to our next visit.
Guest favorite
Guest suite in Bay Ho
4.92 out of 5 average rating, 163 reviews

The Bay Ho Back-house

KileyRating, 5 stars3 weeks ago
My fiancé and I stayed here being in town for a wedding and we couldn’t have booked a more perfect place for just the two of us! Amanda’s place was super clean and was exactly what we expected! The neighborhood was super quiet and safe. Amanda was super friendly and helpful. We would definitely stay here again! :)
Top guest favorite
Guest suite in Bay Park
4.97 out of 5 average rating, 117 reviews

Cozy guest suite walking distance to Mission Bay

SharonRating, 5 stars1 day ago
We loved this Airbnb! Upon arrival we were welcomed by our host, Grant. He helped us get into the unit and gave us a brief tour. We found the unit to be first class in every way - comfortable bed, quality linens, very clean, etc. There was a lot of attention to detail in this Airbnb. We were very pleased with this choice and would highly recommend it to anyone visiting San Diego.
Guest favorite
Guest suite in Greater North Park
4.97 out of 5 average rating, 209 reviews

Canyon-facing Studio with Private Entrance

LucyRating, 5 stars2 weeks ago
Loved our stay! The room was exactly as described with a great view of the canyon. The location was great and they were very clear instructions on how to access the airbnb. Would definitely stay again!
Guest favorite
Guest suite in Lakeside
4.94 out of 5 average rating, 103 reviews

Noonan's Nest

CynthiaRating, 5 stars3 weeks ago
Noonan's Nest is a spacious one-bedroom suite. We had plenty of room and didn't feel cramped compared to other locations where we have stayed. Our hosts were very friendly and readily shared information about area restaurants and other stores. It was conveniently located near our family, so we will definitely consider staying again on our next trip to the San Diego area.
Top guest favorite
Guest suite in Bay Park
4.96 out of 5 average rating, 112 reviews

**NEW** Casa de Palms - Gorgeous 1 BR Apartment.

HectorRating, 5 stars1 week ago
Overall a great experience! Very clear check in instructions and very clean and tidy place!
Top guest favorite
Guest suite in Encinitas
4.94 out of 5 average rating, 141 reviews

Zencinitas2

HannahRating, 5 stars2 weeks ago
Tadie and Mark's place was perfect! We're definitely putting it on our list to visit again since we're often in Encinitas. I'm currently 7 months pregnant and the bed was still very comfortable for me. Bathroom is well stocked with toiletries in case you forget something. Thank you for the nice stay!

Private suite rentals with a washer and dryer

Guest favorite
Guest suite in La Jolla
4.95 out of 5 average rating, 560 reviews

Oceanfront La Jolla Cove Studio-2025 Remodeled

LloydRating, 5 stars2 weeks ago
Anthony’s place is in a stunning location, with great beaches very close by. The studio is very clean and cozy, and Anthony was a great host. Anthony was very responsive and was a great host, would highly recommend staying here!
Superhost
Guest suite in San Diego
4.9 out of 5 average rating, 102 reviews

Artsy Studio with Private Patio–Long-Term Stays!

AustinRating, 5 stars2 months ago
Pam is amaaaazeballs! We
Top guest favorite
Guest suite in Greater North Park
4.98 out of 5 average rating, 250 reviews

North Park Hale - Newly Renovated

PaulRating, 5 stars1 week ago
Harold was a wonderful host, very fast at communicating and friendly. It’d love to stay here again the next time I’m in San Diego. There are tons of walkable restaurants and the neighborhood is fantastic with lots of street parking
Top guest favorite
Guest suite in El Cajon
4.97 out of 5 average rating, 118 reviews

Farmhouse Cottage Retreat with Beautiful View’s

SummerRating, 5 stars2 weeks ago
Our stay was wonderful. Great host. Very friendly. We felt at home and will come back again
Top guest favorite
Guest suite in Adams North
4.99 out of 5 average rating, 378 reviews

Casita Pacifica: Charming 2p Apartment w/ Jacuzzi

ThongsabayRating, 5 stars1 day ago
Absolutely love love love this small yet mighty place!! I was impressed! It was so cute and clean! The shower was amazing! The bed was comfortable and the back yard was great for my dog. The hot tub was a great addition to the place. Nice way to chill out after a long day of adventuring! I love the washer and dryer! I felt right at home! Kevin and his spouse were the nicest ever! They are quick to respond. They are so accommodating. I had car problems and they recommended a great car shop for me in the neighborhood! I would definitely stay again and look forward to coming back to San Diego! Thank you sooo sooo much for your hospitality! You are an amazing host! Loved everything about it!
Guest favorite
Guest suite in Greater North Park
4.9 out of 5 average rating, 161 reviews

Casa Feliz

IsabelRating, 5 stars1 week ago
Casa Feliz was a lovely spot to stay in — quaint, cozy, and even cuter than expected. Although I was only there for a short time, the home exceeded my expectations and was stocked with everything one could possibly need during their stay. Claudia & Steve were kind, communicative, and their check-in instructions were clear and easy to follow, which made the whole experience smooth and enjoyable. I’d love to stay again if I find myself in San Diego in the future!
Top guest favorite
Guest suite in Greater North Park
4.99 out of 5 average rating, 278 reviews

Walkable North Park Casita

TinaRating, 5 stars2 weeks ago
Dana’s casita truly felt like home. From the moment we walked in, we noticed every small, convenient detail—from the decor to the thoughtfully placed light switches. The bed was comfortable, the living space perfect for winding down, the kitchen in great condition, and the bathroom squeaky clean. Our dog loved the neighborhood too! It’s walkable to restaurants, cafes, and the famous Balboa Park, which made our stay even more enjoyable. We only wish we stayed longer. Dana was a gracious, responsive host who made everything easy from start to finish. We’ll definitely bookmark this gem and keep it in mind for future visits!
Guest favorite
Guest suite in Golden Hill
4.96 out of 5 average rating, 125 reviews

2748 Treat St. Private Suite/Kitchenette

RachelRating, 5 stars1 week ago
Loved this spot! very quiet, large bedroom, comfy living area. super close to activities and downtown!

Quick stats about private suite rentals in La Mesa

  • Total rentals

    40 properties

  • Nightly prices starting at

    G$8,366 GYD before taxes and fees

  • Total number of reviews

    4.9K reviews

  • Pet-friendly rentals

    10 properties allow pets

  • Rentals with a pool

    10 properties have a pool

  • Rentals with dedicated workspaces

    20 properties have a dedicated workspace

Destinations to explore