Villa vacation rentals in La Mesa

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Top-rated villa rentals in La Mesa

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Guest favorite
The backyard pool is surrounded by stone walls, featuring a gentle waterfall and illuminated by string lights. Floating toys rest on the water's surface, and tropical greenery is visible in the background, enhancing the outdoor relaxation space.
Villa in Lakeside
4.97 out of 5 average rating, 35 reviews

Lux•6BR•7BA•Pool/SPA/Golf/Grill/Games/Sleep 40+

Make dreams come true w/ this luxurious resort-style home, packed w/amenities. From mini golf, pool, spa, playground, game room & arcades, relaxation & entertainment comes easy. 4,000 sq ft of living space on quarter acre, plenty of room for the whole family. Over 100 amenities Book Now 😊 19 min - San Diego Airport🛬/Downtown San Diego🏟️ 18 min - Balboa Park/Zoo🦁 23 min - Mission Beach/Pacific Beach 🏖️ 28 min - Mexico 🇲🇽 border 10 min - Barona Casino 🎰 5 min - Lake Jennings🎣 22 min - Sea World 🐳

Guest favorite
Villa in Mission Hills
5 out of 5 average rating, 6 reviews

Amazing WaterView Penthouse w/AC

AMAZING WATER VIEW PENTHOUSE!! Over 300 5 star reviews from our listings! Perfect for Executives, Quiet mature couples, Healthcare Professionals, Physicians/Traveling Nurses. Immaculate Luxury/Centrally-located. Peaceful, family friendly, every amenity. Private hot tub/private deck/patio furniture/private bbq grill/private fire pit/5 Star Resort Experience/robes/slippers, hot tub towels, fully stocked kitchen/pots/pans/spices/cookware/stemware/dishes/flatware/WiFi/Smart TVs/cable/Netflix/YouTube

Top guest favorite
A charming exterior view of the house is framed by lush greenery and vibrant flowers. A winding stone pathway leads to the front entrance, where a few steps are visible. The natural landscaping includes various plants, creating a welcoming and serene atmosphere.
Villa in Hillcrest
4.78 out of 5 average rating, 50 reviews

Vintage Home on the Canyon’s Edge

We’re excited to offer our beautiful home in University Heights- just 5 mins from downtown SD. Perched on the edge of a peaceful canyon, the house is surrounded by nature, offering a serene escape while keeping you close to the city’s best attractions. Home features: • 2 comfortable bedrooms • A dedicated study that can double as a third bedroom • 2 full bathrooms • Fully equipped kitchen • Smart TV, WiFi, washer & dryer • A private balcony overlooking the canyon and our inviting hot tub

A spacious balcony extends along the home, providing sweeping views of the surrounding landscape. The railing casts shadows on the floor, while lush greenery and distant hills are visible in the background under a clear blue sky.
Villa in El Cajon
4.66 out of 5 average rating, 62 reviews

*Huge HelixCastle-PanoramicView/20+guests welcome

Welcome to our exquisite 5-bedroom (3 stories) home in the desirable neighborhood of Mount Helix in San Diego! This stunning residence is the perfect blend of modern elegance and exceptional comfort, making it an ideal choice for your stay in America's Finest City. Whether you're visiting San Diego for a family vacation, a romantic getaway, or a business trip, our Mount Helix castle, provides the perfect setting for an unforgettable stay. Book your stay with us today to create lasting memories!

Guest favorite
A spacious living area features large floor-to-ceiling windows showcasing panoramic views of the outdoor pool and surrounding landscape. A pool table is positioned in the center with comfortable seating nearby. Natural light floods the room, highlighting the modern decor and open layout.
Villa in El Cajon
4.96 out of 5 average rating, 144 reviews

@Fantastic villa, giant pool, guest house, golf !

This unique fantastic villa with a separate pool house sitting on 1 acre with a spacious living space with large windows. Main house has 4 bedrooms with 2 baths, and a guest house has 1 bedroom with 1 bath. +8 car parking, nice privacy and a fantastic view! Brand new giant size SALT pool with huge size jacuzzi, pool toys, golf zone, a huge grass event field, game field, pool table, foosball, ping pong, Nitendo,2 fire pits and more! Truly one-of-a-kind property don’t miss out! ToT:COSD-00749

Superhost
An aerial view captures a spacious villa with a unique architectural design. Surrounding the home, a well-maintained outdoor area includes a private swimming pool, lounge seating, and landscaped gardens. Solar panels are visible on the roof, emphasizing sustainable features in this inviting retreat.
Villa in Ocean Beach
4.76 out of 5 average rating, 46 reviews

Historic Villa, Blocks from the Beach, Ocean Views

Built in 1923, this beach town retreat has tons of old world charm with all the modern amenities. Only 6 blocks to the beach, you couldn't ask for a better location. Dog Beach, Sunset Cliffs and some of the best bars, restaurants and vintage shops in all of San Diego are just outside your doorstep. ☞ 3 Bedrooms ☞ Private Hot Tub ☞ Private Swimming Pool ☞ Outdoor Dining ☞ Ocean Views (perfect for sunset cocktails) ☞ Outdoor Grill ☞ Bikes to enjoy the neighborhood ☞ Chef's Kitchen

Superhost
Villa in Rolando
4.93 out of 5 average rating, 54 reviews

Stay&Play SDSU- Pool •HotTub •GameRoom •SunsetView

☀️Welcome to your luxurious San Diego getaway! ☀️ This spacious 5-bedroom, 2-bathroom 2-level home is perfect for groups and families. Dive into the sparkling blue pool, unwind in the 6-person hot tub, or relax in the cozy outdoor seating areas. Enjoy stunning views from the balcony overlooking the pool, perfect for sunsets. With a central location, plenty of space to relax, and a mix of comfort and elegance, this home is ideal for exploring or unwinding on your San Diego adventure!

Top guest favorite
A private pool is surrounded by a stone patio and lounge seating. The house features large windows and a covered dining area with a patio umbrella. Lush greenery complements the tranquil outdoor space, emphasizing the welcoming atmosphere of the backyard.
Villa in La Mesa
5 out of 5 average rating, 55 reviews

Casa Charles, Tropical backyard, Pool & Pizza oven

This beautiful family home is a entertainment paradise with a large gourmet kitchen with plenty of pots and pans, dished and kitchen ware, even the spices to cook up a delicious family dinner. but you'll be sure to enjoy the tropical backyard with a bocce court, that includes a pool, a hot tub, an outdoor wood fireplace, a gas fire pit and even a wood fire pizza oven - You're freeway close to everything San Diego has to offer when you stay at this centrally-located retreat.

Superhost
Villa in Kensington
4.83 out of 5 average rating, 6 reviews

The Kensington Canyon Estate

The Kensington Canyon Estate is a 5 bedroom 4 bath charming historic Tudor-style home located in Kensington, San Diego, an upscale enclave on the southeast rim of Mission Valley. Kensington is picturesque, with attractive (and upscale) traditional-styled homes. It's a peaceful pocket amid the San Diego urban crawl. Kensington offers a miniature "Main Street" along Adams Avenue, replete with coffee shops, upscale restaurants, a branch library and friendly neighborhood park

Top guest favorite
A living area features a mix of seating options, including a blue sofa and a red chair. A wooden coffee table is positioned centrally. Floor-to-ceiling shelving holds a variety of books and DVDs. A dining area is visible, accompanied by natural light from nearby windows.
Villa in Mission Hills
4.98 out of 5 average rating, 94 reviews

Hidden Villa with Beautiful Furnished Garden Patio

Close to everything, quiet and private. This beautiful 2 Bd Villa seems to be loved by all who stay here. The outdoor private patio feels like your in the forest. Gorgeous custom bath with large marble shower. Full size laundry. Great entertainment system,DVD's, Roku, Amazon Prime. The home has open beam ceilings, lots of light and a fabulous patio fully furnished for guests, outdoor dining and barbecuing. The home is private, fenced, furry friends are welcome.

Top guest favorite
The villa is illuminated at night, showcasing a spacious outdoor area with a blue pool and stone patio. Surrounding seating arrangements create a welcoming atmosphere, while palm trees and distant city lights enhance the tranquil ambiance.
Villa in La Mesa
4.9 out of 5 average rating, 278 reviews

Private Villa: Pool, Slide & Hot Tub

Summary: * Spacious: 5,000 SF indoor living space & 10,000+ SF outdoor living space * Fantastic Pool: Complete with waterslide, cave /grotto & multiple fountains / waterfalls * Relaxing Hot Tub: 5 hours of free heating daily from 5pm-10pm * Event Policy: No weddings, events, or parties with 16 or more guests * Accommodates: This home can accommodate up to 16 guests /see “more things to note" for more info on beds/air mattresses

Superhost
A modern living area is highlighted by a spacious sectional sofa adorned with cushions, alongside a round black coffee table. Natural light floods the room through multiple windows, illuminating the elegant marble flooring and the dining space with a table in the background.
Villa in Mira Mesa
4.82 out of 5 average rating, 55 reviews

Beautiful house in mira mesa

Get ready to enjoy a bright and spacious home right in the heart of Mira Mesa! Just 20 minutes from downtown, the airport, top attractions, and plenty of shopping, it’s the perfect spot for large families or groups of friends eager to experience the best of San Diego. Here, you’ll feel right at home while soaking up all that sunny San Diego has to offer For your safety,security camera in the front door

Popular amenities for La Mesa villa rentals

Quick stats about villa rentals in La Mesa

  • Total vacation rentals

    Explore 10 vacation rentals in La Mesa

  • Nightly prices starting at

    La Mesa vacation rentals start at G$12,520 GYD per night before taxes and fees

  • Verified guest reviews

    Over 450 verified reviews to help you choose

  • Family-friendly vacation rentals

    10 properties offer extra space & kid-friendly amenities

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    10 of La Mesa vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across La Mesa rentals

  • 4.7 Average rating

    La Mesa stays receive an average rating of 4.7 out of 5 from guests

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