
House vacation rentals in La Mesa
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Top-rated house rentals in La Mesa
Guests agree: these houses are highly rated for location, cleanliness, and more.

Walk to Balboa Park and Hillcrest from an Immaculate Home
Take a stroll through the park, then unwind with a leisurely dinner under the festoon lights. Classic crown molding, hardwood floors, and pared-back tones of gray and taupe create an air of calm at this elegant haven spread out over 1500 square feet. You will find the space charming & spacious with over 1500 sq. feet. This single level property is the lower level of a historic duplex. Hardwood floors, crown molding, gas fireplace and laundry room. Street parking is usually readily available. This A+ location of Banker's Hill is NOT impacted by air plane noise. Enjoy the entire lower level duplex and use of the back yard with patio set for dining. Please note the upper tenant may also want to use this space so this area could be shared. We would love to greet you but are also fine with allowing you to access with a code on the front door. We live nearby and are happy to make suggestions for dining or things to do. Located near numerous restaurants, and Balboa Park, Hillcrest, the zoo, Downtown, Little Italy, and the Convention Center are all within 10 minutes. Be at the beach in less than 15 minutes. The bus line runs up First Ave for easy access to Downtown and Uptown. Near trolley and train station. We are within 10 minutes to the San Diego International Airport and a quick Uber ride to Downtown, Little Italy. Walk to the heart of Hillcrest, Balboa Park and the Zoo. Be at the beach in less then 15 minutes. Central location near the I-5, I-163 & I-8. Because of the hardwood floors, you will hear the footsteps above. The kitchen is well stocked if your a cook and we have an area where you can set up your laptop. wireless available and 3 smart TV's for your enjoyment. Small market less than 1 block away.

Family Fun! Game Garage + Big Yard + Free Parking
Embodying the epitome of cool! This home has the perfect blend of a vintage feel with a modern touch. Stepping inside, youâre greeted by an atmosphere of fun & creativity. A large private serene retreat in the backyard w/abundant seating and fire pit. Huge 3-car garage bonus space with games. Located just minutes from downtown La Mesa, many dining options & conveniences. Everything you need & more! Distance to: San Diego Zoo: 18 min Sea World: 23 min SDSU: 13 min Airport: 19 min Gaslamp: 18 min

XTRA 10% OFF until Nov: Pool, outdoor fire pits, c
Find your family's dream spot in San Diego! Our cozy house sits on a quiet hill, offering privacy and amazing sunset views. Dive into our pool year-round (heating at an additional cost), roast marshmallows by the fire, and cook up fun meals together. With 3 bedrooms and 2 bathrooms, itâs perfect for families, accommodating up to 9 guests. Plus, we're close to all the best attractions. Want a vacation you'll always remember? Send us a message to make it happen! đ đ We have 3 comfy beds that can

2 Bed Hidden Oasis | Garden, Laundry, Parking
Capture the essence of San Diego in our Hidden King Suite with Garden hosted by Ethos Vacation Homes. The peaceful property features elite comfort for up to 4 guests with beautiful outdoors and garden, off-street parking, A/C and heating, FREE laundry, comfortable king and queen size beds, plenty of sheets and towels, a large HDTV, Netflix, Max, Hulu, Showtime, Disney+, Apple+, and ESPN+. This spacious San Diego vacation rental home has everything you need for your California Dreaming Vacation!

Golden Hill Tree House
The Golden Hill Tree House is an urban oasis hiding in the branches of two mature trees in the heart of San Diego. While you enjoy elevated privacy you can also treat yourself to a soaker tub with double shower heads or settle down in a cozy reading nook to enjoy a good book! You'll also be walking distance to some amazing restaurants and super close to the best of San Diego, including downtown, the beach and the zoo! It's a perfect place to recharge after a long day of business or pleasure!

Sunny & Spacious 3BR Retreat w/ Parking & A/C
Centrally located in La Mesa is this newly refurbished home ideal for business or pleasure with all of lifeâs little luxuries waiting for you to enjoy. The home features open concept living with a gourmet kitchen, a chic dining space, 3 beautiful bedrooms, 2 modern bathrooms and an expansive yard with an outdoor lounge. Walk 10 mins to Grossman Center with a Target, restaurants, cafes, a cinema & Walmart or drive to the heart of San Diego and all its attractions just 20 mins from your door.

Bright and spacious home with views, pool & spa.
This beautiful and recently remodeled, open-floor plan home is conveniently located directly across from Cowles Mountain, one of San Diego's most visited hiking trails. Each bedroom has its own full bathroom. Perfectly located for the outdoorsy family. Tons of hiking and mountain bike trails are just across the street. Only 15 min. away from beaches, zoo, & Sea World. Gaslamp/Downtown is only 20 min. by car. After a day of exploring, come home to a newly-built, salt-water pool and spa.

Cottage in the Garden! New! Modern!
COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!

Zen Retreat: 3-Bedroom Oasis near La Mesa Village
Relax in this charming 3-bedroom, 1-bathroom home located just 1 mile from the heart of Historic Downtown La Mesa Village. Nestled in a quiet, central neighborhood, this cozy retreat offers easy access to major freeways, top-rated restaurants, and the local trolley line making it a breeze to explore the best of San Diego. Within 10 to 15 miles, youâll find yourself in iconic destinations like Downtown San Diego, Balboa Park, Coronado Island, scenic beaches, and beautiful mountain trails.

SDCannaBnB #2 *420 *parking *dog-friendly *hot tub
Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental!  Our studio is newly remodeled with luxury ammenities. We proudly cater to the cannabis community and non-users alike.  Our studio has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest. This ensures that every guest checks into a clean, fresh-smelling place that feels like home.  Our studio is located in our quiet, fully fenced in backyard, close to San Diego's attractions

(Relist!) Relax at a Stunning 1931 Historic Tudor!
Come & enjoy our 1931 historic tudor home! Beautifully rebuilt within the last 2 years. This house has a huge front lawn and space to roam. Enjoy the serenity this large property has to offer. Three peaceful patios to enjoy your morning coffee. The kitchen has an 48-inch 1950âs oven for the chef in the family. Bay windows, arched entryways and original light fixtures make this such a charming place to stay. Centrally located to enjoy everything San Diego & La Mesa has to offer.

Peaceful Casita | Firepit ⢠Near SDSU
Welcome to our cozy home, perfect for couples visiting the area. It's also a great spot for SDSU parents visiting their kids. Conveniently close to the campus but far enough to enjoy some peace and quiet. If you enjoy this listing, click the heart icon ⤠in the top-right corner to bookmark it for easy access! Minutes from key attractions: â 6 min to SDSU/Viejas Arena â 14 min to Balboa Park â 17 min to Downtown SD (Gaslamp) â 19 min to San Diego Zoo â 21 min to the Airport
Popular amenities for La Mesa house rentals
House rentals with a pool

Bright Contemporary 5-Bedroom Oasis, Pool and Yard

Lionhead - Private Boutique Home

Stunning San Diego Home w/Pool,Spa,Outdoor Oasis

Custom Guesthouse, Balboa Park/Zoo/Hillcrest& pool

Updated TownHome, Great Location, Fantastic Views

Designer Luxury Rental With Pool

Modern Hilltop Home: Roomy, Views, Family-Friendly

Luxe Home w. Serene Backyard Spa
Weekly house rentals

Tiny Home with a View

Shadow House Mt. Helix

Airbnb Luxe: Designer Pool, Fitness and Office

Discover La Mesa: Your Perfect Cozy Base

Helix Haven

Modern, Private, & Stylish Home

Entire house, fenced yard, and driveway

25% off â˘Hot tubâ˘BBQâ˘Patioâ˘4 min SDSUâ˘CentralSD
Private house rentals

Surreal Serenity Escape wIth Game Room, Pool & Spa

Welcome New & Improved! Your Home Away from Home

Serenity in San Diego

Cozy quiet getaway, great mattress (1-br)

XLarge Artist's Retreat w/private patio/parking

ModernCoastal I View I Pool ITub

Charming Cozy Studio Centrally Located

Serene retreat with valley view!
When is the best time to visit La Mesa?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$37,477 GYD | G$37,477 GYD | G$39,780 GYD | G$37,686 GYD | G$38,524 GYD | G$44,805 GYD | G$52,342 GYD | G$44,176 GYD | G$38,733 GYD | G$38,524 GYD | G$37,477 GYD | G$40,408 GYD |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Quick stats about house rentals in La Mesa

Total vacation rentals
Explore 300 vacation rentals in La Mesa

Nightly prices starting at
La Mesa vacation rentals start at G$4,187Â GYD per night before taxes and fees

Verified guest reviews
Over 13,300 verified reviews to help you choose

Family-friendly vacation rentals
190 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 100 rentals that welcome pets

Vacation rentals with a pool
80 properties feature pools

Rentals with dedicated workspaces
180 properties have a dedicated workspace

Wi-Fi availability
300 of La Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across La Mesa rentals

4.9 Average rating
La Mesa stays are highly rated by guestsâaveraging 4.9 out of 5!
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- Family-friendly rentals La Mesa
- Rentals with a beach view La Mesa
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- Rentals with a fire pit La Mesa
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- House rentals San Diego County
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- Rosarito Beach
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