
Smoking friendly vacation rentals in La Mesa
Find and book unique smoking friendly rentals on Airbnb
Quick stats about vacation rentals that are smoking-friendly in La Mesa

Total vacation rentals
Explore 10 vacation rentals in La Mesa

Nightly prices starting at
La Mesa vacation rentals start at G$10,453 GYD per night before taxes and fees

Verified guest reviews
Over 1,060 verified reviews to help you choose

Family-friendly vacation rentals
10 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 10 rentals that welcome pets

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
10 of La Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across La Mesa rentals

4.8 Average rating
La Mesa stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated smoking friendly rentals in La Mesa
Guests agree: these smoking friendly rentals are highly rated for location, cleanliness, and more.

Paradise View Staycation Q Bed, Sofa-bed *420 *
Welcome to our Spring Valley Retreat, escape to our charming granny house nestled in the heart of Spring Valley! Discover the tranquility of our 1 bedroom 1 bath sofa bed equipped kitchen, catch up work with high speed wi-fi in the design work place Unwind in our backyard oasis complete with inviting outdoor.furniture Conveniently located 25 minutes away from Downtown San Diego and Airport and short drive from pristine breaches. 5 minutes drive to grocery store and coffee shops/shopping center.

San Diego Mountain Retreat
3 bedroom 1 bathroom loft (2 separate sides) open concept guest house. Very peaceful East San Diego getaway. Enjoy beautiful ocean and Mountain Views during the day then relax in the jacuzzi with breath taking sunsets and the city lights at night. Best views in San Diego! Only 25 minutes from the SD airport and beaches. Minutes away from 2 local wineries and casinos. House sleeps 6 but you can invite guests up for the day for a fee. Event prices will be discussed per event. We live in main home

Romantic Private Garden Studio Near Downtown
A magical private garden surrounds a tiny studio (240 sq ft) with kitchenette in historic residential district, 10 blocks to East Village and Petco BallPark, near Gaslamp Quarter, and one mile to Convention Center and downtown. Easy access to freeways, very close to Balboa Park, San Diego Zoo, and Coronado Island. Airport and train station less than 15 min. We offer a safe, sweet, and contemplative getaway near the city, with WiFi but no TV. One pet OK only with prior approval. 420 friendly.

SDCannaBnB #1 *420 *parking *dog-friendly *hot tub
Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental! Our casita is newly remodeled with luxury ammenities. We proudly cater to the cannabis community and non-users alike. Our casita has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest. This ensures that every guest checks into a clean, fresh-smelling place that feels like home. Our casita is located in our quiet, fully fenced in backyard, close to San Diego's attractions

Mid-Century Style Family House with Spa
This home is the epitome of 1950’s luxury. A perfect family oasis, you won’t even want to leave the property. Beautiful Mt. Helix mid-century modern family home with incredible views, designed by architect of original Las Vegas Desert Inn situated on nearly an acre. Less than 20 minute drive to beaches/Zoo/Sea World/Downtown. With a swimming pool, jacuzzi, and AC. Surrounded by orange, lemon, pomegranate trees and herb garden. No loud parties please, this is a quiet community.

ROMANTIC AND SPACIOUS JACUZZI SUITE!
A completely private sanctuary with its own keyed entrance and no shared spaces. Enjoy breathtaking sunrises and sunsets from two private balconies, unwind in the jacuzzi, and relax in a suite designed for comfort. Plush mattresses and linens, a well-equipped kitchenette (microwave, Keurig coffee maker with coffee, mini-frig/freezer, toaster, two burner cooktop, kitchenware), and bathroom essentials including an iron/ironing board and hair dryer ensure a seamless, restful stay.

Upgraded Pt Loma Panoramic Views - 1 Bedroom Suite
Brand new full kitchen installed November 2025. Enjoy your home away from home and beautiful Pt Loma. With an expansive view of the gorgeous San Diego Bay & Shelter Island you can enjoy a comfortable space with luxury amenities. A spacious oasis to escape the hustle and bustle of the city, but close enough for a night out on the town. If you’d rather stay in and enjoy the views, relax on the patio, soak in the hot tub, or have a drink by the fire pit with your fur baby.

Fletcher Hills - modern 1 BR.Easy, no step access.
** 36 hours between check-ins. Thorough cleaning and sanitizing.. Four night minimum stay. Dogs ONLY are welcomed on a case by case basis. They must be house trained and are not permitted on any furniture. If you instant book, you must contact me about your pet within 24 hours. Smoking is permitted in the outside areas - patio, gazebo, yard. Easy freeway access helps any commute to downtown and area attractions. Having your own vehicle is the best way to get around..

Hot Tub Getaway by the Coast
Enjoy quality time with your entire family at this well-equipped home featuring a hot tub and tons of kids amenities! We cater to families. High-speed wifi, toys, and an outdoor wood-burning fire pit. Situated within walking distance to the Marina, downtown 3rd Ave, a 5 min drive to Sesame Place, a 15 min drive to the Zoo, downtown San Diego, liberty station, sea world, beaches, and more! This property is equipped with external security cameras for added safety.

San Diego's Finest: Private Hot Tub and Fire Chat
Newly renovated accommodations await with this centrally located 2-bedroom, 1-bath home close to popular attractions like beaches, the Zoo, Sea World, Bonita Golf Course, and Downtown San Diego. Convenient freeway access and private parking add to the appeal. The home boasts quality beds and bedding, along with two private patios - one featuring a hot tub while the other offers fire chat seating. Moreover, there is a fully stocked kitchen. Enjoy!

Centrally located pet-friendly home.
Centrally located, this home is an ideal spot to explore San Diego from. It is only 10 minutes from the Airport and an easy 8 minute Uber from Downtown. It also provides all the amenities to feel right at home. The outdoor kitchen and sitting area are perfect for relaxing after a day spent exploring local attractions like the San Diego Zoo, Coronado and La Jolla beaches. Even out of the way attractions like Julian are a short one hour drive away.

Hillcrest #1 Cozy Private Balcony ZenGarden Garage
Heat up the cherry red kettle or a complementary coffee, sit back and enjoy, on your private balcony, overlooking the serene, Zen garden, while listening to the zen fountain. Zen Buddha, awaits your exit and every arrival to the property, whether retuning from the eclectic Hillcrest nightlife, or a scenic stroll through Balboa Park, with its many museums, gardens, fountains, restaurants and coffee shops.
Popular amenities for La Mesa smoking friendly rentals
Smoking friendly apartment rentals

Apartment with seaview

Private apartment 10 minutes from the consulate/airport/

Penthouse, Parking & Panoramic Views Little Italy

Resort style unique & tranquil vacation escape

#3- 2BR by the Beach Nice available monthly

SIE7E (Revolución) - “NEW” Condo

Condo Magico en Revolucion TJ

comfortable full apartment, 10 minutes from the border
Smoking friendly house rentals

San Diego SDSU House 20 mins to beach & downtown

Beso De Cielo 360 view, heated pool, 30 m to beach

spacious home & fresh eggs

Stylish 2BR Retreat, Fire Pit plus Outdoor Lounge

Spectacular Views | Amazing Escape Point Loma

La Mesa Outdoor Oasis w/ Heated Pool & Game Room

Coastal beauty, walk to pier.

Lovely Canyon-View Home Quiet, Private & Central
Smoking friendly condo rentals

Apartment on Revolución Excellent Location

REJUVENATE @Ocean111 >Available Now,Just Send Msg!

Artifact Inn - Escape in Vibrant Studio Top Spot!

Apartment 5 min Garitá de Otay-Airport-Consulate

Stylish/Modern/Gaslamp/Spacious 1BR/1BA

New King Bedroom Jacuzzis Billiards Parking Gym BB

Giraffe House

REJUVENATE @Ocean123 *Available Now,Just Send Msg*
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- Smoking-friendly rentals San Diego County
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- Rosarito Beach
- San Diego Convention Center E Ent
- SeaWorld San Diego
- Petco Park
- University of California-San Diego
- Oceanside City Beach
- San Diego Zoo Safari Park
- Ocean Front Walk
- Pacific Beach
- San Diego Zoo
- Coronado Beach
- Torrey Pines State Beach
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- Pechanga Resort Casino
- San Diego State University
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- Liberty Station
- Oceanside Harbor
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