
Smoking friendly vacation rentals in La Mesa
Find and book unique smoking friendly rentals on Airbnb
Quick stats about vacation rentals that are smoking-friendly in La Mesa

Total vacation rentals
Explore 10 vacation rentals in La Mesa

Nightly prices starting at
La Mesa vacation rentals start at G$10,447 GYD per night before taxes and fees

Verified guest reviews
Over 1,060 verified reviews to help you choose

Family-friendly vacation rentals
10 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 10 rentals that welcome pets

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
10 of La Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across La Mesa rentals

4.8 Average rating
La Mesa stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated smoking friendly rentals in La Mesa
Guests agree: these smoking friendly rentals are highly rated for location, cleanliness, and more.

Paradise View Staycation Q Bed, Sofa-bed *420 *
Welcome to our Spring Valley Retreat, escape to our charming granny house nestled in the heart of Spring Valley! Discover the tranquility of our 1 bedroom 1 bath sofa bed equipped kitchen, catch up work with high speed wi-fi in the design work place Unwind in our backyard oasis complete with inviting outdoor.furniture Conveniently located 25 minutes away from Downtown San Diego and Airport and short drive from pristine breaches. 5 minutes drive to grocery store and coffee shops/shopping center.

San Diego Mountain Retreat
3 bedroom 1 bathroom loft (2 separate sides) open concept guest house. Very peaceful East San Diego getaway. Enjoy beautiful ocean and Mountain Views during the day then relax in the jacuzzi with breath taking sunsets and the city lights at night. Best views in San Diego! Only 25 minutes from the SD airport and beaches. Minutes away from 2 local wineries and casinos. House sleeps 6 but you can invite guests up for the day for a fee. Event prices will be discussed per event. We live in main home

Private Entry | Crisp Sheets | Cozy Grotto Shower
Think of this like a hotel room or a minimalist studio. The entire unit is: - ONE compact room 6.5" x 11.5' - Bathroom - Private entrance There is no kitchen or living room. It's attached to my house. The room has a velvet couch that converts into a full sized bed. The bed is extremely comfy with its 2" topper. It will be ready as a bed upon arrival & is easy to convert into a couch. There is a desk, fridge/freezer, coffee machine, coffee, utensils, plates, bowls, washer/dryer & detergent.

Central San Diego! Your home away from home!
Guest house on property, outdoor smoking areas, outdoor gym. Art, fun, movie like experience with full cable, over 30 movie channels, DVD player, dinning table for eating or doing work. Extensive and secure business network. Cleaned, sanitized, checked after every visit. Full Kitchen, cooking utensils, Small 7.6 cu. ft. fridge, pots, pans and baking dishes for longer stays. Top notch Air conditioning and heating with plenty of extra blankets for your level of comfort. Your home away from home.

SDCannaBnB #2 *420 *parking *dog-friendly *hot tub
Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental! Our studio is newly remodeled with luxury ammenities. We proudly cater to the cannabis community and non-users alike. Our studio has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest. This ensures that every guest checks into a clean, fresh-smelling place that feels like home. Our studio is located in our quiet, fully fenced in backyard, close to San Diego's attractions

Guest Room with Beautiful Views
Welcome to our charming retreat nestled in San Diego. This private suite, attached to the main house, features its own bathroom, kitchenette, and a convenient private entrance with easy self-check-in. Just 10 minutes from Mission Beach, downtown San Diego, Balboa park, and SeaWorld. 5 min from Fashion Valley Mall, and only 2 minutes from the University of San Diego. You can either use the free parking space in front of the house or make use of the private driveway next to the house.

Mid-Century Style Family House with Spa
This home is the epitome of 1950’s luxury. A perfect family oasis, you won’t even want to leave the property. Beautiful Mt. Helix mid-century modern family home with incredible views, designed by architect of original Las Vegas Desert Inn situated on nearly an acre. Less than 20 minute drive to beaches/Zoo/Sea World/Downtown. With a swimming pool, jacuzzi, and AC. Surrounded by orange, lemon, pomegranate trees and herb garden. No loud parties please, this is a quiet community.

ROMANTIC AND SPACIOUS JACUZZI SUITE!
A completely private sanctuary with its own keyed entrance and no shared spaces. Enjoy breathtaking sunrises and sunsets from two private balconies, unwind in the jacuzzi, and relax in a suite designed for comfort. Plush mattresses and linens, a well-equipped kitchenette (microwave, Keurig coffee maker with coffee, mini-frig/freezer, toaster, two burner cooktop, kitchenware), and bathroom essentials including an iron/ironing board and hair dryer ensure a seamless, restful stay.

Upgraded Pt Loma Panoramic Views - 1 Bedroom Suite
Brand new full kitchen installed November 2025. Enjoy your home away from home and beautiful Pt Loma. With an expansive view of the gorgeous San Diego Bay & Shelter Island you can enjoy a comfortable space with luxury amenities. A spacious oasis to escape the hustle and bustle of the city, but close enough for a night out on the town. If you’d rather stay in and enjoy the views, relax on the patio, soak in the hot tub, or have a drink by the fire pit with your fur baby.

Fletcher Hills - modern 1 BR.Easy, no step access.
** 36 hours between check-ins. Thorough cleaning and sanitizing.. Four night minimum stay. Dogs ONLY are welcomed on a case by case basis. They must be house trained and are not permitted on any furniture. If you instant book, you must contact me about your pet within 24 hours. Smoking is permitted in the outside areas - patio, gazebo, yard. Easy freeway access helps any commute to downtown and area attractions. Having your own vehicle is the best way to get around..

San Diego's Finest: Private Hot Tub and Fire Chat
Newly renovated accommodations await with this centrally located 2-bedroom, 1-bath home close to popular attractions like beaches, the Zoo, Sea World, Bonita Golf Course, and Downtown San Diego. Convenient freeway access and private parking add to the appeal. The home boasts quality beds and bedding, along with two private patios - one featuring a hot tub while the other offers fire chat seating. Moreover, there is a fully stocked kitchen. Enjoy!

Centrally located pet-friendly home.
Centrally located, this home is an ideal spot to explore San Diego from. It is only 10 minutes from the Airport and an easy 8 minute Uber from Downtown. It also provides all the amenities to feel right at home. The outdoor kitchen and sitting area are perfect for relaxing after a day spent exploring local attractions like the San Diego Zoo, Coronado and La Jolla beaches. Even out of the way attractions like Julian are a short one hour drive away.
Popular amenities for La Mesa smoking friendly rentals
Smoking friendly apartment rentals

Apartment with seaview

Dpto. Priv. a 10 min del consulado/aeropuerto/

Penthouse, Parking & Panoramic Views Little Italy

Cozy tijuana aptmnt best neighborhood La Cacho

#3- 2BR by the Beach Nice available monthly

SIE7E (Revolución) - Condo “NEW”

Departamento privado con clima

cómodo depto. completo, 10 min. de la frontera
Smoking friendly house rentals

Hilltop Hideaway w/Jacuzzi, King Bed, close2 DTown

Terraza Aeropuerto 2

Renovated Residential Home in heart of San Diego

Hot Tub Getaway by the Coast

Trendy cottage with a private grassed courtyard.

Stunning San Diego Home w/Pool,Spa,Outdoor Oasis

Spectacular Views and Comfort-Book Now! King Bed!

Coastal beauty, walk to pier.
Smoking friendly condo rentals

Spacious private master bedroom/ living Room.

Large Group Luxury Condo! - (Se emiten Facturas).

Departamento sobre Revolución Excelente Ubicación

Artifact Inn - Escape in Vibrant Studio Top Spot!

Depto 5 min Garitá de Otay-Aeropuerto-Consulado

Stylish/Modern/Gaslamp/Spacious 1BR/1BA

Nuevo Recámara king Jacuzzis Billar Parking Gym BB

Giraffe House
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- Smoking-friendly rentals San Diego County
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- Rosarito Beach
- SeaWorld San Diego
- Coronado Beach
- University of California-San Diego
- LEGOLAND California
- San Diego Zoo Safari Park
- San Diego Zoo
- Petco Park
- San Diego Convention Center E Ent
- Balboa Park
- Tijuana Beach
- Pacific Beach
- Pechanga Resort Casino
- San Diego State University
- Torrey Pines State Beach
- Anza-Borrego Desert State Park
- Oceanside City Beach
- Mission Beach
- Ocean Front Walk
- La Misión Beach
- Moonlight State Beach
- Las Olas Resort & Spa
- Belmont Park
- Sesame Place San Diego





