
Family-friendly vacation rentals in La Mesa
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in La Mesa
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for La Mesa family-friendly rentals
Family-friendly home rentals with a hot tub

Pool Side Safari Cabin (On Backside of our Home)

Home at the Sanctuary

Former ManCave with Pool & Spa!

The Outside Inn at The Tipsy Goat Ranch

Nature Escape •Sauna•SoakTub•Views+Zoo pkg add-on

Zen Airstream Experience

Birdsong Suite | Family-friendly getaway

Loft Cabin •SoakTub•Cinema•View +Zoo pkg add-on
Family- and pet-friendly home rentals

Insta-worthy! 1 night/many nights, no min required

Retro Fun, S'mores & Smiles in Bettie Blue

Lemon Drop Cozy Studio

Fletcher Hills - modern 1 BR.Easy, no step access.

🤲🏼 Handmade hideaway Mt. Helix - AC/Laundry/Parking

Hacienda de Las Campanas

Private cozy cottage

Mountain top view getaway loft
Family-friendly home rentals with a pool

Lovely Guesthouse in garden setting

Mountain Retreat Ocean View-Great for Staycation

The BEST NEST Clean, peaceful, private, affordable

Sunny SD l Pool l BBQ l Pool Loungers l Sleeps 10

Bright and spacious home with views, pool & spa.

Charming Suite in Historic Home

Casita w/Private Pool, King Bed, Full Kitchen!

Upscale Resort House /Views, Saltwater Pool/Spa !
Quick stats about vacation rentals that are family-friendly in La Mesa
Total rentals
260 properties
Nightly prices starting at
G$10,458 GYD before taxes and fees
Total number of reviews
11K reviews
Pet-friendly rentals
110 properties allow pets
Rentals with a pool
80 properties have a pool
Rentals with dedicated workspaces
180 properties have a dedicated workspace
Destinations to explore
- Southern California Vacation rentals
- Los Angeles Vacation rentals
- Stanton Vacation rentals
- Las Vegas Vacation rentals
- San Diego Vacation rentals
- Channel Islands of California Vacation rentals
- Phoenix Vacation rentals
- Palm Springs Vacation rentals
- Scottsdale Vacation rentals
- San Fernando Valley Vacation rentals
- Las Vegas Strip Vacation rentals
- Henderson Vacation rentals
- Pet-friendly rentals La Mesa
- Rentals with an EV charger La Mesa
- Apartment rentals La Mesa
- Rentals with a fire pit La Mesa
- Rentals with outdoor seating La Mesa
- Villa rentals La Mesa
- Rentals with a washer and dryer La Mesa
- Rentals with beach access La Mesa
- Rentals with a hot tub La Mesa
- Fitness-friendly rentals La Mesa
- Smoking-friendly rentals La Mesa
- Rentals with a fireplace La Mesa
- Rentals with a beach view La Mesa
- Rentals with pools La Mesa
- Private suite rentals La Mesa
- Rentals with breakfast La Mesa
- House rentals La Mesa
- Rentals with a patio La Mesa
- Guesthouse rentals La Mesa
- Family-friendly rentals San Diego County
- Family-friendly rentals California
- Family-friendly rentals United States
- Rosarito Beach
- Oceanside City Beach
- Torrey Pines State Beach
- Pacific Beach
- Tijuana Beach
- SeaWorld San Diego
- University of California San Diego
- LEGOLAND California
- Coronado Beach
- San Diego Zoo Safari Park
- Balboa Park
- La Misión Beach
- Oceanside Harbor
- Pechanga Resort Casino
- Coronado Shores Beach
- Black's Beach
- Belmont Park
- Moonlight Beach
- Liberty Station
- Sesame Place San Diego
- Law Street Beach
- Torrey Pines Golf Course
- Santa Monica Beach
- Mission Beach