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Pet-friendly vacation rentals in Downtown San Diego

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in Downtown San Diego

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

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Superhost
A bright living area features a leather sofa and a rattan chair positioned beside a light-colored coffee table. Large windows allow natural light to fill the space, showcasing a minimalist decor style. A framed art piece and potted plants add a touch of greenery.
Townhouse in Little Italy
4.8 out of 5 average rating, 204 reviews

Contemporary, Fully Renovated Loft in Little Italy

Book this spectacular contemporary loft with 25 foot ceilings & views! The loft is in an area with a 9.8/10 walk score & known for having the best restaurants, bars &shops. The unit is newly renovated & meticulously designed with bright windows, contemporary high-end furnishings & an everyday spa inspired bathroom. Only steps from the waterfront, you decide if you want to enjoy cocktails & cuisine in the night scene or relax all day walking along the harbor. Free parking spot with access to all.

Top guest favorite
A private garden is illuminated at night, featuring various seating areas surrounded by lush greenery and colorful plants. Lanterns provide soft light, casting a warm glow on the outdoor space. A patterned rug and dark wooden furniture complete the serene atmosphere, inviting relaxation.
Guesthouse in San Diego
4.96 out of 5 average rating, 572 reviews

Romantic Private Garden Studio Near Downtown

A magical private garden surrounds a tiny studio (240 sq ft) with kitchenette in historic residential district, 10 blocks to East Village and Petco BallPark, near Gaslamp Quarter, and one mile to Convention Center and downtown. Easy access to freeways, very close to Balboa Park, San Diego Zoo, and Coronado Island. Airport and train station less than 15 min. We offer a safe, sweet, and contemplative getaway near the city, with WiFi but no TV. One pet OK only with prior approval. 420 friendly.

Top guest favorite
A spacious living area is characterized by high ceilings with exposed beams and large windows allowing natural light. A comfortable gray sofa, adorned with colorful cushions, is paired with a bright yellow accent chair. A modern coffee table and entertainment unit complete the inviting space.
Home in Little Italy
4.9 out of 5 average rating, 746 reviews

#1 LOCATION - Rare Luxury Home in Downtown

***THE BEST RATED RENTAL IN DOWNTOWN SAN DIEGO*** Location doesn't get better than this! Right in the heart of the lively Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. Just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & Zoo! All the frills: + Prime location! 98/100 Walker Score rating + Private parking + Private Sundeck & Backyard Stay at this modern luxury home for your next trip!

Superhost
A modern living area features a comfortable gray sofa adorned with a light throw. A round coffee table sits in front, flanked by green plants. The open kitchen displays stainless appliances and white cabinetry. Soft lighting is provided by pendant lights overhead, creating a welcoming ambiance.
Condo in Little Italy
4.83 out of 5 average rating, 138 reviews

NEW Stylish❤️ of Downtown Little Italy w Parking/AC

Located in the heart of Little Italy San Diego, this street level condo has been completely remodeled and re-imagined to make your stay unforgettable. Designed with the eye toward comfort and entertainment. *AC w/ independent temp control in each room *Voice Controlled Sound System, 4K TVs in every room *Beautiful bathroom w/ dual showers *Walk to coffee, yoga & gyms, dining, entertainment, shopping! 6 min to Zoo 5 min Airport 9 min to SeaWorld 6 min Petco Park 8 min to Coronado

Guest favorite
A bright living area features large floor-to-ceiling windows allowing ample natural light. A light wood coffee table is situated in front of a comfortable sofa adorned with decorative pillows. A large television stands on a modern console, with a potted plant adding a touch of greenery.
Home in Little Italy
4.84 out of 5 average rating, 218 reviews

Little Italy 2BR Loft Near Waterfront & Convention

Discover the heart of San Diego from our spacious loft in Little Italy, the culinary gem of downtown. Perfectly situated for both business and leisure travelers, you're steps away from the waterfront, convention center, and vibrant city life. Embrace the urban experience with convenience at your doorstep, including eclectic bars and restaurants. We provide a white noise machine and earplugs, though the lower floor offers a quieter retreat. Experience the best of city living!

Top guest favorite
The inviting entrance features a covered porch adorned with a vibrant yellow door. Succulents and greenery enhance the landscape, complemented by a palm tree nearby. The porch area includes seating, providing a welcoming atmosphere for relaxation.
Bungalow in Greater North Park
4.96 out of 5 average rating, 166 reviews

The Cozy Craftsman

Bright • Walkable • Charming 2BR Craftsman retreat in San Diego's University Heights neighborhood, perfectly located between Hillcrest and North Park.  Skylights and large windows fill the home with natural light, while the thoughtfully updated interior offers comfort and style.  Enjoy a private fenced yard with outdoor seating, and walk to restaurants, cafes, and a grocery store just two blocks away.  Perfect for couples, small groups, or business travelers exploring San Diego.

Guest favorite
Apartment in Downtown San Diego
4.88 out of 5 average rating, 112 reviews

Large Studio in Gaslamp, 3 bed w/ Parking included

Please Read Entire Listing Before Booking Noise WARNING Come stay at our mid-century modern loft inside a stylish Historic building. Located in the heart of Gaslamp Quarter. This 1100 sqft loft is perfect for a couples' vacation, friends night out, or traveling business people. The Gaslamp action is right downstairs. The loft is surrounded by restaurants, bars, nightclubs, coffee shops, and stores. Walking distance to the Convention Center, Petco Park. Sleeps up to 6.

Top guest favorite
A spacious penthouse room displays a high, triangular ceiling with modern fixtures. A comfortable bed is positioned prominently, complemented by large windows offering natural light. A sleek kitchen area features dark cabinetry and appliances, while a cozy seating area invites relaxation.
Condo in Bankers Hill - Park West
4.98 out of 5 average rating, 210 reviews

Dream Penthouse! The Most Amazing Bath & Views

Stunning Zen Penthouse with The Most Amazing Bathroom you have ever seen. Located right by Little Italy, Balboa Park, the Bay, the Convention Center, within walking distance to amazing restaurants, coffee shops, bars and within minutes of all San Diego Beaches and attractions. The Zen Penthouse has a total European feel to it, it's like being in London with amazing weather and the best part, the breathtaking views of the Skyline and unreal Sunsets!

Guest favorite
A spacious living area features a large gray sectional sofa positioned around a glass coffee table. Natural light filters through multiple windows, highlighting the hardwood floors and a wall-mounted TV opposite the seating. An open archway leads to the dining area in the background.
Townhouse in Little Italy
4.91 out of 5 average rating, 228 reviews

Sunny Good Vibes with View

NOTE PRIOR TO BOOKING: there is currently construction taking place in a separate detached rear building on the property week days only (7am-330pm). No construction on weekends; utilities, amenities, and services remain fully operational. Property listed at discounted rate as accommodation. 1100 sqft unit includes views, a private outdoor deck and walking distance or a short commute to San Diego's best attractions. Don’t delay, book today!

Guest favorite
A cozy living area features a blue couch adorned with decorative pillows against a stylish brick wall. Natural light streams through a large window, highlighting a round coffee table in front of a comfortable seating arrangement. A small plant adds a touch of greenery.
Condo in Downtown San Diego
4.93 out of 5 average rating, 427 reviews

Walk 2 Gaslamp & Petco; King bed, Parking/Patio!

Enjoy San Diego's vibrant Gaslamp Quarter! Set in the IDEAL location, this unique loft home is just STEPS to Convention Center & Petco Park, all the hot restaurants, shops & bars! Comfy King Bed upstairs opens to GARDEN PATIO with city view to relax! All necessities included, full kitchen w/ built in WINE fridge! FREE PARKING AVAILABLE Perfect for couples, solo adventurers, & business travelers. No parties or loud music allowed!

Guest favorite
Loft in Little Italy
4.82 out of 5 average rating, 377 reviews

Stylish Downtown Loft | Free Parking Near Bay

Tucked into the heart of Little Italy, this sun-drenched architectural loft is a calm, beautiful place to land in the middle of everything. Exposed brick, tall ceilings, and a chic open layout create a warm, inspiring retreat. Walk to top restaurants, cafes, bars, and Waterfront Park. Includes a cozy raised bed with ladder access, a full kitchen, one free onsite parking spot, and optional dog stay with $50 fee.

Guest favorite
Guest suite in Golden Hill
4.9 out of 5 average rating, 958 reviews

1 mile to Gaslamp—eScooters, Hot tub, Sauna

See more of our space and vibe by searching “The Birds & The Trees Vacations” online. California dreaming in our vintage citrus-themed space! This sweet little guest suite has everything you need: full kitchen, cozy bed, and thoughtful extras. Relax in the outdoor wellness oasis (infrared sauna, jacuzzi, cold plunge, fire pit), and take advantage of access to electric scooters and our ultimate beach kit.

Popular amenities for Downtown San Diego pet-friendly home rentals

When is the best time to visit Downtown San Diego?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$26,765 GYDG$28,229 GYDG$31,156 GYDG$26,556 GYDG$28,856 GYDG$28,019 GYDG$33,874 GYDG$29,065 GYDG$27,810 GYDG$28,856 GYDG$28,438 GYDG$30,320 GYD
Avg. temp15°C15°C16°C17°C18°C20°C21°C22°C22°C20°C17°C14°C

Quick stats about vacation rentals that are pet-friendly in Downtown San Diego

  • Total vacation rentals

    Explore 740 vacation rentals in Downtown San Diego

  • Nightly prices starting at

    Downtown San Diego vacation rentals start at G$10,455 GYD per night before taxes and fees

  • Verified guest reviews

    Over 39,990 verified reviews to help you choose

  • Family-friendly vacation rentals

    260 properties offer extra space & kid-friendly amenities

  • Vacation rentals with a pool

    230 properties feature pools

  • Rentals with dedicated workspaces

    540 properties have a dedicated workspace

  • Wi-Fi availability

    730 of Downtown San Diego vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Downtown San Diego rentals

  • 4.7 Average rating

    Downtown San Diego stays receive an average rating of 4.7 out of 5 from guests

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