
Vacation rentals in Downtown San Diego
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Top-rated vacation rentals in Downtown San Diego
Guests agree: these stays are highly rated for location, cleanliness, and more.

Vintage Spanish Revival Home - Balboa Park - Alcazar Court
• 1924 Spanish Revival Bungalows - Alcazar Court - Nestled in the heart of the city in historic Hillcrest - with cafes, bars, and shops • Fully equipped 1 bd 1 ba bungalows complement shady olive tree-lined patios - guests can enjoy coffee in the morning - a glass of wine in the afternoon. Enjoy the charm and tranquility of a bygone era and convenience of modern amenities, • Explore nearby Balboa Park, home to 16 museums and performing arts venues, as well as the world-famous San Diego Zoo.

NEW Luxury 3BR HOUSE❤️of DT Walk Petco w/Garage AC
Located in the heart of Downtown San Diego, this unique house has been completely remodeled and re-imagined to make your stay unforgettable. Designed with the eye toward comfort and entertainment. 7 min walk Petco Park/14 min walk to Convention Center/6 min to Zoo/9 min Airport/12 min to SeaWorld/9 min to Coronado *Stunning bathrooms w/ dual showers, tub, smart glass *Full Kitchen, AC Central *SONOS Sound System, 4K TVs every room *Walk to coffee, yoga & gyms, dining, entertainment, shopping!

Explore Little Italy from this Gorgeous Mini Villa
La Scala rises from the center of Villa Little Italy in the heart of San Diego’s most popular restaurant and entertainment district. Just one block from India Street, Farmer’s Market, and minutes from downtown, Balboa Park, airport, and harbor & beaches. This is a delightful neighborhood, steeped in local history and culture, and popular for dining and exploring. Little Italy Bungalows is perfect for couples, families, business travelers, convention-goers, single travelers and adventurers.

BEST LOCATION in all of Little Italy & downtown!
Location, location, location! Can't get any closer to the bustling Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. One of the only houses in all of downtown! This modern luxury home is just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & San Diego Zoo! All the frills: ++ Prime location! 98/100 Walker Score rating ++ High-speed internet, Netflix & smart TV ++ A/C ++ Super Host 5-star service

Calm Luxury Penthouse Getaway With Panoramic Views
Welcome to the most relaxing and luxurious penthouse condo in Little Italy! Featuring 2 expansive balconies with sweeping views, my condo sleeps 4-6 comfortably and is situated right in the heart of San Diego's most desirable neighborhood, Little Italy. Enjoy an area that is rich in exquisite cuisine, boutiques, patio cafés, exciting bars and local breweries. Area amenities nearby feature the famous San Diego Zoo, beautiful Balboa Park, Waterfront Park, the Convention Center and much more!

Kettner Row | Staycation-Featured Icon
Welcome to Kettner Row, a rare architectural masterpiece featured on Staycation Sports, an Emmy-winning show on the Destination Channel! Located in the heart of Little Italy—one of San Diego’s most desirable neighborhoods—and designed by renowned architect Jonathan Segal, FAIA. This detached row home is situated in the award-winning Little Italy Neighborhood Developers block (LIND). This modern home features dual master suites, a high-end designer kitchen, and luxurious spa bathrooms.

Waterfront Loft | 1BR | Little Italy | Downtown
The local neighborhood is highly walk-able and perched along the San Diego Bay in Little Italy. Little Italy is the most vibrant neighborhood in downtown San Diego with a main street that abounds with restaurants, boutiques, craft beer, and wine bars all at your doorstep. This is a very urban location which brings a lot of urban noise. The unit sits adjacent the train and trolley line in the urban core. No parking provided, Ideal for guests without a car.

Modern Private Loft • Walk to Petco
Stay steps from Petco Park in a thoughtfully designed two-story loft in the heart of downtown San Diego. Designed by award-winning architect Jonathan Segal, this modern space features high ceilings, a calm open layout, and a private balcony with city views. Enjoy a queen bed upstairs and a sofa bed in the living room, plus a full kitchen, washer/dryer, and easy self check-in. A more spacious, private, and relaxed alternative to typical downtown hotel stays.

Walk 2 Gaslamp & Petco; King bed, Parking/Patio!
Enjoy San Diego's vibrant Gaslamp Quarter! Set in the IDEAL location, this unique loft home is just STEPS to Convention Center & Petco Park, all the hot restaurants, shops & bars! Comfy King Bed upstairs opens to GARDEN PATIO with city view to relax! All necessities included, full kitchen w/ built in WINE fridge! FREE PARKING AVAILABLE Perfect for couples, solo adventurers, & business travelers. No parties or loud music allowed!

Stylish Downtown Loft | Free Parking Near Bay
Tucked into the heart of Little Italy, this sun-drenched architectural loft is a calm, beautiful place to land in the middle of everything. Exposed brick, tall ceilings, and a chic open layout create a warm, inspiring retreat. Walk to top restaurants, cafes, bars, and Waterfront Park. Includes a cozy raised bed with ladder access, a full kitchen, one free onsite parking spot, and optional dog stay with $50 fee.

At Mine | Spacious Suite in the Gaslamp Quarter
This meticulously renovated historical hotel suite, designed by Pininfarina, is located in Downtown San Diego’s vibrant Gaslamp Quarter, surrounded by restaurants and nightlife. It offers private, spacious accommodations for both business and leisure travelers, featuring a king bed, smart TV, central AC, and mini-fridge. Please note: an adjoining bar operates until midnight, and some noise is expected.

Stylish/Modern/Gaslamp/Spacious 1BR/1BA
Historic (800 sqft) building with 15ft ceilings. In the heart of downtown San Diego, located within the Gaslamp District. Perfect place to stay with your colleagues or friends. Minutes away from Petco Park, Little Italy, & Convention Center. Walking distance to a variety of restaurants, bars, nightlife, & coffee shops. Central location, close to the airport, SD Zoo, and Coronado beach.
Popular amenities for Downtown San Diego vacation rentals
Other great vacation rentals in Downtown San Diego

NEW Ultra Lux - Pool, Hot Tub, Mini Golf, Game Rm

Renovated Little Italy Home | Hot Tub & Pool Table

Stunning Villa by Little Italy & ConventionC w/Tub

Mountain View Retreat in Gated Estate (Hot Tub)

Beautiful 2-Story Loft in Heart of Little Italy

Downtown Dream 4

Kasa Little Italy | Studio, Rooftop Pool & Lux Gym

The Casa Amore!
When is the best time to visit Downtown San Diego?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$27,614 GYD | G$29,288 GYD | G$31,380 GYD | G$27,614 GYD | G$29,288 GYD | G$29,079 GYD | G$34,936 GYD | G$29,706 GYD | G$28,033 GYD | G$28,869 GYD | G$28,660 GYD | G$29,079 GYD |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Quick stats about vacation rentals in Downtown San Diego

Total vacation rentals
Explore 2,500 vacation rentals in Downtown San Diego

Verified guest reviews
Over 112,220 verified reviews to help you choose

Family-friendly vacation rentals
770 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 740 rentals that welcome pets

Vacation rentals with a pool
630 properties feature pools

Rentals with dedicated workspaces
1,410 properties have a dedicated workspace

Wi-Fi availability
2,460 of Downtown San Diego vacation rentals include wi-fi access

Popular amenities for guests
Guests love Gym, BBQ grill, and Laptop-friendly workspace across Downtown San Diego rentals

4.8 Average rating
Downtown San Diego stays are highly rated by guests—averaging 4.8 out of 5!
Destinations to explore
- Rentals with a fire pit Downtown San Diego
- Rentals with breakfast Downtown San Diego
- Pet-friendly rentals Downtown San Diego
- Hotel rooms Downtown San Diego
- Rentals with a fireplace Downtown San Diego
- Rentals with beach access Downtown San Diego
- Apartment rentals Downtown San Diego
- Loft rentals Downtown San Diego
- House rentals Downtown San Diego
- Rentals with an EV charger Downtown San Diego
- Family-friendly rentals Downtown San Diego
- Resort rentals Downtown San Diego
- Waterfront rentals Downtown San Diego
- Boutique hotels Downtown San Diego
- Rentals with outdoor seating Downtown San Diego
- Rentals with a sauna Downtown San Diego
- Condo rentals Downtown San Diego
- Fitness-friendly rentals Downtown San Diego
- Townhouse rentals Downtown San Diego
- Rentals with a hot tub Downtown San Diego
- Rentals with a home theater Downtown San Diego
- Rentals with a washer and dryer Downtown San Diego
- Hostel rentals Downtown San Diego
- Serviced apartment rentals Downtown San Diego
- Smoking-friendly rentals Downtown San Diego
- Rentals with pools Downtown San Diego
- Rentals with a patio Downtown San Diego
- Rosarito Beach
- San Diego Convention Center E Ent
- SeaWorld San Diego
- Petco Park
- University of California-San Diego
- Oceanside City Beach
- San Diego Zoo Safari Park
- Ocean Front Walk
- Pacific Beach
- Coronado Beach
- Torrey Pines State Beach
- Tijuana Beach
- San Diego Zoo
- Balboa Park
- San Diego State University
- Mission Beach
- La Misión Beach
- LEGOLAND California
- Moonlight State Beach
- Liberty Station
- Oceanside Harbor
- Belmont Park
- Sesame Place San Diego
- Black's Beach





