Vacation rentals in Downtown San Diego

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Top-rated vacation rentals in Downtown San Diego

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A hot tub is set in a cozy outdoor space, surrounded by wood decking and potted plants. Soft lighting hangs overhead, casting a gentle glow over the area. The entrance to the suite is visible in the background, enhancing the secluded atmosphere.
Guest suite in Greater North Park
5 out of 5 average rating, 108 reviews

Hidden Spa w/ Sauna and Hot Tub near Balboa Park

Welcome to your private spa in central San Diego! Relax and recharge in our peaceful guest suite, featuring: *sauna *steam shower *soaking bathtub *outdoor hot tub and private patio You’ll be in North Park, a walkable neighborhood with restaurants, coffee shops, and local boutiques. It's a short drive to Balboa Park, the San Diego Zoo, downtown, and the beaches. After a day of exploring, sink into the king-size bed. Perfect for romantic getaways, relaxing solo escapes, and wellness retreats.

Guest favorite
A spacious living area features large windows allowing ample natural light. A 85-inch 4K TV is mounted on the wall above a sleek entertainment unit. Comfortable seating includes a plush gray sofa and decorative pillows, with a coffee table at the center of the room.
Home in Downtown San Diego
4.92 out of 5 average rating, 201 reviews

NEW Luxury 3BR HOUSE❤️of DT Walk Petco w/Garage AC

Located in the heart of Downtown San Diego, this unique house has been completely remodeled and re-imagined to make your stay unforgettable. Designed with the eye toward comfort and entertainment. 7 min walk Petco Park/14 min walk to Convention Center/6 min to Zoo/9 min Airport/12 min to SeaWorld/9 min to Coronado *Stunning bathrooms w/ dual showers, tub, smart glass *Full Kitchen, AC Central *SONOS Sound System, 4K TVs every room *Walk to coffee, yoga & gyms, dining, entertainment, shopping!

Guest favorite
A modern apartment building features a combination of sleek architecture and natural wood accents. Large windows are framed by dark panels, allowing for ample natural light. Lush trees line the entrance, enhancing the urban landscape.
Apartment in Little Italy
4.87 out of 5 average rating, 189 reviews

Modern Inner City Pad w/ Patio | Walk Everywhere!

Enjoy everything Little Italy has to offer right on your doorstep from this bright, light and inviting apt. Open the floor-to-ceiling glass doors and let the sounds of the city in as you relax on the lounge and shaded patio. Cook in the modern kitchen, feel pampered in the luxe bathroom, then retire to the chic, king bedroom. Explore quaint streets, cafes, gelato shops, and charming trattorias just steps away then discover downtown, Balboa Park, & the Gaslamp Qtr, an easy 5/10 min drive away!

Guest favorite
A modern multi-unit building is displayed with a clearly marked loft entrance. The facade features a blend of light and dark materials, large windows, and distinctive architectural details. Street parking is visible alongside the structure, emphasizing convenient access to the location.
Townhouse in Little Italy
4.82 out of 5 average rating, 811 reviews

BEST LOCATION in all of Little Italy & downtown!

Location, location, location! Can't get any closer to the bustling Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. One of the only houses in all of downtown! This modern luxury home is just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & San Diego Zoo! All the frills: ++ Prime location! 98/100 Walker Score rating ++ High-speed internet, Netflix & smart TV ++ A/C ++ Super Host 5-star service

Top guest favorite
An expansive outdoor patio is showcased, featuring a comfortable sectional sofa with soft cushions and a stylish coffee table. Bi-folding doors connect to a modern kitchen area adorned with sleek cabinetry. The distant view reveals the San Diego coastline under a clear blue sky.
Apartment in Little Italy
4.94 out of 5 average rating, 240 reviews

Calm Luxury Penthouse Getaway With Panoramic Views

Welcome to the most relaxing and luxurious penthouse condo in Little Italy! Featuring 2 expansive balconies with sweeping views, my condo sleeps 4-6 comfortably and is situated right in the heart of San Diego's most desirable neighborhood, Little Italy. Enjoy an area that is rich in exquisite cuisine, boutiques, patio cafés, exciting bars and local breweries. Area amenities nearby feature the famous San Diego Zoo, beautiful Balboa Park, Waterfront Park, the Convention Center and much more!

Top guest favorite
Townhouse in Little Italy
4.95 out of 5 average rating, 150 reviews

Kettner Row | Staycation-Featured Icon

Welcome to Kettner Row, a rare architectural masterpiece featured on Staycation Sports, an Emmy-winning show on the Destination Channel! Located in the heart of Little Italy—one of San Diego’s most desirable neighborhoods—and designed by renowned architect Jonathan Segal, FAIA. This detached row home is situated in the award-winning Little Italy Neighborhood Developers block (LIND). This modern home features dual master suites, a high-end designer kitchen, and luxurious spa bathrooms.

Top guest favorite
A compact outdoor area features a wooden table with two matching stools, surrounded by greenery. A bottle of wine and two glasses are placed on the table, with a scenic view of palm trees and distant buildings visible in the background.
Loft in Little Italy
4.98 out of 5 average rating, 194 reviews

Waterfront Loft | 1BR | Little Italy | Downtown

The local neighborhood is highly walk-able and perched along the San Diego Bay in Little Italy. Little Italy is the most vibrant neighborhood in downtown San Diego with a main street that abounds with restaurants, boutiques, craft beer, and wine bars all at your doorstep. This is a very urban location which brings a lot of urban noise. The unit sits adjacent the train and trolley line in the urban core. No parking provided, Ideal for guests without a car.

Top guest favorite
Loft in Downtown San Diego
4.94 out of 5 average rating, 501 reviews

Modern Private Loft • Walk to Petco

Stay steps from Petco Park in a thoughtfully designed two-story loft in the heart of downtown San Diego. Designed by award-winning architect Jonathan Segal, this modern space features high ceilings, a calm open layout, and a private balcony with city views. Enjoy a queen bed upstairs and a sofa bed in the living room, plus a full kitchen, washer/dryer, and easy self check-in. A more spacious, private, and relaxed alternative to typical downtown hotel stays.

Superhost
Apartment in Little Italy
4.89 out of 5 average rating, 237 reviews

State & Fir (Little Italy Loft, Free Parking)

Ultra Minimal, Sunlit Bi-Level Loft In The Heart Of Little Italy—A Bright, Aesthetic Escape For Slow Mornings And Cozy Evenings. Enjoy Exposed Brick, High Ceilings, Beautiful Art, And An Airy Open Floor Plan. Step Outside To Trendy Cafés, Restaurants, Wine Bars, Farmers Markets, And Waterfront Park. Just Minutes To The Convention Center, Concerts, And The Trolley. Includes One Free On-Site Parking Spot And Free Laundry. Live Like A Local.

Guest favorite
Condo in Downtown San Diego
4.93 out of 5 average rating, 427 reviews

Walk 2 Gaslamp & Petco; King bed, Parking/Patio!

Enjoy San Diego's vibrant Gaslamp Quarter! Set in the IDEAL location, this unique loft home is just STEPS to Convention Center & Petco Park, all the hot restaurants, shops & bars! Comfy King Bed upstairs opens to GARDEN PATIO with city view to relax! All necessities included, full kitchen w/ built in WINE fridge! FREE PARKING AVAILABLE Perfect for couples, solo adventurers, & business travelers. No parties or loud music allowed!

Superhost
A spacious room features exposed brick walls and large windows allowing natural light. A comfortable bed is positioned in the foreground, with a seating area and smart TV visible in the background. Modern design elements, including a lounge chair and stylish decor, create an inviting ambiance.
Apartment in Downtown San Diego
4.88 out of 5 average rating, 1,828 reviews

At Mine | Spacious Suite in the Gaslamp Quarter

This meticulously renovated historical hotel suite, designed by Pininfarina, is located in Downtown San Diego’s vibrant Gaslamp Quarter, surrounded by restaurants and nightlife. It offers private, spacious accommodations for both business and leisure travelers, featuring a king bed, smart TV, central AC, and mini-fridge. Please note: an adjoining bar operates until midnight, and some noise is expected.

Guest favorite
An aerial view of a spacious living area features a modern gray sectional sofa with orange cushions. A large television is mounted on a concrete wall. A round dining table with white chairs sits adjacent to a glass coffee table, illuminated by natural light from large windows.
Condo in Downtown San Diego
4.97 out of 5 average rating, 167 reviews

King Size Luxury Loft Petco-Park-Downtown SD

This gorgeous loft is situated in the heart of Downtown San Diego. Adjacent to East Village-Petco Park. This ground-level unit offers easy access and central location within walking distance to restaurants, bars, cafes, and the convention center. Because the property is located in a lively downtown area at street level, guests may occasionally experience typical city Noice or activity

Popular amenities for Downtown San Diego vacation rentals

When is the best time to visit Downtown San Diego?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$27,614 GYDG$29,287 GYDG$31,379 GYDG$27,614 GYDG$29,287 GYDG$29,078 GYDG$34,935 GYDG$29,705 GYDG$28,032 GYDG$28,869 GYDG$28,659 GYDG$29,078 GYD
Avg. temp15°C15°C16°C17°C18°C20°C21°C22°C22°C20°C17°C14°C

Quick stats about vacation rentals in Downtown San Diego

  • Total vacation rentals

    Explore 2,500 vacation rentals in Downtown San Diego

  • Verified guest reviews

    Over 112,220 verified reviews to help you choose

  • Family-friendly vacation rentals

    770 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 740 rentals that welcome pets

  • Vacation rentals with a pool

    630 properties feature pools

  • Rentals with dedicated workspaces

    1,410 properties have a dedicated workspace

  • Wi-Fi availability

    2,460 of Downtown San Diego vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Gym, BBQ grill, and Laptop-friendly workspace across Downtown San Diego rentals

  • 4.8 Average rating

    Downtown San Diego stays are highly rated by guests—averaging 4.8 out of 5!

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