Vacation rentals in Downtown San Diego

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Top-rated vacation rentals in Downtown San Diego

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost
A bright living area features a leather sofa and a rattan chair positioned beside a light-colored coffee table. Large windows allow natural light to fill the space, showcasing a minimalist decor style. A framed art piece and potted plants add a touch of greenery.
Townhouse in Little Italy
4.8 out of 5 average rating, 202 reviews

Contemporary, Fully Renovated Loft in Little Italy

Book this spectacular contemporary loft with 25 foot ceilings & views! The loft is in an area with a 9.8/10 walk score & known for having the best restaurants, bars &shops. The unit is newly renovated & meticulously designed with bright windows, contemporary high-end furnishings & an everyday spa inspired bathroom. Only steps from the waterfront, you decide if you want to enjoy cocktails & cuisine in the night scene or relax all day walking along the harbor. Free parking spot with access to all.

Top guest favorite
A sunlit living area features two comfortable armchairs facing a glass coffee table with books and magazines. Large windows are adorned with light curtains, and a decorative lamp adds warmth. A dining table with chairs is positioned nearby, creating a cozy gathering space.
Bungalow in Hillcrest
4.97 out of 5 average rating, 425 reviews

Vintage Spanish Revival Home - Balboa Park - Alcazar Court

• 1924 Spanish Revival Bungalows - Alcazar Court - Nestled in the heart of the city in historic Hillcrest - with cafes, bars, and shops • Fully equipped 1 bd 1 ba bungalows complement shady olive tree-lined patios - guests can enjoy coffee in the morning - a glass of wine in the afternoon. Enjoy the charm and tranquility of a bygone era and convenience of modern amenities, • Explore nearby Balboa Park, home to 16 museums and performing arts venues, as well as the world-famous San Diego Zoo.

Guest favorite
A modern multi-unit building is displayed with a clearly marked loft entrance. The facade features a blend of light and dark materials, large windows, and distinctive architectural details. Street parking is visible alongside the structure, emphasizing convenient access to the location.
Townhouse in Little Italy
4.83 out of 5 average rating, 808 reviews

BEST LOCATION in all of Little Italy & downtown!

Location, location, location! Can't get any closer to the bustling Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. One of the only houses in all of downtown! This modern luxury home is just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & San Diego Zoo! All the frills: ++ Prime location! 98/100 Walker Score rating ++ High-speed internet, Netflix & smart TV ++ A/C ++ Super Host 5-star service

Top guest favorite
Apartment in Little Italy
4.95 out of 5 average rating, 147 reviews

Modern Central Gem w/ Patio | Steps to All!

Discover the heart of Little Italy with our inviting apartment. Bright and airy, the space features floor-to-ceiling glass doors that open to a shaded patio, letting the city sound in as you unwind on the lounge. Prepare meals in the modern kitchen and then retreat to the stylish, chic king bedroom. Explore nearby streets filled with cafes, gelato shops, and trattorias. Downtown, Balboa Park, and the Gaslamp Quarter are just a short 5/10-minute drive away. Your ideal urban getaway awaits!

Guest favorite
The exterior of Villa Little Italy is showcased, featuring a modern Art Deco design with smooth white walls and circular windows. A wooden fence secures the patio area, while potted plants add greenery. The building is positioned at an angle, capturing the inviting entrance.
Bungalow in Little Italy
4.93 out of 5 average rating, 394 reviews

Gorgeous 2Bd Corner Bungalow in Little Italy

Little Italy Bungalows are located in the heart of San Diego’s most popular restaurant and entertainment district, Little Italy. Just one block from India Street, Farmer’s Market, and minutes from downtown, Balboa Park, airport, and harbor & beaches. This is a delightful neighborhood, steeped in local history and culture, and popular for dining and exploring. Little Italy Bungalows is perfect for couples, families, business travelers, convention-goers, single travelers and adventurers.

Top guest favorite
The living room features soaring ceilings and a wall of windows, allowing ample natural light to illuminate the space. Comfortable seating arrangements are complemented by modern art pieces on the walls. A sleek fireplace and stylish furniture create a welcoming ambiance, framed by elegant decor.
Townhouse in Little Italy
4.95 out of 5 average rating, 146 reviews

Kettner Row | Staycation-Featured Icon

Welcome to Kettner Row, a rare architectural masterpiece featured on Staycation Sports, an Emmy-winning show on the Destination Channel! Located in the heart of Little Italy—one of San Diego’s most desirable neighborhoods—and designed by renowned architect Jonathan Segal, FAIA. This detached row home is situated in the award-winning Little Italy Neighborhood Developers block (LIND). This modern home features dual master suites, a high-end designer kitchen, and luxurious spa bathrooms.

Superhost
The open kitchen features a stone countertop and white cabinetry, complemented by three bar stools. Modern stainless appliances are present, with pendant lighting hanging above. A view into the connected powder room is visible through a sliding door.
Condo in Little Italy
4.82 out of 5 average rating, 137 reviews

NEW Stylish❤️ of Downtown Little Italy w Parking/AC

Located in the heart of Little Italy San Diego, this street level condo has been completely remodeled and re-imagined to make your stay unforgettable. Designed with the eye toward comfort and entertainment. *AC w/ independent temp control in each room *Voice Controlled Sound System, 4K TVs in every room *Beautiful bathroom w/ dual showers *Walk to coffee, yoga & gyms, dining, entertainment, shopping! 6 min to Zoo 5 min Airport 9 min to SeaWorld 6 min Petco Park 8 min to Coronado

Top guest favorite
Loft in Downtown San Diego
4.94 out of 5 average rating, 498 reviews

Modern Private Loft • Walk to Petco

Stay steps from Petco Park in a thoughtfully designed two-story loft in the heart of downtown San Diego. Designed by award-winning architect Jonathan Segal, this modern space features high ceilings, a calm open layout, and a private balcony with city views. Enjoy a queen bed upstairs and a sofa bed in the living room, plus a full kitchen, washer/dryer, and easy self check-in. A more spacious, private, and relaxed alternative to typical downtown hotel stays.

Superhost
Apartment in Little Italy
4.89 out of 5 average rating, 233 reviews

State & Fir (Little Italy Loft, Free Parking)

Ultra Minimal, Sunlit Bi-Level Loft In The Heart Of Little Italy—A Bright, Aesthetic Escape For Slow Mornings And Cozy Evenings. Enjoy Exposed Brick, High Ceilings, Beautiful Art, And An Airy Open Floor Plan. Step Outside To Trendy Cafés, Restaurants, Wine Bars, Farmers Markets, And Waterfront Park. Just Minutes To The Convention Center, Concerts, And The Trolley. Includes One Free On-Site Parking Spot And Free Laundry. Live Like A Local.

Guest favorite
A modern living space features a full kitchen with stainless steel appliances and a spacious island. Comfortable seating is arranged around a coffee table, of which a large window allows ample natural light to illuminate the room. A stairway leads to the upper level.
Condo in Downtown San Diego
4.93 out of 5 average rating, 426 reviews

Walk 2 Gaslamp & Petco; King bed, Parking/Patio!

Enjoy San Diego's vibrant Gaslamp Quarter! Set in the IDEAL location, this unique loft home is just STEPS to Convention Center & Petco Park, all the hot restaurants, shops & bars! Comfy King Bed upstairs opens to GARDEN PATIO with city view to relax! All necessities included, full kitchen w/ built in WINE fridge! FREE PARKING AVAILABLE Perfect for couples, solo adventurers, & business travelers. No parties or loud music allowed!

Guest favorite
A spacious room features exposed brick walls and large windows allowing natural light. A comfortable bed is positioned in the foreground, with a seating area and smart TV visible in the background. Modern design elements, including a lounge chair and stylish decor, create an inviting ambiance.
Apartment in Downtown San Diego
4.88 out of 5 average rating, 1,806 reviews

At Mine | Spacious Suite in the Gaslamp Quarter

This meticulously renovated historical hotel suite, designed by Pininfarina, is located in Downtown San Diego’s vibrant Gaslamp Quarter, surrounded by restaurants and nightlife. It offers private, spacious accommodations for both business and leisure travelers, featuring a king bed, smart TV, central AC, and mini-fridge. Please note: an adjoining bar operates until midnight, and some noise is expected.

Top guest favorite
Apartment in Downtown San Diego
4.94 out of 5 average rating, 47 reviews

Stunning Views & 1 min to Petco Park 1BD Apartment

Located 1-minute walk from Petco Park, Convention Center, Gaslamp. Only minutes to Little Italy, Seaport Village, the Airport, Coronado Island, Balboa Park, and the Zoo. This location is super walkable and convenient for public transportation. Has stunning views of the bay and Petco Park events right from the balcony and from the bedroom. The place is fully equipped with everything you need!

Popular amenities for Downtown San Diego vacation rentals

When is the best time to visit Downtown San Diego?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$27,612 GYDG$29,285 GYDG$31,377 GYDG$27,612 GYDG$29,285 GYDG$29,076 GYDG$34,933 GYDG$29,704 GYDG$28,030 GYDG$28,867 GYDG$28,658 GYDG$29,076 GYD
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Quick stats about vacation rentals in Downtown San Diego

  • Total vacation rentals

    Explore 2,500 vacation rentals in Downtown San Diego

  • Verified guest reviews

    Over 112,220 verified reviews to help you choose

  • Family-friendly vacation rentals

    770 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 740 rentals that welcome pets

  • Vacation rentals with a pool

    630 properties feature pools

  • Rentals with dedicated workspaces

    1,410 properties have a dedicated workspace

  • Wi-Fi availability

    2,460 of Downtown San Diego vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Gym, BBQ grill, and Laptop-friendly workspace across Downtown San Diego rentals

  • 4.8 Average rating

    Downtown San Diego stays are highly rated by guests—averaging 4.8 out of 5!

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