
House vacation rentals in Downtown San Diego
Find and book unique houses on Airbnb
Quick stats about house rentals in Downtown San Diego

Total vacation rentals
Explore 170 vacation rentals in Downtown San Diego

Nightly prices starting at
Downtown San Diego vacation rentals start at G$12,550 GYD per night before taxes and fees

Verified guest reviews
Over 14,860 verified reviews to help you choose

Family-friendly vacation rentals
110 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 60 rentals that welcome pets

Rentals with dedicated workspaces
80 properties have a dedicated workspace

Wi-Fi availability
160 of Downtown San Diego vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Downtown San Diego rentals

4.8 Average rating
Downtown San Diego stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated house rentals in Downtown San Diego
Guests agree: these houses are highly rated for location, cleanliness, and more.

Walk to Balboa Park and Hillcrest from an Immaculate Home
Take a stroll through the park, then unwind with a leisurely dinner under the festoon lights. Classic crown molding, hardwood floors, and pared-back tones of gray and taupe create an air of calm at this elegant haven spread out over 1500 square feet. You will find the space charming & spacious with over 1500 sq. feet. This single level property is the lower level of a historic duplex. Hardwood floors, crown molding, gas fireplace and laundry room. Street parking is usually readily available. This A+ location of Banker's Hill is NOT impacted by air plane noise. Enjoy the entire lower level duplex and use of the back yard with patio set for dining. Please note the upper tenant may also want to use this space so this area could be shared. We would love to greet you but are also fine with allowing you to access with a code on the front door. We live nearby and are happy to make suggestions for dining or things to do. Located near numerous restaurants, and Balboa Park, Hillcrest, the zoo, Downtown, Little Italy, and the Convention Center are all within 10 minutes. Be at the beach in less than 15 minutes. The bus line runs up First Ave for easy access to Downtown and Uptown. Near trolley and train station. We are within 10 minutes to the San Diego International Airport and a quick Uber ride to Downtown, Little Italy. Walk to the heart of Hillcrest, Balboa Park and the Zoo. Be at the beach in less then 15 minutes. Central location near the I-5, I-163 & I-8. Because of the hardwood floors, you will hear the footsteps above. The kitchen is well stocked if your a cook and we have an area where you can set up your laptop. wireless available and 3 smart TV's for your enjoyment. Small market less than 1 block away.
4.95 out of 5 average rating, 370 reviews
1stResorts.com WATERVIEW FAMILY VILLA HOT TUB YARD
Brand New FAMILY Villa: Full kitchen, Private back deck off living space & Private yard! Private Hot tub/fire pit & outdoor furniture! Near Sea World, the Zoo, other great activities for children & great restaurants! Near Little Italy, Balboa Park, Liberty Station, Seaport Village! 2 bedrooms w/king beds, 1 full bathroom w/shower & double sinks. Powder room, free private washer/dryer. Private Barbecue grill. Beach towels, queen pullout sofa bed. Back deck connected to living area & private yard!
4.94 out of 5 average rating, 103 reviews
Admire Harbor Views from the Porch at a City Gem
Unwind in a cozy colorful casita in this light-filled 1920s Spanish bungalow decorated with Mexican folklorico. Take a walk into Little Italy for dinner. Or to a show at the Old Globe.What’s best, is how close you are to so much, all without needing a car. A very small single car garage is provided, think compact car. Street parking is free but challenging at times. The house is located directly below the incoming flight path. You are encouraged to read the reviews regarding this.Ideal for four.
4.95 out of 5 average rating, 512 reviews
Little Italy Historical
This AirBNB residence is a recently fully renovated historical property in San Diego’s Little Italy community. Many say it’s one of the finest. It is only 3 short blocks from Little Italy’s vibrant India Street and its many restaurants, bars, cafes, and shops, and four from the Trolley. It’s also a short drive to San Diego’s beaches and attractions. The AirBNB unit is a ground floor private one bed/one bath suite with a living room and its own entrances. Pics and descriptions are enclosed.
4.98 out of 5 average rating, 115 reviews
NEW Luxury 3BR HOUSEof DT Walk Petco w/Garage AC
Located in the heart of Downtown San Diego, this unique house has been completely remodeled and re-imagined to make your stay unforgettable. Designed with the eye toward comfort and entertainment. 7 min walk Petco Park/14 min walk to Convention Center/6 min to Zoo/9 min Airport/12 min to SeaWorld/9 min to Coronado *Stunning bathrooms w/ dual showers, tub, smart glass *Full Kitchen, AC Central *SONOS Sound System, 4K TVs every room *Walk to coffee, yoga & gyms, dining, entertainment, shopping!
4.92 out of 5 average rating, 213 reviews
Modern Surf Themed Home - Heart of Gaslamp
Step into a modern surf-themed retreat in the vibrant heart of San Diego's Gaslamp Quarter. Perfectly blending laid-back coastal vibes with sleek, urban style, this one-of-a-kind home is designed to be your getaway oasis in the middle of all the action. 7 actual beds no air mattresses or sofa-beds. This is the only 4-bedroom 4-bath for rent in all downtown San Diego. It is close to Convention Center, Petco Park, and Nightlife. This is not a party house. Person booking home must be over 25.
4.97 out of 5 average rating, 157 reviews
Bayview Paradise
Known as the Huguette House, this luxury private single-family two bedrooms two bathrooms home in La Playa the heart of Point Loma, San Diego offers 180-degree panoramic views of the world-famous San Diego Bay and Downtown Skyline. views of the San Diego bay, marina, and Coronado Island during the day and spectacular views of the Downtown San Diego skyline at night, fully equipped kitchen, and laundry room, 2 bedroom suites with queen beds .2 luxury bathrooms, HDTV, computer desk and WFI
4.99 out of 5 average rating, 155 reviews
EpicViews | 3-Stories with Rooftop | Cortez Hill
📍 Unbeatable Central Location! Welcome to Casa Cortez Hill! This charming 3-story home features 3 bedrooms, 2 baths, and a private 4th-story rooftop deck with firepit. At 1,510 sq ft, it comfortably sleeps up to 8 guests. Centrally located—walk to Little Italy, Gaslamp, and Petco Park. Just few miles from the airport and minutes to the beach. Enjoy San Diego’s best dining, nightlife, and coastal vibes. Casa Cortez Hill is your home base for all things San Diego. We can't wait to host you!
4.99 out of 5 average rating, 150 reviews
#1 LOCATION - Rare Luxury Home in Downtown
***THE BEST RATED RENTAL IN DOWNTOWN SAN DIEGO*** Location doesn't get better than this! Right in the heart of the lively Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. Just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & Zoo! All the frills: + Prime location! 98/100 Walker Score rating + Private parking + Private Sundeck & Backyard Stay at this modern luxury home for your next trip!
4.9 out of 5 average rating, 767 reviews
Pool Oasis in Central Hillcrest by Park/Zoo
The enormous infinite edge pool floats above the jungle floor. Perched on a private canyon, this modern house is conveniently located in the heart of Hillcrest, walking distance to restaurants, bars, Balboa Park, the San Diego Zoo. Private paradise in walking neighborhood! Multiple private work spaces with treetop views. Cinema room with surround sound! NOTE: Not suitable for young children (heights, noise restrictions, breakables). NO PETS! NO PARTIES! (STRICT!). TOT# 641946.
4.92 out of 5 average rating, 185 reviews
Little Italy 2BR Loft Near Waterfront & Convention
Discover the heart of San Diego from our spacious loft in Little Italy, the culinary gem of downtown. Perfectly situated for both business and leisure travelers, you're steps away from the waterfront, convention center, and vibrant city life. Embrace the urban experience with convenience at your doorstep, including eclectic bars and restaurants. We provide a white noise machine and earplugs, though the lower floor offers a quieter retreat. Experience the best of city living!
4.83 out of 5 average rating, 228 reviews
Downtown View - 2 Story House Next to Little Italy
Two story house with 2 living rooms; 3 blocks to Little Italy restaurants, bars, & shops. Near Balboa Park, San Diego Zoo, Gaslamp, Waterfront Park & the Harbor. Museums, restaurants, theaters & nature are all nearby. Located in historic Bankers Hill, next to Interstate 5, near the airport and city center. With 2 living rooms, my house is perfect for travelers needing separate space. One parking spot is available. Extra large vehicles will have to park on the street.
4.98 out of 5 average rating, 323 reviewsPopular amenities for Downtown San Diego house rentals
House rentals with a pool

Lionhead - Private Boutique Home
4.93 out of 5 average rating, 293 reviews
1 bedroom, 1 bath /Hillcrest/San Diego Zoo/Balboa
4.99 out of 5 average rating, 192 reviews
Midcentury Lux 4BR home w Pool/Spa/Cabana/Firepit
5.0 out of 5 average rating, 303 reviews
Your Modern Lux Pool Resort in the Heart of SD
4.9 out of 5 average rating, 189 reviews
Resort Style Living with Pool, Spa, and Bay Views!
4.97 out of 5 average rating, 317 reviews
Cozy University Heights Cottage
4.87 out of 5 average rating, 126 reviews
Designer Luxury Rental With Pool
4.94 out of 5 average rating, 151 reviews
Family Oasis w/ Heated Pool
4.98 out of 5 average rating, 125 reviewsWeekly house rentals

Bankers Hill House | Bay & Downtown Views+Fire Pit
4.83 out of 5 average rating, 153 reviews
Beautiful New 2BR/2.5BA Coastal Home In Point Loma
4.97 out of 5 average rating, 309 reviews
Modern ❤️ of South Park, SD skyline, private patio
4.94 out of 5 average rating, 335 reviews
Upscale 3 Bed Oasis | Fire Pit, BBQ | Downtown SD
4.96 out of 5 average rating, 190 reviews
Designer Unit w/FirePit-Petco Park, Zoo, Downtown
4.97 out of 5 average rating, 125 reviews
Golden Hill Tree House
4.99 out of 5 average rating, 437 reviews
Historic Post Office loft 4 Bed + firepit Near Zoo
4.88 out of 5 average rating, 163 reviews
Elegant 2 bedroom + loft in Hillcrest.
4.9 out of 5 average rating, 200 reviewsPrivate house rentals

1920s Historic Gem | Private Oasis & Sunlit Court
4.99 out of 5 average rating, 134 reviews
Top 1% | Hot Tub Oasis | Walkable North Park
5.0 out of 5 average rating, 193 reviews
South Park Spanish Stunner Renovated & Central
4.88 out of 5 average rating, 166 reviews
Stanton Residence - Downtown Victorian Classic
4.99 out of 5 average rating, 138 reviews
Stunning Mansion by The ConventionC & LittleItaly
4.89 out of 5 average rating, 148 reviews
Hillcrest 2 bed 2 en-suite baths garage zen garden
4.98 out of 5 average rating, 437 reviews
Private Canyon Sanctuary
4.99 out of 5 average rating, 361 reviewsWalk to Petco Park, Downtown, Gaslamp w/ garage!
4.84 out of 5 average rating, 353 reviewsWhen is the best time to visit Downtown San Diego?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$42,044 GYD | G$44,972 GYD | G$48,947 GYD | G$50,411 GYD | G$49,365 GYD | G$54,803 GYD | G$58,359 GYD | G$50,620 GYD | G$45,809 GYD | G$44,972 GYD | G$44,763 GYD | G$49,574 GYD |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Destinations to explore
- Townhouse rentals Downtown San Diego
- Rentals with a sauna Downtown San Diego
- Boutique hotels Downtown San Diego
- Resort rentals Downtown San Diego
- Rentals with breakfast Downtown San Diego
- Rentals with beach access Downtown San Diego
- Rentals with pools Downtown San Diego
- Hostel rentals Downtown San Diego
- Family-friendly rentals Downtown San Diego
- Waterfront rentals Downtown San Diego
- Rentals with a hot tub Downtown San Diego
- Hotel rooms Downtown San Diego
- Apartment rentals Downtown San Diego
- Loft rentals Downtown San Diego
- Pet-friendly rentals Downtown San Diego
- Condo rentals Downtown San Diego
- Serviced apartment rentals Downtown San Diego
- House rentals San Diego
- House rentals San Diego County
- House rentals California
- House rentals United States
- SeaWorld San Diego
- Rosarito Beach
- Coronado Beach
- LEGOLAND California
- University of California-San Diego
- Petco Park
- San Diego Zoo
- San Diego Convention Center E Ent
- San Diego Zoo Safari Park
- Pacific Beach
- San Diego State University
- Balboa Park
- Tijuana Beach
- Torrey Pines State Beach
- Mission Beach
- Las Olas Resort & Spa
- Ocean Front Walk
- Oceanside City Beach
- La Misión Beach
- Moonlight State Beach
- Belmont Park
- Sesame Place San Diego
- South Mission Beach, San Diego
- Liberty Station





