
House vacation rentals in Downtown San Diego
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Quick stats about house rentals in Downtown San Diego

Total vacation rentals
Explore 170 vacation rentals in Downtown San Diego

Nightly prices starting at
Downtown San Diego vacation rentals start at G$12,552 GYD per night before taxes and fees

Verified guest reviews
Over 14,860 verified reviews to help you choose

Family-friendly vacation rentals
110 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 60 rentals that welcome pets

Rentals with dedicated workspaces
80 properties have a dedicated workspace

Wi-Fi availability
160 of Downtown San Diego vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Downtown San Diego rentals

4.8 Average rating
Downtown San Diego stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated house rentals in Downtown San Diego
Guests agree: these houses are highly rated for location, cleanliness, and more.

Walk to Balboa Park and Hillcrest from an Immaculate Home
Take a stroll through the park, then unwind with a leisurely dinner under the festoon lights. Classic crown molding, hardwood floors, and pared-back tones of gray and taupe create an air of calm at this elegant haven spread out over 1500 square feet. You will find the space charming & spacious with over 1500 sq. feet. This single level property is the lower level of a historic duplex. Hardwood floors, crown molding, gas fireplace and laundry room. Street parking is usually readily available. This A+ location of Banker's Hill is NOT impacted by air plane noise. Enjoy the entire lower level duplex and use of the back yard with patio set for dining. Please note the upper tenant may also want to use this space so this area could be shared. We would love to greet you but are also fine with allowing you to access with a code on the front door. We live nearby and are happy to make suggestions for dining or things to do. Located near numerous restaurants, and Balboa Park, Hillcrest, the zoo, Downtown, Little Italy, and the Convention Center are all within 10 minutes. Be at the beach in less than 15 minutes. The bus line runs up First Ave for easy access to Downtown and Uptown. Near trolley and train station. We are within 10 minutes to the San Diego International Airport and a quick Uber ride to Downtown, Little Italy. Walk to the heart of Hillcrest, Balboa Park and the Zoo. Be at the beach in less then 15 minutes. Central location near the I-5, I-163 & I-8. Because of the hardwood floors, you will hear the footsteps above. The kitchen is well stocked if your a cook and we have an area where you can set up your laptop. wireless available and 3 smart TV's for your enjoyment. Small market less than 1 block away.

Admire Harbor Views from the Porch at a City Gem
Unwind in a cozy colorful casita in this light-filled 1920s Spanish bungalow decorated with Mexican folklorico. Take a walk into Little Italy for dinner. Or to a show at the Old Globe.What’s best, is how close you are to so much, all without needing a car. A very small single car garage is provided, think compact car. Street parking is free but challenging at times. The house is located directly below the incoming flight path. You are encouraged to read the reviews regarding this.Ideal for four.

NEW Luxury 3BR HOUSE❤️of DT Walk Petco w/Garage AC
Located in the heart of Downtown San Diego, this unique house has been completely remodeled and re-imagined to make your stay unforgettable. Designed with the eye toward comfort and entertainment. 7 min walk Petco Park/14 min walk to Convention Center/6 min to Zoo/9 min Airport/12 min to SeaWorld/9 min to Coronado *Stunning bathrooms w/ dual showers, tub, smart glass *Full Kitchen, AC Central *SONOS Sound System, 4K TVs every room *Walk to coffee, yoga & gyms, dining, entertainment, shopping!

#1 LOCATION - Rare Luxury Home in Downtown
***THE BEST RATED RENTAL IN DOWNTOWN SAN DIEGO*** Location doesn't get better than this! Right in the heart of the lively Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. Just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & Zoo! All the frills: + Prime location! 98/100 Walker Score rating + Private parking + Private Sundeck & Backyard Stay at this modern luxury home for your next trip!

Condé Nast Villa | Speakeasy · Hot Tub · Sleeps 10
🏡 1,131 sq ft of curated interior space 🍳 Fully stocked kitchen 🛏️ 3 Queen Beds, 2 Twin Beds & 2 Twin Rollaway Beds 📺 Outdoor Lounge Area w/TV 🛁 Insta-worthy cast iron clawfoot hot tub — outdoors 🧺 Complimentary Washer & Dryer 🔒 Fully gated backyard 🚗 Private Parking (2 spots) 🏙️ 7 min to downtown 🦁 8 min to Zoo & Balboa Park ✈️ 12 min to airport & beach —>Want to enjoy the speakeasy? Just a heads-up—it’s not included in the base rate, but can be added for an additional fee!

Little Italy 2BR Loft Near Waterfront & Convention
Discover the heart of San Diego from our spacious loft in Little Italy, the culinary gem of downtown. Perfectly situated for both business and leisure travelers, you're steps away from the waterfront, convention center, and vibrant city life. Embrace the urban experience with convenience at your doorstep, including eclectic bars and restaurants. We provide a white noise machine and earplugs, though the lower floor offers a quieter retreat. Experience the best of city living!

The Island View Penthouse
⸻ Welcome to our sophisticated three-bedroom, three-bath retreat in historic Bankers Hill. Enjoy sweeping views, a full modern kitchen, and spacious living areas perfect for relaxing or entertaining. Located just minutes from Balboa Park, downtown, and San Diego’s best dining, this home blends comfort, convenience, and classic neighborhood charm. All rooms feature luxury beds from Davenport Collection. We require minimum 2-night minimum per City code, and a $299 cleaning fee.

Tranquil 4 Bedroom w/ Deck & Backyard
Welcome to this stunning 4 bedroom home in the heart of San Diego. Friends and family are sure to have a wonderful vacation with a fully equipped kitchen, a large comfy couch with a huge TV, speedy wifi, AC, a gigantic backyard, tons of natural light, and ultra cozy beds for a great nights rest. Your group will be able to enjoy beautiful views of the ocean and the city off of the large deck and master bedroom. Don't miss out on this incredible home in San Diego!

New Luxury 3BR/3.5BA Point Loma Coastal One Story
*3BR 3.5BA*1,600 Sq Ft Single Story Living*Indoor Outdoor Living & Entertaining ** Three En Suite Bathrooms***3 Blocks To SD Bay***2 Sets Of W/D***6 TVS***High Speed Fiber Internet***Forced Air HVAC***Heated Outdoor Entertaining Area w BBQ***2 Assigned Parking Spots**EV Charger****10 Ft Ceilings**Italian Marble Counter Tops**8' Solid Core Mahogany Doors**Italian Porcelain Floors**Vaulted Ceilings**Kohler Black Hardware*Village Living***

🌟BEST LOCATION🌟 4BR/2BA - WALK to Little Italy 🇮🇹
Updated craftsman style home in THE BEST location! This beautiful house is close to almost everything San Diego has to offer. Only about a mile or two away from Balboa Park, the Zoo, Old Town, The Gaslamp Quarter, The Embarcadero, Hillcrest and just minutes from the airport. WALK to Little Italy in 10 minutes! Beautiful huge backyard with plenty of room to entertain. GREAT for families, or larger groups!! Sleeps 8 comfortably!

Bright & Modern OB Getaway
This newly built, 2 bedroom/2 bath, is the bright & airy, modern & stylish beach getaway you've been looking for! You'll be located 2 blocks from the beach, and are walking distance to a variety of different restaurants, coffee shops, yoga studios, and nightlife options. The rooftop deck provides an amazing panoramic view for catching sunsets, and even the Sea World fireworks show. Bikes and beach gear ready for use!

Modern ❤️ of South Park, SD skyline, private patio
- Newly renovated home - Historical neighborhood - Spacious front deck patio facing Dog Park - Skyline view of downtown San Diego - Extra large shower - Cozy bedding - Safe street parking - Dog friendly! $75 (2 pets max) Key landmarks - Balboa Park - Balboa Golf Course - 10 min walk to local favorite spots - 10 min drive to downtown San Diego - 15 min drive to SAN Airport
Popular amenities for Downtown San Diego house rentals
House rentals with a pool

Your Modern Lux Pool Resort in the Heart of SD

Casa De Colores

Lionhead - Private Boutique Home

Bright and spacious home with views, pool & spa.

Stunning 2BR/2BA| Plunge Pool, AC, Private

Designer Luxury Rental With Pool

ModernCoastal I View I Pool ITub

Upscale Resort House /Views, Saltwater Pool/Spa !
Weekly house rentals

Designer unit w/FirePit- Petco Park, Zoo, Downtown

South Park Spanish Stunner Renovated & Central

1stResorts.com WATERVIEW FAMILY VILLA HOT TUB YARD

Downtown View - 2 Story House Next to Little Italy

Hillcrest 2 bed 2 en-suite baths garage zen garden

Modern 3BR•Huge Private Yard•Hot Tub•8 Mins to DT

Jacuzzi, Firepit, Sauna & Ice Bath, Rest & Relax

Spacious House close to Petco Park and Gaslamp
Private house rentals

Historic Golden Hill Post Office - 3 BR w fire pit

Peaceful Jungle Retreat In The Heart of San Diego

Hip Home with Spectacular Views

Dreamy Spanish Style Home w/ Large Yard + Hot Tub

Stanton Residence - Downtown Victorian Classic

Coastal Chic Retreat in Bankers Hill

Little Italy Historical

The Sand House-Gorgeous 3BR-2B HotTub+FirePit+Turf
When is the best time to visit Downtown San Diego?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$42,048 GYD | G$44,977 GYD | G$48,952 GYD | G$50,416 GYD | G$49,370 GYD | G$54,809 GYD | G$58,366 GYD | G$50,625 GYD | G$45,814 GYD | G$44,977 GYD | G$44,768 GYD | G$49,579 GYD |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Destinations to explore
- Townhouse rentals Downtown San Diego
- Rentals with a sauna Downtown San Diego
- Boutique hotels Downtown San Diego
- Resort rentals Downtown San Diego
- Rentals with breakfast Downtown San Diego
- Rentals with beach access Downtown San Diego
- Rentals with pools Downtown San Diego
- Hostel rentals Downtown San Diego
- Family-friendly rentals Downtown San Diego
- Waterfront rentals Downtown San Diego
- Rentals with a hot tub Downtown San Diego
- Hotel rooms Downtown San Diego
- Apartment rentals Downtown San Diego
- Loft rentals Downtown San Diego
- Pet-friendly rentals Downtown San Diego
- Condo rentals Downtown San Diego
- Serviced apartment rentals Downtown San Diego
- House rentals San Diego
- House rentals San Diego County
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- SeaWorld San Diego
- Coronado Beach
- Rosarito Beach
- LEGOLAND California
- University of California-San Diego
- San Diego Zoo
- Petco Park
- San Diego Zoo Safari Park
- San Diego Convention Center E Ent
- Pacific Beach
- Balboa Park
- Tijuana Beach
- San Diego State University
- Torrey Pines State Beach
- Mission Beach
- Oceanside City Beach
- Ocean Front Walk
- Las Olas Resort & Spa
- Moonlight State Beach
- La Misión Beach
- Belmont Park
- Sesame Place San Diego
- South Mission Beach, San Diego
- Liberty Station





