House vacation rentals in Downtown San Diego

A modern kitchen features sleek wooden cabinets and white countertops, with a central island that provides additional seating. Stainless steel appliances are present, and a wall of glass allows natural light to fill the space. Cookware hangs elegantly above the island.

4.95 out of 5 average rating, 368 reviews

Walk to Balboa Park and Hillcrest from an Immaculate Home

Take a stroll through the park, then unwind with a leisurely dinner under the festoon lights. Classic crown molding, hardwood floors, and pared-back tones of gray and taupe create an air of calm at this elegant haven spread out over 1500 square feet. You will find the space charming & spacious with over 1500 sq. feet. This single level property is the lower level of a historic duplex. Hardwood floors, crown molding, gas fireplace and laundry room. Street parking is usually readily available. This A+ location of Banker's Hill is NOT impacted by air plane noise. Enjoy the entire lower level duplex and use of the back yard with patio set for dining. Please note the upper tenant may also want to use this space so this area could be shared. We would love to greet you but are also fine with allowing you to access with a code on the front door. We live nearby and are happy to make suggestions for dining or things to do. Located near numerous restaurants, and Balboa Park, Hillcrest, the zoo, Downtown, Little Italy, and the Convention Center are all within 10 minutes. Be at the beach in less than 15 minutes. The bus line runs up First Ave for easy access to Downtown and Uptown. Near trolley and train station. We are within 10 minutes to the San Diego International Airport and a quick Uber ride to Downtown, Little Italy. Walk to the heart of Hillcrest, Balboa Park and the Zoo. Be at the beach in less then 15 minutes. Central location near the I-5, I-163 & I-8. Because of the hardwood floors, you will hear the footsteps above. The kitchen is well stocked if your a cook and we have an area where you can set up your laptop. wireless available and 3 smart TV's for your enjoyment. Small market less than 1 block away.

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Home in Bankers Hill - Park West

A charming Spanish bungalow is framed by vibrant greenery and colorful flowers. A small staircase leads to the main entrance, which features a decorative security screen door. The exterior showcases white stucco walls, accentuated by terracotta details and surrounded by lush tropical plants.

Admire Harbor Views from the Porch at a City Gem

Unwind in a cozy colorful casita in this light-filled 1920s Spanish bungalow decorated with Mexican folklorico. Take a walk into Little Italy for dinner. Or to a show at the Old Globe.What’s best, is how close you are to so much, all without needing a car. A very small single car garage is provided, think compact car. Street parking is free but challenging at times. The house is located directly below the incoming flight path. You are encouraged to read the reviews regarding this.Ideal for four.

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4.96 out of 5 average rating, 511 reviews

Home in Downtown San Diego

A spacious living area features large windows allowing ample natural light. A 85-inch 4K TV is mounted on the wall above a sleek entertainment unit. Comfortable seating includes a plush gray sofa and decorative pillows, with a coffee table at the center of the room.

NEW Luxury 3BR HOUSEof DT Walk Petco w/Garage AC

Located in the heart of Downtown San Diego, this unique house has been completely remodeled and re-imagined to make your stay unforgettable. Designed with the eye toward comfort and entertainment. 7 min walk Petco Park/14 min walk to Convention Center/6 min to Zoo/9 min Airport/12 min to SeaWorld/9 min to Coronado *Stunning bathrooms w/ dual showers, tub, smart glass *Full Kitchen, AC Central *SONOS Sound System, 4K TVs every room *Walk to coffee, yoga & gyms, dining, entertainment, shopping!

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4.91 out of 5 average rating, 211 reviews

Home in Downtown San Diego

Modern Surf Themed Home - Heart of Gaslamp

Step into a modern surf-themed retreat in the vibrant heart of San Diego's Gaslamp Quarter. Perfectly blending laid-back coastal vibes with sleek, urban style, this one-of-a-kind home is designed to be your getaway oasis in the middle of all the action. 7 actual beds no air mattresses or sofa-beds. This is the only 4-bedroom 4-bath for rent in all downtown San Diego. It is close to Convention Center, Petco Park, and Nightlife. This is not a party house. Person booking home must be over 25.

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4.97 out of 5 average rating, 157 reviews

An outdoor patio area showcases a modern gas fire pit with flames reflecting off the smooth surface. A spacious bed is visible through large glass doors, framed by stylish curtains. The warm tones of the interior including a wooden accent wall create a cozy atmosphere.

4.97 out of 5 average rating, 287 reviews

Ventana Vista | Ocean View | EV Charger | Designer

@ventanacollection This cliff-side Mission Hills home is a light filled and custom designed to elevate your future vacation rental expectations. Highlights: - Ocean views from every room - Outdoor patio w/propane firepit and Grill - Modern fully stocked open kitchen with high-end Thermador appliances - Theatre Quality 75" TV and speakers in the plush living room - Premium work from home sit/stand desk, monitor, computer, webcam, speaker set up - Helix and Sleep Night memory foam mattresses

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Home in Downtown San Diego

The exterior of the three-story home is showcased, featuring a warm-colored facade with red doors and decorative balconies. A spacious rooftop deck offers seating and striking views of the surrounding San Diego skyline. The interior layout reveals an open floor plan with comfortable furnishings and natural light.

EpicViews | 3-Stories with Rooftop | Cortez Hill

📍 Unbeatable Central Location! Welcome to Casa Cortez Hill! This charming 3-story home features 3 bedrooms, 2 baths, and a private 4th-story rooftop deck with firepit. At 1,510 sq ft, it comfortably sleeps up to 8 guests. Centrally located—walk to Little Italy, Gaslamp, and Petco Park. Just few miles from the airport and minutes to the beach. Enjoy San Diego’s best dining, nightlife, and coastal vibes. Casa Cortez Hill is your home base for all things San Diego. We can't wait to host you!

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4.99 out of 5 average rating, 148 reviews

A spacious living area is characterized by high ceilings with exposed beams and large windows allowing natural light. A comfortable gray sofa, adorned with colorful cushions, is paired with a bright yellow accent chair. A modern coffee table and entertainment unit complete the inviting space.

4.9 out of 5 average rating, 761 reviews

#1 LOCATION - Rare Luxury Home in Downtown

***THE BEST RATED RENTAL IN DOWNTOWN SAN DIEGO*** Location doesn't get better than this! Right in the heart of the lively Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. Just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & Zoo! All the frills: + Prime location! 98/100 Walker Score rating + Private parking + Private Sundeck & Backyard Stay at this modern luxury home for your next trip!

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An inviting outdoor area features a modern infinity pool, surrounded by lush greenery. Comfortable seating in blue upholstery invites relaxation, while sun loungers provide additional spaces for sunbathing. The serene atmosphere is enhanced by the tranquility of nature in the background.

4.92 out of 5 average rating, 183 reviews

Pool Oasis in Central Hillcrest by Park/Zoo

The enormous infinite edge pool floats above the jungle floor. Perched on a private canyon, this modern house is conveniently located in the heart of Hillcrest, walking distance to restaurants, bars, Balboa Park, the San Diego Zoo. Private paradise in walking neighborhood! Multiple private work spaces with treetop views. Cinema room with surround sound! NOTE: Not suitable for young children (heights, noise restrictions, breakables). NO PETS! NO PARTIES! (STRICT!). TOT# 641946.

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A bright living area features large floor-to-ceiling windows allowing ample natural light. A light wood coffee table is situated in front of a comfortable sofa adorned with decorative pillows. A large television stands on a modern console, with a potted plant adding a touch of greenery.

4.83 out of 5 average rating, 225 reviews

Little Italy 2BR Loft Near Waterfront & Convention

Discover the heart of San Diego from our spacious loft in Little Italy, the culinary gem of downtown. Perfectly situated for both business and leisure travelers, you're steps away from the waterfront, convention center, and vibrant city life. Embrace the urban experience with convenience at your doorstep, including eclectic bars and restaurants. We provide a white noise machine and earplugs, though the lower floor offers a quieter retreat. Experience the best of city living!

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Home in Bankers Hill - Park West

The Island View Penthouse

⸻ Welcome to our sophisticated three-bedroom, three-bath retreat in historic Bankers Hill. Enjoy sweeping views, a full modern kitchen, and spacious living areas perfect for relaxing or entertaining. Located just minutes from Balboa Park, downtown, and San Diego’s best dining, this home blends comfort, convenience, and classic neighborhood charm. All rooms feature luxury beds from Davenport Collection. We require minimum 2-night minimum per City code, and a $299 cleaning fee.

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4.98 out of 5 average rating, 132 reviews

A spacious living area is presented with a soft sofa adorned with decorative pillows. The room features large windows that offer views of the city skyline and Interstate 5. Warm lighting from a ceiling fixture complements the wooden beams overhead, enhancing the inviting atmosphere.

4.98 out of 5 average rating, 320 reviews

Downtown View - 2 Story House Next to Little Italy

Two story house with 2 living rooms; 3 blocks to Little Italy restaurants, bars, & shops. Near Balboa Park, San Diego Zoo, Gaslamp, Waterfront Park & the Harbor. Museums, restaurants, theaters & nature are all nearby. Located in historic Bankers Hill, next to Interstate 5, near the airport and city center. With 2 living rooms, my house is perfect for travelers needing separate space. One parking spot is available. Extra large vehicles will have to park on the street.

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4.93 out of 5 average rating, 121 reviews

Luxury 7 BR Mission Hills Home with a View

Incredible 7 BR and 4.5 bath home with amazing views of downtown San Diego. Two story wrap around deck complete with two full kitchens. Complete remodel with stylish upgrades. Great open spaces and indoor / outdoor living with wrap around two story deck. On a quiet culdesac with 3 dedicated parking spaces whether you wish to enjoy a family getaway or executive retreat you will love the central location with the peaceful and tranquil views

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Popular amenities for Downtown San Diego house rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

House rentals with a pool

A vibrant heated pool is surrounded by minimalistic landscaping, featuring tall cacti and a clean white fence. Soft lounge chairs are positioned nearby for relaxation. The clear water reflects the blue sky, creating a refreshing setting for leisure and enjoyment.

4.93 out of 5 average rating, 293 reviews

Lionhead - Private Boutique Home

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5.0 out of 5 average rating, 299 reviews

A private outdoor area features a heated pool surrounded by lush green grass and modern loungers. An inviting fire pit is centrally located, with two stylish chairs positioned nearby. The backdrop includes well-maintained shrubbery and tall trees, enhancing the tranquil ambiance.

Home in Serra Mesa

Midcentury Lux 4BR home w Pool/Spa/Cabana/Firepit

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Home in University Heights

An aerial view captures the spacious outdoor area, featuring a rectangular pool surrounded by sun loungers and umbrellas. Lush greenery is visible alongside neatly arranged pathways and stone retaining walls, complementing the mountain-modern design of the home in the background.

Your Modern Lux Pool Resort in the Heart of SD

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4.9 out of 5 average rating, 185 reviews

Home in University Heights

A well-lit bedroom features a spacious bed with neutral bedding and striped pillows. Natural light enters through glass doors leading to a semi-private patio. A textured area rug and a potted plant add subtle warmth to the wood flooring.

Cozy University Heights Cottage

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4.86 out of 5 average rating, 124 reviews

4.94 out of 5 average rating, 147 reviews

A living room features a luxury hanging chair suspended from the ceiling. Natural light filters through sheer curtains, illuminating a cozy seating area with a plush sofa and wooden coffee table. A 50” television is mounted above an elegant fireplace, enhancing the room's comfort.

Home in City Heights

Designer Luxury Rental With Pool

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4.98 out of 5 average rating, 122 reviews

Home in Normal Heights

Private Heated Pool | Sleeps 10

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Home in Greater North Park

An outdoor living space is showcased, featuring a circular pool surrounded by wooden decking. Comfortable lounge seating with dark cushions and a fire pit is positioned under string lights. Umbrellas provide shade while a gas grill is visible nearby, creating an inviting atmosphere.

Stylish Family Home I Near Dining, Shopping + Zoo

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4.95 out of 5 average rating, 198 reviews

4.92 out of 5 average rating, 128 reviews

A spacious outdoor patio showcases a private pool and hot tub, surrounded by comfortable seating and a fire pit. An activity area features games such as foosball and cornhole, with lounge chairs positioned for relaxation. Lush green landscaping complements the inviting space.

Home in Bay Park

Modern Central SD Home w/ Pool & Spa Near Beach

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Weekly house rentals

An open floor plan connects the living area to the kitchen, with a dining table set for four. A large window allows natural light to illuminate the space, while a modern TV is mounted on the wall. Comfortable seating is arranged nearby.

4.94 out of 5 average rating, 102 reviews

1stResorts.com WATERVIEW FAMILY VILLA HOT TUB YARD

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Home in Greater North Park

Designer Unit w/FirePit-Petco Park, Zoo, Downtown

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4.97 out of 5 average rating, 118 reviews

4.92 out of 5 average rating, 380 reviews

A spacious bedroom features a comfortable bed with multiple pillows and a decorative throw. Natural light enters through a window, complemented by sleek gray curtains. A dresser and bedside tables provide storage, while a ceiling fan adds to the airy ambiance.

Home in Golden Hill

5 Bed 2 Bath Victorian Carriage House | Parking

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5.0 out of 5 average rating, 303 reviews

New Luxury 3BR/3.5BA Point Loma Coastal One Story

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Home in Greater North Park

Hot Tub Oasis | Walkable North Park | Top 1%

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5.0 out of 5 average rating, 190 reviews

A charming two-story house is illuminated at night, showcasing architectural details such as a turret and decorative trim. A staircase leads to a welcoming porch, surrounded by greenery and soft lighting that enhances the inviting atmosphere of the exterior.

4.96 out of 5 average rating, 165 reviews

STUNNING MANSION THE BEST LOCATION & AMENITIES

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The exterior of the bungalow features a welcoming entrance with a large covered porch, flanked by vibrant palm trees and landscaped greenery. The property number is clearly displayed, and a wooden fence surrounds the yard, providing a sense of privacy.

4.98 out of 5 average rating, 434 reviews

Hillcrest 2 bed 2 en-suite baths garage zen garden

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A charming historical property features a teal-colored exterior with white trim and a covered front porch. Large windows allow natural light to enter, while the surrounding landscape includes lush greenery. A red vehicle is parked nearby, enhancing the welcoming environment.

4.98 out of 5 average rating, 112 reviews

Little Italy Historical

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Private house rentals

The living area features a spacious sectional sofa facing a modern television mounted above a stone fireplace. A round white coffee table is positioned centrally on a polished floor, while a potted plant adds a touch of greenery. Natural light floods in through the large window.

4.95 out of 5 average rating, 129 reviews

Central Charm in Hillcrest near Scripps Mercy

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An outdoor terrace features comfortable seating with plush cushions, surrounded by a sleek railing. A dining table with wicker chairs is shaded by a large umbrella. The skyline of San Diego and a vibrant sunset create a stunning backdrop in the distance.

4.97 out of 5 average rating, 143 reviews

The California

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A spacious backyard is highlighted by outdoor seating arrangements around a modern fire pit. Ambient lighting frames the area, while a dining table and BBQ grill are visible, providing inviting options for outdoor gatherings.

4.93 out of 5 average rating, 166 reviews

Modern 3BR•Huge Private Yard•Hot Tub•8 Mins to DT

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Home in Bankers Hill - Park West

San Diego House: City Views, BBQ & Free Parking!

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4.84 out of 5 average rating, 423 reviews

4.89 out of 5 average rating, 122 reviews

Stylish San Diego Home with Hot Tub Near SDSU

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The entrance of a historic craftsman house is framed by lush greenery and palm trees. A set of blue steps leads to a covered porch doorway, which is adorned with a flag. Natural stones border the path, providing a welcoming approach.

4.88 out of 5 average rating, 294 reviews

A Charming House. Short walk to Balboa park & Zoo!

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4.88 out of 5 average rating, 161 reviews

A modern great room features a large flat-screen TV displaying a serene landscape. A round glass table sits in the center, surrounded by a plush sofa and accent seating. Natural light floods the space through expansive glass doors, revealing a private courtyard with a fire pit.

Home in Golden Hill

Historic Post Office loft 4 Bed + firepit Near Zoo

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