House vacation rentals in Downtown San Diego

A charming Spanish bungalow is framed by vibrant greenery and colorful flowers. A small staircase leads to the main entrance, which features a decorative security screen door. The exterior showcases white stucco walls, accentuated by terracotta details and surrounded by lush tropical plants.

4.96 out of 5 average rating, 511 reviews

Admire Harbor Views from the Porch at a City Gem

Unwind in a cozy colorful casita in this light-filled 1920s Spanish bungalow decorated with Mexican folklorico. Take a walk into Little Italy for dinner. Or to a show at the Old Globe.What’s best, is how close you are to so much, all without needing a car. A very small single car garage is provided, think compact car. Street parking is free but challenging at times. The house is located directly below the incoming flight path. You are encouraged to read the reviews regarding this.Ideal for four.

An open floor plan connects the living area to the kitchen, with a dining table set for four. A large window allows natural light to illuminate the space, while a modern TV is mounted on the wall. Comfortable seating is arranged nearby.

4.94 out of 5 average rating, 102 reviews

1stResorts.com WATERVIEW FAMILY VILLA HOT TUB YARD

Brand New FAMILY Villa: Full kitchen, Private back deck off living space & Private yard! Private Hot tub/fire pit & outdoor furniture! Near Sea World, the Zoo, other great activities for children & great restaurants! Near Little Italy, Balboa Park, Liberty Station, Seaport Village! 2 bedrooms w/king beds, 1 full bathroom w/shower & double sinks. Powder room, free private washer/dryer. Private Barbecue grill. Beach towels, queen pullout sofa bed. Back deck connected to living area & private yard!

Home in Downtown San Diego

A spacious living area features large windows allowing ample natural light. A 85-inch 4K TV is mounted on the wall above a sleek entertainment unit. Comfortable seating includes a plush gray sofa and decorative pillows, with a coffee table at the center of the room.

4.92 out of 5 average rating, 212 reviews

NEW Luxury 3BR HOUSEof DT Walk Petco w/Garage AC

Located in the heart of Downtown San Diego, this unique house has been completely remodeled and re-imagined to make your stay unforgettable. Designed with the eye toward comfort and entertainment. 7 min walk Petco Park/14 min walk to Convention Center/6 min to Zoo/9 min Airport/12 min to SeaWorld/9 min to Coronado *Stunning bathrooms w/ dual showers, tub, smart glass *Full Kitchen, AC Central *SONOS Sound System, 4K TVs every room *Walk to coffee, yoga & gyms, dining, entertainment, shopping!

Home in Downtown San Diego

The exterior of the three-story home is showcased, featuring a warm-colored facade with red doors and decorative balconies. A spacious rooftop deck offers seating and striking views of the surrounding San Diego skyline. The interior layout reveals an open floor plan with comfortable furnishings and natural light.

4.99 out of 5 average rating, 148 reviews

EpicViews | 3-Stories with Rooftop | Cortez Hill

📍 Unbeatable Central Location! Welcome to Casa Cortez Hill! This charming 3-story home features 3 bedrooms, 2 baths, and a private 4th-story rooftop deck with firepit. At 1,510 sq ft, it comfortably sleeps up to 8 guests. Centrally located—walk to Little Italy, Gaslamp, and Petco Park. Just few miles from the airport and minutes to the beach. Enjoy San Diego’s best dining, nightlife, and coastal vibes. Casa Cortez Hill is your home base for all things San Diego. We can't wait to host you!

A spacious living area is characterized by high ceilings with exposed beams and large windows allowing natural light. A comfortable gray sofa, adorned with colorful cushions, is paired with a bright yellow accent chair. A modern coffee table and entertainment unit complete the inviting space.

4.9 out of 5 average rating, 763 reviews

#1 LOCATION - Rare Luxury Home in Downtown

***THE BEST RATED RENTAL IN DOWNTOWN SAN DIEGO*** Location doesn't get better than this! Right in the heart of the lively Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. Just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & Zoo! All the frills: + Prime location! 98/100 Walker Score rating + Private parking + Private Sundeck & Backyard Stay at this modern luxury home for your next trip!

4.92 out of 5 average rating, 382 reviews

A spacious bedroom features a comfortable bed with multiple pillows and a decorative throw. Natural light enters through a window, complemented by sleek gray curtains. A dresser and bedside tables provide storage, while a ceiling fan adds to the airy ambiance.

Home in Golden Hill

5 Bed 2 Bath Victorian Carriage House | Parking

Capture the essence of San Diego in our 2 story Victorian carriage house hosted by Ethos Vacation Homes with 3 bedrooms and 2 baths. The historical building features elite comfort for up to 10 guests with central A/C and heating, 5 comfortable king and queen size beds, FREE laundry, 4 enormous HDTVs, Netflix, Max, Hulu, Starz, Showtime, Disney+, Apple+, Paramount+ and ESPN+. This spacious San Diego vacation rental home has everything you need for your California Dreaming Vacation!

A bright living area features large floor-to-ceiling windows allowing ample natural light. A light wood coffee table is situated in front of a comfortable sofa adorned with decorative pillows. A large television stands on a modern console, with a potted plant adding a touch of greenery.

4.83 out of 5 average rating, 227 reviews

Little Italy 2BR Loft Near Waterfront & Convention

Discover the heart of San Diego from our spacious loft in Little Italy, the culinary gem of downtown. Perfectly situated for both business and leisure travelers, you're steps away from the waterfront, convention center, and vibrant city life. Embrace the urban experience with convenience at your doorstep, including eclectic bars and restaurants. We provide a white noise machine and earplugs, though the lower floor offers a quieter retreat. Experience the best of city living!

4.98 out of 5 average rating, 133 reviews

The Island View Penthouse

⸻ Welcome to our sophisticated three-bedroom, three-bath retreat in historic Bankers Hill. Enjoy sweeping views, a full modern kitchen, and spacious living areas perfect for relaxing or entertaining. Located just minutes from Balboa Park, downtown, and San Diego’s best dining, this home blends comfort, convenience, and classic neighborhood charm. All rooms feature luxury beds from Davenport Collection. We require minimum 2-night minimum per City code, and a $299 cleaning fee.

A spacious living area is presented with a soft sofa adorned with decorative pillows. The room features large windows that offer views of the city skyline and Interstate 5. Warm lighting from a ceiling fixture complements the wooden beams overhead, enhancing the inviting atmosphere.

4.98 out of 5 average rating, 322 reviews

Downtown View - 2 Story House Next to Little Italy

Two story house with 2 living rooms; 3 blocks to Little Italy restaurants, bars, & shops. Near Balboa Park, San Diego Zoo, Gaslamp, Waterfront Park & the Harbor. Museums, restaurants, theaters & nature are all nearby. Located in historic Bankers Hill, next to Interstate 5, near the airport and city center. With 2 living rooms, my house is perfect for travelers needing separate space. One parking spot is available. Extra large vehicles will have to park on the street.

A spacious living area is highlighted by vaulted ceilings and floor-to-ceiling windows offering expansive city views. Modern seating includes a light grey sofa, orange armchairs, and a round white coffee table. The open kitchen is visible in the background, featuring bar seating and contemporary finishes.

4.9 out of 5 average rating, 172 reviews

Heated Pool|Jacuzzi|King Bed|City Views|Chic Decor

⚜ Stunning wrap-around balcony with panoramic city views ⚜ Heated pool with jacuzzi ($125/day to heat — request in advance) ⚜ 2,500 sq-ft of interior space with vaulted ceilings & open floor plan ⚜ Chic modern décor throughout ⚜ Two fully stocked kitchens ⚜ 4 king beds, 1 sofa bed & 1 couch ⚜ Poolside sun loungers & outdoor lounge areas ⚜ Complimentary washer & dryer ⚜ Attached studio suite with private access (included) ⚜ Located in Historic Mission Hills, San Diego

4.93 out of 5 average rating, 122 reviews

Luxury 7 BR Mission Hills Home with a View

Incredible 7 BR and 4.5 bath home with amazing views of downtown San Diego. Two story wrap around deck complete with two full kitchens. Complete remodel with stylish upgrades. Great open spaces and indoor / outdoor living with wrap around two story deck. On a quiet culdesac with 3 dedicated parking spaces whether you wish to enjoy a family getaway or executive retreat you will love the central location with the peaceful and tranquil views

5.0 out of 5 average rating, 306 reviews

New Luxury 3BR/3.5BA Point Loma Coastal One Story

*3BR 3.5BA*1,600 Sq Ft Single Story Living*Indoor Outdoor Living & Entertaining ** Three En Suite Bathrooms***3 Blocks To SD Bay***2 Sets Of W/D***6 TVS***High Speed Fiber Internet***Forced Air HVAC***Heated Outdoor Entertaining Area w BBQ***2 Assigned Parking Spots**EV Charger****10 Ft Ceilings**Italian Marble Counter Tops**8' Solid Core Mahogany Doors**Italian Porcelain Floors**Vaulted Ceilings**Kohler Black Hardware*Village Living***

Popular amenities for Downtown San Diego house rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

House rentals with a pool

5.0 out of 5 average rating, 301 reviews

A private outdoor area features a heated pool surrounded by lush green grass and modern loungers. An inviting fire pit is centrally located, with two stylish chairs positioned nearby. The backdrop includes well-maintained shrubbery and tall trees, enhancing the tranquil ambiance.

Home in Serra Mesa

Midcentury Lux 4BR home w Pool/Spa/Cabana/Firepit

4.98 out of 5 average rating, 124 reviews

Home in Normal Heights

Family Oasis w/ Heated Pool

4.92 out of 5 average rating, 129 reviews

A spacious outdoor patio showcases a private pool and hot tub, surrounded by comfortable seating and a fire pit. An activity area features games such as foosball and cornhole, with lounge chairs positioned for relaxation. Lush green landscaping complements the inviting space.

Home in Bay Park

Modern Central SD Home w/ Pool & Spa Near Beach

Home in University Heights

An aerial view captures the spacious outdoor area, featuring a rectangular pool surrounded by sun loungers and umbrellas. Lush greenery is visible alongside neatly arranged pathways and stone retaining walls, complementing the mountain-modern design of the home in the background.

4.9 out of 5 average rating, 188 reviews

Your Modern Lux Pool Resort in the Heart of SD

A spacious backyard is showcased with a glistening pool surrounded by a concrete deck. Green grass offers a soft contrast, while lounge chairs and a shaded seating area are positioned for relaxation. String lights illuminate the space, enhancing the outdoor ambiance during twilight.

4.95 out of 5 average rating, 110 reviews

San Diego Pool House with Luxury King/Queen Suites

A vibrant heated pool is surrounded by minimalistic landscaping, featuring tall cacti and a clean white fence. Soft lounge chairs are positioned nearby for relaxation. The clear water reflects the blue sky, creating a refreshing setting for leisure and enjoyment.

4.93 out of 5 average rating, 293 reviews

Lionhead - Private Boutique Home

4.94 out of 5 average rating, 148 reviews

A living room features a luxury hanging chair suspended from the ceiling. Natural light filters through sheer curtains, illuminating a cozy seating area with a plush sofa and wooden coffee table. A 50” television is mounted above an elegant fireplace, enhancing the room's comfort.

Home in City Heights

Designer Luxury Rental With Pool

A dining area is highlighted by a round wooden table surrounded by six wooden chairs. A cozy blue sofa is positioned nearby, with large glass doors opening to a pool area. Natural light enhances the space, complemented by a modern pendant light overhead.

4.92 out of 5 average rating, 101 reviews

San Diego Oasis- A Retro Retreat w/ King Size Bed!

Weekly house rentals

4.92 out of 5 average rating, 183 reviews

An inviting outdoor area features a modern infinity pool, surrounded by lush greenery. Comfortable seating in blue upholstery invites relaxation, while sun loungers provide additional spaces for sunbathing. The serene atmosphere is enhanced by the tranquility of nature in the background.

Home in Hillcrest

Pool Oasis in Central Hillcrest by Park/Zoo

4.95 out of 5 average rating, 370 reviews

A modern kitchen features sleek wooden cabinets and white countertops, with a central island that provides additional seating. Stainless steel appliances are present, and a wall of glass allows natural light to fill the space. Cookware hangs elegantly above the island.

Home in Hillcrest

Walk to Balboa Park and Hillcrest from an Immaculate Home

4.84 out of 5 average rating, 423 reviews

San Diego House: City Views, BBQ & Free Parking!

4.91 out of 5 average rating, 197 reviews

Home in Barrio Logan

Convention Center | Petco Park | Free Parking

An outdoor patio area showcases a modern gas fire pit with flames reflecting off the smooth surface. A spacious bed is visible through large glass doors, framed by stylish curtains. The warm tones of the interior including a wooden accent wall create a cozy atmosphere.

4.97 out of 5 average rating, 289 reviews

Ventana Vista | Ocean View | EV Charger | Designer

4.89 out of 5 average rating, 227 reviews

A spacious private patio is illuminated by string lights, creating a cozy outdoor setting. A fire pit sits at the center, surrounded by modern seating. Large glass doors open to the interior, allowing for an open transition between indoor and outdoor spaces.

Home in Golden Hill

Historic Golden Hill Post Office - 3 BR w fire pit

A grand mansion features Tudor architectural details with a distinctive facade, characterized by a steeply pitched roof and decorative brickwork. Lush greenery surrounds the entrance, while two lion statues stand proudly at the base of the staircase leading to the front door.

4.89 out of 5 average rating, 148 reviews

Stunning Mansion by The ConventionC & LittleItaly

4.98 out of 5 average rating, 201 reviews

Condé Nast Villa | Speakeasy · Hot Tub · Sleeps 10

Private house rentals

Home in Downtown San Diego

A contemporary living space features a leather sectional sofa arranged around a low coffee table. Bright red walls complement the artwork displayed, with large windows allowing natural light to fill the room. A flat-screen TV is mounted on one wall, creating a relaxed atmosphere.

4.84 out of 5 average rating, 351 reviews

Walk to Petco Park, Downtown, Gaslamp w/ garage!

A spacious backyard is highlighted by outdoor seating arrangements around a modern fire pit. Ambient lighting frames the area, while a dining table and BBQ grill are visible, providing inviting options for outdoor gatherings.

4.93 out of 5 average rating, 166 reviews

Modern 3BR•Huge Private Yard•Hot Tub•8 Mins to DT

4.9 out of 5 average rating, 124 reviews

Stylish San Diego Home with Hot Tub Near SDSU

A charming historical property features a teal-colored exterior with white trim and a covered front porch. Large windows allow natural light to enter, while the surrounding landscape includes lush greenery. A red vehicle is parked nearby, enhancing the welcoming environment.

4.98 out of 5 average rating, 113 reviews

Little Italy Historical

A modern living area features a dark leather couch opposite a light grey sectional sofa, both arranged around a central coffee table. Natural light filters through covered windows, and a flat-screen TV sits atop a sleek stand. An air conditioning unit is positioned on the wall.

4.99 out of 5 average rating, 451 reviews

3bd (TV and AC), 2ba, 15-20 minutes to everything

A spacious living area features a sectional sofa positioned around a coffee table. Large sliding glass doors lead to an outdoor patio, allowing natural light to fill the room. A projector is mounted on the ceiling, highlighting the entertainment options available.

4.9 out of 5 average rating, 173 reviews

Spacious House close to Petco Park and Gaslamp

A welcoming living area features large windows that provide ample natural light and views of the surroundings. A round dining table is paired with several chairs, while a cozy seating area includes a sofa and a plant. The space is complemented by a textured area rug.

4.9 out of 5 average rating, 166 reviews

Central Little Italy Bayview House