House vacation rentals in Downtown San Diego

Find and book unique houses on Airbnb

Quick stats about house rentals in Downtown San Diego

  • Total vacation rentals

    Explore 170 vacation rentals in Downtown San Diego

  • Nightly prices starting at

    Downtown San Diego vacation rentals start at G$12,554 GYD per night before taxes and fees

  • Verified guest reviews

    Over 14,860 verified reviews to help you choose

  • Family-friendly vacation rentals

    110 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 60 rentals that welcome pets

  • Rentals with dedicated workspaces

    80 properties have a dedicated workspace

  • Wi-Fi availability

    160 of Downtown San Diego vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Downtown San Diego rentals

  • 4.8 Average rating

    Downtown San Diego stays are highly rated by guests—averaging 4.8 out of 5!

Top-rated house rentals in Downtown San Diego

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Top guest favorite
A modern kitchen features sleek wooden cabinets and white countertops, with a central island that provides additional seating. Stainless steel appliances are present, and a wall of glass allows natural light to fill the space. Cookware hangs elegantly above the island.
Home in Hillcrest

Walk to Balboa Park and Hillcrest from an Immaculate Home

Take a stroll through the park, then unwind with a leisurely dinner under the festoon lights. Classic crown molding, hardwood floors, and pared-back tones of gray and taupe create an air of calm at this elegant haven spread out over 1500 square feet. You will find the space charming & spacious with over 1500 sq. feet. This single level property is the lower level of a historic duplex. Hardwood floors, crown molding, gas fireplace and laundry room. Street parking is usually readily available. This A+ location of Banker's Hill is NOT impacted by air plane noise. Enjoy the entire lower level duplex and use of the back yard with patio set for dining. Please note the upper tenant may also want to use this space so this area could be shared. We would love to greet you but are also fine with allowing you to access with a code on the front door. We live nearby and are happy to make suggestions for dining or things to do. Located near numerous restaurants, and Balboa Park, Hillcrest, the zoo, Downtown, Little Italy, and the Convention Center are all within 10 minutes. Be at the beach in less than 15 minutes. The bus line runs up First Ave for easy access to Downtown and Uptown. Near trolley and train station. We are within 10 minutes to the San Diego International Airport and a quick Uber ride to Downtown, Little Italy. Walk to the heart of Hillcrest, Balboa Park and the Zoo. Be at the beach in less then 15 minutes. Central location near the I-5, I-163 & I-8. Because of the hardwood floors, you will hear the footsteps above. The kitchen is well stocked if your a cook and we have an area where you can set up your laptop. wireless available and 3 smart TV's for your enjoyment. Small market less than 1 block away.

FamilyValueHospitality

4.95 out of 5 average rating, 370 reviews
Top guest favorite
A charming Spanish bungalow is framed by vibrant greenery and colorful flowers. A small staircase leads to the main entrance, which features a decorative security screen door. The exterior showcases white stucco walls, accentuated by terracotta details and surrounded by lush tropical plants.
Home in Bankers Hill - Park West

Admire Harbor Views from the Porch at a City Gem

Unwind in a cozy colorful casita in this light-filled 1920s Spanish bungalow decorated with Mexican folklorico. Take a walk into Little Italy for dinner. Or to a show at the Old Globe.What’s best, is how close you are to so much, all without needing a car. A very small single car garage is provided, think compact car. Street parking is free but challenging at times. The house is located directly below the incoming flight path. You are encouraged to read the reviews regarding this.Ideal for four.

FamilyLocationCheckout

4.95 out of 5 average rating, 512 reviews
Top guest favorite
An open floor plan connects the living area to the kitchen, with a dining table set for four. A large window allows natural light to illuminate the space, while a modern TV is mounted on the wall. Comfortable seating is arranged nearby.
Home in San Diego

1stResorts.com WATERVIEW FAMILY VILLA HOT TUB YARD

Brand New FAMILY Villa: Full kitchen, Private back deck off living space & Private yard! Private Hot tub/fire pit & outdoor furniture! Near Sea World, the Zoo, other great activities for children & great restaurants! Near Little Italy, Balboa Park, Liberty Station, Seaport Village! 2 bedrooms w/king beds, 1 full bathroom w/shower & double sinks. Powder room, free private washer/dryer. Private Barbecue grill. Beach towels, queen pullout sofa bed. Back deck connected to living area & private yard!

LocationFamilyOutdoor spaces

4.94 out of 5 average rating, 103 reviews
Top guest favorite
A cozy living area features a vibrant red sectional sofa adorned with colorful throw pillows. A rustic wooden coffee table is positioned in front, topped with a decorative plate. Artworks decorate the walls, adding to the room's inviting feel.
Home in South Park

Comfy, cozy, colorful in South Park

Enjoy beautiful San Diego in the comfort of a charming neighborhood home with your own private entrance. A great place for families with kids, couples, and solo adventurers. WE DO NOT PERMIT PARTIES Spacious and sunny house in desirable and convenient South Park location, walking distance from charming Fern Street with its shops and restaurants, near to Balboa Park, Balboa Park Golf Course, San Diego Zoo, and easy access to downtown, Gaslamp Quarter, Convention Center and local area beaches.

FamilyLocationWifi

4.98 out of 5 average rating, 772 reviews
Top guest favorite
A charming historical property features a teal-colored exterior with white trim and a covered front porch. Large windows allow natural light to enter, while the surrounding landscape includes lush greenery. A red vehicle is parked nearby, enhancing the welcoming environment.
Home in Little Italy

Little Italy Historical

This AirBNB residence is a recently fully renovated historical property in San Diego’s Little Italy community. Many say it’s one of the finest. It is only 3 short blocks from Little Italy’s vibrant India Street and its many restaurants, bars, cafes, and shops, and four from the Trolley. It’s also a short drive to San Diego’s beaches and attractions. The AirBNB unit is a ground floor private one bed/one bath suite with a living room and its own entrances. Pics and descriptions are enclosed.

FamilyValueCheck-in

4.98 out of 5 average rating, 114 reviews
Superhost
A spacious living area features large windows allowing ample natural light. A 85-inch 4K TV is mounted on the wall above a sleek entertainment unit. Comfortable seating includes a plush gray sofa and decorative pillows, with a coffee table at the center of the room.
Home in Downtown San Diego

NEW Luxury 3BR HOUSEof DT Walk Petco w/Garage AC

Located in the heart of Downtown San Diego, this unique house has been completely remodeled and re-imagined to make your stay unforgettable. Designed with the eye toward comfort and entertainment. 7 min walk Petco Park/14 min walk to Convention Center/6 min to Zoo/9 min Airport/12 min to SeaWorld/9 min to Coronado *Stunning bathrooms w/ dual showers, tub, smart glass *Full Kitchen, AC Central *SONOS Sound System, 4K TVs every room *Walk to coffee, yoga & gyms, dining, entertainment, shopping!

ValueFamilyLong stay

4.92 out of 5 average rating, 213 reviews
Top guest favorite
Home in Downtown San Diego

Modern Surf Themed Home - Heart of Gaslamp

Step into a modern surf-themed retreat in the vibrant heart of San Diego's Gaslamp Quarter. Perfectly blending laid-back coastal vibes with sleek, urban style, this one-of-a-kind home is designed to be your getaway oasis in the middle of all the action. 7 actual beds no air mattresses or sofa-beds. This is the only 4-bedroom 4-bath for rent in all downtown San Diego. It is close to Convention Center, Petco Park, and Nightlife. This is not a party house. Person booking home must be over 25.

FamilyLocationQuiet

4.97 out of 5 average rating, 157 reviews
Guest favorite
The exterior of the three-story home is showcased, featuring a warm-colored facade with red doors and decorative balconies. A spacious rooftop deck offers seating and striking views of the surrounding San Diego skyline. The interior layout reveals an open floor plan with comfortable furnishings and natural light.
Home in Downtown San Diego

EpicViews | 3-Stories with Rooftop | Cortez Hill

📍 Unbeatable Central Location! Welcome to Casa Cortez Hill! This charming 3-story home features 3 bedrooms, 2 baths, and a private 4th-story rooftop deck with firepit. At 1,510 sq ft, it comfortably sleeps up to 8 guests. Centrally located—walk to Little Italy, Gaslamp, and Petco Park. Just few miles from the airport and minutes to the beach. Enjoy San Diego’s best dining, nightlife, and coastal vibes. Casa Cortez Hill is your home base for all things San Diego. We can't wait to host you!

FamilyValueGetting around

4.99 out of 5 average rating, 148 reviews
Guest favorite
A spacious living area is characterized by high ceilings with exposed beams and large windows allowing natural light. A comfortable gray sofa, adorned with colorful cushions, is paired with a bright yellow accent chair. A modern coffee table and entertainment unit complete the inviting space.
Home in Little Italy

#1 LOCATION - Rare Luxury Home in Downtown

***THE BEST RATED RENTAL IN DOWNTOWN SAN DIEGO*** Location doesn't get better than this! Right in the heart of the lively Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. Just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & Zoo! All the frills: + Prime location! 98/100 Walker Score rating + Private parking + Private Sundeck & Backyard Stay at this modern luxury home for your next trip!

ValueLocationOutdoor spaces

4.9 out of 5 average rating, 764 reviews
Guest favorite
A spacious bedroom features a comfortable bed with multiple pillows and a decorative throw. Natural light enters through a window, complemented by sleek gray curtains. A dresser and bedside tables provide storage, while a ceiling fan adds to the airy ambiance.
Home in Golden Hill

5 Bed 2 Bath Victorian Carriage House | Parking

Capture the essence of San Diego in our 2 story Victorian carriage house hosted by Ethos Vacation Homes with 3 bedrooms and 2 baths. The historical building features elite comfort for up to 10 guests with central A/C and heating, 5 comfortable king and queen size beds, FREE laundry, 4 enormous HDTVs, Netflix, Max, Hulu, Starz, Showtime, Disney+, Apple+, Paramount+ and ESPN+. This spacious San Diego vacation rental home has everything you need for your California Dreaming Vacation!

FamilyValueKitchen

4.92 out of 5 average rating, 383 reviews
Top guest favorite
An inviting outdoor area features a modern infinity pool, surrounded by lush greenery. Comfortable seating in blue upholstery invites relaxation, while sun loungers provide additional spaces for sunbathing. The serene atmosphere is enhanced by the tranquility of nature in the background.
Home in Hillcrest

Pool Oasis in Central Hillcrest by Park/Zoo

The enormous infinite edge pool floats above the jungle floor. Perched on a private canyon, this modern house is conveniently located in the heart of Hillcrest, walking distance to restaurants, bars, Balboa Park, the San Diego Zoo. Private paradise in walking neighborhood! Multiple private work spaces with treetop views. Cinema room with surround sound! NOTE: Not suitable for young children (heights, noise restrictions, breakables). NO PETS! NO PARTIES! (STRICT!). TOT# 641946.

ValueLocationAccuracy

4.92 out of 5 average rating, 185 reviews
Superhost
A bright living area features large floor-to-ceiling windows allowing ample natural light. A light wood coffee table is situated in front of a comfortable sofa adorned with decorative pillows. A large television stands on a modern console, with a potted plant adding a touch of greenery.
Home in Little Italy

Little Italy 2BR Loft Near Waterfront & Convention

Discover the heart of San Diego from our spacious loft in Little Italy, the culinary gem of downtown. Perfectly situated for both business and leisure travelers, you're steps away from the waterfront, convention center, and vibrant city life. Embrace the urban experience with convenience at your doorstep, including eclectic bars and restaurants. We provide a white noise machine and earplugs, though the lower floor offers a quieter retreat. Experience the best of city living!

LocationValueParking

4.83 out of 5 average rating, 228 reviews

Popular amenities for Downtown San Diego house rentals

Private house rentals

Guest favorite
A contemporary living space features a leather sectional sofa arranged around a low coffee table. Bright red walls complement the artwork displayed, with large windows allowing natural light to fill the room. A flat-screen TV is mounted on one wall, creating a relaxed atmosphere.
Home in Downtown San Diego

Walk to Petco Park, Downtown, Gaslamp w/ garage!

LocationValueHeating

4.84 out of 5 average rating, 352 reviews
Top guest favorite
A well-equipped kitchen features a charming wooden island with bar stools, surrounded by modern appliances. Light streams through multiple windows, illuminating the cozy living area visible in the background. The warm tones of the wood beams and flooring enhance the welcoming atmosphere.
Home in Mission Hills

Beautiful Canyon Cottage located on a huge lot

FamilyLocationAir conditioning

4.96 out of 5 average rating, 164 reviews
Top guest favorite
A bright sleeping area features a spacious bed with crisp linens against a modern grey headboard. A sleek red chair is positioned by large windows, providing natural light and neighborhood views. A wall-mounted television is visible, along with minimalist decor and light wood flooring.
Home in Greater North Park

Sunlit 3-Story Iconic Modern Gem in North Park

LocationFamilyCheckout

4.98 out of 5 average rating, 130 reviews
Guest favorite
A spacious bedroom features a large bed adorned with neatly arranged towels. Two bedside lamps illuminate the room, complemented by soft grey curtains and light artwork on the walls. A small plant adds a touch of greenery, enhancing the calming ambiance.
Home in San Diego

Upscale 3 Bed Oasis | Fire Pit, BBQ | Downtown SD

FamilyValueQuiet

4.96 out of 5 average rating, 190 reviews
Guest favorite
The entrance features a charming arched porch with a tiled roof and elegant railings. Two outdoor sconces flank the front door, which is framed by well-maintained landscaping with palm plants. Sunlight casts gentle shadows across the steps leading up to the door.
Home in South Park

South Park Spanish Stunner Renovated & Central

ValueLocationCleanliness

4.88 out of 5 average rating, 165 reviews
Top guest favorite
The exterior of the bungalow features a welcoming entrance with a large covered porch, flanked by vibrant palm trees and landscaped greenery. The property number is clearly displayed, and a wooden fence surrounds the yard, providing a sense of privacy.
Home in Hillcrest

Hillcrest 2 bed 2 en-suite baths garage zen garden

ValueFamilyAmenities

4.98 out of 5 average rating, 437 reviews
Top guest favorite
The entrance of a historic craftsman house is framed by lush greenery and palm trees. A set of blue steps leads to a covered porch doorway, which is adorned with a flag. Natural stones border the path, providing a welcoming approach.
Home in Hillcrest

A Charming House. Short walk to Balboa park & Zoo!

FamilyValueIndoor spaces

4.88 out of 5 average rating, 298 reviews
Top guest favorite
Home in Downtown San Diego

Walk to Gaslamp & Petco • Rooftop Spa & Game Room

LocationValueDecor

4.98 out of 5 average rating, 50 reviews

When is the best time to visit Downtown San Diego?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$42,057 GYDG$44,986 GYDG$48,962 GYDG$50,426 GYDG$49,380 GYDG$54,821 GYDG$58,378 GYDG$50,636 GYDG$45,823 GYDG$44,986 GYDG$44,777 GYDG$49,590 GYD
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