
House vacation rentals in Downtown San Diego
Find and book unique houses on Airbnb
Quick stats about house rentals in Downtown San Diego

Total vacation rentals
Explore 170 vacation rentals in Downtown San Diego

Nightly prices starting at
Downtown San Diego vacation rentals start at G$12,553 GYD per night before taxes and fees

Verified guest reviews
Over 14,860 verified reviews to help you choose

Family-friendly vacation rentals
110 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 60 rentals that welcome pets

Rentals with dedicated workspaces
80 properties have a dedicated workspace

Wi-Fi availability
160 of Downtown San Diego vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Downtown San Diego rentals

4.8 Average rating
Downtown San Diego stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated house rentals in Downtown San Diego
Guests agree: these houses are highly rated for location, cleanliness, and more.

Walk to Balboa Park and Hillcrest from an Immaculate Home
Take a stroll through the park, then unwind with a leisurely dinner under the festoon lights. Classic crown molding, hardwood floors, and pared-back tones of gray and taupe create an air of calm at this elegant haven spread out over 1500 square feet. You will find the space charming & spacious with over 1500 sq. feet. This single level property is the lower level of a historic duplex. Hardwood floors, crown molding, gas fireplace and laundry room. Street parking is usually readily available. This A+ location of Banker's Hill is NOT impacted by air plane noise. Enjoy the entire lower level duplex and use of the back yard with patio set for dining. Please note the upper tenant may also want to use this space so this area could be shared. We would love to greet you but are also fine with allowing you to access with a code on the front door. We live nearby and are happy to make suggestions for dining or things to do. Located near numerous restaurants, and Balboa Park, Hillcrest, the zoo, Downtown, Little Italy, and the Convention Center are all within 10 minutes. Be at the beach in less than 15 minutes. The bus line runs up First Ave for easy access to Downtown and Uptown. Near trolley and train station. We are within 10 minutes to the San Diego International Airport and a quick Uber ride to Downtown, Little Italy. Walk to the heart of Hillcrest, Balboa Park and the Zoo. Be at the beach in less then 15 minutes. Central location near the I-5, I-163 & I-8. Because of the hardwood floors, you will hear the footsteps above. The kitchen is well stocked if your a cook and we have an area where you can set up your laptop. wireless available and 3 smart TV's for your enjoyment. Small market less than 1 block away.
4.95 out of 5 average rating, 370 reviews
Admire Harbor Views from the Porch at a City Gem
Unwind in a cozy colorful casita in this light-filled 1920s Spanish bungalow decorated with Mexican folklorico. Take a walk into Little Italy for dinner. Or to a show at the Old Globe.What’s best, is how close you are to so much, all without needing a car. A very small single car garage is provided, think compact car. Street parking is free but challenging at times. The house is located directly below the incoming flight path. You are encouraged to read the reviews regarding this.Ideal for four.
4.95 out of 5 average rating, 512 reviews
NEW Luxury 3BR HOUSEof DT Walk Petco w/Garage AC
Located in the heart of Downtown San Diego, this unique house has been completely remodeled and re-imagined to make your stay unforgettable. Designed with the eye toward comfort and entertainment. 7 min walk Petco Park/14 min walk to Convention Center/6 min to Zoo/9 min Airport/12 min to SeaWorld/9 min to Coronado *Stunning bathrooms w/ dual showers, tub, smart glass *Full Kitchen, AC Central *SONOS Sound System, 4K TVs every room *Walk to coffee, yoga & gyms, dining, entertainment, shopping!
4.92 out of 5 average rating, 213 reviews
Little Italy Historical
This AirBNB residence is a recently fully renovated historical property in San Diego’s Little Italy community. Many say it’s one of the finest. It is only 3 short blocks from Little Italy’s vibrant India Street and its many restaurants, bars, cafes, and shops, and four from the Trolley. It’s also a short drive to San Diego’s beaches and attractions. The AirBNB unit is a ground floor private one bed/one bath suite with a living room and its own entrances. Pics and descriptions are enclosed.
4.98 out of 5 average rating, 114 reviews
Modern Surf Themed Home - Heart of Gaslamp
Step into a modern surf-themed retreat in the vibrant heart of San Diego's Gaslamp Quarter. Perfectly blending laid-back coastal vibes with sleek, urban style, this one-of-a-kind home is designed to be your getaway oasis in the middle of all the action. 7 actual beds no air mattresses or sofa-beds. This is the only 4-bedroom 4-bath for rent in all downtown San Diego. It is close to Convention Center, Petco Park, and Nightlife. This is not a party house. Person booking home must be over 25.
4.97 out of 5 average rating, 157 reviews
EpicViews | 3-Stories with Rooftop | Cortez Hill
📍 Unbeatable Central Location! Welcome to Casa Cortez Hill! This charming 3-story home features 3 bedrooms, 2 baths, and a private 4th-story rooftop deck with firepit. At 1,510 sq ft, it comfortably sleeps up to 8 guests. Centrally located—walk to Little Italy, Gaslamp, and Petco Park. Just few miles from the airport and minutes to the beach. Enjoy San Diego’s best dining, nightlife, and coastal vibes. Casa Cortez Hill is your home base for all things San Diego. We can't wait to host you!
4.99 out of 5 average rating, 148 reviews
#1 LOCATION - Rare Luxury Home in Downtown
***THE BEST RATED RENTAL IN DOWNTOWN SAN DIEGO*** Location doesn't get better than this! Right in the heart of the lively Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. Just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & Zoo! All the frills: + Prime location! 98/100 Walker Score rating + Private parking + Private Sundeck & Backyard Stay at this modern luxury home for your next trip!
4.9 out of 5 average rating, 764 reviews
Pool Oasis in Central Hillcrest by Park/Zoo
The enormous infinite edge pool floats above the jungle floor. Perched on a private canyon, this modern house is conveniently located in the heart of Hillcrest, walking distance to restaurants, bars, Balboa Park, the San Diego Zoo. Private paradise in walking neighborhood! Multiple private work spaces with treetop views. Cinema room with surround sound! NOTE: Not suitable for young children (heights, noise restrictions, breakables). NO PETS! NO PARTIES! (STRICT!). TOT# 641946.
4.92 out of 5 average rating, 185 reviews
Little Italy 2BR Loft Near Waterfront & Convention
Discover the heart of San Diego from our spacious loft in Little Italy, the culinary gem of downtown. Perfectly situated for both business and leisure travelers, you're steps away from the waterfront, convention center, and vibrant city life. Embrace the urban experience with convenience at your doorstep, including eclectic bars and restaurants. We provide a white noise machine and earplugs, though the lower floor offers a quieter retreat. Experience the best of city living!
4.83 out of 5 average rating, 228 reviews
The Island View Penthouse
⸻ Welcome to our sophisticated three-bedroom, three-bath retreat in historic Bankers Hill. Enjoy sweeping views, a full modern kitchen, and spacious living areas perfect for relaxing or entertaining. Located just minutes from Balboa Park, downtown, and San Diego’s best dining, this home blends comfort, convenience, and classic neighborhood charm. All rooms feature luxury beds from Davenport Collection. We require minimum 2-night minimum per City code, and a $299 cleaning fee.
4.98 out of 5 average rating, 133 reviews
Downtown View - 2 Story House Next to Little Italy
Two story house with 2 living rooms; 3 blocks to Little Italy restaurants, bars, & shops. Near Balboa Park, San Diego Zoo, Gaslamp, Waterfront Park & the Harbor. Museums, restaurants, theaters & nature are all nearby. Located in historic Bankers Hill, next to Interstate 5, near the airport and city center. With 2 living rooms, my house is perfect for travelers needing separate space. One parking spot is available. Extra large vehicles will have to park on the street.
4.98 out of 5 average rating, 322 reviews
🌟BEST LOCATION🌟 4BR/2BA - WALK to Little Italy 🇮🇹
Updated craftsman style home in THE BEST location! This beautiful house is close to almost everything San Diego has to offer. Only about a mile or two away from Balboa Park, the Zoo, Old Town, The Gaslamp Quarter, The Embarcadero, Hillcrest and just minutes from the airport. WALK to Little Italy in 10 minutes! Beautiful huge backyard with plenty of room to entertain. GREAT for families, or larger groups!! Sleeps 8 comfortably!
4.91 out of 5 average rating, 391 reviewsPopular amenities for Downtown San Diego house rentals
House rentals with a pool

Luxe Point Loma Oasis w/ Pool, Spa & Fire Pit
4.94 out of 5 average rating, 197 reviews
Midcentury Lux 4BR home w Pool/Spa/Cabana/Firepit
5.0 out of 5 average rating, 302 reviews
Lionhead - Private Boutique Home
4.93 out of 5 average rating, 293 reviews
Family Oasis w/ Heated Pool
4.98 out of 5 average rating, 125 reviews
Designer Luxury Rental With Pool
4.94 out of 5 average rating, 149 reviews
Your Modern Lux Pool Resort in the Heart of SD
4.9 out of 5 average rating, 188 reviews
San Diego Oasis- A Retro Retreat w/ King Size Bed!
4.92 out of 5 average rating, 102 reviews
Heart of San Diego in Old Town. Private Oasis 6
4.98 out of 5 average rating, 124 reviewsWeekly house rentals

5 Bed 2 Bath Victorian Carriage House | Parking
4.92 out of 5 average rating, 383 reviews
Hillcrest 2 bed 2 en-suite baths garage zen garden
4.98 out of 5 average rating, 435 reviews
Designer Unit w/FirePit-Petco Park, Zoo, Downtown
4.97 out of 5 average rating, 122 reviews
Bayview Paradise
4.99 out of 5 average rating, 155 reviews
1stResorts.com WATERVIEW FAMILY VILLA HOT TUB YARD
4.94 out of 5 average rating, 103 reviews
STUNNING MANSION THE BEST LOCATION & AMENITIES
4.95 out of 5 average rating, 166 reviews
South Park Spanish Stunner Renovated & Central
4.88 out of 5 average rating, 164 reviews
Ventana Vista | Ocean View | EV Charger | Designer
4.97 out of 5 average rating, 290 reviewsPrivate house rentals

Modern ❤️ of South Park, SD skyline, private patio
4.94 out of 5 average rating, 334 reviews
Lovely Victorian Home in the Heart of San Diego
4.98 out of 5 average rating, 138 reviews
Modern 3BR•Huge Private Yard•Hot Tub•8 Mins to DT
4.93 out of 5 average rating, 166 reviews
The Art House
4.95 out of 5 average rating, 165 reviews
Historic Golden Hill Post Office - 3 BR w fire pit
4.89 out of 5 average rating, 227 reviews
Sunlit 3-Story Iconic Modern Gem in North Park
4.98 out of 5 average rating, 130 reviews
4 BR/4.5 Bath 5 Minutes from Convention Center
4.95 out of 5 average rating, 475 reviews
Historic Post Office loft 4 Bed + firepit Near Zoo
4.88 out of 5 average rating, 163 reviewsWhen is the best time to visit Downtown San Diego?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$42,053 GYD | G$44,982 GYD | G$48,958 GYD | G$50,422 GYD | G$49,376 GYD | G$54,816 GYD | G$58,373 GYD | G$50,631 GYD | G$45,819 GYD | G$44,982 GYD | G$44,773 GYD | G$49,585 GYD |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Destinations to explore
- Townhouse rentals Downtown San Diego
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- Rentals with a hot tub Downtown San Diego
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- SeaWorld San Diego
- Coronado Beach
- Rosarito Beach
- LEGOLAND California
- University of California-San Diego
- Petco Park
- San Diego Zoo
- San Diego Convention Center E Ent
- San Diego Zoo Safari Park
- Pacific Beach
- San Diego State University
- Balboa Park
- Tijuana Beach
- Torrey Pines State Beach
- Mission Beach
- Las Olas Resort & Spa
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- Belmont Park
- Sesame Place San Diego
- South Mission Beach, San Diego
- Liberty Station





