
House vacation rentals in Downtown San Diego
Find and book unique houses on Airbnb
Quick stats about house rentals in Downtown San Diego

Total vacation rentals
Explore 170 vacation rentals in Downtown San Diego

Nightly prices starting at
Downtown San Diego vacation rentals start at G$12,528 GYD per night before taxes and fees

Verified guest reviews
Over 14,860 verified reviews to help you choose

Family-friendly vacation rentals
110 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 60 rentals that welcome pets

Rentals with dedicated workspaces
80 properties have a dedicated workspace

Wi-Fi availability
160 of Downtown San Diego vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Downtown San Diego rentals

4.8 Average rating
Downtown San Diego stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated house rentals in Downtown San Diego
Guests agree: these houses are highly rated for location, cleanliness, and more.

Walk to Balboa Park and Hillcrest from an Immaculate Home
Take a stroll through the park, then unwind with a leisurely dinner under the festoon lights. Classic crown molding, hardwood floors, and pared-back tones of gray and taupe create an air of calm at this elegant haven spread out over 1500 square feet. You will find the space charming & spacious with over 1500 sq. feet. This single level property is the lower level of a historic duplex. Hardwood floors, crown molding, gas fireplace and laundry room. Street parking is usually readily available. This A+ location of Banker's Hill is NOT impacted by air plane noise. Enjoy the entire lower level duplex and use of the back yard with patio set for dining. Please note the upper tenant may also want to use this space so this area could be shared. We would love to greet you but are also fine with allowing you to access with a code on the front door. We live nearby and are happy to make suggestions for dining or things to do. Located near numerous restaurants, and Balboa Park, Hillcrest, the zoo, Downtown, Little Italy, and the Convention Center are all within 10 minutes. Be at the beach in less than 15 minutes. The bus line runs up First Ave for easy access to Downtown and Uptown. Near trolley and train station. We are within 10 minutes to the San Diego International Airport and a quick Uber ride to Downtown, Little Italy. Walk to the heart of Hillcrest, Balboa Park and the Zoo. Be at the beach in less then 15 minutes. Central location near the I-5, I-163 & I-8. Because of the hardwood floors, you will hear the footsteps above. The kitchen is well stocked if your a cook and we have an area where you can set up your laptop. wireless available and 3 smart TV's for your enjoyment. Small market less than 1 block away.
ValueFamilyAir conditioning

Admire Harbor Views from the Porch at a City Gem
Unwind in a cozy colorful casita in this light-filled 1920s Spanish bungalow decorated with Mexican folklorico. Take a walk into Little Italy for dinner. Or to a show at the Old Globe.What’s best, is how close you are to so much, all without needing a car. A very small single car garage is provided, think compact car. Street parking is free but challenging at times. The house is located directly below the incoming flight path. You are encouraged to read the reviews regarding this.Ideal for four.
ValueLocationWalkability

NEW Luxury 3BR HOUSEof DT Walk Petco w/Garage AC
Located in the heart of Downtown San Diego, this unique house has been completely remodeled and re-imagined to make your stay unforgettable. Designed with the eye toward comfort and entertainment. 7 min walk Petco Park/14 min walk to Convention Center/6 min to Zoo/9 min Airport/12 min to SeaWorld/9 min to Coronado *Stunning bathrooms w/ dual showers, tub, smart glass *Full Kitchen, AC Central *SONOS Sound System, 4K TVs every room *Walk to coffee, yoga & gyms, dining, entertainment, shopping!
ValueFamilyComfort

Designer Unit w/FirePit-Petco Park, Zoo, Downtown
Welcome to our 1920's craftsman in San Diego's Best neighborhood! *Unbeatable Location! Minutes Petco Park, Downtown, Zoo, Conv Center *Washer & Dryer *Thoughtfully Renovated *Boutique hotel-like experience Fire pit, grills, and outdoor dining area! This chic apartment is located on the edge of the iconic Balboa Park, and is walkable to trendy restaurants and bars. Less than a mile from the San Diego Zoo, mins to Gaslamp Quarter, Convention center, airport, and a 10 minute drive to beaches.
FamilyLocationHospitality

#1 LOCATION - Rare Luxury Home in Downtown
***THE BEST RATED RENTAL IN DOWNTOWN SAN DIEGO*** Location doesn't get better than this! Right in the heart of the lively Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. Just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & Zoo! All the frills: + Prime location! 98/100 Walker Score rating + Private parking + Private Sundeck & Backyard Stay at this modern luxury home for your next trip!
ValueLocationParks

Pool Oasis in Central Hillcrest by Park/Zoo
The enormous infinite edge pool floats above the jungle floor. Perched on a private canyon, this modern house is conveniently located in the heart of Hillcrest, walking distance to restaurants, bars, Balboa Park, the San Diego Zoo. Private paradise in walking neighborhood! Multiple private work spaces with treetop views. Cinema room with surround sound! NOTE: Not suitable for young children (heights, noise restrictions, breakables). NO PETS! NO PARTIES! (STRICT!). TOT# 641946.
FamilyLocationPool

Little Italy 2BR Loft Near Waterfront & Convention
Discover the heart of San Diego from our spacious loft in Little Italy, the culinary gem of downtown. Perfectly situated for both business and leisure travelers, you're steps away from the waterfront, convention center, and vibrant city life. Embrace the urban experience with convenience at your doorstep, including eclectic bars and restaurants. We provide a white noise machine and earplugs, though the lower floor offers a quieter retreat. Experience the best of city living!
FamilyValueLayout

The Island View Penthouse
⸻ Welcome to our sophisticated three-bedroom, three-bath retreat in historic Bankers Hill. Enjoy sweeping views, a full modern kitchen, and spacious living areas perfect for relaxing or entertaining. Located just minutes from Balboa Park, downtown, and San Diego’s best dining, this home blends comfort, convenience, and classic neighborhood charm. All rooms feature luxury beds from Davenport Collection. We require minimum 2-night minimum per City code, and a $299 cleaning fee.
FamilyValueCondition

Downtown View - 2 Story House Next to Little Italy
Two story house with 2 living rooms; 3 blocks to Little Italy restaurants, bars, & shops. Near Balboa Park, San Diego Zoo, Gaslamp, Waterfront Park & the Harbor. Museums, restaurants, theaters & nature are all nearby. Located in historic Bankers Hill, next to Interstate 5, near the airport and city center. With 2 living rooms, my house is perfect for travelers needing separate space. One parking spot is available. Extra large vehicles will have to park on the street.
ValueLocationBeach

Luxury 7 BR Mission Hills Home with a View
Incredible 7 BR and 4.5 bath home with amazing views of downtown San Diego. Two story wrap around deck complete with two full kitchens. Complete remodel with stylish upgrades. Great open spaces and indoor / outdoor living with wrap around two story deck. On a quiet culdesac with 3 dedicated parking spaces whether you wish to enjoy a family getaway or executive retreat you will love the central location with the peaceful and tranquil views
ValueFamilyParking

New Luxury 3BR/3.5BA Point Loma Coastal One Story
*3BR 3.5BA*1,600 Sq Ft Single Story Living*Indoor Outdoor Living & Entertaining ** Three En Suite Bathrooms***3 Blocks To SD Bay***2 Sets Of W/D***6 TVS***High Speed Fiber Internet***Forced Air HVAC***Heated Outdoor Entertaining Area w BBQ***2 Assigned Parking Spots**EV Charger****10 Ft Ceilings**Italian Marble Counter Tops**8' Solid Core Mahogany Doors**Italian Porcelain Floors**Vaulted Ceilings**Kohler Black Hardware*Village Living***
FamilyValueComfort

🌟BEST LOCATION🌟 4BR/2BA - WALK to Little Italy 🇮🇹
Updated craftsman style home in THE BEST location! This beautiful house is close to almost everything San Diego has to offer. Only about a mile or two away from Balboa Park, the Zoo, Old Town, The Gaslamp Quarter, The Embarcadero, Hillcrest and just minutes from the airport. WALK to Little Italy in 10 minutes! Beautiful huge backyard with plenty of room to entertain. GREAT for families, or larger groups!! Sleeps 8 comfortably!
LocationFamilyView
Popular amenities for Downtown San Diego house rentals
House rentals with a pool

Midcentury Lux 4BR home w Pool/Spa/Cabana/Firepit
ValueLocationWalkability

Lionhead - Private Boutique Home
ValueLocationComfort

San Diego Pool House with Luxury King/Queen Suites
LocationFamilyDecor

Designer Luxury Rental With Pool
LocationFamilyGetting around

Family Oasis w/ Heated Pool
FamilyLocationQuiet

Your Modern Lux Pool Resort in the Heart of SD
ValueLocationLayout

San Diego Oasis- A Retro Retreat w/ King Size Bed!
LocationFamilyView

Modern Central SD Home w/ Pool & Spa Near Beach
ValueFamilyCheck-in
Weekly house rentals

Tranquil 4 Bedroom w/ Deck & Backyard
FamilyValueSleep quality

Condé Nast Villa | Speakeasy · Hot Tub · Sleeps 10
FamilyLocationAccuracy

Spacious House close to Petco Park and Gaslamp
ValueLocationParks

STUNNING MANSION THE BEST LOCATION & AMENITIES
LocationFamilyParks

Little Italy Historical
LocationFamilyIndoor spaces

5 Bed 2 Bath Victorian Carriage House | Parking
ValueFamilyComfort

Bayview Paradise
LocationValueView

Cheerful 2 bedroom house in heart of San Diego
FamilyValueTV
Private house rentals

Ventana Vista | Ocean View | EV Charger | Designer
LocationValueLong stay

Lovely Victorian Home in the Heart of San Diego
LocationFamilyBackyard

Top 1% | Hot Tub Oasis | Walkable North Park
FamilyLocationIndoor spaces

Central Charm in Hillcrest near Scripps Mercy
ValueFamilyParking

2. Amazing Comfort J street
ValueLocationLayout

A Charming House. Short walk to Balboa park & Zoo!
FamilyLocationHospitality

South Park Spanish Stunner Renovated & Central
FamilyLocationDecor

Convention Center | Petco Park | Free Parking
FamilyValueHospitality
When is the best time to visit Downtown San Diego?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$41,969 GYD | G$44,892 GYD | G$48,859 GYD | G$50,321 GYD | G$49,277 GYD | G$54,706 GYD | G$58,255 GYD | G$50,530 GYD | G$45,727 GYD | G$44,892 GYD | G$44,683 GYD | G$49,486 GYD |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Destinations to explore
- Townhouse rentals Downtown San Diego
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- Rentals with beach access Downtown San Diego
- Rentals with pools Downtown San Diego
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- Family-friendly rentals Downtown San Diego
- Waterfront rentals Downtown San Diego
- Rentals with a hot tub Downtown San Diego
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- Pet-friendly rentals Downtown San Diego
- Condo rentals Downtown San Diego
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- House rentals San Diego
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- House rentals United States
- SeaWorld San Diego
- Coronado Beach
- Rosarito Beach
- LEGOLAND California
- University of California-San Diego
- Petco Park
- San Diego Zoo
- San Diego Convention Center E Ent
- San Diego Zoo Safari Park
- Pacific Beach
- Balboa Park
- San Diego State University
- Tijuana Beach
- Torrey Pines State Beach
- Mission Beach
- Ocean Front Walk
- Las Olas Resort & Spa
- Oceanside City Beach
- La Misión Beach
- Moonlight State Beach
- Sesame Place San Diego
- Belmont Park
- South Mission Beach, San Diego
- Liberty Station





