Family-friendly vacation rentals in Downtown San Diego

Apartment in Downtown San Diego

A spacious living area is furnished with a floral-patterned love seat and two armchairs. Custom-built shelves house a collection of books, while a coffee table sits on a patterned rug. Bright yellow walls enhance the natural light streaming through the shuttered windows.

Trendy Studio, Natural Light - Heart of Downtown

Large studio with comfortable queen sized Murphy Bed, a love seat, private entrance and private bath. Located in Cortez Hill - walk to the nicest neighborhoods in downtown like Little Italy, Gaslamp, East Village, and the Embarcadero. There is no full kitchen, but there is a small refrigerator, small microwave, and a pot for heating water. This is an ideal space for solo travelers, couples, events at the Convention Center, Padres Games, great eateries, and the best of Downtown San Diego.

Indoor spacesKitchenDecor

4.96 out of 5 average rating, 384 reviews

Apartment in Little Italy

An expansive outdoor patio is showcased, featuring a comfortable sectional sofa with soft cushions and a stylish coffee table. Bi-folding doors connect to a modern kitchen area adorned with sleek cabinetry. The distant view reveals the San Diego coastline under a clear blue sky.

Calm Luxury Penthouse Getaway With Panoramic Views

Welcome to the most relaxing and luxurious penthouse condo in Little Italy! Featuring 2 expansive balconies with sweeping views, my condo sleeps 4-6 comfortably and is situated right in the heart of San Diego's most desirable neighborhood, Little Italy. Enjoy an area that is rich in exquisite cuisine, boutiques, patio cafés, exciting bars and local breweries. Area amenities nearby feature the famous San Diego Zoo, beautiful Balboa Park, Waterfront Park, the Convention Center and much more!

KitchenIndoor spacesGetting around

4.94 out of 5 average rating, 260 reviews

Apartment in Downtown San Diego

A vibrant urban scene features a modern skyline with a mix of high-rise buildings and palm trees. A red light rail train runs along the forefront, complementing the bustling city atmosphere and showcasing the walkability of the San Diego area.

Home away from home in Gaslamp

Welcome to San Diego and my home in the middle of it all! This location is close to the convention center, Gaslamp Quarter, Petco Park and a short drive to the famous beaches that make San Diego so sought after. The apartment is equipped with everything you'll need, a fully stocked kitchen, laundry, beach gear, you name it. Located in one of the most walkable areas of San Diego. Bars, restaurants and shopping are all just steps away. FYI this is not a quiet location, city noise is apparent.

FamilyKitchenBathroom

4.99 out of 5 average rating, 101 reviews

Home in Downtown San Diego

The exterior of the three-story home is showcased, featuring a warm-colored facade with red doors and decorative balconies. A spacious rooftop deck offers seating and striking views of the surrounding San Diego skyline. The interior layout reveals an open floor plan with comfortable furnishings and natural light.

EpicViews | 3-Stories with Rooftop | Cortez Hill

📍 Unbeatable Central Location! Welcome to Casa Cortez Hill! This charming 3-story home features 3 bedrooms, 2 baths, and a private 4th-story rooftop deck with firepit. At 1,510 sq ft, it comfortably sleeps up to 8 guests. Centrally located—walk to Little Italy, Gaslamp, and Petco Park. Just few miles from the airport and minutes to the beach. Enjoy San Diego’s best dining, nightlife, and coastal vibes. Casa Cortez Hill is your home base for all things San Diego. We can't wait to host you!

Indoor spacesKitchenAccess

4.99 out of 5 average rating, 150 reviews

Apartment in Downtown San Diego

Artifact Inn - Historic Deluxe Studio in Downtown

The Artifact Inn professionally managed by NOVIQ. Unwind with ease in this chic Gaslamp studio offering a queen bed, air mattress, Smart TV, and free WiFi. Cook meals in the full kitchen, refresh with in-unit laundry, and enjoy climate control with central AC. With thoughtful touches and professional cleaning, this stylish retreat provides both comfort and security. Perfectly situated near Petco Park and top attractions, it’s ideal for those seeking a central and vibrant San Diego escape.

KitchenFamilyLocation

4.9 out of 5 average rating, 117 reviews

4.93 out of 5 average rating, 411 reviews

An exterior view of a bungalow showcases a unique architectural style with smooth, rounded walls. Soft lighting highlights the inviting entrance, surrounded by potted plants. The paved pathway leads to a wooden fence, adding to the property's privacy, all under a clear evening sky.

Bungalow in Little Italy

Gorgeous 2Bd Corner Bungalow in Little Italy

Little Italy Bungalows are located in the heart of San Diego’s most popular restaurant and entertainment district, Little Italy. Just one block from India Street, Farmer’s Market, and minutes from downtown, Balboa Park, airport, and harbor & beaches. This is a delightful neighborhood, steeped in local history and culture, and popular for dining and exploring. Little Italy Bungalows is perfect for couples, families, business travelers, convention-goers, single travelers and adventurers.

FamilyKitchenNearby

Townhouse in Bankers Hill - Park West

An outdoor seating area features four white Adirondack chairs arranged around a circular concrete fire pit. Lush greenery surrounds the space, and the home's exterior showcases a blend of gray and blue siding under the evening sky.

City View Banker's Hill

A beautifully renovated 2-bedroom, 1.5-bathroom craftsman-style duplex is perfectly situated in the heart of Bankers Hill. The perfect blend of classic craftsmanship and modern amenities in this beautifully restored home. Minutes away from San Diego's top attractions, including Balboa Park, Little Italy, and the vibrant Gaslamp Quarter. Two comfortable bedrooms provide a peaceful retreat. Fully equipped kitchen with new appliances. A perfect place to enjoy all that San Diego has to offer.

KitchenIndoor spacesLocation

4.92 out of 5 average rating, 114 reviews

4.9 out of 5 average rating, 768 reviews

A spacious living area is characterized by high ceilings with exposed beams and large windows allowing natural light. A comfortable gray sofa, adorned with colorful cushions, is paired with a bright yellow accent chair. A modern coffee table and entertainment unit complete the inviting space.

Home in Little Italy

#1 LOCATION - Rare Luxury Home in Downtown

***THE BEST RATED RENTAL IN DOWNTOWN SAN DIEGO*** Location doesn't get better than this! Right in the heart of the lively Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. Just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & Zoo! All the frills: + Prime location! 98/100 Walker Score rating + Private parking + Private Sundeck & Backyard Stay at this modern luxury home for your next trip!

KitchenIndoor spacesBathroom

Townhouse in Little Italy

The living room features soaring ceilings and a wall of windows, allowing ample natural light to illuminate the space. Comfortable seating arrangements are complemented by modern art pieces on the walls. A sleek fireplace and stylish furniture create a welcoming ambiance, framed by elegant decor.

Kettner Row | Staycation-Featured Icon

Welcome to Kettner Row, a rare architectural masterpiece featured on Staycation Sports, an Emmy-winning show on the Destination Channel! Located in the heart of Little Italy—one of San Diego’s most desirable neighborhoods—and designed by renowned architect Jonathan Segal, FAIA. This detached row home is situated in the award-winning Little Italy Neighborhood Developers block (LIND). This modern home features dual master suites, a high-end designer kitchen, and luxurious spa bathrooms.

Indoor spacesFamilyHospitality

4.95 out of 5 average rating, 168 reviews

Loft in Downtown San Diego

Downtown San Diego Loft | Best Walkable Location

Stay steps from Petco Park in a thoughtfully designed two-story loft in the heart of downtown San Diego. Designed by award-winning architect Jonathan Segal, this modern space features high ceilings, a calm open layout, and a private balcony with city views. Enjoy a queen bed upstairs and a sofa bed in the living room, plus a full kitchen, washer/dryer, and easy self check-in. A more spacious, private, and relaxed alternative to typical downtown hotel stays.

Indoor spacesKitchenGetting around

4.94 out of 5 average rating, 520 reviews

4.97 out of 5 average rating, 101 reviews

A green sofa is positioned against a wall adorned with an eclectic gallery of framed artworks, including abstract designs, floral patterns, and clock. Textures vary with a plush, white throw pillow placed at the center, providing a cozy accent against the diverse art pieces.

Condo in Little Italy

Little Italy King Suite

A luxurious 1b/1b condo . The spacious living area includes a flat screen TV and large courtyard viewing window laced with marble tile. The peaceful bedroom features a king sized bed, SMART flat screen TV, and ample storage space. Experience San Diego in this prime Little Italy location . Walking distance to Water Front Park, Seaport Village, Embarcadero, and all of Little Italy. *No Parking Available After September 1, 2026.

FamilyKitchenCleanliness

4.98 out of 5 average rating, 131 reviews

A modern, two-story beach house is displayed, featuring a light-colored exterior and a welcoming front porch. Two white chairs sit on a small patio, surrounded by landscaped gardens with green shrubs and flowering plants. The blue front door adds a vibrant touch.

Home in Ocean Beach

Bright & Modern OB Getaway

This newly built, 2 bedroom/2 bath, is the bright & airy, modern & stylish beach getaway you've been looking for! You'll be located 2 blocks from the beach, and are walking distance to a variety of different restaurants, coffee shops, yoga studios, and nightlife options. The rooftop deck provides an amazing panoramic view for catching sunsets, and even the Sea World fireworks show. Bikes and beach gear ready for use!

Indoor spacesKitchenAmenities

Popular amenities for Downtown San Diego family-friendly rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Family-friendly home rentals with a hot tub

Guesthouse in Mission Hills

A spacious living area features a large sectional sofa adorned with decorative pillows, complemented by a wooden coffee table. A vibrant wall art piece with colorful surfboards is displayed above the couch, while natural light fills the room through expansive windows.

Beautiful Historic Home and Gardens Near Downtown!

FamilyIndoor spacesLocation

4.97 out of 5 average rating, 300 reviews

4.92 out of 5 average rating, 186 reviews

An inviting outdoor area features a modern infinity pool, surrounded by lush greenery. Comfortable seating in blue upholstery invites relaxation, while sun loungers provide additional spaces for sunbathing. The serene atmosphere is enhanced by the tranquility of nature in the background.

Home in Hillcrest

Pool Oasis in Central Hillcrest by Park/Zoo

Indoor spacesFamilyCheck-in

4.94 out of 5 average rating, 198 reviews

Luxe Point Loma Oasis w/ Pool, Spa & Fire Pit

Indoor spacesKitchenOutdoor spaces

4.96 out of 5 average rating, 181 reviews

The poolside area features a well-maintained saltwater pool reflecting the colors of the sunset. Comfortable seating arrangements, including lounge chairs and a cozy fire pit, are visible. Large umbrellas provide shade, and lush greenery adds to the serene ambiance.

Guesthouse in La Mesa

Vacation Paradise-Heated Pool+Hot Tub+FirePit+EV

Indoor spacesFamilyAccuracy

Superhost

4.9 out of 5 average rating, 126 reviews

Sleeps 16 | Hot Tub & Fire Pit | 5BR Reunion Home

FamilyIndoor spacesSleep quality

Home in University Heights

A well-lit bedroom features a spacious bed with neutral bedding and striped pillows. Natural light enters through glass doors leading to a semi-private patio. A textured area rug and a potted plant add subtle warmth to the wood flooring.

Cozy University Heights Cottage

KitchenFamilyCheckout

4.87 out of 5 average rating, 126 reviews

5.0 out of 5 average rating, 303 reviews

A private outdoor area features a heated pool surrounded by lush green grass and modern loungers. An inviting fire pit is centrally located, with two stylish chairs positioned nearby. The backdrop includes well-maintained shrubbery and tall trees, enhancing the tranquil ambiance.

Home in Serra Mesa

Midcentury Lux 4BR home w Pool/Spa/Cabana/Firepit

KitchenFamilyCheckout

An open floor plan connects the living area to the kitchen, with a dining table set for four. A large window allows natural light to illuminate the space, while a modern TV is mounted on the wall. Comfortable seating is arranged nearby.

4.94 out of 5 average rating, 103 reviews

1stResorts.com WATERVIEW FAMILY VILLA HOT TUB YARD

FamilyIndoor spacesAccess

Family- and pet-friendly home rentals

Bungalow in Greater North Park

The inviting entrance features a covered porch adorned with a vibrant yellow door. Succulents and greenery enhance the landscape, complemented by a palm tree nearby. The porch area includes seating, providing a welcoming atmosphere for relaxation.

The Cozy Craftsman

Indoor spacesKitchenParking

4.96 out of 5 average rating, 186 reviews

Townhouse in Downtown San Diego

The exterior of the townhouse presents a modern style, with a vibrant blue and red facade complementing the concrete structure. Large windows allow for natural light, while landscaped greenery adds a touch of nature. Two parked cars are visible along the street.

Modern 3-story Townhome|Free Parking|Walk to Petco

FamilyKitchenAmenities

4.81 out of 5 average rating, 272 reviews

Home in Greater North Park

Urban Greenhouse

Indoor spacesFamilyHeating

4.99 out of 5 average rating, 206 reviews

Superhost

A bright living area features a leather sofa and a rattan chair positioned beside a light-colored coffee table. Large windows allow natural light to fill the space, showcasing a minimalist decor style. A framed art piece and potted plants add a touch of greenery.

Townhouse in Little Italy

Contemporary, Fully Renovated Loft in Little Italy

FamilyIndoor spacesLaundry

4.79 out of 5 average rating, 218 reviews

Condo in Downtown San Diego

A cozy living area features a blue couch adorned with decorative pillows against a stylish brick wall. Natural light streams through a large window, highlighting a round coffee table in front of a comfortable seating arrangement. A small plant adds a touch of greenery.

Walk 2 Gaslamp & Petco; King bed, Parking/Patio!

KitchenIndoor spacesParks

4.93 out of 5 average rating, 454 reviews

4.96 out of 5 average rating, 164 reviews

A well-equipped kitchen features a charming wooden island with bar stools, surrounded by modern appliances. Light streams through multiple windows, illuminating the cozy living area visible in the background. The warm tones of the wood beams and flooring enhance the welcoming atmosphere.

Home in Mission Hills

Beautiful Canyon Cottage located on a huge lot

KitchenIndoor spacesDecor

Bungalow in Mission Hills

A spacious bed with a striped comforter and two plush pillows occupies the center of the room. Soft bedside lamps provide warm lighting, while a framed artwork hangs on the wall above the bed. Two small, elegant stools are positioned beside the bed.

Quiet studio: King bed, AC, Washer

FamilyKitchenAir conditioning

4.8 out of 5 average rating, 569 reviews

4.99 out of 5 average rating, 155 reviews

Bayview Paradise

Indoor spacesKitchenAir conditioning

Family-friendly home rentals with a pool

A spacious backyard is showcased with a glistening pool surrounded by a concrete deck. Green grass offers a soft contrast, while lounge chairs and a shaded seating area are positioned for relaxation. String lights illuminate the space, enhancing the outdoor ambiance during twilight.

4.95 out of 5 average rating, 110 reviews

San Diego Pool House with Luxury King/Queen Suites

FamilyIndoor spacesOutdoor spaces

4.94 out of 5 average rating, 151 reviews

A living room features a luxury hanging chair suspended from the ceiling. Natural light filters through sheer curtains, illuminating a cozy seating area with a plush sofa and wooden coffee table. A 50” television is mounted above an elegant fireplace, enhancing the room's comfort.

Home in City Heights

Designer Luxury Rental With Pool

Indoor spacesFamilyHot tub

4.98 out of 5 average rating, 125 reviews

Home in Normal Heights

Private Heated Pool | Sleeps 10

KitchenFamilyTV

A dining area is highlighted by a round wooden table surrounded by six wooden chairs. A cozy blue sofa is positioned nearby, with large glass doors opening to a pool area. Natural light enhances the space, complemented by a modern pendant light overhead.

4.92 out of 5 average rating, 102 reviews

San Diego Oasis- A Retro Retreat w/ King Size Bed!

Indoor spacesFamilyLocation

4.89 out of 5 average rating, 223 reviews

A view of the inviting swimming pool surrounded by a spacious patio. Natural rock elements and vibrant landscaping enhance the outdoor area. The multi-level deck is visible, offering seating options and picturesque canyon surroundings under a clear blue sky.

Home in La Mesa

The Queen House

Indoor spacesFamilyValue

4.93 out of 5 average rating, 293 reviews

A vibrant heated pool is surrounded by minimalistic landscaping, featuring tall cacti and a clean white fence. Soft lounge chairs are positioned nearby for relaxation. The clear water reflects the blue sky, creating a refreshing setting for leisure and enjoyment.

Home in Mission Hills

Lionhead - Private Boutique Home

FamilyKitchenAmenities

4.92 out of 5 average rating, 131 reviews

A spacious outdoor patio showcases a private pool and hot tub, surrounded by comfortable seating and a fire pit. An activity area features games such as foosball and cornhole, with lounge chairs positioned for relaxation. Lush green landscaping complements the inviting space.

Home in Bay Park

Modern Central SD Home w/ Pool & Spa Near Beach

FamilyKitchenGetting around