
House vacation rentals in Des Moines
Find and book unique houses on Airbnb
Top-rated house rentals in Des Moines
Guests agree: these houses are highly rated for location, cleanliness, and more.

MidCentury, technicolor Ranch w/yard, w+d, parking
- Ranch home in Des Moines' friendly Beaverdale neighborhood - Steps from grocery store, ice cream shop+dining - Blocks to more dining+shops - Less than 5 minutes from Drake University - Around 10 minutes from downtown, Des Moines, Arts Center, parks - Easy access within 15 minutes to suburbs - 1000+ feet with open living, dining and kitchen, 2 beds, 1 bath, laundry and on-site parking - Outdoor front porch, back patio+fire pit - Perfect for a family or two couples ***Send your special requests!

Heartland BNB~Hot Tub~Sauna~fire table~2 kings
Comfort and convenience await your arrival at this centrally located home just minutes from downtown Des Moines and next to Ingersoll nightlife. This home has been newly renovated and designed for traveling families and business professionals alike. Soak away the stress in the 7 person hot tub or sweat it all out in the outdoor 5 person sauna! Grill on the patio and relax by the fire, before going to sleep in 2 very stylish and comfortable king bedrooms located on the main floor. Book Now!!

Gray Manor
Your family will be close to everything when you stay at this centrally-located home in West Des Moines, just off I-35. A bike trail leading to parks and local businesses runs through the backyard. With comfortable furnishings, and spacious rooms it's perfect for gathering with friends and family. Mere minutes from West Glen Town Center or Jordan Creek Mall! During your stay you'll have access to 4 bedrooms and 4 baths, a fully equipped kitchen, spacious living rooms, and large deck with grill.

Effortless Landing near Airport
Welcome to the Effortless Landing! Our super clean and comfy, Boho style retreat. Private keyless entry with off street parking. Enjoy a queen bed, additional pull out queen bed in the couch, great local coffee, & all the amenities like fiber wifi, TV, full kitchen, & laundry. Add that to the wonderful surroundings of the city of Des Moines, in a quiet, centrally located neighborhood. Conveniently located 4 minutes from the Des Moines International Airport, & 7 minutes to Downtown Des Moines!

Cozy Historic Escape
This comfortable bungalow is stylish with historic charm. The front porch is perfect for morning coffee. The main living space has original hardwood floors and classic brick fireplace with craftsman style built-ins. The house also has fenced in backyard with patio for enjoying temperate days. It is centrally and conveniently located close to Des Moines Playhouse, ~6 minutes from Casey’s Center and Downtown Des Moines, ~13 minutes to Jordan Creek Town Center, and ~15 minutes to DSM Airport.

Peaceful Setting & Modern Style
Escape the hustle and bustle of the city and retreat to your own private oasis with this charming 2 Bedroom Airbnb. The house provides present-day amenities while still honoring the original 1930s character. You’ll enjoy a new and sparkling clean kitchen, complete with all the appliances and utensils you need. The bathroom, laundry, dining room, reading nook and living room have all been beautifully updated as well, ensuring that you'll feel right at home from the moment you arrive.

The Carol Anne-Charming 2bd/2ba Victorian near DT!
This Victorian-era duplex is the perfect mix of Victorian and modern for all the comforts of home. Perfect for quick or extended trips. Location can't be beat: Walking distance to Drake University. Minutes by car to downtown, hospitals, Ingersoll district and proximity to I-235 gets you anywhere in the city. Off street parking/electronic locks make check-in a easy. 2 large bedrooms w/queen beds, 2 bathrooms, kitchen, laundry, closets, and more making it ideal for multiple guests!

Luxury 4 BR Mid-Century Modern home
Mid-Century Modern home unlike any other! This home was built by an architect who designed it with such quality and appeal that you will be amazed. Inside, an open layout allows a seamless flow where multiple entertainment spaces beckon. A fabulous location means you are only moments away from some of Des Moines’ best attractions. This home sits less than 10 minutes from downtown and close to biking trails, putting you within blocks of the city’s many restaurants, bars and shops.

Cozy Spa Home Close to Downtown
Enjoy the feeling of a cozy home while you visit Des Moines! This wonderful home is close to downtown, bike trails, and Riverview park where you can walk the Des Moines river. Lots of light, beautiful fenced backyard with porch, fire pit, and large charcoal grill! Full kitchen with Everything you need to cook an amazing meal. Bathroom with a large double head shower, and large soaking tub. Hulu, Netflix, and Amazon are set up on three televisions. Washer and dryer for your use!

Newly Remodeled Home with Walk-In Shower
My home is located in a safe and quiet neighborhood of Ankeny with a 16 min. drive to downtown Des Moines and Wells Fargo Arena. The high trestle trail is about 8 blocks away with a nice park 1 block away. The highlight of my home is the newly remodeled bedrooms and bathroom. There are queen beds in each of the bedrooms. The guest bed is brand new. The living room has a 55” LG OLED 4k TV with a PlayStation 5. I have high-speed cable internet with cable through slingTV.

Winter Stay by Ingersoll Ave & Drake Univ
Cozy, winter-ready home one block from Ingersoll Ave and minutes from Drake University. Enjoy fast Wi-Fi, a dedicated workspace, comfortable beds, and a fully equipped kitchen for warm nights in. Walk to Ingersoll’s restaurants and coffee shops, with easy access to Downtown DSM and Drake. Self check-in and easy parking make this ideal for remote workers, business travelers, families, and extended winter stays. ✨ Weekly and monthly winter discounts available.

White Oak Hillside Oasis
Our 3 bedroom hilltop 1950’s home with wonderful views of the capital and city of Des Moines is the perfect place for your stay. Nestled just south of downtown in a quiet historic Italian neighborhood, you are within walking distance from a world class brewery, bars, restaurants and miles of walking and biking trails surrounding Gray’s Lake. We are within a few miles of everything else that the downtown area of Des Moines has to offer!
Popular amenities for Des Moines house rentals
House rentals with a pool

New Arrival Peaceful Comfort Calm & Private

Comfortable and Spacious Five Bedroom Home

Urbandale Oasis

Ankeny Stay | Gym | Game Room | Spa | BBQ | I-35

Sleeps 16/GameRM/Pool/Hot tub/Large backyard/Pets

Summer House DSM

Urban Oasis with Pool & Hot Tub

Grimes Getaway with pool
Weekly house rentals

Charming Remodeled Home

Garden Retreat Near Downtown, Botanical Immersion

The little CABIN escape

The Draper-MCM Spacious Ranch minutes to it all

Waterbury Bungalow

Entire Bungalow in Convenient/Central Location!

Easy Des Moines Location Close to Restaurants

Spacious Home, 2 Car Garage, Fast WiFi, Fireplace
Private house rentals

Des Moines Bungalow in Drake University Area

Retro 2 Bedroom APT in Waukee, IA

Cozy Cute Bungalow

Charlie's Place

Stunning Suburban Home in Quiet Neighborhood

Modern 3BR Near Drake + Downtown | Spacious & Cozy

Kathy's Crib | 3BR Retro Style

Warm and inviting ranch
When is the best time to visit Des Moines?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$21,328 GYD | G$22,374 GYD | G$22,792 GYD | G$24,047 GYD | G$25,719 GYD | G$27,183 GYD | G$27,183 GYD | G$28,229 GYD | G$24,674 GYD | G$22,792 GYD | G$23,001 GYD | G$22,583 GYD |
| Avg. temp | -5°C | -3°C | 4°C | 11°C | 17°C | 22°C | 24°C | 23°C | 19°C | 12°C | 4°C | -2°C |
Quick stats about house rentals in Des Moines

Total vacation rentals
Explore 420 vacation rentals in Des Moines

Nightly prices starting at
Des Moines vacation rentals start at G$4,182 GYD per night before taxes and fees

Verified guest reviews
Over 24,250 verified reviews to help you choose

Family-friendly vacation rentals
300 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 170 rentals that welcome pets

Rentals with dedicated workspaces
250 properties have a dedicated workspace

Wi-Fi availability
410 of Des Moines vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Des Moines rentals

4.8 Average rating
Des Moines stays are highly rated by guests—averaging 4.8 out of 5!
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