House vacation rentals in Des Moines

Find and book unique houses on Airbnb

Top-rated house rentals in Des Moines

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Top guest favorite
A vibrant living room features a curvy orange couch, complementing a playful area rug with geometric patterns. A glass window allows natural light to illuminate the space, highlighting the eclectic decor on a nearby shelf. Seating includes a striped chair and a coffee table.
Home in Beaverdale
4.96 out of 5 average rating, 315 reviews

MidCentury, technicolor Ranch w/yard, w+d, parking

- Ranch home in Des Moines' friendly Beaverdale neighborhood - Steps from grocery store, ice cream shop+dining - Blocks to more dining+shops - Less than 5 minutes from Drake University - Around 10 minutes from downtown, Des Moines, Arts Center, parks - Easy access within 15 minutes to suburbs - 1000+ feet with open living, dining and kitchen, 2 beds, 1 bath, laundry and on-site parking - Outdoor front porch, back patio+fire pit - Perfect for a family or two couples ***Send your special requests!

Top guest favorite
The kitchen features classic wooden cabinetry and retro-style appliances, including a pale cream refrigerator. A patterned backsplash complements the checkered floor, while shelves display colorful dinnerware. Natural light fills the space, enhancing the inviting atmosphere for cooking and gathering.
Home in Ankeny
4.96 out of 5 average rating, 191 reviews

Historic Home on 4 Acres - Hot Tub, Pool, Tiki Bar

Our 1948 vacation home is on 4 acres & boasts 3 bedrooms, 3 full baths, 2 half baths, Bridal Suite (4th bedroom), 70s TV/Game Room, Tiki Bar, & Children's Playroom. Outside we have a pool (guaranteed to be open 5/26 - 9/5) & hot tub (year round). Located 15min away from Downtown DSM & a mile away from a grocery store/restaurants. Up to 2 dogs allowed for an additional fee. ***Events/photo shoots are allowed with written permission only and will be an added fee. No events larger than 25 total.***

Guest favorite
A hot tub is highlighted against a wooden privacy screen, with several spa robes hanging nearby. Soft lighting adds warmth to the scene, while a serene sunset enhances the inviting ambiance of the outdoor space.
Home in Des Moines
4.97 out of 5 average rating, 161 reviews

Heartland BNB~Hot Tub~Sauna~fire table~2 kings

Comfort and convenience await your arrival at this centrally located home just minutes from downtown Des Moines and next to Ingersoll nightlife. This home has been newly renovated and designed for traveling families and business professionals alike. Soak away the stress in the 7 person hot tub or sweat it all out in the outdoor 5 person sauna! Grill on the patio and relax by the fire, before going to sleep in 2 very stylish and comfortable king bedrooms located on the main floor. Book Now!!

Top guest favorite
A vibrant game room displays a colorful mural of Des Moines and is equipped with playful lighting. A green turf floor sets the scene, complemented by a pink door and seating. Tables are available for games, while a vending machine adds convenience.
Home in Windsor Heights
5 out of 5 average rating, 155 reviews

Sassy, Fun, Adult Getaway! Gameroom!

Prof. designed w/feminine sass, this space has so many details to make you smile! From the cuss word coffee bar to the game room, to the aromatic scent bar to the adult themed card/board games, to the choice of soft cheetah print robes & luxurious throw blankets, no detail has been left out. Walking dist. to restaurants, bars, coffee shops, grocery stores, a spa/nail place & easy access to the bike trails & I235. 10 mins to downtown DSM or the nightlife of West Glen. Super safe, quiet nbrhood.

Guest favorite
A dining area is highlighted by a round glass table surrounded by four upholstered chairs. Natural light filters through two large windows, enhancing the cozy atmosphere. A decorative circular mirror adorns one wall, while hardwood flooring adds warmth to the space.
Home in Des Moines
4.9 out of 5 average rating, 133 reviews

Drake neighborhood cottage

Great location, close to Drake University (less than 2 miles). Two Master, King bed bedrooms each with newly renovated bathrooms, with beautiful tile showers and smart toilets. This is a cozy home that is perfect for four adults, or a family of four. Newly remodeled kitchen with new refrigerator, gas range and dishwasher. Hardwood floors throughout the home, with tiled kitchen and baths. Conveniently located within a short walk to the Waveland Cafe (300 ft), a favorite breakfast spot.

Guest favorite
A spacious living area features a billiards table, a modern wood fireplace, and a casual seating arrangement. Light wood beams enhance the ceiling, while large windows allow natural light to fill the space. A dining area with stylish bar stools is visible in the background.
Home in Urbandale
4.92 out of 5 average rating, 190 reviews

RARE Mid-Mod Home. Spacious inside-and-out.

Don't miss your chance at this unique mid-century modern home located in the heart of Des Moines where you'll be just minutes from many local restaurants, bars and area attractions. Entertain your guests with 3,600sf of open-concept mid-century living while enjoying all the amenities this house has to offer! Relish in billiards indoors or escape outdoors for yard games, grilling or an evening bonfire. This newly remodeled 4 bed, 2.5 bath property has everything you need on your next vacation.

Top guest favorite
Home in Des Moines
4.98 out of 5 average rating, 166 reviews

Walkable Neighborhood Close to BEST Restaurants

Welcome to your home in Des Moines! Enjoy this comfortable historic house that is in a PRIME location in the top area of the metro. Our neighborhood is walkable and family friendly yet close enough to get to downtown for events with a short 5 minute drive. We are one block away from the award winning fine dining spot- Oak Park, and another block from the brand new historically updated dinner/show theater plus right off the bike trail system. Feel at ease with a large corner lot & fenced yard!

Guest favorite
An open-concept living area features a cozy dining table with four chairs, complemented by a floral-patterned refrigerator. Two comfortable armchairs are positioned near a light-colored rug, while natural light illuminates the wood-tone cabinets and kitchen space in the background.
Home in Des Moines
4.86 out of 5 average rating, 178 reviews

Effortless Landing near Airport

Welcome to the Effortless Landing! Our super clean and comfy, Boho style retreat. Private keyless entry with off street parking. Enjoy a queen bed, additional pull out queen bed in couch, local coffee, & all the amenities like fiber wifi, TV, linens, full kitchen, & laundry. Add that to the wonderful surroundings of the city of Des Moines, in a quiet, centrally located neighborhood. Conveniently located 4 minutes from the Des Moines International Airport, & 7 minutes to Downtown Des Moines!

Top guest favorite
The living space features a modern gray sectional sofa complemented by a green armchair. A coffee table rests on a patterned rug. Two floral artworks adorn the wall, while warm lighting is provided by standing lamps. Natural light enters through multiple windows.
Home in Des Moines
4.95 out of 5 average rating, 372 reviews

Cozy Historic Escape

This comfortable bungalow is stylish with historic charm. The front porch is perfect for morning coffee. The main living space has original hardwood floors and classic brick fireplace with craftsman style built-ins. The house also has fenced in backyard with patio for enjoying temperate days. It is centrally and conveniently located close to Des Moines Playhouse, ~6 minutes from Casey’s Center and Downtown Des Moines, ~13 minutes to Jordan Creek Town Center, and ~15 minutes to DSM Airport.

Top guest favorite
An inviting outdoor space features a spa with colorful lighting and a fire pit surrounded by seating. The interior showcases a cozy living area with a comfortable couch, a staircase leading to the upper level, and a game room with arcade gaming options.
Home in Des Moines
4.98 out of 5 average rating, 258 reviews

The Cow Tipper: Hot Tub • Game Room • Fire Pit

Welcome to The Cow Tipper! Near the heart of Downtown Des Moines sits this historic, fully remodeled, 4 bed & 2 bath home that can sleep up to 10 guests. Key offerings: - 6 person SPA - Fire-pit (bring your own wood) - Propane Grill - Game room with a Wii & Arcade - Large kitchen w/cooking essentials - Fast WIFI & Smart TVs in every room Within two miles of the Iowa Event Center, Casey's Center & Hospitals. 10min from the Airport. Walking distance to local restaurants, shops and parks

Top guest favorite
A warm living area features a brown leather sofa with decorative blue pillows, positioned next to a round coffee table on a soft area rug. A blue armchair complements the seating arrangement, and natural light enters through nearby windows. Archways lead into the adjoining rooms.
Home in Des Moines
4.99 out of 5 average rating, 236 reviews

Peaceful Setting & Modern Style

Escape the hustle and bustle of the city and retreat to your own private oasis with this charming 2 Bedroom Airbnb. The house provides present-day amenities while still honoring the original 1930s character. You’ll enjoy a new and sparkling clean kitchen, complete with all the appliances and utensils you need. The bathroom, laundry, dining room, reading nook and living room have all been beautifully updated as well, ensuring that you'll feel right at home from the moment you arrive.

Top guest favorite
A balcony view reveals a vibrant sunset casting shades of pink and orange across the sky. Silhouetted trees frame the scene, with distant buildings emerging in the background. A round glass table with colorful cushions offers a place to enjoy the view.
Home in Des Moines
4.97 out of 5 average rating, 187 reviews

Woodland Heights hist. district house on the hill.

Beautiful historic duplex house in the heart of woodland heights. Walking distance to downtown and next to Ingersoll avenue which is full of shops, bars, restaurants and more. Our place allows 2 parking spots on site with a side entrance to your upstairs Airbnb. The 800+ sq ft space includes a private kitchen, bathroom, bedroom, living room, and balcony with views of downtown. Picnic table and grassy area below balcony can be used on those nice Iowa days.

Popular amenities for Des Moines house rentals

When is the best time to visit Des Moines?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$23,011 GYDG$24,057 GYDG$24,685 GYDG$24,057 GYDG$25,731 GYDG$27,195 GYDG$27,195 GYDG$28,241 GYDG$24,685 GYDG$24,685 GYDG$23,848 GYDG$24,685 GYD
Avg. temp-5°C-3°C4°C11°C17°C22°C24°C23°C19°C12°C4°C-2°C

Quick stats about house rentals in Des Moines

  • Total vacation rentals

    Explore 420 vacation rentals in Des Moines

  • Nightly prices starting at

    Des Moines vacation rentals start at G$4,184 GYD per night before taxes and fees

  • Verified guest reviews

    Over 25,390 verified reviews to help you choose

  • Family-friendly vacation rentals

    300 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 190 rentals that welcome pets

  • Rentals with dedicated workspaces

    250 properties have a dedicated workspace

  • Wi-Fi availability

    410 of Des Moines vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Des Moines rentals

  • 4.8 Average rating

    Des Moines stays are highly rated by guests—averaging 4.8 out of 5!

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