Vacation rentals in Rochester

A stone path winds through a well-maintained garden, illuminated by soft string lights among the trees. Lush greenery and a hint of landscaping are visible, providing a serene and inviting outdoor retreat in the evening ambiance.

4.93 out of 5 average rating, 160 reviews

Woodland Retreat, Full private walkout lower level

Peaceful retreat down gravel driveway 15 min from Mayo Clinic. Enjoy your own apartment with private backyard walkout entrance to the lower level of our home. You will have a bedroom, living area, kitchenette with mini fridge, microwave and toaster oven (no conventional stove/oven), bathroom w/ tub & shower, pingpong table, laundry, and patio with fire ring. You may hear piano music weekday afternoons, since I give lessons (usually 3-6 pm; a bit earlier in summer) NEW HEATED FLOORS w/thermostat

Superhost

4.85 out of 5 average rating, 239 reviews

St. Augustine’s Flat @ St. Marys Mayo Clinic!

St Augustine Flat is the best place in town to stay. Unmatched location and space, save $$. Located in the prestigious “Pill Hill” walking distance to all of downtown Rochester, 1 block from St. Marys Hospital (in the background of pic). From St Marys catch the free Mayo Shuttle to other Mayo locations. Beautiful hardwood floors, 1 bedroom with walk-in closet, full bath, Kitchen, Fast WiFi, Smart Tv. The space is upstairs. The stairs are steep with narrow tread! I look forward to hosting you!

A cozy bedroom features a spacious bed with neatly arranged pillows and a navy throw blanket. Two lamps illuminate the nightstands flanking the bed. Wall art and a large mirror enhance the inviting atmosphere, while natural light filters in through nearby windows.

4.93 out of 5 average rating, 160 reviews

Home for the Traveler, a walk to St. Mary's

This place is located near the heart of Rochester, within blocks of St. Mary's hospital, very peaceful, cozy and private. A lower-level unit in an older home, plenty of windows and light, and includes a gorgeous bedroom with a fireplace, a full kitchen, a reading room, and a clean, updated bathroom. This home is also close to the Apache mall, the Canadian Honker and other local restaurants, coffee shops, and the walking/biking trail system. There is also Wi-Fi, laundry, and parking on-site.

A tranquil outdoor space features a winding gravel pathway surrounded by native plants, including grasses and shrubs. Large stones are positioned along the path, complementing the natural landscape, while a wooden fence provides privacy and defines the area.

4.94 out of 5 average rating, 233 reviews

Euro House, Bright! Near Mayo-Single Family Home

Welcome to our private single family home designed by local architect Harold Crawford, located in a quiet neighborhood close to the Mayo Clinic, parks, & restaurants. The backyard is a master gardeners dream space, filled with native plants & outdoor seating. 2 queen bedrooms & 2 full baths. Off street parking for 1 vehicle, plenty of street parking. Wi-Fi, cable, smart TV's, washer & dryer included. Pet free, Clean and Modern home away from home. 5 minutes / .9 miles from Mayo Clinic!

A cozy outdoor patio space features two comfortable chairs facing a small blue table. A colorful patterned rug adds vibrancy, while potted plants and a flowering arrangement provide natural beauty. The backdrop consists of a metal fence and lush greenery, enhancing the sense of privacy.

4.87 out of 5 average rating, 341 reviews

Mayo Downtown's Prairie Home Retreat

Nestled in a serene corner, this home offers a perfect blend of tranquility and accessibility; being near the Mayo campus and Rochester's key attractions. Enjoy comfortable beds, a well-appointed kitchen, and a fenced yard with patio gardens. It's an excellent spot for family bonding, featuring three smart TVs, rapid Wi-Fi, and a variety of indoor and outdoor entertainment options. We strive to accommodate flexible check-in/check-out arrangements whenever feasible. Rollator accessible.

A two-story house is presented, featuring a light gray exterior and white trim. Multiple windows are visible, showcasing symmetry and providing ample natural light. A green lawn surrounds the home, with a pathway leading to the porch. Tall trees offer additional greenery nearby.

4.88 out of 5 average rating, 162 reviews

NEW: Calming main floor retreat near Mayo Clinic

• Enhanced cleaning protocols due to COVID • Fully renovated apartment in winter 2019 • Main floor apt in quiet 4plex • 550 square feet with refinished hardwood floors throughout • La-Z-Boy power recline loveseat with power headrests and USB ports. Both sides also rock. • 65" Smart TV with DirecTV • Free off-street parking • 6 blocks north of Mayo Clinic • Walk-in shower • Queen bed • Full kitchen with gas stove and dishwasher • High-speed WiFI — 100+ MBPS • Shared laundry in basement

A wooden table holds a Keurig coffee maker, accompanied by a basket filled with coffee supplies. A decorative wall sign adds character above the table. Soft light filters in, illuminating a textured area rug that leads to a hallway with closed doors.

4.97 out of 5 average rating, 242 reviews

Restful sanctuary close to Mayo Clinic

This cozy space has private, self-entrance with off-street parking at no cost...a mere 2.5 miles or 10 minute drive to the Mayo Clinic downtown. Located in a quiet neighborhood in northwest Rochester. Easy access to highways, grocery store, coffee shop, Target, restaurants and biking/walking trail. Completely furnished with linens, hair-dryer, Netflix and Hulu, Smart TV and Wi-fi....and a Keurig Coffee maker with enough coffee pods to get you started. Truly, a home away from home!

4.95 out of 5 average rating, 167 reviews

A rustic wooden staircase showcases large, natural logs as steps, leading to an upper level. Light wooden railing lines the staircase, and warm wood paneling is visible on the ceiling. A houseplant can be seen at the base of the stairs, adding a touch of greenery.

Home in Stewartville

"Walden Pond" Adventure Amidst 44 Private Acres

Embark on your own "Walden Pond" adventure and be at one with nature. Each season brings its own magic: the fiery colors in fall, crunching through snow in the winter, new life in spring, and sports and activities in the summer! The 2000 s.f. log home known as 'The Bungalow" offers romantic fireplace, 2 bedrooms, 2 baths, office/bedroom + huge entertainment room. Easy drive from Rochester and all roads clear in winter. Feel safe from current coronavirus . See more info below.

The kitchen features modern bamboo cabinetry and a spacious island with a contrasting marble-like countertop. Stainless steel appliances, including a refrigerator, are integrated into the design. Natural light pours in through large windows, illuminating the space and highlighting the open layout connecting to the staircase.

4.97 out of 5 average rating, 173 reviews

Spacious Modern Home Near Mayo, St. Mary's Campus

- 5 min walk to Mayo Clinic, St. Mary’s campus - 3 bedrooms, 3 bathrooms, and a loft - unique design with vaulted ceiling and skylights in the style of Frank Lloyd Wright, one of its kind in the whole neighborhood - two-car garage + another dedicated parking space outside - walkable and safe family-friendly neighborhood close to downtown and all amenities - outside front and back patios - fusball play table - dedicated workspace - high speed wifi - Apple TVs - washer and dryer

Superhost

An outdoor deck features a glass table surrounded by four white chairs, creating a suitable dining space. Potted plants add greenery, while a grill is positioned nearby for cooking. The backyard is partially fenced, providing a sense of privacy and a view of the lush lawn.

4.83 out of 5 average rating, 247 reviews

Coastal Charm w/Jacuzzi Tub-8min to Mayo

Recently restyled/refurnished in March 2024. Coastal and a bit of boho, cozy single-family, styled to be your home away from home. 8 Min to Mayo & 7 Min to St. Mary's. Relax after a long day in a Jacuzzi tub. Equipped with various kitchen appliances and utensils (no dishwasher). Short drive to parks, groceries, Walmart, Target, etc. Smart TV & veggie garden. We're a phone call away if you have any needs. Relax, sit on the deck, or enjoy a cozy campfire.

4.97 out of 5 average rating, 225 reviews

The exterior of the Hygge House is depicted, featuring a red wooden facade and a fenced outdoor area. Comfortable seating is arranged on a patio surrounded by greenery and flower planters. Natural light filters through the large windows, enhancing the welcoming feel of the space.

Guesthouse in Rochester

Hygge House | A Cozy Guesthouse

The Hygge (pronounced hyoo·guh) House is a tiny taste of Scandinavia in Southeastern Minnesota. What is Hygge? In short, it's a Scandinavian way of living that focuses on hunkering down and creating a safe, comforting and warm place to while away. My husband and I hand built the Hygge House with your comfort in mind. We love being cozy and having space to spend together so when the opportunity arose to renovate our studio, we wanted to share it!

A laundry area is equipped with a washing machine and dryer, positioned next to a utility sink. Cleaning supplies and an iron are visibly organized nearby. A laundry basket is placed on the floor, and a neutral-colored rug covers the concrete surface.

4.98 out of 5 average rating, 341 reviews

The Guesthouse Cottage, walkable to Mayo Clinic

Our Guesthouse has a clean cottage feel. The king and queen bedrooms offer closets and quality linens. Cook meals in a fully stocked kitchen. Book an Uber, or walk 0.6 miles to Mayo's main Gonda building. We're close to grocers, coffee, parks and trails, and downtown's restaurants, shops, and a lovely public library. Free washer and dryer on site. Google TV and internet. 3-season porch. Small guest garage. No smoking on the property.

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Other great vacation rentals in Rochester

A bright and airy bedroom featuring a comfortable bed with soft linens and decorative pillows. Two windows allow for natural light, complemented by warm lamps on either side. A nightstand and an accent piece with floral artwork add character to the inviting space.

4.94 out of 5 average rating, 31 reviews

Lux 3BR Cozy Nook I Mins to Mayo & Dwtwn I Pets

MiekeRating, 5 stars2 weeks ago

Cute and cozy space that was a great home base for our family who was in the area for our daughter’s graduation. Julie was great to communicate with!

4.86 out of 5 average rating, 29 reviews

A modern kitchen features sleek gray cabinets and a granite countertop. Equipped appliances include a stainless steel refrigerator, microwave, and stove. A silver toaster and coffee maker add convenience to the space, enhanced by warm wooden beams on the ceiling that contribute to the contemporary design.

Condo in Rochester

Modern 2 Bed and 1 Bath - 6 Blocks from Mayo

CindyRating, 5 stars1 week ago

We stayed for a month and felt right at home. It was perfect for my husband and I and our grandkids were able to visit. Great location, we walked downtown almost every day. I really appreciated a months worth of garbage bags, dishtabs and other essentials. The beds are comfortable and the sofa and chair were nice.

4.93 out of 5 average rating, 60 reviews

KayBird Cottage- Entire Parkside Corner Home

BrettRating, 5 stars1 week ago

We were staying in Rochester for a wedding and lived at the Kottage for three nights. If you have up to 5 people in your party, it's a great space. Wonderful kitchen with everything you need. Beds are comfortable. Bathroom is clean and has a great shower. Very quiet and peaceful. If we ever find ourselves returning to Rochester (we're in Tennessee), we will definitely look into reserving this space again. Well worth the investment!

The exterior of a charming white cottage is shown, featuring a peaked roof and a front porch with steps leading to the entrance. Lush greenery, including small shrubs and flower beds, adds to the inviting appearance. A clear blue sky completes the scene.

4.84 out of 5 average rating, 19 reviews

Discount Charming 2 Bedroom Close to Mayo

MistyRating, 5 stars2 weeks ago

This house truly felt like a home during a very stressful time of cancer treatments. We were here for 6 weeks and the hosts were welcoming and generous and warm. We are in Rochester a couple times a year for appointments at Mayo Clinic and I can say that we won’t stay anywhere else if this rental is available. The hosts were very responsive and were able to fulfill all of our requests with speed and kindness. Great location and close to the clinic and anything else you might want to do in Rochester. It became a running joke that everything was two miles away! Thank you, Mark and John, for an amazing stay!

5 out of 5 average rating, 43 reviews

New! MN Comforts The Heart 4Bd/2Bth, 12min to Mayo

JonRating, 5 stars1 week ago

Jay’s house was in a great location, 10-15 minutes from everything in Rochester. Jay was very communicative and accommodating. House was clean and well appointed.

A walk-in shower features white subway tiles with a sloped ceiling, showcasing a built-in bench. The floor is adorned with small, decorative stones. A rain showerhead is mounted above, and a grey towel hangs on a hook nearby.

4.99 out of 5 average rating, 76 reviews

Kaleidoscope Flat 1 bd 1 mi to Mayo, Free Parking

AngelaRating, 5 stars2 days ago

We loved this little apartment! Felt like home and great place to just relax after all the appointments and testings we had to do at Mayo. Would 100% rent this place again in the future.

5 out of 5 average rating, 24 reviews

A well-maintained pathway leads between two charming cottages with modern grey exteriors and landscaped gardens. The drive is flanked by trees, providing a serene ambiance. Each cottage features a contrasting wooden entrance, ensuring a welcoming appeal. A glimpse of additional cottages is visible in the background.

Tiny home in Rochester

Luxury Cottage | 5 Blocks from Mayo | No Stairs!

Ramon DavidRating, 5 stars1 week ago

My wife and I had a wonderful one in this mini house. Since we arrived, everything was impeccably clean and very well organized. The fridge and furniture were new and modern, which provided a feeling of freshness and comfort. Each space was thought out in detail, which made us feel at home from the first moment. The house is cozy, quiet and perfect to disconnect and rest. Without a doubt, you can see the love and care they have put in every corner. We would love to go back and we totally recommend it. Thank you for giving us such a special place to enjoy as a couple!

A modern exterior of the home is showcased, featuring a blue siding with stone accents. The patio area is visible, bordered by patches of snow and landscaped grass, with a grill positioned to the side. Large windows provide views into the interior space.