Kid-friendly vacation rentals in Cape Girardeau County

Guesthouse in Cape Girardeau

A full-size bed is showcased with a light gray duvet and patterned pillows, positioned against a green headboard. Two bedside lamps are placed on either side of a small nightstand. A wall clock and storage bins add functional touches to the cozy living space.

4.92 out of 5 average rating, 111 reviews

Cozy 1-BR guest house w/free parking on premises

Enjoy a cozy experience at this centrally, located place. Literally, a 1-4 minute walk to Mercy Hospital(formerly Southeast Hospital), less than 1 mile to Southeast University Campus, along with downtown(river). A street over is Broadway with many restaurants. Walmart Market and Dollar General are also conveniently located nearby. The kitchen is fully furnished with cooking utensils, clean towels, pots and pans for those who prefer eating in. Please no animals and no smoking in the apartment.

A view from the front porch showcases a vibrant autumn scene, with trees covered in golden leaves. A cozy seating area is visible, framed by white railings, and a peaceful street with fallen leaves creates a calm atmosphere.

4.98 out of 5 average rating, 415 reviews

Beautiful Historic Boulevard District Apartment

This beautiful, private upstairs apartment is located on a favorite street in Cape Girardeau’s Historic Boulevard District. It is walking distance to SEMO University, Capaha Park, and the downtown riverfront. Recently remodeled for laundry, spacious rooms offer private bedroom spaces and a cozy den for watching movies or reading. The kitchen is fully equipped with amenities. This quiet neighborhood setting even has a front porch swing and sitting area where you can enjoy your morning coffee.

The cottage exterior presents a single-story structure with light blue siding and a dark roof. A wooden deck is located at the front, featuring a railing. The yard is grassy, bordered by a privacy fence, with a driveway visible beside the house.

4.82 out of 5 average rating, 113 reviews

Herman's Corner Cottage.

Tucked in historic Cape Girardeau, this charming cottage offers comfort and convenience. Enjoy the cozy back deck with a privacy fence—perfect for relaxing or grilling. With ample off-street parking, your stay is stress-free. The home is equipped with essentials for a smooth, hassle-free visit. Book the entire house for added privacy, providing a peaceful retreat for you and your guests. Experience the perfect blend of comfort, affordability, and convenience during your Cape Girardeau getaway.

Guest suite in Cape Girardeau

An exterior view of the entrance features a welcoming white door framed by black accents. A small staircase leads up to the door, complemented by a light fixture. A vehicle is parked near the entrance, with a tree and a fenced area visible in the background.

4.97 out of 5 average rating, 151 reviews

MAINSTAY CAPE [downtown]

Nestled in the heart of the Downtown Historic District, this suite is centrally located as a prime destination for any and all travelers alike. With parking available, this space offers a unique & trendy “midwest boho” vibe. ~WALKABLE~ Our studio is 1 block from the bustling Southeast Missouri State University, 1 block from the gorgeous Capaha Park, and 2 blocks from Mercy Hospital. If you are interested in night life, this space is simply a 5-10 minute walk to all DT bars and restaurants.

A spacious living area features large windows allowing natural light to fill the space. A comfortable grey sofa is paired with a unique coffee table, while stylish dining chairs surround a white table. The kitchen area includes modern appliances and cabinetry.

4.95 out of 5 average rating, 245 reviews

Brand new 2 bedroom unit right in downtown Cape.

This special place is close to everything, making it easy to plan your visit. Walking distance to restaurants, the river and nightlife. Property includes wifi, full kitchen, laundry, deck and private parking for one. One king bed room and a twin bed room in addition to a roll out twin bed along with a 60 inch smart television. Dog bed and bowls included along with board games! Property is conveniently located across the street from "The Bar" the famous spot from the movie "Gone Girl" .

A spacious dining area is seen with a glass table surrounded by light blue chairs. A stylish chandelier hangs overhead, illuminating the space. Decor includes a large area rug and decorative elements, while bicycles are parked nearby, hinting at an outdoor adventure option.

4.86 out of 5 average rating, 609 reviews

Unique Design | Walk Downtown/River | .5 mile SEMO

At our Adventurous 2 Bedroom Suite you’ll first arrive at a Brightly decorated Space with Artsy Walls and Bold Decor. Designed with its History in mind & a twist of Creativity, you will Immerse Yourself within your Stay; from our Stocked Kitchen, Reading Area with Indoor Swing to Themed & Cozy Bedrooms. Enjoy being near Downtown/the River with a short Bike Ride or Walk and when you are ready to Tuck in at night, Sink into our 10” Memory Foam mattress with Plush Pillows and feel at Ease.

Treehouse in Cape Girardeau

The custom-built treehouse is elevated on stilts, surrounded by greenery. A spacious deck features a railing, offering access to the entrance. Steps lead to the ground below, while large glass doors enhance the connection to nature.

4.99 out of 5 average rating, 141 reviews

Twisted Sassafras Treehouse

A custom-built treehouse located on 10 acres with a water view that you can take in from the hot tub on the deck! It is nestled high in the trees and is the perfect romantic getaway for two! Feel like you are away from it all without being away from it all! This treehouse is located on a county road just minutes from Cape Girardeau. Enjoy catch and release fishing on site, local wineries, shopping in historic downtown Cape Girardeau, local restaurants, gambling, historical sites & more!

A spacious living room is furnished with a large sectional couch, complemented by decorative pillows. A wooden coffee table sits center stage on an area rug. A ceiling fan is visible, and light enters through window treatments, creating a comfortable atmosphere.

4.85 out of 5 average rating, 124 reviews

5 Bed Home in Great Neighborhood - Sleeps 10

Looking for a comfortable and spacious Airbnb in Cape Girardeau? 🏡✨ This 3 bedroom, 2 bathroom home in a great neighborhood is the perfect spot for your next group stay. This home features great living areas to relax and unwind including a living room with a large sectional and 70 inch TV. The game room features an air hockey table, dart board, and other board games. It will sleep 10 comfortably. Make this your destination for your next girls trip, sports tournament, or SEMO event.

A comfortable living room is presented with soft, beige seating adorned with red accent pillows. A dark trunk serves as a coffee table, while a lamp gently illuminates the space. The room features multiple windows, enhancing natural light alongside decorative curtains.

4.87 out of 5 average rating, 103 reviews

House Of Clubs- 2 Bed 1.5 Bath

The PERFECT hideway. The House of Clubs offers a quiet setting with a creek that wraps around the enitre property. Two bedrooms, each include a queen size bed. One Full bathroom. Full Laundry room that also offers a private cammode. The stylish living room offers a unique style that higlights Cape Girardeaus rich history. Enjoy your morning coffee in the four seasons room with breathtaking views of this hidden gem . Less than 5 minutes to downtown. Only 2 minutes to Cape Country Club.

4.96 out of 5 average rating, 195 reviews

A modern farmhouse is depicted at sunset, featuring a welcoming entrance with a covered porch. A stone pathway leads to the front door, bordered by a grassy lawn that extends to fields and trees in the background.

Barn in Cape Girardeau

Under the Stars - Farmhouse

Enjoy the tranquility of this modern farmhouse charmer! Custom built minutes from downtown Cape. Relax outside around the fire pit, roast marshmallows and watch the sunset. Finish the night with a long soak in the hot tub. Start the morning on the front porch rocking chairs and take in a sunrise. Open concept, fully equipped kitchen, 3 Bd. including King master/full bath, 2 Queens with full guest bath. Near Trail of Tears and walking distance to classic dive bar/burger joint

Guesthouse in Cape Girardeau

The exterior of the guesthouse features a charming brick facade with yellow shutters framing the windows. A sturdy front door painted in a vibrant hue complements the traditional architecture. Flower boxes add a touch of color, while a manicured garden enhances the welcoming appearance.

4.94 out of 5 average rating, 515 reviews

Downtown Guesthouse- Romantic Getaway

The guesthouse seamlessly blends modern amenities with historic charm in a cozy, compact space. The antique claw foot tub/shower combo offers a charming, yet snug, spot for a relaxing soak—true to its historic roots, the bathroom could be best described as a quaint water closet. After a day of exploring unwind in the patio. Play a favorite record, and savor your coffee while daydreaming about new experiences. Despite its small size, it provides all the modern comforts you need.

A brightly lit bedroom features two beds with decorative headboards and comfortable bedding. Pillows are arranged neatly on each bed, complemented by window treatments that allow natural light to filter in. The hardwood floor adds a warm touch to the inviting space.

4.77 out of 5 average rating, 100 reviews

Historic Blvd District Home in Cape Girardeau

This beautiful, private home is located on a favorite street in Cape Girardeau’s Historic Boulevard District. It is walking distance to SEMO University, Capaha Park, and the downtown riverfront. With large bedrooms, spacious living room and separate dining room you will have all the room you need! The kitchen is fully equipped with amenities. This quiet neighborhood setting with a big front porch sitting area where you can enjoy your morning coffee.

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Popular amenities for Cape Girardeau County kid-friendly rentals

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Kid-friendly house rentals

The exterior of a charming one-story house is displayed, featuring a sloped roof with a pointed peak. Two planters with colorful flowers flank the steps leading to the entrance, surrounded by lush greenery and autumn foliage.

5 out of 5 average rating, 11 reviews

Urban Cape Downtown Escape-The Rivertown Nook

Don & SylviaRating, 5 stars2 days ago

Staci's home is a lovely home in a perfect location in downtown Cape. The home clean, classy and cozy. The beds are very comfy, the bathroom is great, and the kitchen has everything you need. On top of all that, Staci is a super responsive host. We thoroughly enjoyed our stay there and can't wait to return. Highly recommended.

A relaxed living area is furnished with a spacious sectional couch in varying shades of green. A wooden coffee table sits at the center, accompanied by a decorative cabinet displaying items. A projector screen displays a flickering fire image, with curtains framing the windows.

4.89 out of 5 average rating, 18 reviews

SEMO Redhawks Campus Home with Hot Tub

KathleenRating, 5 stars1 month ago

Carisa's home felt very safe, very humble and just so thought out. My puppy felt at home too with his times to go outside for his needs. People talk about their home away from home when this is most totally home away from home! Thanks Carisa!!

The exterior of the home features a single-story structure with a neutral-colored façade and a welcoming front porch. A large window provides ample natural light, while neatly trimmed shrubs and greenery frame the entrance. A curved walkway leads to the front door.

4.86 out of 5 average rating, 7 reviews

Cape Charm: 3 BR Close to SEMO & Mercy! CLEAN!

RogerRating, 5 stars1 month ago

Great place to stay while visiting out son at SEMO. Can't wait to come back during football season. 5 star all the way.

The exterior of a charming brick house is presented, surrounded by manicured green grass and shrubs. Large windows invite natural light, while the roof features a small chimney. A clear blue sky and scattered clouds create a pleasant backdrop to the home.

4.96 out of 5 average rating, 24 reviews

Located near downtown and casino

HeatherRating, 5 stars3 weeks ago

Great house, great location. Quiet neighborhood. Beds were comfortable. Plenty of room for my son to play. He loved playing in the basement.

A charming brick home features a welcoming front porch adorned with colorful flower pots and a variety of plants. A stone pathway leads to the entrance, and vibrant seating is arranged on the porch, providing an inviting outdoor space.

4.88 out of 5 average rating, 74 reviews

Downtown Home steps away from Food and Fun

TerasaRating, 5 stars3 weeks ago

downtown location with restaurants in walking distance, clean home, everything was well labeled and easily accessed. There's a quick response time to questions about the area and home. we enjoyed the stay and would return.

A charming two-story cottage features a red exterior with stone accents. The covered front porch is furnished with several chairs, providing a welcoming space. Large windows allow natural light to fill the interior, while a path leads to the entrance, framed by well-kept grass and plants.

4.95 out of 5 average rating, 22 reviews

Walnut Haven (formerly Rose Hill Cottage)

StephanieRating, 5 stars1 month ago

Carla was wonderful and the home was fantastic!! She was incredibly helpful in letting me know how far her home was from the events we were attending. The house was wonderfully clean and it was a great area.

A vibrant living area features a mix of colorful seating options, including a pink armchair and a blue sofa. A stylish area rug with abstract patterns adds visual interest. A dining space can be seen in the background, inviting gatherings and shared moments.

4.96 out of 5 average rating, 46 reviews

Boho Chic

KaylaRating, 5 stars1 month ago

Chantel's listing was just as described. She was very responsive. Has was super cute and cozy!

A charming brick home features a welcoming front porch supported by white columns. A neatly paved walkway leads to the entrance, surrounded by green grass and landscaped greenery. Large windows allow natural light to illuminate the interior spaces.

5 out of 5 average rating, 8 reviews

Relax Here! off Broadway

KrystaRating, 5 stars7 months ago

Derek was very helpful last minute when we needed somewhere to stay. I am grateful for his help. He was always fast to respond and the home was as described.

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Kid-friendly apartment rentals

A private deck is highlighted, featuring a round glass table surrounded by six black metal chairs. The scenic view includes the Mississippi River and a colorful sunset, with the silhouette of the Emerson bridge visible in the background.

4.95 out of 5 average rating, 42 reviews

Downtown Condo on the River

GrahamRating, 5 stars3 months ago

Michael's place in Cape G is a perfect place to stay while you visit. It's a block from the main drag with plenty of food and bars (check out the record lounge around the corner). There's a garage space, and the balcony on the top floor has views of the Mississippi. The apartment is clean and comfortable, it would be a good medium or long term stay if desired. The bed is comfortable, and the kitchen and bathroom are modern. We'd stay again if visiting.

Apartment in Old Appleton

A red steel bridge spans over a serene creek, with water cascading down a rocky ledge in the foreground. Lush greenery surrounds the area, enhancing the peaceful ambiance of the scene. The sky is partly cloudy, adding to the tranquil atmosphere.

5 out of 5 average rating, 32 reviews

Apple Creek Loft

JeremyRating, 5 stars3 weeks ago

This place was way more than enough space for three of us, in fact at the price point it’s a great deal for the size. There is a beautiful waterfall right by the entryway, I kept my bedroom window open all night so I could hear it. Everything was really clean and we were able to use the kitchen to cook breakfast. I would definitely stay here again. They have some older TVs that are CRT based, so if you have an old NES with Duck Hunt bring it!!! Duck Hunt won’t work on new HDTVs. We were on motorcycles so we parked out front. The back parking lot is gravel and there’s a little bit of a rough entryway if you’re on bikes. Laundry room is big and works great. I wish we had more time to spend around the area. It was nice and quiet and very clean.

An open living area features warm wood flooring and exposed beams. A comfortable couch and a small rug are positioned near a modern kitchen island, which is surrounded by black cabinetry. Natural light fills the space through large windows, enhancing the urban loft ambiance.

4.86 out of 5 average rating, 22 reviews

Downtown Loft 1 on Main

GinaRating, 5 stars3 months ago

We loved our stay! It’s in a perfect location If you want to hang out downtown! We walked to hot shots to meet friends and it was very enjoyable!

A spacious living area features dark hardwood floors and light gray walls, accented by a comfortable leather sofa and an elegant coffee table. Artwork adorns the walls, and natural light streams in from the nearby windows, illuminating the inviting space.

4.93 out of 5 average rating, 41 reviews

Downtown 4BR with 2 King Beds! Off-street parking

MarcusRating, 5 stars1 month ago

Beautiful place. Great location. Plenty of amenities. I would stay there anytime I'm in town.

4.95 out of 5 average rating, 43 reviews

A serene view of the Mississippi River is presented, highlighting the tranquil water and the pavilion that juts into the river. Lush green grass borders the water, and trees line the distant shore, creating a natural landscape under a clear sky.

Apartment in Scott City

RiverSide Barn Suite on the Mississippi River.

LaraRating, 5 stars2 months ago

Great place to stay and within walking distance to great restaurant. Deb was amazing to work with and very responsive. Beds were comfortable and we had a great time. We will definitely stay here again.

The living room features comfortable seating for four and a bay window providing natural light. A SmartTV is mounted on the wall, with a cozy fireplace ambiance displayed. Decorative plants and framed artwork enhance the welcoming environment, inviting relaxation.

5 out of 5 average rating, 3 reviews

Rivers Dawn- Historic Home - River View - King Bed

LindaRating, 5 stars3 months ago

Accommodations are comfortable, extremely clean and equipped with everything one needs for a weekend or extended stay. Would definitely stay again.

A wooden bed with a dark blue bedding set is centered in the room, complemented by an ornate headboard. Two upholstered chairs provide seating, while soft lighting from two lamps enhances the intimate setting. A glimpse of the kitchen is visible through the doorway.

4.91 out of 5 average rating, 11 reviews

Colorful Home in Cape

ChadleyRating, 5 stars3 weeks ago

Stayed in the wood room. Clean, very spacious, comfortable, etc. Would stay again. Rodney was available and proactive with communication. Located very close to downtown.