
House vacation rentals in Santo Domingo
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Top-rated house rentals in Santo Domingo
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El Refugio: Nature Escape in Chitre
El Refugio at Playa El Agallito, Chitré: Nature Escape: Just 7 minutes from downtown Chitré, El Refugio is a fully equipped countryside home, perfect for disconnecting in a natural setting. Surrounded by mangroves and accommodating up to 8 guests, it offers a unique experience for couples, families or digital nomads. Enjoy bird watching, the peaceful surroundings, and the comfort of our large gazebo. Ideal for those seeking simple relaxation and a close connection to nature. A unique experience

Nearly Oceanfront: Blue 3 Bedroom Spacious Villa
Villa-33, your exquisite retreat nestled within Blue Playa Venao. Discover a tropical paradise of stunning beaches. Embark on endless adventures just a short walk away. This beautiful Villa offers 3 bedrooms and 3 baths. Two of the bedrooms feature queen beds, while the third bedroom has 2 twin beds, ensuring a restful night's sleep for everyone. The living area, kitchen, and terrace are thoughtfully equipped with everything you need to make yourself at home during your fun family getaway.

3 min to Pedasi, 5 min to the Beach, Private Pool!
Your family will be close to everything when you stay at this centrally-located place. Outfitted with room to sleep 6 and a fenced yard for your dog, Casa Catch and Relax has it all! Look us up online, Casa Catch and Relax You'll Love - Beach access a short drive or walk away (3 min drive, 10 min walk) - Central to town and local restaurants - Private, fenced outdoor space with pool - Cool days and nights with A/C in every room - Fully equipped kitchen and tons of sleeping space - Wifi

A Good Walk-Pedasi
Choose Una Buena Caminata-Nestled on stunning Azuero Peninsula, minutes from charming, laid-back Pedasí. This serene coastal retreat offers tranquility, nature & adventure, surrounded by greenery and the sounds of the Pacific. Walk Playa Arenal, where humpback whales breach offshore during migration season. Hit world-class surf breaks: Playa Venao and Playa El Toro. Enjoy sport-fishing w deep-sea charters. Soak in the unique rhythms of life near Pedasí—where time slows and paradise begins.

Country House Like in the City / La Casita
Casa fresca, con árboles y naturaleza. Áreas amplias para descansar. Ubicación céntrica, cerca de malls, restaurantes, estación de buses y ciclovía. Entrada privada, estacionamientos, cocina completa, mobiliario completo, baño, TV HD con cable, AC en recámara, agua caliente y Wi-Fi. ENG, PORT, FRAN and ITA Spoken! Ahora, Chitré, tiene un problema con el agua: no está potable; tenemos 50% de lo habitual, a veces estamos sin agua por algunas horas. Por favor, consulten antes de reserar.

Pedasí, Los Destiladeros Beach / Casa Serena
❤ Welcome to Casa Serena, escape to our stunning 3-bedroom ocean view house, perfectly located in Playa Los Destiladeros, an area of beautiful beaches in Pedasí. This unique retreat offers a blend of modern luxury and coastal charm, ensuring an unforgettable vacation experience for you and your loved ones. Book your stay today and experience the magic of Casa Serena. Create lasting memories with your family and friends in this perfect ocean view escape.

Casa Samambaia - sea view tropical paradise w pool
With a modern tropical design, this home features a cozy living room and a stylish kitchen at the center of the social area. Open the glass doors to immerse yourself in open-concept living, seamlessly blending the indoors with the main terrace and the pool, all oriented towards the ocean view. With two en-suite bedrooms with AC and fans, the house is immersed in nature, green mountains, and a lovely garden, everything 5 minutes from the beach center.

Casa Pelicano - Tropical house w pool and seaview
Welcome to Casa Pelicano! Indulge yourself in a retreat with breathtaking views of the ocean and mountains from every corner. Unwind in the private refreshing pool, where the turquoise waters seem to blend seamlessly with the horizon. The stylish interior features open-plan living spaces, perfect for entertaining or relaxing. Whether you're soaking up the sun or gazing at the moonlit ocean under the stars, this home is your ultimate escape.

A minimalist Casita in Pedasi
Imagine a peaceful casita with ocean views and a nearby pool house boasting an edgeless pool overlooking the ocean. Plus, you have your own private beach. Inside, you will find an open-concept living space adorned with simple yet stylish furnishings, designed for relaxation and comfort. It's the perfect blend of tranquility, peaceful seclusion and breathtaking natural beauty. Gated community, 24 hour security

Casa Inito - Romantic Getaway
Indulge in the charm of Casa Inito, a thoughtfully crafted haven that invites you to experience a one-bedroom retreat like no other. This well-designed space seamlessly blends modern comfort with an intimate setting, creating the perfect atmosphere for your getaway. The Villa is located just 7 minutes from Playa Venao Beach (by car). ****(Vehicle a MUST, preferably SUV due to steep paved access road)****

Apartment in Chitré
Your family will be close to everything if you stay at this accommodation. With easy access to public or private transportation. It has 2 double beds, mini bar refrigerator, air conditioner, 3-burner gas stove, separate bathroom and parking for your vehicle. Just a few minutes from downtown Chitré. You will have parks, restaurants and endless places to visit nearby.

Spacious house in Villa de los Santos
Comfortable family accommodation in La Villa de Los Santos, with Wi-Fi, A/C, equipped kitchen, patio and parking. Located near supermarkets and plazas. Just 15 minutes from El Rompió y Monagre, 45 minutes from Isla Iguana and 1h 30 minutes from Playa Venao.
Popular amenities for Santo Domingo house rentals
House rentals with a pool

Tropical Townhouse Living

Casa Del Amor - Main Floor - on the beach.

NinaHouse, spacious and cool house in Chitré.

Casa Magna - Casa Completa

Pedasí: Andromeda Boroda 4-6 p. Beach, swimming pool

Elegant Friends & Family Escape |Oceanfront Pool

Hillside Oceanview Home with Pool in Venao

Casa Carolina: Spacious 3 Bedroom at Blue Venao
Weekly house rentals

Chitré, family home

Great for Festivities

La Hacienda Ojo de Agua * Family & Friends Getaway

Pedasí, Earth House Casa Alegre / 3BR

Beautiful House for Rent in Downtown Chitré

La Casita 4BR Spacious Private Paradise w/pool

Chitré: Weliss' House

Cozy house in El Ejido
Private house rentals

Modern Beach Home with pool and hot tub

Ocean View, Ocean View El Ciruelo

Casa Luna 2 bdrm 2 bath walk to square!

Peaceful Pedasi

House in Pedasí, near beaches

Charming Pedasi Retreat

Beautiful home near the beaches in Pedasi, Panama.

Villa Cristina
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