House vacation rentals in Los Santos Province

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Top-rated house rentals in Los Santos Province

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite

A charming beach house is surrounded by lush greenery and palm trees, elevated on sturdy pillars. The thatched roof complements the tropical setting, while large windows provide ample natural light. A spacious wooden deck with railing enhances the inviting outdoor space.

Home in Cambutal

4.89 out of 5 average rating, 18 reviews

Seaside Sanctuary • Steps to Surf • Fast Internet

Wake up to the rhythmic sounds of waves steps from your bed in this intimate beachfront paradise. Our charming one-bedroom home sits directly on Cambutal's pristine shoreline, offering ocean views and instant beach access. Relax on your private terrace with morning coffee as the sun rises, cook meals in the fully-equipped kitchen, and fall asleep to the soothing sounds of the surf. With Starlink internet, you can stay connected while experiencing the perfect blend of seclusion and convenience.

Guest favorite

A private pool is framed by a stone patio, surrounded by lush greenery and tropical plants. A shaded area features outdoor seating and a grill, while the enclosed space provides a sense of tranquility. The home is visible in the background, set against a clear blue sky.

Home in Pedasí

4.93 out of 5 average rating, 176 reviews

3 min to Pedasi, 5 min to the Beach, Private Pool!

Your family will be close to everything when you stay at this centrally-located place. Outfitted with room to sleep 6 and a fenced yard for your dog, Casa Catch and Relax has it all! Look us up online, Casa Catch and Relax You'll Love - Beach access a short drive or walk away (3 min drive, 10 min walk) - Central to town and local restaurants - Private, fenced outdoor space with pool - Cool days and nights with A/C in every room - Fully equipped kitchen and tons of sleeping space - Wifi

Guest favorite

A single-story house is nestled beneath a large tree, featuring a tiled roof and a covered parking area. Surrounding greenery includes bushes and ornamental plants, enhancing the natural setting. The house is positioned to provide a sense of privacy and tranquility.

Home in Chitré

4.87 out of 5 average rating, 62 reviews

Country House Like in the City / La Casita

Casa fresca, con árboles y naturaleza. Áreas amplias para descansar. Ubicación céntrica, cerca de malls, restaurantes, estación de buses y ciclovía. Entrada privada, estacionamientos, cocina completa, mobiliario completo, baño, TV HD con cable, AC en recámara, agua caliente y Wi-Fi. ENG, PORT, FRAN and ITA Spoken! Ahora, Chitré, tiene un problema con el agua: no está potable; tenemos 50% de lo habitual, a veces estamos sin agua por algunas horas. Por favor, consulten antes de reserar.

Superhost

The house exterior features a warm peach-colored facade with a large white-framed window. Tropical palm trees and vibrant flowering shrubs border the front, providing a refreshing touch to the entrance.

Home in Chitré

4.83 out of 5 average rating, 72 reviews

NINA HOUSE, a spacious and cool house in Chitré.

House just for you, up to 7 p, spacious and in one of the best areas of Chitré, quiet and family, access to the pool in the social area, parks and courts, close to everything: supermarkets, casino, bus; come to Chitre and enjoy typical meals, crafts; plan your walks and stop at Nina House and visit the best beaches: Pedasi, Venao, Isla Iguana, you can work from NinaHouse with a fast internet. We now have air conditioning in the living room for your comfort.

Guest favorite

The exterior of Casa Serena showcases a spacious two-story structure with a warm, inviting facade featuring wooden accents. A wooden deck surrounds a private pool, and comfortable lounge chairs are positioned beside it. Umbrellas provide shade, while lush greenery complements the peaceful setting.

Home in Playa Los Destiladeros

5 out of 5 average rating, 11 reviews

Pedasí, Los Destiladeros Beach / Casa Serena

❤ Welcome to Casa Serena, escape to our stunning 3-bedroom ocean view house, perfectly located in Playa Los Destiladeros, an area of beautiful beaches in Pedasí. This unique retreat offers a blend of modern luxury and coastal charm, ensuring an unforgettable vacation experience for you and your loved ones. Book your stay today and experience the magic of Casa Serena. Create lasting memories with your family and friends in this perfect ocean view escape.

Guest favorite

The exterior showcases a modern structure with wooden paneling and large glass doors. A shower is visible alongside a lush garden featuring tropical plants and vibrant flowers. Stone path leads to the entrance, framed by greenery and gentle sunlight.

Home in Playa Venao

4.96 out of 5 average rating, 57 reviews

Casa Samambaia - sea view tropical paradise w pool

With a modern tropical design, this home features a cozy living room and a stylish kitchen at the center of the social area. Open the glass doors to immerse yourself in open-concept living, seamlessly blending the indoors with the main terrace and the pool, all oriented towards the ocean view. With two en-suite bedrooms with AC and fans, the house is immersed in nature, green mountains, and a lovely garden, everything 5 minutes from the beach center.

Guest favorite

Home in Playa Venao

4.92 out of 5 average rating, 50 reviews

Casa Pelicano - Tropical house w pool and seaview

Welcome to Casa Pelicano! Indulge yourself in a retreat with breathtaking views of the ocean and mountains from every corner. Unwind in the private refreshing pool, where the turquoise waters seem to blend seamlessly with the horizon. The stylish interior features open-plan living spaces, perfect for entertaining or relaxing. Whether you're soaking up the sun or gazing at the moonlit ocean under the stars, this home is your ultimate escape.

Guest favorite

The outdoor area features a spacious infinity pool surrounded by a sun deck, complete with lounge chairs. Lush greenery and palm trees can be seen in the background, under a bright blue sky with fluffy clouds, creating a serene outdoor retreat.

Home in Pedasí

4.95 out of 5 average rating, 19 reviews

Villa La Jungla featuring a New Pool

Escape to this serene, private retreat just minutes from Pedasí, Playa Venao, and stunning beaches. Perfect for 4–8 guests, the home features spacious en-suite bedrooms with quality linens, a fully equipped kitchen, and a newly resurfaced infinity pool. Enjoy total privacy, comfort, and easy access to local adventures. Whether you're here to surf, explore, or relax, this is your ideal home base for a peaceful and memorable stay.

Superhost

A scenic view captures the villa nestled among lush greenery, with a winding path leading to the entrance. The surrounding landscape features dense trees, enhancing the sense of seclusion and tranquility within nature.

Home in Provincia de Los Santos

5 out of 5 average rating, 5 reviews

Casa Inito - Romantic Getaway

Indulge in the charm of Casa Inito, a thoughtfully crafted haven that invites you to experience a one-bedroom retreat like no other. This well-designed space seamlessly blends modern comfort with an intimate setting, creating the perfect atmosphere for your getaway. The Villa is located just 7 minutes from Playa Venao Beach (by car). ****(Vehicle a MUST, preferably SUV due to steep paved access road)****

Top guest favorite

The two-story house is framed by lush greenery, featuring large glass doors that open to a spacious patio. Comfortable seating areas are provided, accompanied by tropical plants. Warm outdoor lighting hangs above, enhancing the inviting ambiance, while views of the sea are visible through the glass.

Home in Cambutal

5 out of 5 average rating, 20 reviews

Beach side stay at Casa Blanca

This beautiful two bedroom, double-storey house sits in one of the best locations around, nestled amongst the trees and overlooking a stunning swimming bay in the tropical paradise of Cambutal. Perfectly situated, you will have the warm Pacific Ocean literally on your doorstep, as well as easy access to the highlights of a beach holiday - surfing, swimming, sunsets and more.

Guest favorite

Home in Chitré

4.73 out of 5 average rating, 15 reviews

Chitré, family home

Relax in our central and spacious home in Chitré, steps away from Hospitals, Church, School, Restaurants, Cyclovia and many more amenities. In our residence we have a king bed in the master bedroom with TV and a double bed in the second bedroom, both with air conditioning. She can use all kitchenware as needed. We would be happy to host you in our cozy residence.

Guest favorite

Home in La Villa de Los Santos

4.94 out of 5 average rating, 97 reviews

Spacious house in Villa de los Santos

Comfortable family accommodation in La Villa de Los Santos, with Wi-Fi, A/C, equipped kitchen, patio and parking. Located near supermarkets and plazas. Just 15 minutes from El Rompió y Monagre, 45 minutes from Isla Iguana and 1h 30 minutes from Playa Venao.