
House vacation rentals in Los Santos Province
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Top-rated house rentals in Los Santos Province
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Breathtaking Views: Sleeps 13, Walk to Beach!
There’s something special about this place. Every guest says the same thing—they never want to leave. Imagine waking up to the sound of waves and birdsong, sipping coffee on the balcony with sweeping ocean views. This peaceful retreat in Venao is at the quiet end of the beach, away from the party scene—but close enough to dive into the action when you want. Swim, surf, and dine nearby, then come home to the tranquility of your private lodge, where the only nightlife is the glow of the stars.

Nearly Oceanfront: Blue 3 Bedroom Spacious Villa
Villa-33, your exquisite retreat nestled within Blue Playa Venao. Discover a tropical paradise of stunning beaches. Embark on endless adventures just a short walk away. This beautiful Villa offers 3 bedrooms and 3 baths. Two of the bedrooms feature queen beds, while the third bedroom has 2 twin beds, ensuring a restful night's sleep for everyone. The living area, kitchen, and terrace are thoughtfully equipped with everything you need to make yourself at home during your fun family getaway.

3 min to Pedasi, 5 min to the Beach, Private Pool!
Your family will be close to everything when you stay at this centrally-located place. Outfitted with room to sleep 6 and a fenced yard for your dog, Casa Catch and Relax has it all! Look us up online, Casa Catch and Relax You'll Love - Beach access a short drive or walk away (3 min drive, 10 min walk) - Central to town and local restaurants - Private, fenced outdoor space with pool - Cool days and nights with A/C in every room - Fully equipped kitchen and tons of sleeping space - Wifi

Beachfront Gem w/ Ocean Views & Prime Surf Access
Welcome to your slice of beachfront paradise! Our home sits right on Cambutal's beautiful shoreline. Gorgeous ocean views greet you from every window, while the gentle rhythm of waves creates the perfect soundtrack for your stay. We've equipped the house with Starlink WiFi and a large dining table that doubles as an ideal workspace, making this a perfect retreat for both vacationers and remote workers. The house feels like a real home – comfortable, clean, and ready for your beach memories.

A Good Walk-Pedasi
Choose Una Buena Caminata-Nestled on stunning Azuero Peninsula, minutes from charming, laid-back Pedasí. This serene coastal retreat offers tranquility, nature & adventure, surrounded by greenery and the sounds of the Pacific. Walk Playa Arenal, where humpback whales breach offshore during migration season. Hit world-class surf breaks: Playa Venao and Playa El Toro. Enjoy sport-fishing w deep-sea charters. Soak in the unique rhythms of life near Pedasí—where time slows and paradise begins.

Country House Like in the City / La Casita
Casa fresca, con árboles y naturaleza. Áreas amplias para descansar. Ubicación céntrica, cerca de malls, restaurantes, estación de buses y ciclovía. Entrada privada, estacionamientos, cocina completa, mobiliario completo, baño, TV HD con cable, AC en recámara, agua caliente y Wi-Fi. ENG, PORT, FRAN and ITA Spoken! Ahora, Chitré, tiene un problema con el agua: no está potable; tenemos 50% de lo habitual, a veces estamos sin agua por algunas horas. Por favor, consulten antes de reserar.

Pedasí, Los Destiladeros Beach / Casa Serena
❤ Welcome to Casa Serena, escape to our stunning 3-bedroom ocean view house, perfectly located in Playa Los Destiladeros, an area of beautiful beaches in Pedasí. This unique retreat offers a blend of modern luxury and coastal charm, ensuring an unforgettable vacation experience for you and your loved ones. Book your stay today and experience the magic of Casa Serena. Create lasting memories with your family and friends in this perfect ocean view escape.

Casa Samambaia - sea view tropical paradise w pool
With a modern tropical design, this home features a cozy living room and a stylish kitchen at the center of the social area. Open the glass doors to immerse yourself in open-concept living, seamlessly blending the indoors with the main terrace and the pool, all oriented towards the ocean view. With two en-suite bedrooms with AC and fans, the house is immersed in nature, green mountains, and a lovely garden, everything 5 minutes from the beach center.

Casa Pelicano - Tropical house w pool and seaview
Welcome to Casa Pelicano! Indulge yourself in a retreat with breathtaking views of the ocean and mountains from every corner. Unwind in the private refreshing pool, where the turquoise waters seem to blend seamlessly with the horizon. The stylish interior features open-plan living spaces, perfect for entertaining or relaxing. Whether you're soaking up the sun or gazing at the moonlit ocean under the stars, this home is your ultimate escape.

Villa La Jungla featuring a New Pool
Escape to this serene, private retreat just minutes from Pedasí, Playa Venao, and stunning beaches. Perfect for 4–8 guests, the home features spacious en-suite bedrooms with quality linens, a fully equipped kitchen, and a newly resurfaced infinity pool. Enjoy total privacy, comfort, and easy access to local adventures. Whether you're here to surf, explore, or relax, this is your ideal home base for a peaceful and memorable stay.

Casa Inito - Romantic Getaway
Indulge in the charm of Casa Inito, a thoughtfully crafted haven that invites you to experience a one-bedroom retreat like no other. This well-designed space seamlessly blends modern comfort with an intimate setting, creating the perfect atmosphere for your getaway. The Villa is located just 7 minutes from Playa Venao Beach (by car). ****(Vehicle a MUST, preferably SUV due to steep paved access road)****

Beach side stay at Casa Blanca
This beautiful two bedroom, double-storey house sits in one of the best locations around, nestled amongst the trees and overlooking a stunning swimming bay in the tropical paradise of Cambutal. Perfectly situated, you will have the warm Pacific Ocean literally on your doorstep, as well as easy access to the highlights of a beach holiday - surfing, swimming, sunsets and more.
Popular amenities for Los Santos Province house rentals
House rentals with a pool

Tropical Townhouse Living

2/2 Private Oasis Pedasi's best location & rental!

La Hacienda Ojo de Agua * Family & Friends Getaway

Casa Del Amor - Main Floor - on the beach.

A minimalist Casita in Pedasi

NinaHouse, spacious and cool house in Chitré.

Casa Magna - Casa Completa

Elegant Friends & Family Escape |Oceanfront Pool
Weekly house rentals

Ocean View, Ocean View El Ciruelo

Great for Festivities

Pedasí, Earth House Casa Alegre / 3BR

House in the center of Las Tablas

La Casita 4BR Spacious Private Paradise w/pool

Cozy country-style house.

Casa Iguana 3 -Sleep 4-queen bed & 1 bunk bed

Chitré: Weliss' House
Private house rentals

Casa Amarilla-Cozy 2Bed/1Bath/Pocri, Las Tablas

Casa Las Tablas

Las Tablas Comfy and Spacious Private Room

Peaceful Pedasi

Casa Concha at Luna Negra

Casa Gerard

Cozy house in El Ejido

Beautiful home near the beaches in Pedasi, Panama.
Destinations to explore
- Waterfront rentals Los Santos Province
- Villa rentals Los Santos Province
- Pet-friendly rentals Los Santos Province
- Rentals with an accessible height bed Los Santos Province
- Family-friendly rentals Los Santos Province
- Rentals with a patio Los Santos Province
- Apartment rentals Los Santos Province
- Beachfront rentals Los Santos Province
- Smoking-friendly rentals Los Santos Province
- Rentals with a washer and dryer Los Santos Province
- Rentals with a fire pit Los Santos Province
- Rentals with outdoor seating Los Santos Province
- Boutique hotels Los Santos Province
- Rentals with beach access Los Santos Province
- Rentals with pools Los Santos Province
- Rentals with a hot tub Los Santos Province
- Guesthouse rentals Los Santos Province
- Condo rentals Los Santos Province
- Hotel rooms Los Santos Province
- Bed and breakfasts Los Santos Province
- House rentals Panama




