Family-friendly vacation rentals in Rochester

A cozy living area is featured, highlighting a brick fireplace with a warm glow. A marble countertop is positioned in the foreground, accompanied by two glasses of red wine and a plate of assorted fruit garnished with a purple flower. Natural light accentuates the scene.

4.93 out of 5 average rating, 192 reviews

The BEST Stay in Town: See Pics+Reviews to Believe

One level living/no stair. 2 bedrooms with 3 beds One-side of a duplex home: 1,200 Squarefeet w/ your own private entry, parking, laundry, kitchen.. 2.5 miles to Mayo, Target, Hyvee, gas stations...Fully furnished home. Smart TV & Fridge w/ Superfast internet & NetFlix included. Easy self-check-in keypad. A few blocks to the bus stop. Modern/spacious interior. Fully equipped kitchen w/ dishwasher, pots, pans, and washer/dryer at no additional cost. Fireplace & private deck. 3 parking spaces

A garden-level apartment is accessed via a gravel driveway that leads to a charming home. Lush greenery surrounds the path, and the structure features a mix of siding colors, with large windows framed by blue shutters, creating an inviting exterior appearance.

4.94 out of 5 average rating, 218 reviews

Woodland Retreat, Full private walkout lower level

Peaceful retreat down gravel driveway 15 min from Mayo Clinic. Enjoy your own apartment with private backyard walkout entrance to the lower level of our home. You will have a bedroom, living area, kitchenette with mini fridge, microwave and toaster oven (no conventional stove/oven), bathroom w/ tub & shower, pingpong table, laundry, and patio with fire ring. You may hear piano music weekday afternoons, since I give lessons (usually 3-6 pm; a bit earlier in summer) NEW HEATED FLOORS w/thermostat

The living room includes a dark leather sectional sofa and a striped armchair, both positioned around a round coffee table. A vibrant piece of artwork adorns the wall, while natural light enters through two windows, complemented by soft curtains.

4.86 out of 5 average rating, 252 reviews

St. Augustine’s Flat @ St. Marys Mayo Clinic!

St Augustine Flat is the best place in town to stay. Unmatched location and space, save $$. Located in the prestigious “Pill Hill” walking distance to all of downtown Rochester, 1 block from St. Marys Hospital (in the background of pic). From St Marys catch the free Mayo Shuttle to other Mayo locations. Beautiful hardwood floors, 1 bedroom with walk-in closet, full bath, Kitchen, Fast WiFi, Smart Tv. The space is upstairs. The stairs are steep with narrow tread! I look forward to hosting you!

4.98 out of 5 average rating, 327 reviews

A charming two-story structure is shown with a welcoming red exterior and a large wrap-around covered deck. Brightly colored flower pots accent the porch, and two decorative wagon wheels enhance the façade. Well-maintained grass and a concrete path lead to the entrance.

Guest suite in Rochester

Porch on 4th

Welcome to your home, away from home. Private, Clean & Comfortable ! 1200 square feet in a 2nd floor apartment with 2 bedrooms & spacious living area. We are a 5 minute drive to downtown Mayo Clinic, St. Mary's Hospital & many shopping areas. Walking distance to convenience store. We are in an easy access area to get to the many things Rochester has to offer. Inspected & licensed as rental property by the City of Rochester. Smoke free. We allow service animals & 1 small dog under 25 pounds.

A spacious living area features warm wood beam ceilings and large windows, allowing natural light to fill the room. Modern furniture, including a comfortable white sofa and a glass dining table, is arranged to create an inviting space. Double doors lead to a backyard patio.

4.95 out of 5 average rating, 260 reviews

Euro House, Bright! Near Mayo-Single Family Home

Welcome to your home away from home! This private, single-family home was thoughtfully designed and is located in a quiet area just 5 minutes (0.9 miles) from the Mayo Clinic. Step into a master gardener’s dream—a beautifully landscaped yard filled with native plants and outdoor seating, perfect for relaxing after a long day. 2 Queen Bedrooms, 2 Full Bathrooms, modern finishes throughout, Super clean and pet-free. Off-street parking, Washer & dryer, Wi-Fi, Smart TVs & Fully stocked kitchen.

A cozy bedroom features a spacious bed with neatly arranged pillows and a navy throw blanket. Two lamps illuminate the nightstands flanking the bed. Wall art and a large mirror enhance the inviting atmosphere, while natural light filters in through nearby windows.

4.93 out of 5 average rating, 168 reviews

Home for the Traveler, a walk to St. Mary's

This place is located near the heart of Rochester, within blocks of St. Mary's hospital, very peaceful, cozy and private. A lower-level unit in an older home, plenty of windows and light, and includes a gorgeous bedroom with a fireplace, a full kitchen, a reading room, and a clean, updated bathroom. This home is also close to the Apache mall, the Canadian Honker and other local restaurants, coffee shops, and the walking/biking trail system. There is also Wi-Fi, laundry, and parking on-site.

A single-story home is shown, featuring a red front door and a well-maintained exterior. Vibrant autumn trees with golden leaves line the walkway, and a grassy area is depicted in front of the house, inviting a sense of tranquility to the setting.

4.87 out of 5 average rating, 396 reviews

Mayo Downtown's Prairie Home Retreat

Nestled in a serene corner, this home offers a perfect blend of tranquility and accessibility; being near the Mayo campus and Rochester's key attractions. Enjoy comfortable beds, a well-appointed kitchen, and a fenced yard with patio gardens. It's an excellent spot for family bonding, featuring three smart TVs, rapid Wi-Fi, and a variety of indoor and outdoor entertainment options. We strive to accommodate flexible check-in/check-out arrangements whenever feasible. Rollator accessible.

A cozy living room space features a beige couch adorned with decorative pillows and a low coffee table. The white brick wall serves as a backdrop for a fireplace, which is framed by a wooden mantle decorated with artwork and a wreath. Natural light enters through a window.

4.97 out of 5 average rating, 264 reviews

Restful sanctuary close to Mayo Clinic

This cozy space has private, self-entrance with off-street parking at no cost...a mere 2.5 miles or 10 minute drive to the Mayo Clinic downtown. Located in a quiet neighborhood in northwest Rochester. Easy access to highways, grocery store, coffee shop, Target, restaurants and biking/walking trail. Completely furnished with linens, hair-dryer, Netflix and Hulu, Smart TV and Wi-fi....and a Keurig Coffee maker with enough coffee pods to get you started. Truly, a home away from home!

Home in Historic Southwest

The open-concept living area showcases vaulted ceilings and skylights, enhancing natural light. Two light grey sofas frame a wooden coffee table on a colorful area rug. A dining area with a large table and chairs is visible, with stairs leading to the upper level in the background.

4.97 out of 5 average rating, 191 reviews

Spacious Modern Home Near Mayo, St. Mary's Campus

- 5 min walk to Mayo Clinic, St. Mary’s campus - 3 bedrooms, 3 bathrooms, and a loft - unique design with vaulted ceiling and skylights in the style of Frank Lloyd Wright, one of its kind in the whole neighborhood - two-car garage + another dedicated parking space outside - walkable and safe family-friendly neighborhood close to downtown and all amenities - outside front and back patios - fusball play table - dedicated workspace - high speed wifi - Apple TVs - washer and dryer

4.96 out of 5 average rating, 134 reviews

The living area is highlighted by a modern gray sofa, accentuated with textured cushions. A sleek coffee table holds a glass vase with greenery, while art pieces adorn the wall. Natural light filters through sheer curtains, creating a bright and inviting space.

Home in Kutzky

Entire Boutique Home Kutzky Park ★ Walk to Mayo ★

Welcome to Asfar house! Expertly designed and centrally-located in a desirable Kutzky Park neighborhood, walking distance to Mayo Clinic, restaurants and shops. Whether you are relocating or visiting Rochester, this house will be sure to impress. Blasting fast WIFI, 3 relaxing bedrooms & a fully equipped kitchen. A perfect retreat to enjoy the coffee bar, read, watch a Netflix episode, play and relax. Enjoy the perfect shower, conveniently adjoined with free washer and dryer.

A dining area features a wooden table set with beige dishes and coffee cups, surrounded by dark wooden chairs. In the background, a kitchen is seen with a white refrigerator, microwave, and gas stove. A cozy living room with a reclining loveseat is partially visible.

4.87 out of 5 average rating, 243 reviews

SALE: Remodeled retreat near Mayo Clinic

• Enhanced cleaning protocols due to COVID • Fully renovated apartment in summer 2018 • 650 square feet • Upstairs apartment in quiet 4plex • Free off-street parking • 5 blocks north of Mayo Clinic • Walk-in tiled shower • Queen bed • Full kitchen with gas stove (new 5/16/19) • Reclining leather loveseat • 43" Smart TV with DirecTV/cable • High-speed WiFI — 300 MBPS • Shared laundry in the basement • Huge windows for tons of natural light

4.96 out of 5 average rating, 160 reviews

The Sierra! Close to Mayo Clinic

Gorgeous Home close to Mayo Clinic. The family room and living include Roku 4K UHD TVs, Foosball, and darts. Free WIFI. Office on Main with great light. Beautiful front porch or patio in the rear. TVs Enjoy luxurious finishes like crown molding, a fireplace in the family room, quartz countertops and a stunning vaulted Primary Ensuite with custom tile work and paneled doors. All of this is conveniently just minutes from downtown!

Popular amenities for Rochester family-friendly rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Family-friendly home rentals with a hot tub

A light-filled living room features a soft beige sofa with blue accent pillows. Two teal chairs with decorative pillows are positioned nearby. A small coffee table is centered in the room, with a mirror and lamps providing ambient lighting. Large windows offer views of the outside.

5 out of 5 average rating, 5 reviews

Gorgeous Rochester-Mayo Clinic Home

A living area showcases a coffee table with a glass top, positioned in front of a mounted television. Floral-patterned curtains frame a window, while a small vase with flowers and a box are placed on the table, enhancing the inviting atmosphere of the space.

4.67 out of 5 average rating, 9 reviews

Elegant &Secure Family Abode

New place to stay

Modern Cozy house, near Mayo Clinic

A spacious studio apartment is showcased with large windows that allow natural light to fill the room. A comfortable bed sits on one side, complemented by a stylish seating area featuring two chairs. Soft textures are present with a plush rug, enhancing the modern aesthetic.

Guesthouse in Rochester

Private Stay Away From It All

4.99 out of 5 average rating, 77 reviews

A rustic log cabin is framed by a lush green lawn, complemented by a natural stone chimney. A covered porch extends across the front, with large windows allowing ample light into the structure. Nearby greenery and trees add to the serene outdoor setting.

Cabin in Wykoff

Rochester Luxury Log cabin Whispering Oaks Retreat

A well-maintained pathway leads to a welcoming entrance of the home, bordered by lush greenery and colorful flowers. The front porch, featuring comfortable seating, is shaded by a large overhang, while a lamp post adds gentle illumination to the landscaped yard.

5 out of 5 average rating, 22 reviews

Beautiful, Private, Nature & Hot tub! 4m to Mayo

New place to stay

Skyway connected Extended Stay in Rochester

A serene outdoor space is highlighted by a stunning sunset over lush greenery. Comfortable seating is arranged around a fire pit, surrounded by blooming flowers and various plants. A swimming pool is visible in the background, nestled into the landscape.

5 out of 5 average rating, 47 reviews

RARE! Pool, hot tub, garden &chickens! 4m to Mayo

Family- and pet-friendly home rentals

Apartment in Downtown Rochester

A modern kitchen area features stainless steel appliances, including a refrigerator and a built-in oven. A central island with bar seating for four is surrounded by warm wooden cabinetry and contemporary finishes. A doorway leads to a cozy sleeping area in the background.

5 out of 5 average rating, 4 reviews

Peaceful Riverfront 2Bed/2Bath w/Balcony near Mayo

An inviting living room features a dark sofa, a patterned armchair, and a coffee table at its center. Artwork adorns the walls, while light streams in through a window covered with curtains. A cozy area rug adds warmth to the wooden floor.

4.95 out of 5 average rating, 65 reviews

Come From Away!

An open-concept living area features a dining table with wooden chairs at the forefront. Beyond, a well-equipped kitchen is visible, alongside a cozy seating area with a sofa. Recessed lighting illuminates the space, enhancing the welcoming atmosphere.

4.97 out of 5 average rating, 90 reviews

Spacious 2BR Flamingo Suite - Minutes From Mayo

A welcoming living room is highlighted by a vibrant flower arrangement on a gold side table. A cozy couch faces a fireplace, with a television mounted above a white entertainment center. Musical decor and seasonal garlands add a touch of charm to the space.

4.86 out of 5 average rating, 36 reviews

Discount Charming 2 Bedroom Close to Mayo

4.98 out of 5 average rating, 130 reviews

Bungalow in Rochester

Betty’s Bungalow: A Dharma Dwellings Home

5 out of 5 average rating, 54 reviews

The Don

4.95 out of 5 average rating, 178 reviews

A log home with a red roof and green accents is surrounded by trees and grass. A front porch with a welcoming entrance features a decorative wreath, and a spacious driveway leads to a garage. Sunlight bathes the exterior in bright colors.

Home in Stewartville

"Walden Pond" Adventure Amidst 44 Private Acres

The exterior of the home features a charming design with a light-colored facade and natural stone accents. A neatly trimmed lawn is complemented by a walkway leading to the front entrance. The property is framed by bare trees and a wooden fence in the background.

4.92 out of 5 average rating, 109 reviews

Character & Comfort on 7th Ave

Family-friendly home rentals with a pool

An open living area showcases a gray sofa and a green chair, complemented by a round wood coffee table. Two framed artworks are displayed on the light-colored wall, while modern kitchen appliances are visible in the background, illuminated by soft natural light.

4.08 out of 5 average rating, 12 reviews

Two Bedroom Luxury in Rochester

4.81 out of 5 average rating, 31 reviews

A modern bathroom is equipped with a spacious vanity featuring a large mirror and ample storage. A bathtub with a shower unit is present, along with a white toilet. Soft towels are neatly arranged on a rack, highlighting a clean and functional space.

Apartment in Kutzky

Studio Apartment

An open kitchen area features modern appliances, including a stove and refrigerator. A large island with seating provides a central gathering space. Natural light floods the living area through sliding glass doors, which lead to an outdoor patio with green views.

4.83 out of 5 average rating, 6 reviews

Luxury 1 bedroom Serenity

A modern single-family home showcases a dark exterior with a spacious two-car garage. The front yard is neatly landscaped, featuring green grass and a young tree. A covered porch provides shaded entry, with large windows allowing natural light to stream indoors.

5 out of 5 average rating, 12 reviews

Unit 2365J | 2bd/2bth | Single-Family Home

5 out of 5 average rating, 3 reviews

Lux 1 BR I 1 Block to Mayo Skyway I Parking I Pets

The exterior of a modern two-story home showcases a contrasting black and white color scheme. A spacious driveway leads to a large, white garage door. Clear blue skies serve as a backdrop, and well-maintained landscaping frames the property.

4.86 out of 5 average rating, 7 reviews

4bd/2.5bth Single-Family Home Close to Mayo

4.92 out of 5 average rating, 96 reviews

A modern multi-story building is displayed, featuring large glass windows and a combination of brick and smooth facade materials. The entrance is framed by a wide overhang, and surrounding trees add greenery to the welcoming exterior.

Apartment in Kutzky

2 bdrm Furnished Apt Across from Saint Marys Hosp