Apartment vacation rentals in Rochester

Extended Stay Suite Near Mayo Clinic

Stay comfortably in Rochester with all the conveniences of home. Whether you're visiting Mayo Clinic, traveling for work, relocating, or simply exploring the area, this bright and modern furnished suite offers everything needed for a stress-free stay. Enjoy a living space filled with natural light, fully equipped kitchen with full-size appliances, and an in-suite washer and dryer. WiFi, comfortable furnishings, and thoughtful spaces make this suite ideal for both short visits and extended stays.

Woodland Retreat, Full private walkout lower level

Peaceful retreat down gravel driveway 15 min from Mayo Clinic. Enjoy your own apartment with private backyard walkout entrance to the lower level of our home. You will have a bedroom, living area, kitchenette with mini fridge, microwave and toaster oven (no conventional stove/oven), bathroom w/ tub & shower, pingpong table, laundry, and patio with fire ring. You may hear piano music weekday afternoons, since I give lessons (usually 3-6 pm; a bit earlier in summer) NEW HEATED FLOORS w/thermostat

Upscale King Suite—Steps from Mayo Clinic Hospital

This luxury suite is a private wing on the 2nd floor of a newly renovated 3-story mansion. Conveniently located in one of the trendiest neighborhoods in Rochester. Steps from the Mayo Clinic St. Mary's hospital, Starbucks & Caribou coffee, restaurants, grocery stores, nightlife & downtown. FEATURES High speed internet 75” HD LED TV Workspace High-end interior King size beds Washer/dryer Fully stocked kitchen Free garage parking Keyless entry Super convenient for short-term or long-term stays.

Fresh space near Mayo Clinic and downtown

Minutes away from downtown shops, restaurants, and Mayo Clinic, this main-level apartment is newly-renovated, cheerful, and ready for your arrival. The open living/dining area feels spacious and bright, with two picture windows letting in lots of natural light. Enjoy two private bedrooms, each with a queen-sized bed. Fully-equipped kitchen makes for efficient cooking and baking. Bus stop less than a block away. Trails nearby. From May-Oct, visit the local Farmer's Market at Graham Park.

Modern Comfort Stay | 2BR | Close to Mayo

Comfortable, modern 2BR lower-level unit just 5 minutes from Mayo Clinic perfect for patients, families, and traveling professionals. Enjoy a cozy living room with Smart TV, two private bedrooms, a walk-in shower, and in-unit washer/dryer. No stairs, easy access, with a bus stop right nearby. Fast WiFi included. Easy street parking right by your private entrance. Located in a quiet residential area with quick access to shops and dining. Note: duplex with tenants upstairs; light noise possible.

Relaxing, spacious, upper 2BR, sun room, loft.

This is a Very spacious upper level apartment in a triplex that with steps to access the apartment. It has 2 bedrooms, a sun room/eating area, large living room, bath just updated, large kitchen and a loft upstairs 1225 sq. ft.) . The kitchen is fully equipped with all necessities for making your own meals. All rooms have lots of windows and light. This unit is in the Kutzky Park neighborhood. It is very quiet and safe and only 4 blocks to Mayo and downtown with restaurants and grocery stores.

Lux 1 BR I 1 Block to Mayo Skyway I Parking I Pets

Welcome to your luxury refined home base in the heart of downtown Rochester. Located at The Maven on Broadway, this upscale one-bedroom apartment offers the perfect blend of comfort, convenience, and elevated living—just a short walk to the skyway connecting you in minutes to the Mayo Clinic System. Whether you’re here for medical care, professional work, or supporting a loved one, this thoughtfully designed space provides a calm, stylish space with all the amenities needed during your stay.

Summer Special-2 Bedroom Close to Mayo Clinic

Peaceful and centrally located cottage. This home is a beautifully furnished main-level triplex just 5 minutes from Mayo Clinic. Bus stop on property and multiple restaurants 3 minutes away. This 2-bedroom, 1-bath unit has everything you might need to recover from a surgery, to feel at home while seeking treatment or to enjoy beautiful Rochester. The house is child friendly with a nice selection of toys and books to keep the little ones occupied. Pets welcome at a charge of $50/pet/month.

|Rochester S-E Gem| Airbnb Special!

Welcome to our privately owned - home base Airbnb unit in the heart of Rochester, MN where comfort meets unbeatable charm and convenience! What can you expect? Very CLEAN and modified unit that meets all your expectations, perfectly located less than a mile from the Mayo Clinic! This amazing place is just a quick 5-min drive (or an easy 20-minute walk) to the Mayo Clinic, making it an ideal stay for medical travelers, medical professionals, or a day out and about near the HEART of Rochester!

Cozy Clinic Retreat

Fully remodeled 1 bedroom, 1 bath unit with an office offering comfort and flexibility. The modern kitchen features quartz countertops while the bright living room is perfect for relaxing, watching TV, or playing board games. The bathroom includes a tub and tiled shower, and the bedroom offers a large closet. The office has a desk and chair, plus an air mattress for a third guest. Two driveway parking spaces included. Located four blocks from Mayo Clinic and just steps from the bus line.

The Gwen | 2BR Apt, Fenced Yard, Pets, <3mi Mayo

A fully furnished 2-bed, 1.5-bath upstairs apartment with its own attached fenced yard and patio — a favorite for guests traveling with a dog. Full kitchen, dining area, living room, and a dedicated workspace for remote work. Free parking, quiet neighborhood feel, under 3 mi from Mayo and downtown. • 2 BR / 2 beds / 1.5 baths · sleeps 4 • Fenced yard + patio · workspace • Pet-friendly · free parking • Under 3 mi to Mayo Want the whole building? Book "Century Noll" for both units.

SALE: Remodeled retreat near Mayo Clinic

• Enhanced cleaning protocols due to COVID • Fully renovated apartment in summer 2018 • Brand new kitchen in March 2026 • 650 square feet • Upstairs apartment in quiet 4plex • Free off-street parking • 5 blocks north of Mayo Clinic • Walk-in tiled shower • Queen bed • Oversized power recline La-Z-Boy chair • Reclining leather loveseat • 43" Smart TV with DirecTV/cable • High-speed WiFI — 300 MBPS • Shared laundry in the basement • Huge windows for tons of natural light