
Apartment vacation rentals in Rochester
Find and book unique apartments on Airbnb
Quick stats about apartment rentals in Rochester

Total vacation rentals
Explore 110 vacation rentals in Rochester

Nightly prices starting at
Rochester vacation rentals start at G$4,180 GYD per night before taxes and fees

Verified guest reviews
Over 5,650 verified reviews to help you choose

Family-friendly vacation rentals
50 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 30 rentals that welcome pets

Rentals with dedicated workspaces
70 properties have a dedicated workspace

Wi-Fi availability
110 of Rochester vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Rochester rentals

4.8 Average rating
Rochester stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated apartment rentals in Rochester
Guests agree: these apartments are highly rated for location, cleanliness, and more.

Oasis Luxe Suite—Steps from Mayo Clinic Hospital
This luxury suite is a private wing on the lower level of a newly renovated 4-level mansion. Conveniently located in one of the trendiest neighborhoods in Rochester. Steps from the Mayo Clinic St. Marys hospital, Starbucks & Caribou coffee, restaurants, grocery stores, nightlife & downtown. FEATURES High speed internet 55” HD LED TV Workspace High-end interior Queen size beds Washer/dryer Fully stocked kitchen Free garage parking Keyless entry Super convenient for short-term & long-term stays.

Woodland Retreat, Full private walkout lower level
Peaceful retreat down gravel driveway 15 min from Mayo Clinic. Enjoy your own apartment with private backyard walkout entrance to the lower level of our home. You will have a bedroom, living area, kitchenette with mini fridge, microwave and toaster oven (no conventional stove/oven), bathroom w/ tub & shower, pingpong table, laundry, and patio with fire ring. You may hear piano music weekday afternoons, since I give lessons (usually 3-6 pm; a bit earlier in summer) NEW HEATED FLOORS w/thermostat

Fresh space near Mayo Clinic and downtown
Minutes away from downtown shops, restaurants, and Mayo Clinic, this main-level apartment is newly-renovated, cheerful, and ready for your arrival. The open living/dining area feels spacious and bright, with two picture windows letting in lots of natural light. Enjoy two private bedrooms, each with a queen-sized bed. Fully-equipped kitchen makes for efficient cooking and baking. Bus stop less than a block away. Trails nearby. From May-Oct, visit the local Farmer's Market at Graham Park.

Relaxing, spacious, upper 2BR, sun room, loft.
This is a Very spacious upper level apartment in a triplex that with steps to access the apartment. It has 2 bedrooms, a sun room/eating area, large living room, bath just updated, large kitchen and a loft upstairs 1225 sq. ft.) . The kitchen is fully equipped with all necessities for making your own meals. All rooms have lots of windows and light. This unit is in the Kutzky Park neighborhood. It is very quiet and safe and only 4 blocks to Mayo and downtown with restaurants and grocery stores.

Lux 1 BR I 1 Block to Mayo Skyway I Parking I Pets
Welcome to your luxury refined home base in the heart of downtown Rochester. Located at The Maven on Broadway, this upscale one-bedroom apartment offers the perfect blend of comfort, convenience, and elevated living—just a short walk to the skyway connecting you in minutes to the Mayo Clinic System. Whether you’re here for medical care, professional work, or supporting a loved one, this thoughtfully designed space provides a calm, stylish space with all the amenities needed during your stay.

Summer Special-2 Bedroom Close to Mayo Clinic
Peaceful and centrally located cottage. This home is a beautifully furnished main-level triplex just 5 minutes from Mayo Clinic. Bus stop on property and multiple restaurants 3 minutes away. This 2-bedroom, 1-bath unit has everything you might need to recover from a surgery, to feel at home while seeking treatment or to enjoy beautiful Rochester. The house is child friendly with a nice selection of toys and books to keep the little ones occupied. Pets welcome at a charge of $50/pet/month.

|Rochester S-E Gem| Airbnb Special!
Welcome to our privately owned - home base Airbnb unit in the heart of Rochester, MN where comfort meets unbeatable charm and convenience! What can you expect? Very CLEAN and modified unit that meets all your expectations, perfectly located less than a mile from the Mayo Clinic! This amazing place is just a quick 5-min drive (or an easy 20-minute walk) to the Mayo Clinic, making it an ideal stay for medical travelers, medical professionals, or a day out and about near the HEART of Rochester!

The Gwen | 2BR Apt, Fenced Yard, Pets, <3mi Mayo
A fully furnished 2-bed, 1.5-bath upstairs apartment with its own attached fenced yard and patio — a favorite for guests traveling with a dog. Full kitchen, dining area, living room, and a dedicated workspace for remote work. Free parking, quiet neighborhood feel, under 3 mi from Mayo and downtown. • 2 BR / 2 beds / 1.5 baths · sleeps 4 • Fenced yard + patio · workspace • Pet-friendly · free parking • Under 3 mi to Mayo Want the whole building? Book "Century Noll" for both units.

SALE: Remodeled retreat near Mayo Clinic
• Enhanced cleaning protocols due to COVID • Fully renovated apartment in summer 2018 • Brand new kitchen in March 2026 • 650 square feet • Upstairs apartment in quiet 4plex • Free off-street parking • 5 blocks north of Mayo Clinic • Walk-in tiled shower • Queen bed • Oversized power recline La-Z-Boy chair • Reclining leather loveseat • 43" Smart TV with DirecTV/cable • High-speed WiFI — 300 MBPS • Shared laundry in the basement • Huge windows for tons of natural light

Restful sanctuary close to Mayo Clinic
This cozy space has private, self-entrance with off-street parking at no cost...a mere 2.5 miles or 10 minute drive to the Mayo Clinic downtown. Located in a quiet neighborhood in northwest Rochester. Easy access to highways, grocery store, coffee shop, Target, restaurants and biking/walking trail. Completely furnished with linens, hair-dryer, Netflix and Hulu, Smart TV and Wi-fi, and coffee maker. The laundry is shared with the host. Truly a home away from home!

Beautiful Duplex home 5 minute walk to Mayo Clinic
This home is located in the heart of the historic Rochester, MN. Just a stones throw from the Mayo Clinic. This downtown area is packed with shops and eating establishments, all interconnected via the walking subway system, for those cold winter days. When the weather warms, beautiful parks and paths abound in an endless display of green natural space. I hope your travels are safe and look forward to meeting you.

Apt A ! Close to Dn town and mayo clinic and Gonda
Apt A ! only 5 minit s from Mayo clinic and Gonda ! Main lower level 1 queen sized bedroom 1 single bedroom can sleep 3 guests but thats with 2 people in the queen bed and 1 in the twin bed but if your party can not share beds then sum one will have to use the couch ? living space set up for housekeeping 9 block s from mayo clinic n down town shop s and fine dining !
Popular amenities for Rochester apartment rentals
Weekly apartment rentals

Magical Nest

One bedroom Apt walk to Mayo and St,Mary's.

Scandinavian Retreat, Cozy 2BD, 1 Mile to Mayo

Lavish Suit

Luxury updated two bedroom apt

Cozy, Private, near Mayo and Pet-friendly

Relaxing, main floor apartment in 4plex, #2.

Safe Temporary Emergency or Homeless Prevention
Private apartment rentals

8076-WALK to Mayo-Charming Studio Apt Free Parking

Step to Mayo Clinic | Free Parking | Private Unit

EXCEPTIONAL, CONTEMPORARY 2BD/1 BA/ CLOSE TO MAYO

2 Bed 1 Bath condo - Mayo clinic

All you need! Close to Mayo/Downtown/Fairgrounds.

Home for the Traveler, a walk to St. Mary's

Cozy Clinic Retreat

3 Bedroom Discounted 5-Star Duplex 5 Mins to Mayo
Apartment rentals with a hot tub

Luxury 1BR Apartment · Steps to Mayo Clinic | A-2

Luxury 1BR Apartment · Steps to Mayo Clinic | A-1

Luxury 1BR Apartment - Steps to Mayo Clinic | G-2

Luxury 1BR Apartment · Steps to Mayo Clinic | E

Skyway connected Extended Stay in Rochester

Luxury 1BR Apartment · Steps to Mayo Clinic | G
When is the best time to visit Rochester?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$14,420 GYD | G$14,211 GYD | G$14,629 GYD | G$14,838 GYD | G$15,883 GYD | G$16,719 GYD | G$17,137 GYD | G$16,719 GYD | G$15,674 GYD | G$15,674 GYD | G$15,256 GYD | G$14,420 GYD |
| Avg. temp | -10°C | -7°C | 0°C | 7°C | 14°C | 20°C | 21°C | 20°C | 16°C | 9°C | 1°C | -6°C |
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