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Apartment vacation rentals in Rochester

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Rochester

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Top guest favorite
The modern living area features a comfortable blue sofa adorned with a patterned throw. Two orange accent chairs complement a coffee table at the center. A large wall-mounted TV is visible, while soft lighting creates an inviting atmosphere. The open-concept space connects to the kitchen area.
Apartment in Kutzky
5 out of 5 average rating, 19 reviews

Penthouse Suite—Steps from Mayo Clinic Hospital

This luxury suite is a private wing on the 3rd floor of a newly renovated 3-story mansion. Conveniently located in one of the trendiest neighborhoods in Rochester. Steps from the Mayo Clinic St. Mary's hospital, Starbucks & Caribou coffee, restaurants, grocery stores, nightlife & downtown. FEATURES High speed internet 75” HD LED TV Workspace High-end interior King size beds Washer/dryer Fully stocked kitchen Free garage parking Keyless entry Super convenient for short-term or long-term stays.

Top guest favorite
A garden-level apartment is accessed via a gravel driveway that leads to a charming home. Lush greenery surrounds the path, and the structure features a mix of siding colors, with large windows framed by blue shutters, creating an inviting exterior appearance.
Apartment in Rochester
4.93 out of 5 average rating, 210 reviews

Woodland Retreat, Full private walkout lower level

Peaceful retreat down gravel driveway 15 min from Mayo Clinic. Enjoy your own apartment with private backyard walkout entrance to the lower level of our home. You will have a bedroom, living area, kitchenette with mini fridge, microwave and toaster oven (no conventional stove/oven), bathroom w/ tub & shower, pingpong table, laundry, and patio with fire ring. You may hear piano music weekday afternoons, since I give lessons (usually 3-6 pm; a bit earlier in summer) NEW HEATED FLOORS w/thermostat

Guest favorite
A welcoming living room is highlighted by a vibrant flower arrangement on a gold side table. A cozy couch faces a fireplace, with a television mounted above a white entertainment center. Musical decor and seasonal garlands add a touch of charm to the space.
Apartment in Rochester
4.86 out of 5 average rating, 36 reviews

Discount Charming 2 Bedroom Close to Mayo

Peaceful and centrally-located cottage. This home is a beautifully furnished main-level duplex just 5 minutes from Mayo Clinic. Bus stop on property and multiple restaurants 3 minutes away. This 2-bedroom, 1-bath unit has everything you might need to recover from a surgery, to feel at home while seeking treatment or to enjoy beautiful Rochester. The house is child friendly with a nice selection of toys and books to keep the little ones occupied. Pets welcome at a charge of $50/pet per month.

Top guest favorite
A cozy bedroom features a spacious bed with neatly arranged pillows and a navy throw blanket. Two lamps illuminate the nightstands flanking the bed. Wall art and a large mirror enhance the inviting atmosphere, while natural light filters in through nearby windows.
Apartment in Rochester
4.93 out of 5 average rating, 167 reviews

Home for the Traveler, a walk to St. Mary's

This place is located near the heart of Rochester, within blocks of St. Mary's hospital, very peaceful, cozy and private. A lower-level unit in an older home, plenty of windows and light, and includes a gorgeous bedroom with a fireplace, a full kitchen, a reading room, and a clean, updated bathroom. This home is also close to the Apache mall, the Canadian Honker and other local restaurants, coffee shops, and the walking/biking trail system. There is also Wi-Fi, laundry, and parking on-site.

Guest favorite
A modern bathroom is showcased, featuring a round mirror above a sleek vanity with a dark finish. A light fixture with three bulbs illuminates the space. A patterned shower curtain complements the design, while a soft area rug adds an element of comfort.
Apartment in Downtown Rochester
4.89 out of 5 average rating, 104 reviews

Rochester Home (Duplex) 5 min walk to Mayo

This home is located in the heart of the historic Rochester, MN. Just a stones throw from the Mayo Clinic. This downtown area is packed with shops and eating establishments, all interconnected via the walking subway system, for those cold winter days. When the weather warms, beautiful parks and paths abound in an endless display of green natural space. If you find yourself here in the summer you are welcome to my organic garden. I hope your travels are safe and look forward to meeting you.

Guest favorite
A two-story duplex is presented, featuring a symmetrical facade with bay windows and a front porch. A well-maintained lawn and landscaping enhance the entrance, which includes a set of white steps leading up to the front door. Clear blue skies create a bright atmosphere.
Apartment in Historic Southwest
4.95 out of 5 average rating, 39 reviews

Next to Mayo Clinic 518A.

Welcome to our cozy home in Rochester’s historic Southwest neighborhood! We’re right across from the Mayo Clinic Downtown Campus and just four blocks from St. Mary’s Hospital—perfect for Mayo patients, visitors, or staff. This main-floor, two-bedroom unit features WiFi, FuboTV, a smart lock, and free use of a washer and dryer. Free parking is included, with space for a camper if arranged in advance. The area is quiet, safe, and mostly home to medical professionals. We’d love to host you!

Top guest favorite
A well-appointed bedroom features a spacious bed with a textured blue coverlet. Nightstands flank the bed, each with a lamp providing soft illumination. Light-colored curtains frame the oversized window, allowing natural light to brighten the warm hardwood floors.
Apartment in Rochester
4.89 out of 5 average rating, 182 reviews

NEW: Calming main floor retreat near Mayo Clinic

• Enhanced cleaning protocols due to COVID • Fully renovated apartment in winter 2019 • Main floor apt in quiet 4plex • 550 square feet with refinished hardwood floors throughout • La-Z-Boy power recline loveseat with power headrests and USB ports. Both sides also rock. • 65" Smart TV with DirecTV • Free off-street parking • 6 blocks north of Mayo Clinic • Walk-in shower • Queen bed • Full kitchen with gas stove and dishwasher • High-speed WiFI — 100+ MBPS • Shared laundry in basement

Top guest favorite
A cozy living room space features a beige couch adorned with decorative pillows and a low coffee table. The white brick wall serves as a backdrop for a fireplace, which is framed by a wooden mantle decorated with artwork and a wreath. Natural light enters through a window.
Apartment in Rochester
4.97 out of 5 average rating, 258 reviews

Restful sanctuary close to Mayo Clinic

This cozy space has private, self-entrance with off-street parking at no cost...a mere 2.5 miles or 10 minute drive to the Mayo Clinic downtown. Located in a quiet neighborhood in northwest Rochester. Easy access to highways, grocery store, coffee shop, Target, restaurants and biking/walking trail. Completely furnished with linens, hair-dryer, Netflix and Hulu, Smart TV and Wi-fi....and a Keurig Coffee maker with enough coffee pods to get you started. Truly, a home away from home!

Superhost
The kitchen features modern cabinetry and stainless steel appliances, including a microwave, oven, and dishwasher. A spacious countertop offers ample preparation space, while a stainless steel sink is positioned under a window inviting natural light. Cooking essentials and utensils are neatly arranged.
Apartment in Rochester
4.79 out of 5 average rating, 28 reviews

Remodeled 2nd-floor apartment blocks from Mayo

Completely remodeled 2nd floor apartment that is nine blocks from downtown Rochester, Mayo Clinic, restaurants, and shops. Two bedrooms, one bath--with toasty-warm heated floor! Enjoy a well-equipped kitchen, living room with Smart TV for streaming apps, private deck, garage to park your vehicle, and on-site laundry. We are located near the biking/walking trail system, park/playground, and bus stop. You're on the edge of the urban buzz on 4th Street SE, a busy thoroughfare.

Guest favorite
A modern kitchen is shown with stainless steel appliances, including a refrigerator and wall oven. The island features a light countertop, accompanied by two bar stools. Cabinets are installed above and below, ensuring ample storage space. Natural light fills the area through the adjacent windows.
Apartment in Downtown Rochester
5 out of 5 average rating, 8 reviews

Tranquil 2Bed/2Bath w/Balcony near Mayo

Welcome to The Lofts at Mayo Park, a river-view apartment nestled along the scenic Zumbro River in Rochester, MN. Offering the perfect blend of modern elegance and tranquility, this upscale stay is just minutes from downtown and the Mayo Clinic yet tucked away in a peaceful, private setting. Tenants may be seen lounging on the front porch, listening to drifting notes from the piano, and visiting the surrounding parks, riverside trails, and community facilities!

Guest favorite
Apartment in Rochester
5 out of 5 average rating, 5 reviews

Viola Suite #1 | 1 bed, 1.5 Bath, Pets Welcome

Spacious, pet-friendly home less than 3 miles from Mayo Clinic downtown campus! Features a king bed with attached workspace, 1.5 baths, cozy living room with smart TV, dining area, and full kitchen. Easy access with only 2 steps to enter and no steps inside. Enjoy the large shared yard, coin laundry, and free off-street parking. Quiet, economical, and accessible — perfect for medical visits, work trips, or a comfortable stay.

Guest favorite
A two-story house with gray siding and red trimmed accents is situated on a landscaped corner lot. Well-maintained bushes and flowerbeds surround the property, and a small set of steps leads to the front entrance. Nearby, a bright orange fire hydrant is visible.
Apartment in Rochester
4.87 out of 5 average rating, 314 reviews

Apt A ! Close to Dn town and mayo clinic and Gonda

Apt A ! only 5 minit s from Mayo clinic and Gonda ! Main lower level 1 queen sized bedroom 1 single bedroom can sleep 3 guests but thats with 2 people in the queen bed and 1 in the twin bed but if your party can not share beds then sum one will have to use the couch ? living space set up for housekeeping 9 block s from mayo clinic n down town shop s and fine dining !

Popular amenities for Rochester apartment rentals

When is the best time to visit Rochester?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$13,818 GYDG$14,446 GYDG$14,028 GYDG$14,865 GYDG$15,912 GYDG$16,749 GYDG$17,168 GYDG$16,749 GYDG$15,703 GYDG$15,284 GYDG$14,446 GYDG$14,237 GYD
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Quick stats about apartment rentals in Rochester

  • Total vacation rentals

    Explore 140 vacation rentals in Rochester

  • Nightly prices starting at

    Rochester vacation rentals start at G$4,187 GYD per night before taxes and fees

  • Verified guest reviews

    Over 6,630 verified reviews to help you choose

  • Family-friendly vacation rentals

    60 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 50 rentals that welcome pets

  • Rentals with dedicated workspaces

    100 properties have a dedicated workspace

  • Wi-Fi availability

    140 of Rochester vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Rochester rentals

  • 4.8 Average rating

    Rochester stays are highly rated by guests—averaging 4.8 out of 5!