
House vacation rentals in Port St. Lucie
Find and book unique houses on Airbnb
Quick stats about house rentals in Port St. Lucie

Total vacation rentals
Explore 860 vacation rentals in Port St. Lucie

Nightly prices starting at
Port St. Lucie vacation rentals start at G$4,184 GYD per night before taxes and fees

Verified guest reviews
Over 22,720 verified reviews to help you choose

Family-friendly vacation rentals
560 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 310 rentals that welcome pets

Vacation rentals with a pool
350 properties feature pools

Rentals with dedicated workspaces
480 properties have a dedicated workspace

Wi-Fi availability
840 of Port St. Lucie vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Port St. Lucie rentals

4.8 Average rating
Port St. Lucie stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated house rentals in Port St. Lucie
Guests agree: these houses are highly rated for location, cleanliness, and more.

Lush Waterfront Home On Bay St. Lucie
Regale the senses in this blissful retreat with a pickle ball court and private dock. The home boasts a nautically-themed interior which leads to an outdoor heated pool and hot tub. The rental includes two homes. The main house has three large bedrooms and a pull out sofa for up to 8 guests. The pool house, which is just across the atrium with the pool, accommodates up to 4 additional guests in two bedrooms with two bathrooms. The price is for the entire property with a maximum of 12 guests.
5.0 out of 5 average rating, 103 reviews
The Riverhouse / Waterfront / Pool / Updated
Waterfront dream home with the best views of the St. Lucie River on a preserve! Completely private backyard with a dock, ocean access, and a beautiful swimming pool. The home has been fully updated and has water views from every room. Two-story home, with 3 bedrooms, and 2 bathrooms, large sports/family loft with pool table and large screen tv. Digital piano. Home is fully equipped with everything you need during your stay. Boat not included but boat rentals available upon request at extra cost.
4.98 out of 5 average rating, 82 reviews
3/2 w Heated Salt Pool Getaway on Calusa
This is your instant "home away from home". The property is located just minutes from the beach! However the brand new salt water pool makes it easy to forget the beach is so close. There is outdoor seating in the sunshine, and also located in the screened in patio area, new privacy wood fenced back yard making it perfect for enjoying the outdoors . The landscaping is also amazing, with a beautiful 30 FT Bismarck palm outside. If you are a regular vacationer this will be your new vacation spot.
4.92 out of 5 average rating, 121 reviews
Pure Living, Saltwater Pool, Low Toxin Getaway!
Experience comfort in our newly decorated two-bedroom, two-bath retreat, complete with organic mattresses for a restful sleep. Enjoy the fully equipped kitchen and relax in the living room with a pullout couch. Outside, enjoy the saltwater pool or unwind in the Jacuzzi. Your tranquil escape awaits! PS…We are doing our best to make our home as toxin free as possible including saltwater pool, toxin free cleaners, no added scents, "air scrubber" connected to AC unit. Portable Air Purifier onsite.
4.92 out of 5 average rating, 91 reviews
Riverfront Port St Lucie home with private dock.
Beautiful 3 bedroom 2 bath river front home with private dock. deep water access to the ocean bring your boat. One block away from river front park with boat ramp and nature reserve, 10 min from Oxbow reserve. 20 min from the beach. Close to Met's spring training First Data Field , all shopping is close by. Boat trailer parking available, Beautifully landscaped yard with Palm trees, Tropical themed interior design. Sleeps 6 comfortably with 2 extra air mattress and bedding for extra guests.
4.97 out of 5 average rating, 204 reviews
The Palm House
Escape to The Palm House! Featuring a brand new salt water pool, fountain, and outdoor kitchen oasis! Recently completed pool area is a tropical dream! Located just 15 minutes from the beach. Open concept great room with a chef’s kitchen and tropical views in every direction. Enjoy a true indoor outdoor South Florida experience with 20 foot sliders that open to the patio. Custom and modern touches in every room! You’ll love the lux built in bunkbeds! Stylish bedrooms with room to sleep 12.
4.98 out of 5 average rating, 147 reviews
Relaxing Beautiful 5BR w/ heated pool and Spa
Enjoy a relaxing stay at a beautiful home in sunny southern Florida. A short drive to beaches, shopping and many nature parks. Take a drive for manatee sightings, Mets baseball, visit the local brewery or stay in and enjoy the heated pool and relax in the spa. Smart TVs in every bedroom, office and family room. Fast wifi for remote work. Beverage station, pool table and exercise equipment. Pool and SPA area with grill and fire pit. Walking distance to convenience stores and restaurants.
4.95 out of 5 average rating, 121 reviews
Private Guest House
Guest House with private entrance Bedroom: Queen bed, 42" HDTV WIFI Full bath w/shower Kitchen/Living area: Sofa, table, fridge, stove, sink, micro & toaster oven Close to casual & fine dining, PGA Golf Courses, Mets Stadium, the Turnpike and I-95. Enjoy fun activities like kayaking, nature walks, paddle-boarding, museums, and fabulous beaches. Our guest house is good for couples, individuals, business travelers, weekend golfers. Contact host for additional sleeping arrangements.
4.93 out of 5 average rating, 280 reviews
Sunny Days Retreat
Welcome to the treasure coast and your home away from home. Enjoy canal wildlife in this serene neighborhood backing onto a major canal. Even though you'll swim in a lovely screened in pool, get ready to grab a beach chair and & head to the ocean just 8 miles away. Because you are close to everything, you can dine, shop, fish, see a movie or go for a walk in the nearby botanical gardens. Connect to super fast Wi-Fi to work on one of the two desks or catch up on email.
4.89 out of 5 average rating, 118 reviews
FreshStay next to Tradition
Welcome to your home away from home! Our 4 bed 2 bath single family Airbnb is the perfect spot for your next getaway. Located right next to Tradition, you'll have easy access to all the shops and restaurants this charming community has to offer. Plus, with the highway just around the corner, you'll be able to explore all the nearby attractions with ease. Inside, you'll find a spotless and comfortable space that's perfect for relaxing after a long day of adventuring.
4.91 out of 5 average rating, 184 reviews
Spacious 4 Bedroom, Heated Pool, Game Room
The whole group will enjoy easy access to everything from this centrally located place. Nestled in the heart of Port St Lucie, this 4 bedroom 2.5 bath home offers comfort and tranquility for the whole family. Check out local attractions, book a local fishing charter, or our beautiful beaches. Enjoy being only minutes away from shopping, and still located in a quiet residential neighborhood. NO EVENTS OR PARTIES We will ask you to vacate if these rules are broken.
4.98 out of 5 average rating, 56 reviews
Our Beautiful Florida Vacation Home With Pool
This 4 bedroom, 2 bath newly renovated home is centrally located just 4.5 miles (7 min) from downtown Jensen Beach and 6.5 miles (11 min) from Hutchinson Island on Florida's Treasure Coast. If you are looking for real Florida luxury living, this home is for you! Close to shops, restaurants, various attractions, Palm Beach International Airport and most importantly, the BEACH!!! Now is the time for your family to celebrate with a Florida vacation.
4.88 out of 5 average rating, 149 reviewsPopular amenities for Port St. Lucie house rentals
House rentals with a pool

Stunning 4/3 w/ Heated Pool, Water View & Arcade!
4.99 out of 5 average rating, 112 reviews
Mini-Golf*Heated Saltwater Pool*New*Lake Front!
4.97 out of 5 average rating, 233 reviews
Cozy 3BR Home with Pool
5.0 out of 5 average rating, 21 reviews
Elkhart Vacation Home
4.93 out of 5 average rating, 27 reviews
Port St. Lucie Getaway: Heated Pool & Game Room
4.91 out of 5 average rating, 69 reviews
Barefoot Bungalow - 3 BR Pool home with Hot Tub
4.87 out of 5 average rating, 23 reviews
Unique house with pool, mini-putt, wood-burning oven
5.0 out of 5 average rating, 14 reviews
Pool, Massage chair, Gameroom
4.86 out of 5 average rating, 96 reviewsWeekly house rentals

Relaxing Port St. Lucie Getaway with Lake Access
4.95 out of 5 average rating, 87 reviews
Peaceful Cozy Modern 3 Bed Home
4.97 out of 5 average rating, 101 reviews
Quiet Coastal Home • 20 Min to Beach
5.0 out of 5 average rating, 24 reviews
A Tropical Delight with screened in heated pool!
4.93 out of 5 average rating, 75 reviews
The boathouse
4.85 out of 5 average rating, 80 reviews
Adorable Stay
4.9 out of 5 average rating, 67 reviews
Home Resort Oasis One of One!
4.92 out of 5 average rating, 75 reviews
“SWEETPEA’S PARADISE”- 2/2- Key West Style Cottage
4.98 out of 5 average rating, 56 reviewsPrivate house rentals

Bowie Street Retreat - Canal Front - Outdoor Oasis
5.0 out of 5 average rating, 7 reviews
* Beautiful Pool house 2 mi to Mets Stadium PET OK
5.0 out of 5 average rating, 10 reviews
Home sweet home
4.89 out of 5 average rating, 27 reviews
Home away relaxed stays.
4.98 out of 5 average rating, 65 reviews
Villa Blue | Private Heated Pool • Sleeps 8
4.86 out of 5 average rating, 28 reviews
Luxurious & Comfy Oasis: Pool, Yard
4.84 out of 5 average rating, 25 reviews
Bayshore Heights Paradise in Port St Lucie
4.88 out of 5 average rating, 32 reviews
Port St. Lucie Retreat | Heated Pool, Fire Pit
4.9 out of 5 average rating, 52 reviewsWhen is the best time to visit Port St. Lucie?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$37,869 GYD | G$41,007 GYD | G$41,844 GYD | G$37,451 GYD | G$34,103 GYD | G$33,057 GYD | G$31,383 GYD | G$30,337 GYD | G$29,919 GYD | G$30,965 GYD | G$33,057 GYD | G$36,404 GYD |
| Avg. temp | 17°C | 18°C | 20°C | 22°C | 25°C | 27°C | 28°C | 28°C | 27°C | 25°C | 21°C | 19°C |
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- Jupiter Beach
- Sebastian Inlet
- Stuart Beach
- City Place
- Rapids Water Park
- Jetty Park
- Blind Creek Beach
- Abacoa Golf Club
- John D. MacArthur Beach State Park
- Palm Beach County Convention Center
- DuBois Park
- Palm Beach Atlantic University
- John's Island Club
- Jonathan Dickinson State Park
- Palm Beach Par 3 Golf Course
- Phil Foster Park
- Downtown Stuart
- Sebastian Inlet State Park
- Loggerhead Marinelife Center
- Palm Beach Zoo
- John Prince Park
- Elliott Museum
- Manatee Observation & Education Center
- Florida Oceanographic Coastal Center





