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Panama Canal vacation rentals

Book unique vacation rentals, houses, and more on Airbnb

Top-rated vacation rentals in Panama Canal

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

Guest favorite

Condo in Panama

4.99 out of 5 average rating, 200 reviews

Patty’s Cozy & Quiet Studio with K-bed in Casco

*TOTALLY renovated on NOV 15th 2023: new floors, modern bathroom, new design & art work* Photos to come! Best location by the “El Rey" Supermarket...Casco's only grocery store! Prime location steps away from restaurants, bars, cafes, plazas and great little breakfast places with the lovely water front promenade around the corner making it the perfect “pied-à-terre!” The studio has a fully stocked kitchen beside from the main living space. It is spacious, comfortable and tastefully decorated!

Oct 9 – 16

G$20,599 GYD per night
Guest favorite

Condo in Panamá

4.83 out of 5 average rating, 169 reviews

Luxury apartment in the heart of Casco Antiguo

This is a luxury apartment in an old renovated building, just half block from the Cathedral in Casco Antiguo. Great views of the old town and Cathedral from the balcony. Marvelous neighbourhood, with restaurants and bars and amazing scenes every few steps. Cozy apartment with two bedrooms (each with en-suite bathroom), a large living / dining room, open kitchen, visitor toilet, laundry corner -- total 107 m2 + balcony. In an ancient building, furnished and decorated to impeccable local style.

Apr 11 – 18

G$22,336 GYD per night
Guest favorite

Guesthouse in Gamboa

4.95 out of 5 average rating, 56 reviews

Gamboa Toucan Apartment casa # 126

Welcome to Gamboa! Only 35 minutes from downtown Panama, Gamboa. Situated in Soberanía National Park and on the shores of the Panama Canal, is a Mecca for Birdwatchers and Nature enthusiasts! Watch the wildlife right from the backyard of your fully equipped apartment. Feel the magic songs of thousands of birds welcoming the twilight of sunrise and dusk in this century old community. Easily explore wildlife on trials through the surrounding old growth jungle and by boat on the Panama Canal.

Jul 31 – Aug 7

G$18,202 GYD per night

Popular amenities for Panama Canal vacation rentals

Other great vacation rentals in Panama Canal

Superhost

Home in Gamboa

4.87 out of 5 average rating, 84 reviews

BirdHouse@ Gamboa Panamá Canal

Feb 26 – Mar 5

G$76,463 GYD per night
Guest favorite

Apartment in Panamá

4.92 out of 5 average rating, 36 reviews

Beautiful apartment in Casco Viejo ST. George D

Nov 18 – 25

G$28,083 GYD per night
Guest favorite

Apartment in Panamá

5.0 out of 5 average rating, 35 reviews

Espacioso y acogedor con vistas panorámicas

Jun 20 – 27

G$20,297 GYD per night
Guest favorite

Cottage in Panamá

4.94 out of 5 average rating, 17 reviews

Moderna Casa en Altos de Cerro Azul con 2 cuartos

Jun 3 – 10

G$28,587 GYD per night
Guest favorite

Condo in Panamá

4.94 out of 5 average rating, 72 reviews

CASA SAEMA -PRESTIGIOSO ATICO DUPLEX CON TERRAZAS

Aug 31 – Sep 7

G$111,441 GYD per night
Guest favorite

Villa in Panamá

5.0 out of 5 average rating, 27 reviews

Breathtaking Views Mansion w/King Beds

Feb 17 – 24

G$124,734 GYD per night
Guest favorite

Apartment in Panamá

4.85 out of 5 average rating, 27 reviews

Hermoso apart en Casco Viejo

Oct 6 – 13

G$15,539 GYD per night
Guest favorite

Cabin in Chame

4.9 out of 5 average rating, 58 reviews

Las Nubes En Chica

Jul 28 – Aug 4

G$19,440 GYD per night
Guest favorite

Apartment in Panamá

5.0 out of 5 average rating, 18 reviews

Tropicool Loft w/rooftop steps from Casco

Dec 26 – Jan 2

G$21,290 GYD per night
Guest favorite

Apartment in Panamá

5.0 out of 5 average rating, 24 reviews

Amazing experience in Casco Viejo with ocean views

Oct 13 – 20

G$21,937 GYD per night
Guest favorite

Condo in Panamá

4.94 out of 5 average rating, 34 reviews

Apartamento en PH Yoo av. Balboa

Jan 7 – 14

G$30,887 GYD per night
Guest favorite

Loft in Panamá

4.96 out of 5 average rating, 50 reviews

Canal Loft

Aug 11 – 18

G$22,373 GYD per night

Other great vacation rentals in Panama Canal

Guest favorite

Vacation home in Panama City

5.0 out of 5 average rating, 28 reviews

Luxury Apartment With Private Beach And Sea View

Apr 21 – 28

G$27,350 GYD per night
Superhost

Apartment in Panamá

4.82 out of 5 average rating, 34 reviews

Exclusivo Apartamento en yoo panama av balboa

May 23 – 30

G$23,546 GYD per night
Superhost

Apartment in Panamá

4.82 out of 5 average rating, 57 reviews

Ocean Front Apartment in the Best Location

May 31 – Jun 7

G$21,167 GYD per night
Guest favorite

Condo in Panamá

4.98 out of 5 average rating, 43 reviews

Spacious Executive 37th-Floor Quiet Apartment

Jun 16 – 23

G$26,369 GYD per night
Guest favorite

Apartment in Panama City

5.0 out of 5 average rating, 16 reviews

Luxury Mid-Century Apartment In Casco Viejo

Sep 24 – Oct 1

G$28,843 GYD per night
Guest favorite

Villa in Portobelo

5.0 out of 5 average rating, 37 reviews

Entire Villa with pool in front of beach!

Feb 28 – Mar 7

G$51,586 GYD per night
Guest favorite

Apartment in Panamá

4.97 out of 5 average rating, 78 reviews

Cozy 2 Bedroom w/ Splash Pool

Sep 8 – 15

G$27,220 GYD per night
Guest favorite

Apartment in Panamá

5.0 out of 5 average rating, 13 reviews

Apartment in the Causeway Amador

Oct 7 – 14

G$51,792 GYD per night
Guest favorite

Condo in Panamá

5.0 out of 5 average rating, 43 reviews

Cozy 2 bedroom Apt. in Panama City, Panama

Nov 9 – 16

G$12,135 GYD per night
Guest favorite

Apartment in Panamá

4.92 out of 5 average rating, 12 reviews

King Bed Suite / 280 Degree View / 500mbs WiFi

Jul 28 – Aug 4

G$60,140 GYD per night
Guest favorite

Apartment in Panamá

4.97 out of 5 average rating, 33 reviews

Alojamiento entero con parking

Oct 2 – 9

G$13,237 GYD per night
Guest favorite

Condo in Panamá

4.94 out of 5 average rating, 16 reviews

54th floor The best sea views

Jul 14 – 21

G$36,531 GYD per night

Destinations to explore

  1. Airbnb
  2. Panama
  3. Panama Canal