Vacation rentals in Panama Canal

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Top-rated vacation rentals in Panama Canal

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite

A modern living area features a comfortable sofa complemented by decorative cushions. A glass coffee table adds a sleek touch, with natural light streaming in through large windows showcasing city views. A dining table set for four is present, surrounded by stylish decor.

Condo in Bella Vista

4.98 out of 5 average rating, 106 reviews

Top 5% Favorite | City Views | Pool, Rooftop & Gym

Enjoy a spacious, modern apartment with a standing balcony offering beautiful city and mountain views, right in vibrant, local Panama City on Calle 50. Prime location near the iconic Tornillo Building. Walk to the Metro, Cinta Costera, Panama Bay, restaurants, bars, coffee shops, local eateries, and supermarkets Enjoy Wi-Fi, Smart TV, parking, pool, gym, workspace, plus an on-site restaurant, coffee shop, and rooftop bar with breathtaking 360° city views Great location & everything close by!

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Top guest favorite

A cozy living area features a bright yellow armchair beside a sleek media console. A modern television is mounted above the console, which displays green foliage. The floor is adorned with a patterned rug, while the textured stone wall adds a rustic charm to the space.

Place to stay in San Felipe

4.95 out of 5 average rating, 102 reviews

Loft en Casco Antiguo, Joya Colonial

Bienvenidos a un espacio donde la historia, el diseño y la comodidad se fusionan en uno de los barrios más emblemáticos de Panamá. Este apartamento, ubicado en el corazón del Casco Antiguo, te sumerge en la rica cultura y arquitectura colonial, mientras te ofrece todas las comodidades modernas para una estancia inolvidable. ✔ Espacioso ✔ Diseño clásico-moderno ✔ Cocina equipada ✔ Balcón privado ✔ Habitación principal de ensueño ✔ WiFi de alta velocidad y Smart TV ✔ Ubicación inmejorable

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Superhost

A modern living area features a large wave mural that enhances the space's vibrant decor. Comfortable seating arrangements include a sleek white sofa and a pair of stylish armchairs. A glass coffee table is centered among the furnishings, with tastefully arranged decorative accents.

Apartment in Bella Vista

4.91 out of 5 average rating, 330 reviews

Modern apt ocean view in heart of Panamá yoo tower

Este lugar tiene una ubicación estratégica: ¡será muy fácil planear tu visita! Ph Yoo and Arts, ubicado en Av. Balboa, súper céntrico Esta hermosa y moderna propiedad cuenta con un estilo único y una vista al mar increíble, piso alto, 2 habitaciones, 2.5 baños completos, Lavanderia, amplia terraza, luces dimeables en todo el espacio, sala comedor, sala de películas, espacio de trabajo, 3 smart tvs, 3 aires acondicionados céntrales, cocina full equipada, cristalería moderna.

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Guest favorite

A modern living area is featured, showcasing a large wall-mounted television surrounded by a lighted panel. Seating is provided by a dark sofa with decorative pillows. A round dining table is visible in the foreground, complemented by four black chairs. Tall windows offer city views.

Apartment in Panama City

4.85 out of 5 average rating, 73 reviews

Luxury Oceanfront Resort 22nd Floor View, 200°

Luxury oceanfront apartment on the 22nd floor with breathtaking panoramic views of Panama Bay, the skyline, and historic Casco Antiguo. Located on the famous Cinta Costera, this resort-style apartment offers 2 bedrooms, 2 bathrooms, luxury kitchen, 65” TVs, washer/dryer, and sleeps up to 6 guests. Enjoy spectacular sunsets from the balcony and access to infinity pool, gym, and premium amenities, just minutes from restaurants, nightlife, and Panama City’s top attractions.

LocationValueIndoor spaces

Guest favorite

A spacious living area features light wood flooring and a modern open kitchen. Two light-colored sofas surround a marble coffee table, while a dining area with a stylish table sits nearby. A spiral staircase leads to the upper level, and decorative artwork adorns the walls.

Loft in San Felipe

4.93 out of 5 average rating, 125 reviews

Loft 3b Casco Antiguo Best! Son 150 m2 (492 feet)

Sumérgete en el encanto histórico y la elegancia moderna de nuestro loft de 3 recámaras y 150 m2, en el corazón del Casco Antiguo. Con pisos de madera que irradian calidez y una cocina moderna de diseño abierto ideal para compartir, este espacio garantiza unas vacaciones memorables. Situado en la Avenida A, te encontrarás a solo unos pasos de exquisitos restaurantes, museos, iglesias coloniales y los codiciados rooftops del Casco, convirtiendo cada día en una aventura.

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Guest favorite

Apartment in Panama City

4.97 out of 5 average rating, 94 reviews

Ocean View | Rooftop Pool | Luxury Stay

Wake up to a stunning ocean view right from your window at BrisaMarina. This luxury apartment is located in the spectacular The Sands building, right on the Cinta Costera. The modern and cozy space features bright natural light, air conditioning, high-speed Wi-Fi, and a fully equipped kitchen for your comfort. You’ll be just minutes away from restaurants, beaches, and top attractions. Perfect for couples, business travelers, or weekend getaways.

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Top guest favorite

A private pool area is framed by lush tropical plants and trees, with lounge chairs situated nearby. The pool’s clear blue water reflects the surrounding greenery and the structure in the background, which includes a covered patio for relaxation.

Home in Distrito Arraijan

4.98 out of 5 average rating, 234 reviews

Tropical Haven with Pickleball/Yoga Platform

Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

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Guest favorite

Apartment in Panama City

4.92 out of 5 average rating, 63 reviews

Balboa Avenue Sky Suites

Moderno Apartamento con Vistas Espectaculares en Balboa Avenue | 2 Habitaciones, 2 Baños Bienvenido a tu hogar en el corazón de la ciudad, donde lujo, comodidad y vistas impresionantes se combinan para ofrecerte una experiencia única. Este elegante apartamento de 2 habitaciones y 2 baños está situado en el exclusivo PH The Sands Apartments & Mall en Avenida Balboa, uno de los destinos más codiciados de Panamá.

ValueFamilySleep quality

Superhost

An interior view showcases a modern, multi-level loft with a wooden staircase leading to the upper loft area. Soft lighting creates ambient hues throughout the open space, highlighting the kitchen and living areas, where stylish furniture is arranged for comfort. Exposed stone walls add texture.

Loft in Panama City

4.89 out of 5 average rating, 358 reviews

2B Loft Studio | Design By Paradox

Private 40 m² loft studio in Santa Ana, about a 5-minute walk from Casco Viejo. Loft Studio sleeps up to 3 guests with a Queen bed on a mezzanine and a sofa bed, plus a full kitchen, private bathroom, air conditioning, hot water, fast WiFi, dining space, and a 1.8 m desk. Enjoy a TV with Roku and host-provided Netflix, Disney+, Max, and Prime. Guests have access to the shared balcony, patio, and paid laundry.

ValueLocationLong stay

Guest favorite

Home in Gamboa

4.86 out of 5 average rating, 111 reviews

BirdHouse — Gamboa, Panama Canal Rainforest

BirdHouse: Let's inhabit the space. Designed for people who want to experience the tropics, not shut them out. Open the screens, feel the breeze, listen to the rain, cool off in the pool, and wake to birds and howler monkeys. Located in historic Gamboa, BirdHouse is a place to slow down and experience one of the world’s richest tropical forests from the comfort of a thoughtfully designed home.

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Guest favorite

Apartment in Panama City

4.84 out of 5 average rating, 32 reviews

Cinta Costera Ocean View Suite

Impresionantes vistas al mar y al Casco Antiguo, con acceso directo al complejo turístico Poin Panamá, como una variedad ofertas gastronómicas y bares, para una experiencia vacacional sin igual. ⚠️ Aviso importante: La piscina y el gimnasio del edificio estarán temporalmente cerrados por trabajos de mantenimiento del 24 de agosto al 15 de septiembre de 2026. Agradecemos su comprensión.

FamilyLocationHospitality

Guest favorite