
Guesthouse vacation rentals in Ohio River
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Ohio River
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Retreat to a Boho Chic Guesthouse in a Leafy Family Suburb
Get comfy swaying in the macrame hammock in a living room with a Moroccan vibe. Make breakfast in the bright kitchen and snuggle up on a cozy banquette. This guest house shares a driveway with our home, but it is completely detached and private. The bedroom sleeps two on a queen mattress, and we provide a queen sized inflatable mattress that fits easily in the living room. The property has a stocked kitchen, a washer and dryer, a lovely new bathroom, a two-car garage, and loads of aesthetic.

Cottage Retreat - Wine, Horses, Convenient
Just south of Lexington KY. Cottage Retreat - nestled between horse farms & open land this 25 acre farm is a unique & convenient location to relax and spend time unwinding. 7.8 miles from the Bluegrass Airport, 10.8 miles from Rupp Arena, 8.4 miles from Keeneland - you're close to numerous items of interest. Enjoy the fully remodeled private cottage, stroll down the lane, enjoy the close proximity of horses, and perhaps buy a bottle of wine on site. No pets and no smoking. Thank you.

Mimi's Country Cottage
Quaint, quiet and cozy cottage set in a tranquil park like setting with all the amenities of home. Ten minutes to Shades State Park and twenty minutes to Turkey Run State Park. A great place to stay for the Covered Bridge Festival. 15 minutes to Wabash College, 25 minutes to DePauw University, 45 minutes to Purdue. We live on site and our back door is approximately 600 ft. from from the Airbnb. At this time we do not allow pets. We clean the cottage in accordance with CDC guidelines.

Waterfront Cabin | Peaceful Pondside Escape
Seeking an escape for some peace and quiet? Welcome to The Little Cabin retreat, located on our 50-acre family farm in Ross, Ohio! Let us take you away from the distractions of life to a place where you can soak up nature in a cozy cabin, all within 30 minutes of downtown Cincinnati. You may fish in the lake if you'd like, or take a ride in the paddle boat, or simply enjoy sitting on the porch listening to the birds. Chances are, you may spot wild turkey or whitetail deer scampering by.

Little Cabin in the Woods - Bent not Broken
Discover your next FAVORITE place to visit. Welcome to Always Ranch LLC where this unique, tiny cabin offers you a tranquil spot to relax and unwind. You will be surrounded by nature as we live on a horse ranch. The cabin may look crooked, but the inside it is rustic and warming. See our Guide Book for close by suggestions. We aren't too far away from local attractions. The kitchenette includes mini fridge, microwave, double hot plate and, grill on the outdoor firepit or grill.

The Fountain Square Flat - *No Cleaning Fee*
Step into your private guesthouse retreat in the heart of Fountain Square. This newly built, mid-century modern carriage house offers comfort, style, and total privacy. Enjoy fast Wi-Fi, self check-in, and free private parking— just over 1 mile from Lucas Oil Stadium and Gainbridge Fieldhouse and a short walk to restaurants, bars, and live music. Perfect for couples, solo travelers, or remote workers looking for a sleek, walkable stay in one of Indy’s most vibrant neighborhoods.

Cottage of Eden. Bourbon Trail Stay in Shelby Co.
Listen to the birds sing as the walkway guides you to your quaint cottage getaway. Take in nature, as you’re surrounded by trees, near our sweet chicken coop and a creek that flows down from the deck - all while only 10min from town. Special touches were added of Kentucky Derby photos, books, kitchenware, Bourbon Trail glasses and bourbon barrel heads with local distilleries. The dining table top is even made of wood from Shelby County’s own Bulleit Distilling Company.

Hideaway Hollow
This is a fully furnished picturesque Amish-built cabin in beautiful and secluded Parke County, Indiana. The cabin comes complete with all amenities including full bath with shower, queen bed, A/C, dish TV, wifi internet and full kitchen. There is a large deck attached with a beautiful view of the swinging bridge and the woods. Cook out on the deck's gas grill and enjoy cool evenings by the fire pit (wood provided). Enjoy a nap in the shade in the hammock.

Holtz Häusle | Cozy Apartment in the Woods
You’d never guess this home, tucked back in the woods, was right off of High Street! Find peace and quiet while being only minutes from the fun of Columbus! Hidden away in the Clintonville neighborhood, it’s just a 10 min drive to Downtown. Guests enjoy private access to the entire first floor of this gorgeous house set back in the woods overlooking Adena Brook ravine. Enjoy a luxury apartment experience while relaxing in the solace of the forest around you.

The Carriage House in the Heart of Uptown
The Carriage House in the Heart of Uptown Centerville!! Historic Charm with Modern Comfort. Built in 1897 and fully renovated in 2017, making it one of Centerville’s true hidden gems. Just steps from local restaurants, coffee shops and a scoop (or two) of Graeter’s Ice Cream. It’s perfectly located for your stay. Whether you’re planning a romantic weekend, visiting family, or simply looking to relax, this cozy retreat is the ideal place to unwind.

Elegant Modern Rustic Retreat w/ Hot Tub
A steel framed industrial warehouse converted into an upscale two bedroom rustic-chic living space located within 8 miles of beautiful Lake Cumberland and within 5 minutes of Downtown, Somerset. The city is yours to explore from your own private 2 bed, 1 bath modern rustic retreat. Picture comfy beds, full bathroom, a kitchen built for entertaining, all under a metal tin roof for those rainy days when you just want to curl up and relax.

The Lodge at Three Pines
This one bedroom, one bathroom lodge is a great place to hang out! Conveniently situated on one floor, the space includes a full kitchen with an open plan living and dining area, as well as a games area. This listing can be rented along with "Three Pines Historic Log Cabin," which is located next door, to provide an expanded hang out space and additional bedroom for larger groups. It can also be rented on its own.
Popular amenities for Ohio River guesthouse rentals
Family-friendly guest house rentals

Appalachian Mountain Log Cabin (Private Retreat)

College Cottage

Ruby's Rest

Blanchester Guest Cottage

Mel’s country cottage. Country life near the city.

The Guest House. Cozy 2nd Story Suite

Garden Studio Guesthouse

Cozy Cabin in the Mountains
Guest house rentals with a patio

The Palomino - Centrally Located Loft Apartment

Rural Getaway

Studio apartment above Garage in downtown Madison

NEW Oregon District Cozy Downtown Towhome

Country Escape

A new cabin in the woods, 2 miles from OU!

Entire Guesthouse 2 minutes from I-64

*BRAND NEW* Gem of Germantown Private Derby Suite
Guest house rentals with a washer and dryer

New! Modern and cozy flat! 2 min drive from town!

*Comfy Getaway 2nd floor Apartment

Boaz Brook Farm Guest House

Bright & Cozy 1BR in Charming Mt Adams + Parking

Comfortable Studio In Springboro

Wishing Well Guesthouse On The Lake

Short North Carriage House next to Goodale Park

Perfect Downtown Carriage House - Walkable!
Destinations to explore
- Rentals with an accessible height bed Ohio River
- Cottage rentals Ohio River
- Hotel rooms Ohio River
- Bed and breakfasts Ohio River
- Loft rentals Ohio River
- Rentals with pools Ohio River
- Rentals with breakfast Ohio River
- Boutique hotels Ohio River
- Condo rentals Ohio River
- Rentals with lake access Ohio River
- Serviced apartment rentals Ohio River
- Rentals with outdoor seating Ohio River
- Tiny house rentals Ohio River
- Smoking-friendly rentals Ohio River
- Chalet rentals Ohio River
- Rentals with a home theater Ohio River
- Nature eco lodge rentals Ohio River
- Rentals with beach access Ohio River
- Family-friendly rentals Ohio River
- Train rentals Ohio River
- Rentals with an EV charger Ohio River
- Waterfront rentals Ohio River
- Aparthotel rentals Ohio River
- Rentals with a fire pit Ohio River
- Treehouse rentals Ohio River
- Yurt rentals Ohio River
- Campsite rentals Ohio River
- Houseboat rentals Ohio River
- Ski-in/ski-out rentals Ohio River
- Apartment rentals Ohio River
- Rentals with a washer and dryer Ohio River
- Fitness-friendly rentals Ohio River
- Townhouse rentals Ohio River
- Ranch rentals Ohio River
- House rentals Ohio River
- RV rentals Ohio River
- Farmstay rentals Ohio River
- Rentals with a sauna Ohio River
- Villa rentals Ohio River
- Pet-friendly rentals Ohio River
- Barn rentals Ohio River
- Rentals with a kayak Ohio River
- Dome rentals Ohio River
- Rentals with an accessible height toilet Ohio River
- Beachfront rentals Ohio River
- Cabin rentals Ohio River
- Shipping container rentals Ohio River
- Vacation home rentals Ohio River
- Rentals with a patio Ohio River
- Rentals with a fireplace Ohio River
- Tent rentals Ohio River
- Earth house rentals Ohio River
- Private suite rentals Ohio River
- Rentals with a hot tub Ohio River
- Guesthouse rentals United States
- Things to do Ohio River
- Art and culture Ohio River
- Nature and outdoors Ohio River
- Food and drink Ohio River
- Things to do United States
- Food and drink United States
- Nature and outdoors United States
- Art and culture United States
- Tours United States
- Wellness United States
- Entertainment United States
- Sightseeing United States
- Sports activities United States





