Guesthouse vacation rentals in Ohio River

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Ohio River

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

1 of 1 pages1 / 1
Guest favorite
A living room is furnished with a brown leather couch adorned with neutral-toned decorative pillows and a large area rug. A macrame hammock is suspended nearby, and various plants are placed around the space. A wooden coffee table sits at the center, accompanied by a decorative bowl.
Guesthouse in Loveland
4.97 out of 5 average rating, 630 reviews

Retreat to a Boho Chic Guesthouse in a Leafy Family Suburb

Get comfy swaying in the macrame hammock in a living room with a Moroccan vibe. Make breakfast in the bright kitchen and snuggle up on a cozy banquette. This guest house shares a driveway with our home, but it is completely detached and private. The bedroom sleeps two on a queen mattress, and we provide a queen sized inflatable mattress that fits easily in the living room. The property has a stocked kitchen, a washer and dryer, a lovely new bathroom, a two-car garage, and loads of aesthetic.

Top guest favorite
A cozy sitting area is highlighted by two comfortable armchairs and a stylish coffee table. The fireplace with a tiled surround serves as a focal point, while wall-mounted lamps provide soft lighting. Decorative artwork lines the walls, contributing to the inviting ambiance.
Guesthouse in Columbus
4.97 out of 5 average rating, 324 reviews

Garden Manor Guest House Air BnB

1st floor 1 BR, 1 bath PRIVATE detached Guest House (NOT shared) completely furnished, with kitchen & luxurious king-sized bedroom. Fence enclosed off street parking. Hosts live next door & work from home. In historic Olde Towne East. The area is urban so please expect to see and hear the sights and sounds of City living! About 1 mi to downtown and the Convention Center, 1 mi to Franklin Park Conservatory, 5 mi to The Ohio State University or John Glenn Intn'l Airport (about 11 mins by car).

Top guest favorite
A charming red barn-style guesthouse is shown among lush greenery, with wooden seating in the foreground. Seasonal decorations enhance the welcoming entrance, while a porch is visible, inviting relaxation. Tall grasses frame the scene, contributing to the peaceful atmosphere of the property.
Guesthouse in Maineville
4.95 out of 5 average rating, 273 reviews

The Barn at Serenity Acre

Take it easy at this unique and tranquil getaway, where relaxation abounds. We are located in Warren county, the playground of Ohio. - total and complete renovation in 2021 - fully equipped kitchen - cozy bedroom / living room - spacious bathroom with claw foot tub to soak or shower in, vanity, and robes - walking trails in woods behind our property, access to pool (seasonal), close to restaurants, stores, vineyard, historic towns, very close to Kings Island, bike trails, and so much more

Top guest favorite
Guesthouse in Lebanon
4.95 out of 5 average rating, 494 reviews

Private carriage house on 3 acres!

New for 2024/2025... updated furniture with memory foam sleeper sofa, memory foam king and queen beds, additional twin mattress for floor for extra sleeping options. Outdoor conversation area! Bright and airy carriage house, located behind main house on 3 acres in Lebanon, Ohio. Close to downtown Lebanon, Springboro, Waynesville and short drive to Kings Island. -Kings Island 11 miles -Warren County Sports Park 7 miles -Roberts Center Wilmington 20 miles -Caesar Creek State Park 10 miles

Guest favorite
The living area features wooden walls and a stone fireplace, complemented by soft-glow electronic candles. A cozy armchair is positioned near a window, while a round, textured coffee table sits at the center, adorned with a vase of dried flowers.
Guesthouse in Hamilton
4.98 out of 5 average rating, 254 reviews

Waterfront Cabin | Peaceful Pondside Escape

Seeking an escape for some peace and quiet? Welcome to The Little Cabin retreat, located on our 50-acre family farm in Ross, Ohio! Let us take you away from the distractions of life to a place where you can soak up nature in a cozy cabin, all within 30 minutes of downtown Cincinnati. You may fish in the lake if you'd like, or take a ride in the paddle boat, or simply enjoy sitting on the porch listening to the birds. Chances are, you may spot wild turkey or whitetail deer scampering by.

Top guest favorite
Guesthouse in Hardinsburg
4.96 out of 5 average rating, 351 reviews

Little Cabin in the Woods - Bent not Broken

Discover your next FAVORITE place to visit. Welcome to Always Ranch LLC where this unique, tiny cabin offers you a tranquil spot to relax and unwind. You will be surrounded by nature as we live on a horse ranch. The cabin may look crooked, but the inside it is rustic and warming. See our Guide Book for close by suggestions. We aren't too far away from local attractions. The kitchenette includes mini fridge, microwave, double hot plate and, grill on the outdoor firepit or grill.

Top guest favorite
A modern living area features a cozy sectional sofa, complemented by a sleek coffee table and decorative plants. A wall-mounted television is positioned above a linear fireplace. A green accent wall creates a vibrant backdrop, while framed artwork adds visual interest to the space.
Guesthouse in Indianapolis
4.97 out of 5 average rating, 184 reviews

The Fountain Square Flat - *No Cleaning Fee*

Step into your private guesthouse retreat in the heart of Fountain Square. This newly built, mid-century modern carriage house offers comfort, style, and total privacy. Enjoy fast Wi-Fi, self check-in, and free private parking— just over 1 mile from Lucas Oil Stadium and Gainbridge Fieldhouse and a short walk to restaurants, bars, and live music. Perfect for couples, solo travelers, or remote workers looking for a sleek, walkable stay in one of Indy’s most vibrant neighborhoods.

Top guest favorite
A comfortable living area features a neutral-colored sofa and a wooden coffee table. A ceiling fan hangs above, while a television is mounted on the wall above a decorative fireplace. Natural light enters through two windows, complemented by rustic wall accents.
Guesthouse in Shelbyville
4.98 out of 5 average rating, 134 reviews

Cottage of Eden. Bourbon Trail Stay in Shelby Co.

Listen to the birds sing as the walkway guides you to your quaint cottage getaway. Take in nature, as you’re surrounded by trees, near our sweet chicken coop and a creek that flows down from the deck - all while only 10min from town. Special touches were added of Kentucky Derby photos, books, kitchenware, Bourbon Trail glasses and bourbon barrel heads with local distilleries. The dining table top is even made of wood from Shelby County’s own Bulleit Distilling Company.

Top guest favorite
The exterior of a wooden cabin is presented, showcasing natural logs with a rich brown hue. Flower beds filled with various plants and blooms line the base of the cabin. A white front door is framed by greenery, with steps leading up to the entrance.
Guesthouse in Rockville
4.96 out of 5 average rating, 245 reviews

Hideaway Hollow

This is a fully furnished picturesque Amish-built cabin in beautiful and secluded Parke County, Indiana. The cabin comes complete with all amenities including full bath with shower, queen bed, A/C, dish TV, wifi internet and full kitchen. There is a large deck attached with a beautiful view of the swinging bridge and the woods. Cook out on the deck's gas grill and enjoy cool evenings by the fire pit (wood provided). Enjoy a nap in the shade in the hammock.

Top guest favorite
A rustic cabin is nestled among trees with autumn foliage. A wooden deck leads to the entrance, while a circular trampoline is positioned nearby. Fallen leaves cover the ground, creating a natural carpet that blends with the surrounding forest.
Guesthouse in Columbus
4.95 out of 5 average rating, 134 reviews

Holtz Häusle | Cozy Apartment in the Woods

You’d never guess this home, tucked back in the woods, was right off of High Street! Find peace and quiet while being only minutes from the fun of Columbus! Hidden away in the Clintonville neighborhood, it’s just a 10 min drive to Downtown. Guests enjoy private access to the entire first floor of this gorgeous house set back in the woods overlooking Adena Brook ravine. Enjoy a luxury apartment experience while relaxing in the solace of the forest around you.

Top guest favorite
An inviting living area features a large brown leather sofa, a patterned area rug, and a decorative coffee table atop wide plank wood floors. A cozy corner chair and a lamp add warmth, while the back wall showcases a mural with 'Centerville Carriage.'
Guesthouse in Centerville
5 out of 5 average rating, 273 reviews

The Carriage House in the Heart of Uptown

The Carriage House in the Heart of Uptown Centerville!! Historic Charm with Modern Comfort. Built in 1897 and fully renovated in 2017, making it one of Centerville’s true hidden gems. Just steps from local restaurants, coffee shops and a scoop (or two) of Graeter’s Ice Cream. It’s perfectly located for your stay. Whether you’re planning a romantic weekend, visiting family, or simply looking to relax, this cozy retreat is the ideal place to unwind.

Top guest favorite
The lodge features a vibrant red and white exterior, complemented by large windows that allow for natural light. A welcoming front porch is adorned with a pair of red chairs, while neatly arranged landscaping enhances the inviting entrance.
Guesthouse in DeMossville
4.97 out of 5 average rating, 103 reviews

The Lodge at Three Pines

This one bedroom, one bathroom lodge is a great place to hang out! Conveniently situated on one floor, the space includes a full kitchen with an open plan living and dining area, as well as a games area. This listing can be rented along with "Three Pines Historic Log Cabin," which is located next door, to provide an expanded hang out space and additional bedroom for larger groups. It can also be rented on its own.

Popular amenities for Ohio River guesthouse rentals

Destinations to explore