Guesthouse vacation rentals in Ohio River

Find and book unique guesthouse rentals on Airbnb

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Popular amenities for Ohio River guesthouse rentals

Family-friendly guest house rentals

Superhost
A cozy studio space features a spacious bed with white linens, complemented by a decorative woven throw. A flat-screen TV is mounted above a charming electric fireplace, while a set of windows allows natural light to brighten the room. A small dresser and hanging hooks provide storage options.
Guesthouse in Portland
4.99 out of 5 average rating, 177 reviews

Howdie's Cottage near Nashville and Bowling Green

MackenzieRating, 5 stars2 weeks ago
My husband and I stayed at the cottage for our 2nd anniversary and loved it!! It’s a 30 minute drive to Nashville, but such a private and relaxing location! Michelle was very responsive and friendly. The air bnb was super clean! Would definitely come back again.
Superhost
The living area is furnished with a comfortable brown pull-out sofa and two chairs. A wooden coffee table sits in front, accompanied by a decorative area rug. Natural light enters through a window, with light curtains enhancing the cozy feel of the space.
Guesthouse in Crawfordsville
4.96 out of 5 average rating, 588 reviews

Mimi's Country Cottage

CristineRating, 5 stars6 days ago
This is my second time at this place because I love it! So cozy and clean! Dave and Teri are such kindhearted people! I feel at home when I stay over. I will be seeing them again!! This is a GEM of a place. Love the sweet kitties all around me! Oh and can’t forget how cool it is that they have like 10 chickens! Super cool spot!
Superhost
The exterior of the studio cottage is seen, featuring white siding and red shutters. A walkway leads to the entrance, bordered by vibrant flower pots. Plants are hanging from the front, and a grill area is visible in the background among greenery.
Guesthouse in New Lebanon
4.97 out of 5 average rating, 204 reviews

Cottage on a working market garden

JerryRating, 5 stars2 days ago
As everyone else says...this place is a keeper! Wonderfully homey and comfortable. The hosts are outstanding. The bonus of fresh eggs and produce from the gardens around you is great. We stayed 5 days and will definitely come back on our next trip to the area.
Superhost
A quaint cottage is surrounded by lush greenery, featuring a metal roof and an inviting garden with colorful flowers. A picnic table sits on a stone pathway leading to the front door, enhancing the outdoor space.
Guesthouse in Damascus
4.96 out of 5 average rating, 1,372 reviews

Ruby's Rest

SabineRating, 5 stars2 weeks ago
My dog and I thoroughly enjoyed our 2 night stay and can’t wait to go back. We spent a lot of time on the enclosed patio which is utterly charming with all the decorations, lights and plants . Bed is super comfortable and I enjoyed looking at the amazing book collection . I had the pleasure of meeting Jeffrey and his wife in person. They have created a true haven for travelers .
Superhost
A spacious home is presented in a scenic outdoor setting, with a charming garden of vibrant flowers in the foreground. The building features a combination of textured stone and siding, framed by a serene sunset sky that enhances the peaceful ambiance.
Guesthouse in Versailles
4.97 out of 5 average rating, 236 reviews

French B&B - Lower Level Apt w/ 2 bedrooms

SteveRating, 5 stars4 days ago
The cottage was fantastic, very big and perfect for a peaceful location out of the city!
Superhost
A cozy sitting area is furnished with two slender armchairs and a small ottoman, placed on a decorative rug. A flat-screen TV is mounted on the wall, and a narrow table holds decorative items. Sliding doors lead into the bedroom, enhancing the open feel.
Guesthouse in Louisville
4.96 out of 5 average rating, 768 reviews

Germantown Carriage House w/garage

DonnaRating, 5 stars3 days ago
Cute and comfortable place. Really liked having the garage to keep the car out of the heat. Several spots to eat or have an adult beverage. Really liked Holy Grale. Highly recommend Karen’s Airbnb. 👍
Superhost
A comfortable living area features a gray sofa adorned with yellow accent pillows. A dark coffee table sits centrally, with a decorative cloche on top. Light curtains frame the window, and a flat-screen TV is mounted above a gas fireplace, enhancing the cozy atmosphere.
Guesthouse in Lancaster
4.99 out of 5 average rating, 206 reviews

Wishing Well Guesthouse On The Lake

DavidRating, 5 stars3 weeks ago
We loved our stay in this beautiful setting. Susan is a very gracious host!
Superhost
A wooden door with multiple panes opens into a cozy sitting area. Outdoor seating is provided by a small table and two chairs on a gravel patio. Natural light filters through the door, highlighting the inviting interior and lush greenery outside.
Guesthouse in Evansville
4.9 out of 5 average rating, 629 reviews

Nest: 1905 Carriage House Apartment

BrandonRating, 5 stars6 days ago
Very cool place would recommend to anyone wanting to try something a little different. Very quaint and felt very comfortable. Host was great and very responsive and accommodating on such short notice. Thanks again for hosting us!

Guest house rentals with a patio

Top guest favorite
The studio guest house features a quaint exterior with white siding and a green metal roof. Large windows with light curtains invite natural light, while a wooden barrel planter adds a touch of greenery beside a stone pathway leading to the entrance.
Guesthouse in Hurricane
4.98 out of 5 average rating, 237 reviews

Mountain Momma Homestead Cottage

SamuelRating, 5 stars1 week ago
Great place. Has everything you need for a short stay and is very clean and organized. Also has coffee and water which is super great and hygiene products. Could use a little more water but definitely a great and homey spot. For any other paranoid guest like me, I took a quick look around to find any hidden cameras and there were none to be spotted!
Top guest favorite
The living area features a genuine leather sofa positioned across from a dark wood entertainment unit. Two upholstered armchairs are situated near arched windows, adorned with floral curtains. The walls are decorated with distinctive Gucci wallpaper, and a light rug complements the hardwood flooring.
Guesthouse in Dayton
4.96 out of 5 average rating, 110 reviews

NEW Oregon District Cozy Downtown Towhome

JhadeRating, 5 stars2 weeks ago
This place was so unique and cozy to stay at and the best part was how Super comfortable that bed was?? It felt like I was floating on cloud nine! Also the walls are insulated enough to where you can’t really hear the train so no worries there. :) there’s some great food places around the area too that are super close called Narco Burger and Yummy Burger I’d recommend. Overall great place and would recommend it.
Top guest favorite
The exterior of the cottage is shown, featuring gray siding and a welcoming brick pathway leading to the front door. Lush greenery and blooming flowers are positioned alongside the entrance, enhancing the cottage's inviting appearance.
Guesthouse in Waynesville
5 out of 5 average rating, 131 reviews

Greystone Cottage in Historic Waynesville

DarlettaRating, 5 stars3 days ago
The cottage was charming and was exactly what we needed for a quiet weekend away. Connie was a wonderful hostess and made us feel welcome. We were conveniently close to the bike trail and hiking and especially enjoyed Fort Ancient.
Top guest favorite
A vibrant red barn stands near a clear pond, surrounded by lush green grass and trees. The structure features white accents on its doors, with a bright blue sky overhead. The serene landscape invites exploration and relaxation by the water's edge.
Guesthouse in Marengo
4.96 out of 5 average rating, 223 reviews

Adorable 1-bedroom guest house on small horse farm

ChristinaRating, 5 stars2 days ago
We had a great stay, and the bed was very comfortable. It was a little bit out of the way of things, but we enjoyed the quiet. Would definitely stay again if we were in the area.
Guest favorite
The exterior of a guesthouse is framed by vibrant autumn foliage. A two-car garage is present, with a staircase leading to the entrance. A black bear-themed decoration sits in front, adding a charming touch to the natural surroundings illuminated by warm sunset light.
Guesthouse in Charleston
4.94 out of 5 average rating, 270 reviews

The Bear BnB - Pet friendly, 5 mins to downtown

KateRating, 5 stars3 days ago
Stayed here for a night with my dog. Such a cute place and very cozy!!
Top guest favorite
A charming brick carriage house is surrounded by lush greenery and trees. The exterior features a steeply pitched roof and a bay window. A spacious driveway leads to the two-car garage, enhancing the serene setting on the property.
Guesthouse in Fort Wayne
5 out of 5 average rating, 134 reviews

Welcome To Pine Cone

RickRating, 5 stars2 weeks ago
I have stayed at Holly's place several times now. When I travel to Ft. Wayne for work, her place has become my go-to. You're not just staying in an Airbnb, it feels like home. This week, Holly was especially proactive about letting me know about some work being done to her own home, and communicated everything, and even gave me a chance to find another place. Not a chance I would do that. I like this place that much. Kudos to Holly for being nothing but an outstanding host!
Top guest favorite
A newly built cabin features a covered porch with wooden railings, providing a shaded area. The facade showcases a blend of light and dark siding under a clear blue sky, with greenery framing the cabin, creating a natural setting.
Guesthouse in Athens
4.98 out of 5 average rating, 364 reviews

A new cabin in the woods, 2 miles from OU!

NoelleRating, 5 stars5 days ago
I’ve stayed here twice now and it’s been lovely both times. Sumit was flexible with my check-in time which was extremely helpful. Everything is super clean and the bed is comfy. It’s a very nice place to stay.
Top guest favorite
The interior of the cabin features log walls and a flat-screen TV mounted on a wall shelf. A small electric fireplace is located below the TV. The entrance door is visible, and a bathroom door is on the left. A window with blinds allows natural light inside.
Guesthouse in Belpre
4.97 out of 5 average rating, 264 reviews

Cozy Cabin in the Mountains

StephanieRating, 5 stars4 days ago
We loved our stay at this cozy little cabin nestled in the Appalachian foothills. With so many thoughtful touches (including homemade cookies!)—it was a perfect perch for exploring Marietta and Parkersburg. Thank you Mike and Donna for a wonderful stay! We look forward to visiting again.

Guest house rentals with a washer and dryer

Top guest favorite
A round dining table features a small vase with white lilies, adding a touch of elegance. Sunlight filters through partially closed blinds, creating a soft and bright ambiance. A patterned chair is visible in the background, complementing the kitchen space.
Guesthouse in Indianapolis
4.96 out of 5 average rating, 360 reviews

Hidden Orchard Guest Cottage

AndyRating, 5 stars1 week ago
I really enjoyed my stay at the cottage. It was peaceful, quiet, had everything I needed and provided a great getaway. Would definitely stay here again.
Top guest favorite
A serene country landscape is displayed, featuring a sunset casting warm hues across a grassy field. A large tree frames the scene, with its leaves gently illuminated by the setting sun. A gravel path meanders through the foreground, leading towards the horizon.
Guesthouse in Petersburgh
5 out of 5 average rating, 323 reviews

Stones Throw Country Inn - includes breakfast!

MaureenRating, 5 stars1 week ago
Loved everything about the Stone Throw in! Spotlessly clean, decorated to perfection, 3 bedrooms with comfy beds, delicious breakfast served every morning! AND less than 5 min from the CREATION MUSEUM! The outside picnic table is an added benefit. The grounds are meticulously mowed, multiple kinds of flowers in bloom! Beautiful sunsets seen to end the day. Our hosts were so kind and answered any questions within minutes. We were blessed to find such a place as theirs. We highly recommend a stay with them.
Top guest favorite
An exterior view of a staircase leading up to a private entrance, featuring dark wooden steps and black railings. The structure is adjacent to a stone wall, with a grassy area and trees in the background. Nearby, an outdoor seating area can be seen.
Guesthouse in Sabina
4.95 out of 5 average rating, 116 reviews

*Comfy Getaway 2nd floor Apartment

NancyRating, 5 stars2 days ago
This was the perfect stop for my brother and I on a tour of family history in Kentucky and Ohio. We were looking for a quiet spot to stay near the Centerville Cemetery to look for ancestors who lived nearby in the 1700-1800s, and this was perfect. Marian was very responsive to messages, but let us have our privacy while there so we could relax. The apartment was clean, quiet, and had everything we needed. There was a special surprise of cheesecake (yum!), granola and milk, plus some granola bars, popcorn and bottles of water. Highly recommended and would stay here again!
Top guest favorite
A modern kitchen is presented with white cabinetry and a black and white patterned tile floor. Natural light enters through a window above the sink, highlighting potted plants. A dining area with a wooden table and shelves is visible in the background.
Guesthouse in Millersburg
5 out of 5 average rating, 217 reviews

New! Modern and cozy flat! 2 min drive from town!

AngelRating, 5 stars1 week ago
I really like this place! This place is really warm and quiet, and also I can get two lovely cookie! I would definitively stay here again if I have free time, and I will highly recommend this housing to anyone visiting the area! Thank you again!
Top guest favorite
A modern living space features a nested table set with a marble surface and gold metal frame. Above, decorative pendant lights hang over a kitchen island with high-backed brown bar stools. The kitchen area showcases stainless steel appliances and light cabinetry.
Guesthouse in Nashville
4.98 out of 5 average rating, 131 reviews

Walkable & Modern w/ King Bed & Private Parking!

AlieciaRating, 5 stars2 days ago
Amazing host and property! Pam was so helpful when my friend and I came to spend some time in Nashville. We had booked the wrong date and she helped us to find a place to stay, as she had some guests for the night already. We ended up staying at her space the next day and it did not disappoint. I highly recommend booking here if you are looking to stay away from the hustle and bustle of downtown Nashville.
Top guest favorite
A living room is furnished with a brown leather couch adorned with neutral-toned decorative pillows and a large area rug. A macrame hammock is suspended nearby, and various plants are placed around the space. A wooden coffee table sits at the center, accompanied by a decorative bowl.
Guesthouse in Loveland
4.97 out of 5 average rating, 578 reviews

Retreat to a Boho Chic Guesthouse in a Leafy Family Suburb

LucindaRating, 5 stars3 weeks ago
Brent was very quick to respond to our questions. The place was clean, very boho chic and well appointed. Comfortable bed (very important to me!) and a beautiful place.
Top guest favorite
A kitchen counter showcases a sleek black coffee maker beside a set of clear glass jars. One jar is filled with ice cubes, while a smaller jar holds sugar. All items rest on a smooth wooden tray, contributing to a functional and organized space.
Guesthouse in Washington Court House
4.98 out of 5 average rating, 263 reviews

The Guest House. Cozy 2nd Story Suite

DavidRating, 5 stars3 days ago
Great place to stay. Family friendly and very clean. Have stayed here several times and always had a great time.
Top guest favorite
Guesthouse in Lebanon
4.95 out of 5 average rating, 426 reviews

Private carriage house on 3 acres!

JoeRating, 5 stars4 weeks ago
The property is peaceful and close to shopping and restaurants. Bed was very comfy and apartment was very clean! The place is pretty close to the owners . but we got lots rest

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