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House vacation rentals in Mission

Find and book unique houses on Airbnb

Top-rated house rentals in Mission

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Top guest favorite
A spacious living area features a sectional sofa with colorful cushions, paired with a matching armchair. A patterned ottoman sits in front of the seating, while natural light floods through large windows. Warm wood beams accent the ceiling, creating a cozy ambiance.
Home in Bernal Heights
4.91 out of 5 average rating, 558 reviews

Stylish Spacious Garden Master Bedroom w/ en Suite

Studio (ground floor garage access) with a private bath, lush private patio. Bernal Hts is a hip village within San Francisco. With a choice of some of the hippest bars, restaurants, and parks Bernal's location has not only the convenience of an urban hub, but it has very easy access to public transport. The studio is always professionally cleaned. Expect down pillows and a down comforter and quality Parachute or Brooklinen bedding. **Entrance to bldg is shared - Entrance to the apt is private.

Top guest favorite
A bright living room features a green sofa and two accent chairs, with a wooden wall serving as a backdrop. A fireplace with a sailing model on the mantelpiece is flanked by modern decor. A large television is mounted on the wall opposite the sofa.
Home in Diamond Heights
4.98 out of 5 average rating, 191 reviews

Recharge in a Modern House on a Quiet Street with a View

Stride across upper level with 27 feet of windows unobstructed views on heated floors and sit by a fireplace with a sailing sloop model on the mantelpiece. A mid-century-modern vibe is contrasted by vibrant art & images of George Washington and Nefertiti. Peer through wall of windows with a telescope at a scenic neighborhood or gaze as far you can see the southern landscape. Private entrance. Separate Host's apartment on ground floor accessed via garage. Base price 4 guests, 5 & 6 extra charge

Guest favorite
An open living area features a grey sectional sofa with a patterned throw and a coffee table. A sleek black TV stand supports an HD television. The modern kitchen, observed in the background, includes stainless steel appliances and a wooden bar with seating, enhancing the space's functionality.
Home in Potrero Hill
4.86 out of 5 average rating, 102 reviews

Spacious, stylish, cozy 1 bedroom in Potrero Hill

Just 15 minutes from downtown SF and the SFO airport, this cozy, spacious 1 bedroom apt is the ultimate way to enjoy San Francisco. In Potrero Hill, the sunniest part of SF, the sidewalk level 1 bedroom has modern furnishings and its own private entrance, living room, kitchen, bedroom and bath. Walking distance to bus lines, it is a peaceful and relaxing getaway from the bustling city. A booklet is provided on recommendations on restaurants, places to visit, activities, and transportation!

Top guest favorite
A light-filled living room features a large sectional sofa and two vintage armchairs facing a decorative fireplace. The space is complemented by a coffee table, with art pieces and framed photos adorning the walls, and large windows allowing natural light.
Home in Inner Sunset
4.96 out of 5 average rating, 340 reviews

Walk to Golden Gate Park from a Radiant Home

Experience the best of classic and contemporary style in our bright and spacious home. Enjoy meals in the gourmet kitchen opening to a light-filled room or step onto the deck for coffee overlooking the garden. The open floor plan connects a formal dining room and living room with beautiful period details. Retire upstairs to the large master bedroom connected to a luxurious bathroom. Two spacious bedrooms offer comfort and privacy overlooking a quiet garden and sharing a second full bathroom.

Guest favorite
A spacious bedroom features a warm-colored bedspread over a queen-size bed, complemented by natural light from glass doors leading to a patio. A decorative rug covers the floor, and a desk with a chair is placed near a window, accentuated by potted plants.
Home in Bernal Heights
4.92 out of 5 average rating, 184 reviews

Private Suite & Entrance. No Shared Space.

Enjoy privacy in a newly renovated San Francisco guest suite. You will have your own entrance, bedroom & bathroom complete with a desk, sofa, & mini-fridge. Think of it like a boutique hotel room but cozier! Located in the sunny North Slope of Bernal Heights. Escape the fog and enjoy nearby parks, restaurants, and markets...many within a 5-minute walk. The Mission District is conveniently within walking distance so a number of highly-rated restaurants and cafes are easily accessible.

Top guest favorite
A bright living area is presented, featuring a spacious sectional sofa paired with a wood coffee table. The modern kitchen is visible in the background, equipped with stainless steel appliances. Vibrant artwork adorns the walls, complementing the open dining space with a wooden table and black chairs.
Home in Potrero Hill
4.96 out of 5 average rating, 102 reviews

Lux Large 2BR, Separate Entry, New Renovation

Welcome to Potrero Hill! We are the sunniest neighborhood in the city and are perfectly located. Our home is 15 min walk to SF General Hospital, UCSF, Mission Bay, SOMA, and the Mission district. You will get an entire bottom floor of the house, fully separated from our home. Home is brand new, built in 2022. While you have total privacy, we are on site in case anything comes up. Parking is easy and we are near the freeways, making it easy to get to Silicon Valley, Marin, or Napa.

Guest favorite
A bright dining area features a wooden table surrounded by black chairs. Large windows and skylights allow natural light to fill the space. Green plants are displayed, and a cozy seating nook with cushions is visible. A sliding door leads to a deck area.
Home in Potrero Hill
4.96 out of 5 average rating, 253 reviews

2br Victorian House with Breathtaking views

Amazing Victorian House on top of Potrero Hill one of the best places in San Francisco to have a magnificent view of the city. Spacious house with terrace and garden. Fast Wifi, parking for free 24/7, smart tvs with fire stick. Very close to downtown, the Mission, Castro, Ferry building, AT&T Giants, Chase Center, general hospital, UCSF, just 15 minutes from the airport. Great restaurants, wineries, parks and the historic Anchor Steam Factory in the neighborhood.

Top guest favorite
The exterior of a Victorian Painted Lady showcases intricate detailing and a well-maintained facade. A white vehicle is parked in the driveway, leading to a staircase adorned with decorative elements that guide the way to the front door. Lush greenery surrounds the entrance.
Home in Duboce Park
4.98 out of 5 average rating, 516 reviews

• Spacious 1 Bed Suite in Painted Lady-Duboce Park

Cozy and comfortable suite in a Victorian Painted Lady! Nicely furnished and equipped apartment in the center of a Historical District. Your spacious flat is comfortable, private, secure and centrally located with access to Muni Metro, Bart, UCSF, USF, Alamo Square, Moscone Center, Hayes Valley, NOPA and the Haight Ashbury. Virtually every cool neighborhood in SF is easy to get to from here! Perfect for romantic getaways, corporate travel, or family vacations.

Top guest favorite
A formal dining room features a long wooden table surrounded by several chairs, with a yellow accent chair included. Large windows provide natural light and showcase views of the surroundings, while built-in cabinetry offers ample storage space. The wood flooring adds to the room's elegant design.
Home in Mission Dolores
4.94 out of 5 average rating, 303 reviews

Stunning Home above Dolores Park w/Sweeping Views

A beautiful, fully remodeled 2-story Edwardian home in San Francisco's historic Liberty Hill. Large decks with panoramic downtown views. Ideally located on Liberty Street, steps away from MUNI and walking distance from Dolores Park, the Mission, Noe Valley, and the Castro. Perfect for a couple or small family. Parties or events not allowed.

Top guest favorite
The exterior of a charming white cottage is framed by a large tree and a wrought iron fence. Steps lead to a welcoming entrance, adorned with potted plants. The house features large windows and detailed architectural elements, enhancing the inviting appearance of this historic home.
Home in Duboce Park
5 out of 5 average rating, 146 reviews

Lovely, Unique Home Near Everything

A Queen Anne cottage built in 1890, it looks small from our quiet, tree-lined street, but it has 3 stories and plenty of room. Each room is cozy and stylish, including a room designed for children. Has all amenities and everything you might need is close by. See below for information about our rigorous cleaning and disinfecting protocol.

Superhost
A charming exterior of a classic home is visible, featuring a welcoming entrance with a dark door and a small patio area. Two white chairs are positioned beside a small table, surrounded by greenery. Bright sunlight illuminates the scene, enhancing the serene atmosphere.
Home in Potrero Hill
4.88 out of 5 average rating, 156 reviews

Renovated Home in the heart of Potrero Hill

Spend your time in a classic San Francisco home in the warm and sunny part of SF. Located in Potrero Hill, our home offers bright rooms and an amazing view of Twin Peaks and the Mission District. The level has been recently renovated including brand new appliances, refinished floors, new furniture and new bed/bedding.

Guest favorite
The inviting living room features a well-lit space with two comfortable seating areas. A wooden table sits beside a lamp, while fresh flowers adorn the table. Large windows allow natural light and views of the garden, and a staircase leads to the entrance.
Home in Haight Ashbury
4.87 out of 5 average rating, 541 reviews

Garden Retreat steps from Haight St

One bedroom sanctuary with a beautiful garden view and cozy fireplace. Comes with it's own entrance just steps from bus lines, train, and all that Haight Street has to offer. Complete privacy with a separate bedroom, bathroom, and breakfast bar. There is a pull-out twin bed in the living room as well.

Popular amenities for Mission house rentals

When is the best time to visit Mission?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$23,021 GYDG$21,556 GYDG$22,184 GYDG$22,184 GYDG$22,394 GYDG$23,231 GYDG$23,440 GYDG$23,649 GYDG$28,881 GYDG$28,881 GYDG$28,254 GYDG$21,975 GYD
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Quick stats about house rentals in Mission

  • Total vacation rentals

    Explore 180 vacation rentals in Mission

  • Verified guest reviews

    Over 9,610 verified reviews to help you choose

  • Family-friendly vacation rentals

    60 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 30 rentals that welcome pets

  • Rentals with dedicated workspaces

    130 properties have a dedicated workspace

  • Wi-Fi availability

    180 of Mission vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mission rentals

  • 4.9 Average rating

    Mission stays are highly rated by guests—averaging 4.9 out of 5!

  • Nearby attractions

    Mission's top spots, include Four Barrel Coffee, Balmy Alley, and 16th Street / Mission Bart Station