Vacation rentals in Mission

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Top-rated vacation rentals in Mission

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A spacious bedroom is illuminated by natural light, featuring a minimalist wooden bed with gray bedding. A large artwork hangs above the bed, while a potted plant and small reading lamp add detail. A desk and chair are positioned nearby, enhancing the workspace.
Guest suite in Mission
5 out of 5 average rating, 219 reviews

Large Light Filled Quiet Artist built 2BR Apt

Large, light filled, quiet, private 2 bedroom apartment/guest suite with split bathroom (toilet and sink in one room, soaking tub/shower and sink in other), kitchenette, and ceilings up to 16'. We have been working on this space for the last 2 years to get the details just right, including hand built furniture and art by local artists. Above the din of the Mission, this apartment is a unique space built in the attic of a large Edwardian house run by artists Laurel Roth Hope and Andy Diaz Hope .

Top guest favorite
A bright living area is highlighted by large windows offering city views. A comfortable chair sits beside a floor lamp, with a decorative plant in a pot adding greenery. A dark chest of drawers contrasts with light walls, and a soft blanket drapes across a nearby sofa.
Condo in San Francisco
4.96 out of 5 average rating, 82 reviews

The Tree House

Welcome to The Tree House! Staying here you will embrace the best of San Francisco: our neighborhoods. Located on the hillside of the Dolores Heights neighborhood, this freshly updated 2 bed 1 bath home features bright and open concept living spaces, privacy, and of course, amazing Castro views. Enjoy your time in San Francisco experiencing privacy within the intersection of Castro, Noe, Mission, and Duboce Neighborhoods! Please note, all host reviews are for my previous listing of this home

Guest favorite
A cozy living area features a gray sofa adorned with a patterned throw blanket and colorful cushions. Two round coffee tables are positioned on a textured rug. The wall displays framed records and art, while a coffee bar is set up against the opposite wall.
Guest suite in Bernal Heights
4.95 out of 5 average rating, 260 reviews

Urban oasis! Deck, city views, entire place

Welcome to San Francisco! Looking for the perfect place to stay while visiting the city? Look no further than this charming and contemporary studio that offers panoramic views of the city's skyline and a glimpse of the iconic GG Bridge from your private deck. Located just a short walk from Mission, you'll be able to explore the city easily. Whether you're in town for business or pleasure, this urban paradise will make you feel right at home. A bonus - easy street parking! Book your stay today!

Guest favorite
A private outdoor space features a large sectional couch surrounded by lush greenery and palm trees. A central coffee table sits on stone flooring, creating an inviting area for relaxation or socializing. Soft lighting is provided by hanging bulbs above.
Guest suite in Mission
4.98 out of 5 average rating, 168 reviews

Urban Oasis in the Mission

Modern suite with separate entrance, luxe bathroom, and private outdoor space – all a short walk to the Mission’s best food, bars, and shops! Room amenities include a mini-fridge, coffee/tea makers, Bose speaker, standing desk + large monitor, 49” TV, and king bed with organic mattress. Bathroom features a large tub, walk-in shower, and high-end towels and linens. The peaceful outdoor space is a lovely setting for afternoon drinks or a bite to eat...a true urban oasis in SF’s best location!

Top guest favorite
A wooden outdoor table is set for two with glasses of wine, overlooking a scenic view of the city and bay. Lush greenery frames the view, while the distant landscape features rooftops and distant hills.
Guest suite in Bernal Heights
4.97 out of 5 average rating, 218 reviews

City Oasis (entire place) with views, deck, washer

Looking to unwind near the cultural and technological heart of SF? Nestled on the north slope of sunny Bernal Hill, this charming suite offers stunning views of the city and Golden Gate Bridge, an outdoor deck, and a rainfall shower with stone flooring. You will enjoy access to a washer, dryer and gym. Like to explore? Hike up the hill for 360-degree views, stroll down to the Mission for world-class dining, or get to the rest of SF and Silicon Valley in minutes (message us for more details!).

Top guest favorite
A comfortable sleeping area features a plush bed with soft linens and a decorative throw, complemented by a colorful accent pillow. A stylish couch sits across from the bed, adorned with throws and cushions, while a wall shelf displays books and decorative items, enhancing the inviting space.
Guesthouse in Potrero Hill
4.98 out of 5 average rating, 121 reviews

Safe, modern & newly renovated – a hidden gem

Welcome to our newly renovated Carriage House in the heart of San Francisco! This charming 2-story retreat offers modern amenities, historic character, a stocked kitchenette, live/work space, and comfortable beds. Located between the Mission and Potrero Hill, you’re close to cafes, shops, and venues. We live on site in the main residence and share the property during guest stays. Whether you’re here for work or leisure, our space provides a private, peaceful escape in a prime location.​

Guest favorite
A clean and modern sleeping area features a wooden headboard with two large white pillows resting on a queen-sized bed. Above, a circular woven wall decoration adds texture and warmth to the minimalist setup.
Apartment in Potrero Hill
4.85 out of 5 average rating, 152 reviews

Stylish & quiet studio apartment in Potrero Hill

*FEATURED IN SUNSET MAGAZINE* Welcome to scenic Potrero Hill! Our studio apt has a private entrance & is perfect for city visitors. It sleeps 2, in 1 brand new queen sized bed with a comfy new Nest organic mattress. Our guest studio apartment is newly renovated with brand new modern furniture, super clean and stylish bathroom, and mini kitchen. It has a hot water kettle, sink, minibar style fridge and plates & utensils. Fresh bed linen and towels on arrival and a stock of coffee & tea

Top guest favorite
A spacious bedroom features a sleek, tufted bed adorned with decorative pillows. Nightstands are positioned on either side, equipped with lamps. A cozy bench is placed at the foot of the bed, with light filtering in through the window dressed in soft shades.
Apartment in San Francisco
4.98 out of 5 average rating, 345 reviews

View of Mission Dolores Church in a garden setting

This studio has gets lots of light in the morning and is peaceful with the view of Mission Dolores Church in the background. It’s about 280 square feet. You can’t beat the location and privacy. You also have direct access to a common shared garden. It’s a perfect place to come home to after working in the city or exploring. The location is the best. You don’t need a car when you stay here. VERY IMPORTANT! Before you book, please read my pet and parking disclosures statement below.

Top guest favorite
A tranquil garden area features lush greenery, with tropical plants surrounding a private hot tub. Soft lighting highlights the space, creating a serene ambiance. A pathway leads to the entrance of the suite, ensuring privacy and easy access for guests.
Guest suite in Mission
4.98 out of 5 average rating, 281 reviews

Mission 1BR/BA Garden Suite Separate Entry

Luxury garden suite with separate entrance in the Inner Mission. The garden suite includes: large bedroom with queen-sized bed, private spa-like bathroom (dual rain shower heads, double vanity, lighted makeup mirror, Toto bidet toilet); private den with Xfinity, Apple TV, hi-speed Wi-Fi, mini-fridge; open space with large table for working or dining. Lots of room to spread out & relax. You will be sharing the garden with me and other folks so please respect it as a quiet space.

Top guest favorite
Guesthouse in San Francisco
5 out of 5 average rating, 48 reviews

Garden Retreat-Prv 1BRGood Neighbors. Great Stays

Escape to this stylish 1BR in Mission Dolores—ideal for remote work or a romantic getaway. Enjoy private access to your own bedroom, bathroom (with sauna), living room, and kitchen. Fast Wi-Fi, cozy interiors, and a magical backyard make it feel like home. Shared washer/dryer included. Walk to Dolores Park, Tartine, and BART. A peaceful retreat in SF’s most iconic neighborhood, perfect for work, love, and summer vibes.

Top guest favorite
Two inviting armchairs sit facing an open entrance, creating a seamless connection to an outdoor patio. Steps lead to a well-maintained yard, lined with greenery and serene decor, providing an ideal space for relaxation and enjoyment.
Guesthouse in Mission
4.94 out of 5 average rating, 35 reviews

Lotus Studio - Secluded Mission Getaway

This newly constructed guest suite is ideally located in the heart of the Mission District. Ideal for walking to local attractions and also well served by public transit. The space is well equipped with fridge, microwave, coffee maker, hot water dispenser etc. The queen bed is comfortable and can be folded away during the day to more room. The whirlpool tub is heated and ideal for relaxation.

Top guest favorite
A modern studio features high ceilings and large windows, allowing natural light to fill the room. Elegant furnishings include a spacious bed and a sofa set with a coffee table. A private patio can be seen through the sliding glass doors, enhancing the living space.
Guest suite in Castro
4.98 out of 5 average rating, 164 reviews

Upscale work-friendly apt walkable to Market St

The apartment is brand new with custom built, high end finishes, furnishings and amenities - 11+ feet ceilings, tall sliding doors that allow natural light, central a/c and heat, with a washer and dryer. In the heart of the Castro District near nightlife, numerous bars, restaurants and transportation.

Popular amenities for Mission vacation rentals

Quick stats about vacation rentals in Mission

  • Total vacation rentals

    Explore 640 vacation rentals in Mission

  • Verified guest reviews

    Over 36,000 verified reviews to help you choose

  • Family-friendly vacation rentals

    220 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 130 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    430 properties have a dedicated workspace

  • Wi-Fi availability

    640 of Mission vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mission rentals

  • 4.8 Average rating

    Mission stays are highly rated by guests—averaging 4.8 out of 5!

  • Nearby attractions

    Mission's top spots, include Four Barrel Coffee, Balmy Alley, and 16th Street / Mission Bart Station