Vacation rentals in Mission

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Top-rated vacation rentals in Mission

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A spacious bedroom is illuminated by natural light, featuring a minimalist wooden bed with gray bedding. A large artwork hangs above the bed, while a potted plant and small reading lamp add detail. A desk and chair are positioned nearby, enhancing the workspace.
Guest suite in Mission
5 out of 5 average rating, 219 reviews

Large Light Filled Quiet Artist built 2BR Apt

Large, light filled, quiet, private 2 bedroom apartment/guest suite with split bathroom (toilet and sink in one room, soaking tub/shower and sink in other), kitchenette, and ceilings up to 16'. We have been working on this space for the last 2 years to get the details just right, including hand built furniture and art by local artists. Above the din of the Mission, this apartment is a unique space built in the attic of a large Edwardian house run by artists Laurel Roth Hope and Andy Diaz Hope .

Guest favorite
A cozy living area features a gray sofa adorned with a patterned throw blanket and colorful cushions. Two round coffee tables are positioned on a textured rug. The wall displays framed records and art, while a coffee bar is set up against the opposite wall.
Guest suite in Bernal Heights
4.95 out of 5 average rating, 260 reviews

Urban oasis! Deck, city views, entire place

Welcome to San Francisco! Looking for the perfect place to stay while visiting the city? Look no further than this charming and contemporary studio that offers panoramic views of the city's skyline and a glimpse of the iconic GG Bridge from your private deck. Located just a short walk from Mission, you'll be able to explore the city easily. Whether you're in town for business or pleasure, this urban paradise will make you feel right at home. A bonus - easy street parking! Book your stay today!

Guest favorite
A private outdoor space features a large sectional couch surrounded by lush greenery and palm trees. A central coffee table sits on stone flooring, creating an inviting area for relaxation or socializing. Soft lighting is provided by hanging bulbs above.
Guest suite in Mission
4.98 out of 5 average rating, 167 reviews

Urban Oasis in the Mission

Modern suite with separate entrance, luxe bathroom, and private outdoor space – all a short walk to the Mission’s best food, bars, and shops! Room amenities include a mini-fridge, coffee/tea makers, Bose speaker, standing desk + large monitor, 49” TV, and king bed with organic mattress. Bathroom features a large tub, walk-in shower, and high-end towels and linens. The peaceful outdoor space is a lovely setting for afternoon drinks or a bite to eat...a true urban oasis in SF’s best location!

Guest favorite
A serene outdoor space is depicted, featuring a stone pathway leading down through lush greenery. Sunlight filters through trees, illuminating various plants and shrubs in the garden, creating a calm and inviting atmosphere.
Apartment in Potrero Hill
4.93 out of 5 average rating, 41 reviews

Cozy 1 Bedroom Flat in Potrero

Cozy 1 Bedroom Flat in Potrero Hill. Full service kitchen with dishwasher, spacious bathroom, and a private patio to relax. Enjoy views of iconic Sutro tower and Twin Peaks while you relax, work (1Gbps Fiber Wifi) or watch Apple TV. Brand new queen mattress and a twin size sofa bed. 15 minutes from SFO, walking distance to Mission and Potrero Hill shops and restaurants, and an easy commute to downtown, East Bay, and the famous Embarcadero make this a perfect base for exploring the city.

Top guest favorite
A modern living area is showcased with a comfortable gray couch and a small black side table. A flat-screen TV is positioned on a light-colored media console. A spacious bed is visible in the background, and warm lighting enhances the neutral color palette throughout the room.
Guest suite in San Francisco
4.99 out of 5 average rating, 208 reviews

Dolores Heights Garden Unit

We offer “your place on a hill” in a very desirable neighborhood. Walk to Castro, Noe Valley, Mission, MUNI Metro and BART. This space offers an efficient European style kitchen with a Smart Oven, 2-burner hot plate, microwave, queen bed, comfortable couch and multi-use table. There is free parking for one car available. Your hosts, John and Jody live upstairs and are available quite often to answer any of your questions but we will respect your privacy. We appreciate a no-shoe policy.

Top guest favorite
A comfortable sleeping area features a plush bed with soft linens and a decorative throw, complemented by a colorful accent pillow. A stylish couch sits across from the bed, adorned with throws and cushions, while a wall shelf displays books and decorative items, enhancing the inviting space.
Guesthouse in Potrero Hill
4.98 out of 5 average rating, 121 reviews

Safe, modern & newly renovated – a hidden gem

Welcome to our newly renovated Carriage House in the heart of San Francisco! This charming 2-story retreat offers modern amenities, historic character, a stocked kitchenette, live/work space, and comfortable beds. Located between the Mission and Potrero Hill, you’re close to cafes, shops, and venues. We live on site in the main residence and share the property during guest stays. Whether you’re here for work or leisure, our space provides a private, peaceful escape in a prime location.​

Superhost
A clean and modern sleeping area features a wooden headboard with two large white pillows resting on a queen-sized bed. Above, a circular woven wall decoration adds texture and warmth to the minimalist setup.
Apartment in Potrero Hill
4.85 out of 5 average rating, 152 reviews

Stylish & quiet studio apartment in Potrero Hill

*FEATURED IN SUNSET MAGAZINE* Welcome to scenic Potrero Hill! Our studio apt has a private entrance & is perfect for city visitors. It sleeps 2, in 1 brand new queen sized bed with a comfy new Nest organic mattress. Our guest studio apartment is newly renovated with brand new modern furniture, super clean and stylish bathroom, and mini kitchen. It has a hot water kettle, sink, minibar style fridge and plates & utensils. Fresh bed linen and towels on arrival and a stock of coffee & tea

Top guest favorite
A tranquil garden area features lush greenery, with tropical plants surrounding a private hot tub. Soft lighting highlights the space, creating a serene ambiance. A pathway leads to the entrance of the suite, ensuring privacy and easy access for guests.
Guest suite in Mission
4.98 out of 5 average rating, 281 reviews

Mission 1BR/BA Garden Suite Separate Entry

Luxury garden suite with separate entrance in the Inner Mission. The garden suite includes: large bedroom with queen-sized bed, private spa-like bathroom (dual rain shower heads, double vanity, lighted makeup mirror, Toto bidet toilet); private den with Xfinity, Apple TV, hi-speed Wi-Fi, mini-fridge; open space with large table for working or dining. Lots of room to spread out & relax. You will be sharing the garden with me and other folks so please respect it as a quiet space.

Top guest favorite
The spacious room features a large bed with a light throw and decorative pillows. A comfortable armchair and a small table are positioned near the sliding glass door that opens to the backyard. Light wood flooring and soft area rugs add warmth to the space.
Guest suite in Bernal Heights
4.95 out of 5 average rating, 448 reviews

Northslope Studio in Bernal Heights with a Zen, Leafy Patio

Wake up to the soothing green view from this remodeled in 2023 studio nestled on a sleepy block in Bernal Heights. A peaceful backyard with a Buddha sculpture and a modernist inspired courtyard sit alongside the bedroom, kitchenette and bathroom. Free street parking (parallel) is available on my block and surrounding streets, not restricted, and typically easily available. Note that the in-law studio shares a common front door and foyer with the main house upstairs.

Top guest favorite
An oversized patio is presented, featuring comfortable seating arrangements and a coffee table. Vibrant plants add color, while Victorian-style homes are visible in the backdrop. An umbrella provides shade, enhancing the outdoor relaxation space.
Guest suite in San Francisco
4.96 out of 5 average rating, 81 reviews

San Francisco Charm

A chic hotel room style experience both centrally-located and private. A one bedroom suite w/ private entrance and bathroom in idyllic Noe Valley. The private suite has an oversized patio facing a row of Victorians - a great spot for morning coffee or evening wine. Indoors, all comfort needs are at your fingertips from Nespresso coffee + frother, mini-fridge, teakettle and a smart tv for movies, to ample closet storage and a shower stall bathroom.

Top guest favorite
Guesthouse in San Francisco
5 out of 5 average rating, 47 reviews

Garden Retreat-Prv 1BRGood Neighbors. Great Stays

Escape to this stylish 1BR in Mission Dolores—ideal for remote work or a romantic getaway. Enjoy private access to your own bedroom, bathroom (with sauna), living room, and kitchen. Fast Wi-Fi, cozy interiors, and a magical backyard make it feel like home. Shared washer/dryer included. Walk to Dolores Park, Tartine, and BART. A peaceful retreat in SF’s most iconic neighborhood, perfect for work, love, and summer vibes.

Top guest favorite
Two inviting armchairs sit facing an open entrance, creating a seamless connection to an outdoor patio. Steps lead to a well-maintained yard, lined with greenery and serene decor, providing an ideal space for relaxation and enjoyment.
Guesthouse in Mission
4.94 out of 5 average rating, 35 reviews

Lotus Studio - Secluded Mission Getaway

This newly constructed guest suite is ideally located in the heart of the Mission District. Ideal for walking to local attractions and also well served by public transit. The space is well equipped with fridge, microwave, coffee maker, hot water dispenser etc. The queen bed is comfortable and can be folded away during the day to more room. The whirlpool tub is heated and ideal for relaxation.

Popular amenities for Mission vacation rentals

Quick stats about vacation rentals in Mission

  • Total vacation rentals

    Explore 640 vacation rentals in Mission

  • Verified guest reviews

    Over 36,000 verified reviews to help you choose

  • Family-friendly vacation rentals

    220 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 130 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    430 properties have a dedicated workspace

  • Wi-Fi availability

    640 of Mission vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mission rentals

  • 4.8 Average rating

    Mission stays are highly rated by guests—averaging 4.8 out of 5!

  • Nearby attractions

    Mission's top spots, include Four Barrel Coffee, Balmy Alley, and 16th Street / Mission Bart Station