Guesthouse vacation rentals in Mission Bay, San Diego
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Top-rated guesthouse rentals in Mission Bay, San Diego
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Mission Bay, San Diego guesthouse rentals
Family-friendly guest house rentals
Guesthouse in San Diego
4.77 out of 5 average rating, 881 reviewscharming, colorful, close to beach
Mar 13 – 20
Guesthouse in San Diego
4.69 out of 5 average rating, 274 reviewsSan Diego Studio perfect for Getaway, Close to All
Nov 15 – 22
Guesthouse in La Jolla
4.77 out of 5 average rating, 601 reviews$100-150 night--Windansea #3
Nov 14 – 21
Guesthouse in San Diego
4.89 out of 5 average rating, 183 reviewsSun-filled cottage w/roofdeck
May 28 – Jun 4
Guesthouse in San Diego
4.97 out of 5 average rating, 251 reviewsThe Coziest Retreat in N. PB
Sep 23 – 30
Guesthouse in San Diego
4.93 out of 5 average rating, 503 reviewsModern Surf Cottage
Feb 28 – Mar 7
Guesthouse in Pacific Beach
4.83 out of 5 average rating, 221 reviewsPacific Beach Cottage Blocks from Beaches/La Jolla
Jan 26 – Feb 2
Guesthouse in Kensington
4.97 out of 5 average rating, 509 reviewsCentral & Serene Secret Garden Guesthouse
Sep 13 – 20
Guest house rentals with a patio
Guesthouse in Mission Hills
5.0 out of 5 average rating, 108 reviewsSantorini-Inspired Cottage #1 w/ Hot Tub + Views
Jan 6 – 13
Guesthouse in San Diego
4.98 out of 5 average rating, 101 reviewsKing Bed, Free Parking, Fast Wi-Fi, Full Kitchen
Nov 30 – Dec 7
Guesthouse in San Diego
4.99 out of 5 average rating, 152 reviewsAdorable cottage in Talmadge
Oct 15 – 22
Guesthouse in La Mesa
4.98 out of 5 average rating, 251 reviewsLa Mesa Suite
Jan 2 – 9
Guesthouse in Lakeside
4.94 out of 5 average rating, 102 reviewsSky Mesa-Adorable Cottage on the Hill
Jan 8 – 15
Guesthouse in San Diego
4.99 out of 5 average rating, 143 reviewsMission Hills-Entire Guest House-Center of it All
Jul 28 – Aug 4
Guesthouse in La Mesa
4.97 out of 5 average rating, 131 reviewsDa Hui Hut-Beachy home/La Mesa’s best view and spa
Sep 23 – 30
Guesthouse in La Mesa
4.97 out of 5 average rating, 119 reviewsSan Diego Newly Built Private Guesthouse (Sleep 5)
Oct 8 – 15
Guest house rentals with a washer and dryer
Guesthouse in San Diego
4.88 out of 5 average rating, 304 reviewsRockaway North - Family Friendly, Garage Parking & Laundry
Oct 16 – 23
Guesthouse in Bay Park
4.97 out of 5 average rating, 330 reviewsPrivate Guesthouse with Bay View Deck
Jul 10 – 17
Guesthouse in Pacific Beach
4.96 out of 5 average rating, 205 reviewsRemodeled Cottage 5 Blocks to the Beach w /AC!
Sep 28 – Oct 5
Guesthouse in San Diego
4.91 out of 5 average rating, 166 reviewsBrand New Cozy Detached Casita w/AC & heat
Sep 22 – 29
Guesthouse in San Diego
4.86 out of 5 average rating, 233 reviewsSea Star Cottage
Jan 2 – 9
Guesthouse in San Diego
4.93 out of 5 average rating, 106 reviewsThe studio apartment in Clairemont - New AC unit
Oct 2 – 9
Guesthouse in Ocean Beach
4.89 out of 5 average rating, 285 reviewsRefurbished Indoor/Outdoor Sanctuary in Ocean Beach
Dec 22 – 29
Guesthouse in North Park
4.98 out of 5 average rating, 185 reviewsNorth Park Garden Retreat Casita
Oct 15 – 22
Quick stats about guesthouse rentals in Mission Bay, San Diego
Total rentals
20 properties
Popular amenities
Kitchen, Wifi, and Pool
Wifi availability
20 properties include access to wifi
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Total number of reviews
2.4K reviews
Nightly prices starting at
G$20,853 GYD before taxes and fees
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