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Family-friendly vacation rentals in Mira Mesa, San Diego

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in Mira Mesa, San Diego

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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An outdoor shaded patio area is featured, with a set of six metal chairs surrounding a rectangular table. A barbecue grill is positioned nearby. Lush greenery and colorful flowers are visible in the background, providing a serene environment for outdoor gatherings.

Apartment in Bay Park

4.85 out of 5 average rating, 217 reviews

Rooftop Deck with Ocean Views in Mission Bay

This wonderful green vacation getaway is powered by its own roof mounted solar system which provides for all the energy demands of the property. This bright and airy studio is completely furnished with and includes mini-split AC and heat, wood floors, and a French door to your own patio area. For cooking we provide a microwave, coffee maker and grinder, toaster oven, full sized fridge, filtered water, dishwasher, and an induction hot plate. The bath has a walk in shower with dual shower heads.

A spacious outdoor patio area features a well-maintained green lawn, framed by lush foliage and colorful plants. The horizon showcases a serene sunset, blending warm hues of orange and purple across the sky, creating a peaceful backdrop for relaxation.

Townhouse in Poway

4.85 out of 5 average rating, 289 reviews

"THE VIEW" - Experience a Beautiful Vacation Home

Welcome to "THE VIEW" - our clean, modern home with a breathtaking view! A short distance from: -Downtown -Beaches -La Jolla/Del Mar -SeaWorld -Zoo/Safari Park -Legoland This home includes: -4 Bedrooms -2.5 Baths -Full kitchen, appliances, and amenities -Living room w/large sectional -Smart TVs -Nest thermostat -BBQ Grill -Furnished Patio -LED lighting, and more! Experience the magic of sunset from the comfort of our patio. Book your stay today and create memories that will last a lifetime!

Top guest favorite

An open studio layout features a spacious bed with a textured yellow blanket, alongside a cozy grey sofa. A dining area with white chairs is positioned near the modern kitchen, which includes stainless steel appliances and a large sink, providing a bright and inviting space.

Guest suite in San Diego

4.96 out of 5 average rating, 371 reviews

Studio w/ backyard near La Jolla & Pacific Beach

*If interested in booking for longer than 28 nights pls send us a request and don’t instant book.* 15min to the beach, this inviting studio is filled w/ amenities & hosted with a 5 star experience. Perfect for couples, small families and business travelers. The vibe is a mashup of European sophistication, West African artifacts & Brazilian charisma. The 5 C’s Studio, hits all your senses - sparkling CLEAN. CENTRAL to all attractions. CLASSY, and CALMING for all. In the heart of CA’s finest city!

Top guest favorite

A spacious bedroom features a large wooden bed with gray bedding and a colorful throw. A flat-screen TV is mounted on the wall, and a study area equipped with a desk and chair is visible. Natural light filters through the window, revealing a private porch outside.

Guest suite in Oak Park

4.99 out of 5 average rating, 489 reviews

Super clean & private studio retreat.

We call our place Casita Pacifica (Peaceful Little House) as this suite is a mellow and relaxing retreat, yet in a San Diego suburb only 10-20 minutes from everything. Sadly, we no longer host peacocks, but our space is decorated in memory of their majestic energy. Our standards are high when we travel, so we created a suite that we'd love to stay in ourselves: stocked with goodies, things to do, recommendations, privacy, comfort & above all - cleanliness. WE FOLLOW CDC CLEANING GUIDELINES.

Top guest favorite

The exterior of a two-story house is displayed, featuring a concrete patio area and large glass doors that open to the backyard. Lush greenery surrounds the space, providing a natural setting, while a shaded lounge area with chairs is visible under a patio umbrella.

Home in Rancho Penasquitos

4.91 out of 5 average rating, 162 reviews

West of Rancho Peñasquitos,easy access to freeway

This house is great for families and groups of friends, workers for their business trips. This 2000sq ft , 2 story house has 4 bedrooms/3 full bathrooms with 1bedrm and full bathroom DOWNSTAIRS. A suburban neighborhood that is also conveniently located for visiting tourist sites. Surrounded by a canyon with walking trails. About 8 miles away from Torrey Pines and Del Mar beaches with a lot of dining at Del Mar Village. Airport is just 20 minutes away. 15 miles from Legoland, San Diego Zoo.

An open-concept living area is highlighted by high ceilings and large windows, offering natural light. A modern kitchen features wood cabinets and a white island, while a dining table with turquoise chairs accommodates several guests. A cozy seating area is visible in the background.

4.97 out of 5 average rating, 839 reviews

The Glass House - A Nature Retreat

Enjoy a unique retreat; 180 degrees of views from inside the home. Nestled at the end of a private road, our place is nearby great hiking and countryside wineries. The Glass House provides a magical space and nature retreat where individuals, couples, families and friends can gather together to re-connect with nature, each other, and themselves. The breathtaking mountain top views, the huge deck, hot tub, fireplace, and the open concept living space is unbeatable for the perfect getaway.

A bright kitchen area features vaulted ceilings and large windows offering views of the surrounding greenery. The space includes modern appliances, a mini island with bar stools, and light-colored cabinetry, creating an open and airy atmosphere.

Guest suite in Santa Fe

4.94 out of 5 average rating, 160 reviews

Private Apartment - Secluded 2 Acre Estate/Orchard

Enjoy our serene and beautiful loft apartment in south Rancho Santa Fe. Quiet and completely private retreat on garden like 2 acre farm estate with orchard. Kid friendly and just minutes from the beach, fair grounds, restaurants, golf, horse riding, hiking, and shopping. This spacious 900 sq ft. getaway includes wifi, 2 smart ROKU TVs, full kitchenette, dining table, King bed, additional two twin XL beds. 7 miles from the beach, 2.5 miles from Trader Joe's and multiple restaurants.

A modern studio suite features a queen bed dressed in crisp linens, complemented by a full-size leather sofa and a wooden coffee table. Light streams through a lace-panel curtain, illuminating vibrant wall art. A mini refrigerator is positioned nearby, adding convenience to the space.

Tiny home in Rancho Penasquitos

4.84 out of 5 average rating, 174 reviews

SUPER! Private Studio w/WD 2 Mins from Freeways!

Entire Private Studio Suite. Brand new up dated entire suite with 1 Queen Bed & 1 bath. Ideal for couples, solo adventurers, and business travelers. Studio is fully equipped with 1 queen bed, full size leather sofa, working desk, kitchenette meant for light food warm, mini size refrigerator, single sink meant for light cup and dish wash, AC, heater. All new furniture, mattress, beddings. All shops, restaurants, cinema, hiking trails within minus drive about 1-5 miles away.

Top guest favorite

A cozy guest suite features a king size bed with a multicolored quilt and matching decorative pillows. A comfortable black couch is positioned beside a low coffee table, with a wall art piece displaying a beach scene above. Natural light streams in through the window.

Guest suite in San Diego

4.91 out of 5 average rating, 287 reviews

Cozy Guest Suite -Private 1 bd/1 bath

This private guest suite is centrally located to all of the wonderful attractions that our beautiful city has to offer. The suite has it's own private entry and is completely separated from the rest of the house. It is fully equipped with a king size bed, a comfortable couch, table, coffee, fridge, microwave, TV, and AC/heat. It has it's own private bathroom with bathtub and shower. If you are traveling with children, we can provide a portable crib, and/or air mattress.

Top guest favorite

A bright living area is viewed from the entrance, featuring a gray sofa, a wooden side table, and a striped area rug. Large sliding glass doors provide a view of a private outdoor space with lounge chairs. Modern decor and ceiling fan contribute to the airy ambiance.

Guesthouse in Encinitas

4.97 out of 5 average rating, 157 reviews

Beach Rock Retreat - Private Encinitas Guesthouse

Enjoy San Diego’s North Coast in this tropical PRIVATE Encinitas guesthouse centrally located from beautiful BEACHES, world-class GOLF courses, upscale shopping, and amazing restaurants. Beach Rock Guesthouse offers plenty of PRIVACY in all directions from its SECOND STORY comfortable living space. At 780 sq. ft., it's quiet and airy with lots of LIGHT and everything you need to relax or work in COMFORT during your stay. Short Term Rental City Permit # RNTL-007659-2018

Natural light fills the airy sleeping area, featuring a spacious queen-size bed and cozy seating. French doors open to a serene view of the tree-filled canyon, while large windows ensure a bright atmosphere. A decorative plant adds a touch of freshness to the inviting space.

Guesthouse in Clairemont Mesa West

4.89 out of 5 average rating, 199 reviews

Serene San Diego Canyon Getaway

Our cozy studio-style guest house perched above a tree-filled canyon is a serene getaway in the center of San Diego, just a few minutes' drive to all local attractions and most of our other institutions (colleges, universities, hospitals). The casita is comfortable for two or a small family, with full kitchen capacity to prepare at-home meals. Our weather here is temperate, but if the weather gets hot, we have a silent mini-split A/C unit to cool the casita as needed.

Top guest favorite

The living room features two light-colored sofas adorned with decorative pillows. A round, tufted ottoman stands in the center, complemented by a side table holding decorative items. Natural light filters through the window, and a staircase is visible in the background.

Townhouse in University City

4.86 out of 5 average rating, 147 reviews

UTC Venetian 3 miles La Jolla Beach UCSD Scripps

Approx 3 miles from the most famous La Jolla beach! Only a mile away from UCSD with bus stop right outside the side gate. One of the nicest and most convenient locations in UTC/La jolla. Located right by the 5 and 805 freeway w/52 nearby! Walking distance to Wholefoods, Chase & Citi bank, CVS, Rubios, Nordstroms Rack, Starbucks, CPK, Trader Joes, Ralphs, Wells Fargo, Ross, Best Buy, AMC movie theater, and many restaurants ALSO Westfield Shopping Mall and so much more!

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Popular amenities for Mira Mesa, San Diego family-friendly rentals

Free parking on premises

Air conditioning

Family-friendly home rentals with a hot tub

A spacious living area is highlighted by a large sectional sofa, accompanied by a glass coffee table. Natural light filters through the window treatments, illuminating the neutral tones and accents from indoor plants. A gas fireplace adds warmth to the inviting space.

Home in Encinitas

4.95 out of 5 average rating, 180 reviews

The Ultimate Family Vacation Home | Hot Tub | A/C

Top guest favorite

The beautifully illuminated pool area features a saltwater pool and hot tub under a starry sky. Lush tropical plants surround the space, enhancing the ambiance. A bottle of champagne and flutes are ready for celebration, while cozy seating is visible in the background.

Guesthouse in Talmadge

4.98 out of 5 average rating, 211 reviews

Lovely Guesthouse in garden setting

Top guest favorite

An aerial view captures the layout of a coastal community, showcasing ocean waves lapping at the sandy shore. A pool and landscaped areas are visible in the foreground, with well-maintained homes lining the streets that lead to the beach.

Townhouse in Leucadia

4.98 out of 5 average rating, 128 reviews

Gorgeous Ocean Views with A/C!

Top guest favorite

A vibrant heated pool is surrounded by minimalistic landscaping, featuring tall cacti and a clean white fence. Soft lounge chairs are positioned nearby for relaxation. The clear water reflects the blue sky, creating a refreshing setting for leisure and enjoyment.

Home in Mission Hills

4.94 out of 5 average rating, 251 reviews

Lionhead - Private Boutique Home

Top guest favorite

A bright living area features a large window with ocean views and light blue skies. A wooden coffee table rests on a patterned rug, surrounded by comfortable seating. A flat-screen TV is located on a white media console, enhancing the room's modern look.

Condo in Pacific Beach

4.96 out of 5 average rating, 171 reviews

Beautifully remodeled 10th floor oceanfront condo

Top guest favorite

A spacious living area features large glass sliding doors that reveal an expansive ocean view with a sunset. Comfortable seating includes a modern gray sectional and two accent chairs, inviting relaxation. The room is illuminated with warm, natural light, enhancing the serene coastal atmosphere.

Condo in Pacific Beach

4.94 out of 5 average rating, 299 reviews

Beach Front Condo - Capri by the Sea - Remodeled

An outdoor dining area is illuminated under soft lighting, featuring a table surrounded by chairs. A hot tub is visible in the corner, with lush greenery framing the space, creating a tranquil atmosphere for relaxation and enjoyment.

Home in Hillcrest

4.93 out of 5 average rating, 246 reviews

Beautiful House in Hillcrest with Tub Parking AC

A cozy living area features large front windows offering a panoramic ocean view. Two comfortable armchairs and a round table complement the space, while wooden beams add rustic charm to the ceiling. Natural light enhances the relaxed atmosphere, inviting guests to enjoy the scenery.

Home in Cardiff

4.9 out of 5 average rating, 102 reviews

Ocean Blue House Great for Families

Family- and pet-friendly home rentals

A peaceful outdoor seating area is presented with a round table and several chairs. Silhouetted palm trees create a backdrop against the gradient sky, transitioning from dark blue to orange. A gentle light source adds warmth to the tranquil setting during twilight.

Guesthouse in La Jolla

4.79 out of 5 average rating, 196 reviews

San Diego Shangri-La

A spacious living area is presented with a light grey sofa adorned with decorative cushions. A wood coffee table sits in front, accompanied by a cozy area rug. An open kitchen area is visible in the background, featuring a mix of cabinetry and colorful backsplash tiles.

Loft in Little Italy

4.86 out of 5 average rating, 755 reviews

Sunny, Open 2 Story Apt Downtown w/ Parking

Top guest favorite

A well-appointed sitting area features patterned seating and decorative tables set on a vibrant area rug. A door opens to an outdoor patio with a small dining table and chairs, allowing for seamless indoor-outdoor access. Walls are adorned with various framed artwork.

Guesthouse in Hillcrest

4.98 out of 5 average rating, 172 reviews

Hidden Casita with Private Deck & Patio

A bright living room features a spacious light-colored sofa adorned with orange accent pillows. A wooden coffee table sits in front, and a mounted TV displays available entertainment options. Large windows draped with yellow curtains allow natural light to fill the room.

Guest suite in Greater North Park

4.96 out of 5 average rating, 358 reviews

Urban Canyon Getaway

Top guest favorite

Home in Pacific Beach

4.98 out of 5 average rating, 294 reviews

Rooftop deck AC 5 min Walk to Beach Bay & Sand

A food prep area is displayed with a white microwave and a glass bowl containing various fruits, including bananas, apples, and citrus. Natural light filters through a nearby window, illuminating the warm-toned tile floor and textured walls.

Tiny home in Cardiff

4.91 out of 5 average rating, 371 reviews

Encinitas Cottage/Lanai-Close2Beach

A well-equipped kitchen features wooden countertops and modern appliances. A dining area is set with a table covered in a light blue cloth, accompanied by two glasses. A piece of art hangs on the wall, adding color to the room, while outdoor seating is visible through the window.

Guesthouse in La Jolla

4.93 out of 5 average rating, 576 reviews

Modern Surf Cottage

Top guest favorite

The exterior of a historic home features a charming Tudor-style architecture with a steep roof and decorative brick chimney. Lush green grass and colorful flowers surround a small tree in the well-maintained front yard, complementing the overall classical design.

Guest suite in Kensington

4.98 out of 5 average rating, 258 reviews

Kensington Classic/Historic Tudor - Fully Licensed

Family-friendly home rentals with a pool

Home in Carlsbad

4.87 out of 5 average rating, 178 reviews

OPEN 8/13-18!Ocean View,Pool/Spa,Pets OK,ByBeach

A spacious living area features large windows allowing natural light to illuminate the room. A comfortable couch is positioned next to a dining table, and a wall-mounted TV provides entertainment. Light-colored walls and natural wood flooring contribute to a bright interior ambiance.

Condo in Carlsbad

4.77 out of 5 average rating, 269 reviews

Relaxing Condo on La Costa

Top guest favorite

A clear pool is surrounded by a concrete deck, featuring a blue inflatable shark floating in the water. Nearby, a metal cart holds beach gear, and two lounge chairs are positioned around the pool area, inviting relaxation under the sun.

Guesthouse in Allied Gardens

4.94 out of 5 average rating, 404 reviews

The BEST NEST Clean, peaceful, private, affordable

Condo in Solana Beach

4.83 out of 5 average rating, 125 reviews

Del Mar Beach Club-AC, pool,jacuzzi,tennis, views!

An inviting swimming pool is surrounded by a spacious deck featuring lounge chairs and umbrellas. Lush greenery and palm trees border the area. A large hot tub is positioned beside the pool, offering a relaxing space under clear blue skies.

Apartment in Carlsbad

4.96 out of 5 average rating, 274 reviews

Luxurious La Costa Condo!

A welcoming sitting room features two wooden chairs with green cushions and a comfortable sofa. In the center, a woven coffee table rests on a floral rug. A soft light is provided by a ceiling fixture, with doors leading to a bedroom visible in the background.

Guest suite in La Mesa

4.9 out of 5 average rating, 183 reviews

Charming Suite in Historic Home

A clear swimming pool reflects the sunlight, surrounded by a tiled patio. Lounge chairs are positioned nearby, and a hammock is hung under the porch, offering a space for relaxation. Lush greenery frames the area, enhancing the serene outdoor setting.

Guest suite in La Mesa

4.93 out of 5 average rating, 189 reviews

Hacienda de las Campanas (Bell Hacienda)

A serene outdoor area is surrounded by lush landscaping, with tall palms and vibrant plants enhancing the scenery. A spacious pool is visible, reflecting sunlight, along with a shaded seating area and a covered lounge near the water's edge.

Guesthouse in Ocean Hills

4.89 out of 5 average rating, 309 reviews

1,000 SF Pool House on a Spacious Quiet Oasis Lot

Quick stats about vacation rentals that are family-friendly in Mira Mesa, San Diego

Total rentals
100 properties
Total number of reviews
4.1K reviews
Pet-friendly rentals
40 properties allow pets
Rentals with a pool
30 properties have a pool
Rentals with dedicated workspaces
70 properties have a dedicated workspace
Wifi availability
100 properties include access to wifi

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