
House vacation rentals in Mira Mesa, San Diego
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Top-rated house rentals in Mira Mesa, San Diego
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Mira Mesa, San Diego house rentals
House rentals with a pool

3 BR Urban Oasis with Pool and Spa in Great Area

Southern California Luxury in Quiet Neighborhood

Fletcher Hills luxury, Sunset View, 4 BR, Pool/Spa

Kids Paradise San Diego - Funhouse

Mountain Top Getaway w/ Pool & Hot tub

Bright and spacious home with views, pool & spa.

Secluded Resort View Home. Salt Water Pool & Spa.

University Heights Oasis Getaway
Weekly house rentals

Home in San Diego

Charming Family 3BR w/ Game Room

Close to Everything San Diego | Firepit + Office!

Urban Oasis - Just Remodeled

Dreamy Spanish Style North Park Home w/ Hot Tub

Outstanding Ocean Oasis ❊ Modern, Family Fun Home

Game Room! Patio, Grill, Backyard, Family-Friendly

Modern Urban Stay: Fire Pit, Cabana & Hot Tub
Private house rentals

Luxe Family-Friendly Escape - Hot Tub & Fire Pit

Shadow House Mt. Helix

Serenity Poolside Villa | Central | Private Pool

Custom Casita in Escondido

Welcome to Casa Cortina!

Charming Guest House in Old Town Poway

Peace in Penasquitos

Traveler's Dream New Modern Farmhouse Getaway
Quick stats about house rentals in Mira Mesa, San Diego
Total rentals
210 properties
Total number of reviews
9.5K reviews
Family-friendly rentals
70 properties are a good fit for families
Pet-friendly rentals
30 properties allow pets
Rentals with a pool
20 properties have a pool
Rentals with dedicated workspaces
140 properties have a dedicated workspace
Destinations to explore
- Private suite rentals Mira Mesa
- Rentals with a hot tub Mira Mesa
- Rentals with pools Mira Mesa
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- Rentals with a fireplace Mira Mesa
- Pet-friendly rentals Mira Mesa
- Rentals with a beach view Mira Mesa
- Rentals with a washer and dryer Mira Mesa
- Apartment rentals Mira Mesa
- Family-friendly rentals Mira Mesa
- Rentals with a fire pit Mira Mesa
- Kid-friendly rentals Mira Mesa
- Fitness-friendly rentals Mira Mesa
- Rentals with outdoor seating Mira Mesa
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- Rosarito Beach
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