Family-friendly vacation rentals in Little Italy, San Diego

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in Little Italy, San Diego

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite

Home in Hillcrest

4.95 out of 5 average rating, 314 reviews

Walk to Balboa Park and Hillcrest from an Immaculate Home

Take a stroll through the park, then unwind with a leisurely dinner under the festoon lights. Classic crown molding, hardwood floors, and pared-back tones of gray and taupe create an air of calm at this elegant haven spread out over 1500 square feet. You will find the space charming & spacious with over 1500 sq. feet. This single level property is the lower level of a historic duplex. Hardwood floors, crown molding, gas fireplace and laundry room. Street parking is usually readily available. This A+ location of Banker's Hill is NOT impacted by air plane noise. Enjoy the entire lower level duplex and use of the back yard with patio set for dining. Please note the upper tenant may also want to use this space so this area could be shared. We would love to greet you but are also fine with allowing you to access with a code on the front door. We live nearby and are happy to make suggestions for dining or things to do. Located near numerous restaurants, and Balboa Park, Hillcrest, the zoo, Downtown, Little Italy, and the Convention Center are all within 10 minutes. Be at the beach in less than 15 minutes. The bus line runs up First Ave for easy access to Downtown and Uptown. Near trolley and train station. We are within 10 minutes to the San Diego International Airport and a quick Uber ride to Downtown, Little Italy. Walk to the heart of Hillcrest, Balboa Park and the Zoo. Be at the beach in less then 15 minutes. Central location near the I-5, I-163 & I-8. Because of the hardwood floors, you will hear the footsteps above. The kitchen is well stocked if your a cook and we have an area where you can set up your laptop. wireless available and 3 smart TV's for your enjoyment. Small market less than 1 block away.

Guest favorite

Guesthouse in Kensington

4.97 out of 5 average rating, 582 reviews

Central & Serene Secret Garden Guesthouse

My cozy & stylish Garden Guesthouse features colorful decor that gives a fun, relaxed vibe. Relax in style inside or outside in my peaceful garden w a cup of coffee, or glass of wine. I love to say a hi to my guests yet your privacy is #1. Reach me via Airbnb app if I can help! Kensington is a central, 1920’s historic neighborhood w shops & great local eateries. Close to downtown, Gaslamp, Zoo, airport, beaches, Balboa Park. Bus stop, & trolley nearby. Reserved off street parking space too!

Top guest favorite

Guesthouse in Greater North Park

4.96 out of 5 average rating, 243 reviews

North Park, San Diego's Best At Your Doorstep

Incomparable location, privacy, quality and unique experiences await the discerning traveler. Walk to dozens of renown restaurants, coffee shops, micro-breweries, bars, art galleries, unique shops, stores and world famous attractions from your exceptional detached studio suite. Come see why Forbes Magazine, Time Magazine, The New York Times, The LA Times and The San Diego Union Tribune recently acclaimed North Park as San Diego's Favorite Neighborhood, The Hippest In The Nation and Smokin' Hot!

Superhost

Guest suite in Golden Hill

4.9 out of 5 average rating, 318 reviews

Studio + Loft! Near ConventionC, Blocks to balboa!

Come enjoy San Diego in this bright and private studio w/ a loft and private entrance. Located in Golden Hill and walkable to several coffee shops, restaurants, bars, etc. Just one mile from downtown, San Diego Zoo, the charming neighborhood of South Park (also full of unique local spots), Balboa Park & more. The room is under 300 square feet plus a loft, kitchenette and has a private patio. It shares a wall to the main house but provides complete privacy as you come and go. It’s a true gem!

Top guest favorite

Guest suite in San Diego

4.99 out of 5 average rating, 485 reviews

Super clean & private studio retreat.

We call our place Casita Pacifica (Peaceful Little House) as this suite is a mellow and relaxing retreat, yet in a San Diego suburb only 10-20 minutes from everything. Sadly, we no longer host peacocks, but our space is decorated in memory of their majestic energy. Our standards are high when we travel, so we created a suite that we'd love to stay in ourselves: stocked with goodies, things to do, recommendations, privacy, comfort & above all - cleanliness. WE FOLLOW CDC CLEANING GUIDELINES.

Top guest favorite

Guesthouse in Sherman Heights

4.96 out of 5 average rating, 534 reviews

Romantic Private Garden Studio Near Downtown

A magical private garden surrounds a tiny studio (240 sq ft) with kitchenette in historic residential district, 10 blocks to East Village and Petco BallPark, near Gaslamp Quarter, and one mile to Convention Center and downtown. Easy access to freeways, very close to Balboa Park, San Diego Zoo, and Coronado Island. Airport and train station less than 15 min. We offer a safe, sweet, and contemplative getaway near the city, with WiFi but no TV. One pet OK only with prior approval. 420 friendly.

Superhost

Townhouse in Downtown

4.82 out of 5 average rating, 759 reviews

BEST LOCATION in all of Little Italy & downtown!

Location, location, location! Can't get any closer to the bustling Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. One of the only houses in all of downtown! This modern luxury home is just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & San Diego Zoo! All the frills: ++ Prime location! 98/100 Walker Score rating ++ High-speed internet, Netflix & smart TV ++ A/C ++ Super Host 5-star service

Guest favorite

Apartment in Downtown

4.8 out of 5 average rating, 514 reviews

Stunning 1 Bedroom Apartment w/ Rooftop & Parking

Welcome to My Beautifully Decorated Apt Located in the Historic Harbor Side Neighborhood Known as Little Italy. Open Floor Plan on the 1st Floor. Stairway up to the Lofted Bedroom. High Ceilings & Loads of Light. Relaxing Roof Deck that overlooks Little Italy. Enjoy Dinner Outside at the Large Outdoor Dining Table, Coffee in the Morning in One of the Lounge Chairs or Cuddle up at Night in the Hammock. Little Italy just named "Best Food Neighborhood in California" 1 Free Onsite Parking Spot

Superhost

Guest suite in Golden Hill

4.91 out of 5 average rating, 437 reviews

Sunlit Studio Hideaway | Walk to Gaslamp & More

Make yourself at home in our cozy studio with private entrance. It’s centrally located next to 3 main interstates and near everything San Diego has to offer. Only a 20 min walk downtown or to Petco park. And an easy 10 min drive to Coronado, Old Town, Balboa Park, Sea World, San Diego Zoo. The Convention Center is also nearby if you are attending a special event or conference. Ocean beach and Mission beach is a quick 12 min drive. Single family home with large master suite at back of house.

Top guest favorite

Loft in South Park

4.95 out of 5 average rating, 295 reviews

A 'Suite' Garage Loft in the Heart of South Park

If you're looking for a 'small-time neighborhood feel' in the midst of a diverse and dynamic city, this is it! Our 'Suite Garage' is located in the eclectic, walkable, and historic neighborhood of South Park, just east of Balboa Park, and 3 miles from downtown San Diego. You're surrounded by a wide variety of local restaurants and shops in our little 'hood' and we aren't far from North Park, Hillcrest, Coronado, the beaches, Mission Bay, the San Diego Zoo, Sea World and other popular spots.

Guest favorite

Loft in Downtown

4.95 out of 5 average rating, 686 reviews

Room A at The Dutra Inn - Little Italy

“There’s a strange and wonderful energy on top of The Dutra. I imagine the ghosts of pirates past making their way up from San Diego Bay, and cosmic cowboys riding in from the Tijuana night. Room A is a meeting place. It’s actually where we first met. When you look up from the street below, you can see the rows of whiskey bottles.* You might even spot Pappy Van Winkle himself winking down at you. But from Room A, you can see so much more—rooftops, skyrises, and ships.

Guest favorite

Apartment in Downtown

4.86 out of 5 average rating, 386 reviews

Entire 2bd - Most Convenient Location of San Diego

Professionally cleaned apartment located in Beautiful Bankers Hill - prestigious neighborhood up the hill from Little Italy, perfectly situated in the epicenter of San Diego! Our spacious 2br/1ba is within such short reach of Little Italy, Balboa Park, Downtown, Waterfront Park, Harbor, Airport, etc! Your private apartment comes equipped with high end appliances, finishes, and breath taking views of the city skyline and San Diego Harbor surrounding the property.