House vacation rentals in James Island
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Top-rated house rentals in James Island
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for James Island house rentals
House rentals with a pool
Home in Folly Beach
4.95 out of 5 average rating, 154 reviewsLuxury Beach Living With Heated Pool
Jan 5 – 12
Home in Charleston
4.87 out of 5 average rating, 206 reviewsCharleston Tranquil Marshside Retreat w/Pool/Spa
Oct 10 – 17
Home in Charleston
4.97 out of 5 average rating, 211 reviews2500SF Downtown 1849 home w/ pool and roof deck!
Mar 18 – 25
Home in Mount Pleasant
4.93 out of 5 average rating, 108 reviewsPleasant Place: Newly Built with Pool: Close to downtown/beach
Dec 10 – 17
Home in Seabrook Island
4.98 out of 5 average rating, 110 reviewsBrand New Island Getaway
Apr 22 – 29
Home in Folly Beach
4.87 out of 5 average rating, 101 reviewsRed Sunset | Sunset View Private Pool
Jan 25 – Feb 1
Home in Mount Pleasant
4.97 out of 5 average rating, 122 reviewsPura Vida, minutes to Beaches, w/a Pool!
Dec 17 – 24
Home in Mount Pleasant
4.94 out of 5 average rating, 207 reviewsCoastal Family Getaway, Heated Pool
Oct 5 – 12
Weekly house rentals
Home in Charleston
4.98 out of 5 average rating, 185 reviewsSpacious Family Home on James Island
Sep 19 – 26
Home in Charleston
4.81 out of 5 average rating, 297 reviewsWaterfront Home 5 minutes From Downtown Charleston
Jul 2 – 9
Home in Charleston
4.84 out of 5 average rating, 107 reviewsSpread out, cozy house with large fenced in yard
Sep 24 – Oct 1
Home in Folly Beach
4.83 out of 5 average rating, 133 reviewsLuxury Beach Front Pet Friendly
Oct 11 – 18
Home in Charleston
4.99 out of 5 average rating, 124 reviewsCharleston Boho Bungalow ✨3 MILES FROM DOWNTOWN✨
Aug 25 – Sep 1
Home in Folly Beach
4.91 out of 5 average rating, 242 reviewsPelican's Porch on Folly Beach-Oceanview
Oct 26 – 31
Home in Charleston
4.95 out of 5 average rating, 106 reviewsCozy Home Away From Home
Sep 12 – 19
Home in Charleston
4.86 out of 5 average rating, 273 reviewsCentral Island Home
Jul 20 – 27
Private house rentals
Home in Charleston
4.8 out of 5 average rating, 415 reviewsCharming 1BD with parking!
Sep 10 – 17
Home in Charleston
4.89 out of 5 average rating, 174 reviewsCharleston Gem with Perfect City + Beach Location!
Jun 23 – 30
Home in Folly Beach
5.0 out of 5 average rating, 116 reviewsChic elevated honeymoon cottage, romantic getaway
Oct 23 – 30
Home in Charleston
4.89 out of 5 average rating, 138 reviewsBeautiful updated 50's bungalow in Avondale
Mar 26 – Apr 2
Home in Charleston
4.94 out of 5 average rating, 342 reviewsModern & Cozy Home in Downtown Charleston
Dec 7 – 14
Home in Charleston
4.92 out of 5 average rating, 13 reviewsQuiet home close to everything
Jul 10 – 17
Home in Charleston
5.0 out of 5 average rating, 24 reviewsCharleston - Minutes to Beach - Private Community
Aug 25 – Sep 1
Home in Charleston
4.97 out of 5 average rating, 69 reviewsCentrally Located Duplex, Downtown, Beach
Jul 22 – 29
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