House vacation rentals in Charleston County

Find and book unique houses on Airbnb

Top-rated house rentals in Charleston County

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Top guest favorite
A ranch-style house is showcased with a light pink exterior. Steps lead up to a front porch with a white railing. Lush greenery and palm trees are positioned on either side, enhancing the house's tropical charm.
Home in Mount Pleasant
4.91 out of 5 average rating, 137 reviews

Mt Pleasant Central location Dog friendly Fenced

Centrally located in Mt. Pleasant. 5 miles to beach, 7 miles to downtown Charleston, 2 miles to Shem Cree, 8.5 miles to Shipyard Park. 3 bedroom ranch style house with coastal decor on one acre of private property. Plenty of parking space, so feel free to bring your boat/camper. Large back deck with outdoor seating, gas grill and a view of beautiful large live oaks. Back yard is fenced in with privacy fence and we are pet friendly! Also own 3 room house next door, if more space is needed.

Guest favorite
Home in Mount Pleasant
4.88 out of 5 average rating, 170 reviews

Pleasant Place New Build + Pool Great for Families

Bring your family & enjoy our brand new 2020 built home minutes to downtown Charleston, only 6 miles from the beach! Pleasant Place is in the BEST location to top restaurants & activities. This lovely 2700sqft 4 BR 3 BA pleasantly sleeps 10 guests and has all the familiar comforts of home with a fenced-in pool oasis, on a quiet street within walking distance to the Ravenel bridge connecting you to the heart of Charleston. Just a few minutes drive to the best beaches. Bring the family, book now!

Guest favorite
The bungalow is framed by well-maintained greenery, featuring a welcoming front porch with a light green door. A gravel pathway leads to the entrance, flanked by manicured shrubs and trees, creating an inviting exterior ambiance.
Home in Mount Pleasant
4.91 out of 5 average rating, 205 reviews

Charleston Oasis with Hot Tub, Mins to Dtwn

This charming bungalow style house is located in Mt. Pleasant central to everything you need on vacation. Enjoy a brand new hot tub in the fully fenced in outdoor patio, which also includes a fire pit , grill and seating area. Minutes from the beach, downtown Charleston, local restaurants and Shem Creek. This home showcases vaulted ceilings, a spacious living area and 3 comfortable bedrooms. The home features WFH capabilities, brand new appliances, a stylishly renovated design + more. New UHD

Top guest favorite
The exterior of a two-story home is shown, featuring light yellow siding and dark green shutters. A well-maintained front yard with manicured shrubs flanks the walkway. An American flag hangs from the front porch, and a driveway leads to a single-car garage.
Home in Mount Pleasant
4.93 out of 5 average rating, 127 reviews

Mount Pleasant oasis near beach with private pool!

Beautifully updated Mount Pleasant home with a pool! The home's perfectly located just a few short miles from the IOP beaches and a stone's throw from great shopping nearby. This house is the perfect spot for a family vacation or just a weekend away with friends as it offers 3 bedrooms (2 with queen beds and 1 with a king bed). You can enjoy a day at the beach (5 mins away), just relax by the pool, or swim laps in the endless pool system with a push of a button. LIC# ST260331 Bus# 20139685

Guest favorite
Home in Mount Pleasant
4.9 out of 5 average rating, 209 reviews

Luxurious Artist Cottage - reduced midweek rates

Enjoy the luxury offered in this beautifully decorated coastal cottage owned by artists. Ten min from downtown and 5 min from the sunrises and sunsets on the Charleston Harbor. Five grocery stores are within 5 minutes including. The Mount Pleasant Waterfront Park is five min by car. Beaches & downtown are 10- 15 minutes away. Other airbnb on property: airbnb.com/h/luxuriousartisthome ST permit ST260124 B license BL-24-019339 Other airbnb on property: airbnb.com/h/luxuriouscoastalcottage

Guest favorite
Home in Mount Pleasant
4.91 out of 5 average rating, 205 reviews

Coastal Farmhouse Comfort

Freshly updated house tucked in a quiet neighborhood 1/2 way b/t Sullivan's Is. & Shem Creek. Covered back patio: 55 in smart tv, comfy chairs, gas fire pit, gas grill, dining table, mounted fans to keep you cool and the bugs away. Beach chairs/towels/umbrella included. Bring your dogs! No cats. Large fenced back yard with doggie bags & a hammock by the banana trees! Open floor plan, fully stocked kitchen and outdoor shower! Mt Pleasant business license # bl-24-012302 str permit ST260297

Top guest favorite
A modern kitchen features a light color palette with a retro green refrigerator, open shelving, and elegant lighting fixtures. Two rattan bar stools are positioned at a white countertop, complemented by fresh flowers and a simple decor arrangement on the nearby side table.
Home in Charleston
5 out of 5 average rating, 159 reviews

Petite Maison- guesthouse, Downtown Charleston

Take it easy at this tranquil and gorgeous getaway located in the quiet and trendy downtown neighborhood of Wagener Terrace. Newly renovated, this stylish guest house is just 2 miles from the center of historic Charleston. Petite Maison is the perfect stay for couples or singles looking to live like a local in this popular downtown neighborhood. Enjoy a quiet walk or bike ride to Hampton Park and some of the best restaurants and bars in the city. Residental STR Permit # OP2023-04086

Top guest favorite
The entrance features a solid wooden door with six panels, bordered by two wall sconces providing warm, ambient lighting. A potted plant adds a touch of greenery, complementing the clean lines of the contemporary home exterior.
Home in Mount Pleasant
5 out of 5 average rating, 277 reviews

Upscale EARL CRT 3-bdrm Old Village/Shem Creek

STR PERMIT #ST250176 BUSINESS LICENSE #20135982 3-bdrm Earl's Court neoclassical upscale home, nestled in the heart of the historic Old Village, offering the charm of low country living. Just a block from Shem Creek bars & restaurants, Old Village shops & eateries, Alhambra Hall, Pitt St Bridge, and a weekly all food Farmer's market, featuring low countries finest! The Arthur Ravenel Bridge, downtown Charleston, Sullivan's Island & IOP beaches are all bike riding distance.

Guest favorite
A serene waterway is flanked by lush greenery and reflected clouds, creating a peaceful natural landscape. The calm waters mirror the sky, with a boat visible in the distance, indicating opportunities for exploration and relaxation.
Home in Johns Island
4.94 out of 5 average rating, 125 reviews

The River Girl, Private Dock, Great Outdoor Spaces

The River Girl is located on Johns Island, a beautiful 20 min drive to downtown Charleston, 20 min to Kiawah, & 20 to Folly Beach. We hope this place provides a comfy spot to rest your head at the end of a fun day exploring. We also want you to take advantage of the slow island life! Go crabbing off the dock and cook your supper! Read a book on the back deck & enjoy the breeze. Light a candle, & take a soak in the tub! Just enjoy yourself. Fully updated!

Guest favorite
A spacious living area is furnished with two white sofas and two armchairs, each adorned with teal cushions. A circular coffee table is centered on a patterned area rug, and artwork hangs on the dark walls. Natural light floods the room through large windows.
Home in Charleston
4.97 out of 5 average rating, 267 reviews

2500SF Downtown 1849 home w/ pool!

The perfect Oasis in the middle of the Peninsula... Come home to this 2,500 SF c.1849 historic property and take a dip in the pool after a long day walking around or relax and have a cocktail on the balcony. Walk out the door and explore Cannonborough-Elliotborough and some of the best restaurants the City has to offer. Off-street parking for 1-2 vehicles is provided, a rarity downtown. We are a legal City licensed short-term rental 2026 OP. 07096.

Top guest favorite
A welcoming cottage exterior is showcased, featuring a pale brick facade and a sloped roof. The front entrance is highlighted by a wooden door, flanked by black shutters. Lush green grass and neatly trimmed shrubs provide a neat and inviting landscaping.
Home in Mount Pleasant
4.99 out of 5 average rating, 134 reviews

Mt Pleasant Cottage-Downtown, Shem Creek & Beaches

Make the most of your visit to Charleston by staying at this fully renovated cottage in the heart of Mount Pleasant! This property offers an open floor plan, deck area, and spacious backyard. Conveniently located just minutes away from Shem Creek, Downtown Charleston, Isle of Palms, Sullivans Island, and a variety of restaurants/shopping! -12 mins to Isle of Palms -13 mins to Sullivans Island -12 mins to Shem Creek -14 mins to Downtown

Guest favorite
Home in Mount Pleasant
4.94 out of 5 average rating, 105 reviews

Hot Tub, Putting Green in the Heart of Mt Pleasant

This thoughtfully renovated 2 bed/ 2.5 bath Mount Pleasant townhouse has a sneaky awesome backyard fit-out with putting green, hot tub, and outdoor shower. Watch the game from the jacuzzi! This location couldn’t be more convenient: Just 5 miles to Sullivan’s Island + bike or walk to Whole Foods, Shem Creek, and tons of Mt. Pleasant restaurants. Isle of Palms is 15 minutes, and 10 minutes to Downtown Charleston.

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