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Vacation rentals in De Soto

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in De Soto

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A spacious leather sectional couch is positioned beneath a vaulted ceiling, complemented by two table lamps emitting soft light. Colorful artwork adorns the wall above, featuring nature-themed designs. The room is accented by a patterned rug, creating a welcoming ambiance.
Home in Merriam
4.95 out of 5 average rating, 207 reviews

~Comfort~Space~Location~PetFriendly~Patio~Grill~

🏡 3 bedroom 3 🛌 1 sectional 🛋 2 bath 🛁 3 📺Roku, Local Channels ✅highways, Ikea, Plaza-15 min, Westport10, airport30. Restaurants, stores and places of entertainment ✅Suitable for families with children. We provide a high chair and a playpen. ✅Both bathrooms are on the main floor ✅No stairs (Laundry in the basement) ✅Two car garage, parking on the driveway and street parking ✅ Fenced Backyard ✅Park, playground, picnic shelter within walking distance ❌Pets must stay off furniture and beds

Top guest favorite
The octagonal cottage is surrounded by a well-manicured lawn and features a stepping stone pathway leading to a patio area. Large windows with shutters offer natural light, and a small air conditioning unit is visible on the side of the structure.
Guesthouse in Eudora
4.9 out of 5 average rating, 235 reviews

Cozy cottage getaway in garden paradise

Get away and relax in a whimsical octagonal cottage surrounded by a lush garden, overlooking a swimming pond and the Wakarusa river. You will have everything you need for a romantic date night or an inspiring place to slow down and reconnect with nature. •1 bedroom open living space with lots of natural light and beautiful views. • Coffee cart with microwave and electric burner and mini frig are provided. • Paddle boat at the lower pond & 2 disc golf nets available for fun. •NO PETS ALLOWED

Guest favorite
A two-story blue farmhouse is seen from the front yard, surrounded by lush green grass and blooming irises. The covered porch invites relaxation, while a clear blue sky provides a bright backdrop. A walkway leads up to the entrance, enhancing the home's welcoming appeal.
Home in De Soto
4.92 out of 5 average rating, 168 reviews

Grandma B’s House: 3BR Near KC Weddings & WC26

Stay in a restored 1920s Victorian farmhouse in walkable downtown De Soto, KS—just 15–20 minutes to Lawrence and KC. Ideal for 💍 weddings, ⚽ FIFA 2026, and family trips. This 3BR/2BA home offers a stocked kitchen with coffee bar, dining for 8, Smart TV, fast WiFi, workspace, and covered porches. Peaceful small-town setting near KC venues: Sporting KC, Azura Amphitheater, Stone Pillar Winery, The Barn at Kill Creek, Panasonic. Steps at both entrances; bedrooms upstairs. Rental agreement req’d.

Guest favorite
Three horses graze on lush green grass under a glowing sunset. The sun casts a warm light across the landscape, creating a serene backdrop. A dog is visible nearby, adding a friendly element to the peaceful countryside scene.
Farm stay in Weston
4.93 out of 5 average rating, 365 reviews

Hippie Hills - Cozy Country Lodging and a Hot Tub

FIFA World Cup Visitors: We speak Dutch, German & Swiss German. Like a storybook, but with Wi-Fi, a hot tub, and a serious hospitality crew. Dogs Taco, Ally, and Bullet greet you at your car, frisbee in tow and zero chill. Donkeys Slim and Shady expect breakfast negotiations, while cats Potato and French Fry judge from afar. Horses Pieces and Jasper love head scratches. Historic Weston, is 5 minutes away with shops, wineries, and charm. After exploring, unwind in the hot tub under starry skies

Top guest favorite
A rustic cabin with a wooden exterior is surrounded by lush greenery. Large windows allow natural light to brighten the interior. A spacious deck is visible in front, with outdoor seating and a grill, offering a welcoming space for relaxation near the lake.
Farm stay in Excelsior Springs
4.96 out of 5 average rating, 315 reviews

San Vincente Lake Cabin at SundanceKC

Our beautiful light filled cabin with wood-burning fireplace is perched above our spring-fed 15 acre private lake next to the common outdoor lounge area and sand beach. We have 200 acres of gorgeous property with limestone boulders and hiking trails throughout. The lake is great for swimming, kayaking, stand-up paddle boarding and offers excellent fishing. We are five minutes from downtown Excelsior Springs, Excelsior Springs golf course and 3EX municipal airport. Relax, rejuvenate and play.

Guest favorite
Loft in River Market
4.81 out of 5 average rating, 196 reviews

Retro Loft Street Car Access RiverMarket

Hop in your time machine... retro vibes are calling your name! Designed with the traveler in mind, the space is stocked with amenities you want. WFH Desk space, fully stocked kitchen, bluetooth speaker, gym, game room, coffee bar, tons of seating & more! Located in the River Market. Walk to shops, restaurants, coffee, bars, plant shops, farmers market & more. Street car access to take you to the T-Mobile Center, Union Station and more. Highway access close by. Game room in the building!

Top guest favorite
Treehouse in Easton
5 out of 5 average rating, 236 reviews

Serenity Creek Treehouse Hidden Valley Retreat

Escape to an adult/teen+ only (12+ yrs) enchanting interconnected treehouse/ tree cabin @ Hidden Valley Wilderness Retreat. Serenity Creek - a private north & south treehouse connected via short open air walkway. - Wing 1: mini-kitchen/light cooking, lvg rm, screened porch, shower rm. + sink vanity. -Wing 2: queen bed, 1/2 bath rm (toilet+ sink.) 2 mi. walking trails, 32+ acres, 2 sm ponds. Main retreat house close by + 2 treehouse/cabins for other guests. Rest in a peaceful setting!

Top guest favorite
A newly renovated log cabin is surrounded by lush greenery, offering a tranquil entrance. A stone pathway leads to the rustic wooden door, while a picnic table is positioned nearby under the shade of a tree, enhancing the inviting outdoor space.
Cabin in Tonganoxie
4.96 out of 5 average rating, 849 reviews

Cozy Cabin Retreat

Escape to our cabin which earned top-rated Airbnb in all of Kansas for a cozy, quiet getaway. Ideal for unwinding and rejuvenating after the demands of a hectic day. Enjoy scenic hiking trails, axe throwing, horseshoes, or a peaceful walk through our labyrinth. End the day with a stunning sunset over the valley from our swing. Just 5 minutes from the lake! Note: The cabin is on a shared property with a retreat center, Sacred Hearts Healing.

Top guest favorite
Guest suite in Kansas City
4.97 out of 5 average rating, 174 reviews

Delightful Patio Retreat w/Pool Table in South KC

Come and enjoy this delightful, newly remodeled space with brand new bathroom. Apartment is the lower level, with It's own private entrance, queen bedroom, full bath w/walk-in shower, full size pool table and 42" TVs in living room & bedroom. The woods border the back yard for extra privacy. A creek, arbor, gazebo & statue. Conveniently located at 435 & Holmes Rd, where you can quickly get anywhere you need to go in the city.

Top guest favorite
A tiny house made of wood stands surrounded by cedar trees, with a wooden deck leading to its entrance. A small table with two chairs is placed nearby, illuminated by hanging lights, providing a serene outdoor seating option.
Tiny home in Perry
4.96 out of 5 average rating, 572 reviews

The Batch - Tiny House Living

Located 20 minutes from downtown Lawrence, the Batch is a sustainable tiny house nestled in the cedar forests of Perry, KS. Decorated in a minimalist southwestern style, this tiny cabin is a serene and peaceful setting for souls seeking restoration, quiet, and the healing qualities of the woods. Or just a great place to getaway with your love or friends with an even greater view!

Guest favorite
A charming outdoor patio is illuminated by string lights, creating a cozy ambiance. A variety of seating options can be seen amidst lush greenery and flower beds, providing a welcoming space for relaxation. The brick exterior of the home contrasts with the warm glow from the lights.
Apartment in Edwardsville
4.91 out of 5 average rating, 133 reviews

Apartment H-Hideaway Cozy Stay among flowers

If you are looking for a quiet stay in a country setting but still minutes away from the city this is your place. Enjoy the eclectic style of this one bedroom suite on the lower level of our home with a private entrance. We offer a full galley kitchen with a few of our favorites for snacking. Our space is nestled on our Hobby Farm. We are minutes from I-435 & I-70.

Top guest favorite
A green sign for Crescent Moon Winery is prominently displayed. The sign features a distinctive logo and offers information about the tasting room hours. A vineyard is visible in the background, with rolling hills and a faint rainbow appearing above the landscape.
Home in Tonganoxie
4.94 out of 5 average rating, 186 reviews

Guesthaus at Crescent Moon Winery

This beautiful country setting is located on a paved road next to a producing vineyard and winery. The views of the countryside and pond are memorable. Enjoy a stroll through the vineyard and watch the grapes grow! If you book during harvest, you are welcome to help pick grapes watch them become wine! Our tasting room is open weekends or by appointment.

Popular amenities for De Soto vacation rentals

  1. Airbnb
  2. United States
  3. Kansas
  4. Johnson County
  5. De Soto