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Vacation rentals in De Soto

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in De Soto

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A spacious leather sectional couch is positioned beneath a vaulted ceiling, complemented by two table lamps emitting soft light. Colorful artwork adorns the wall above, featuring nature-themed designs. The room is accented by a patterned rug, creating a welcoming ambiance.
Home in Merriam
4.95 out of 5 average rating, 207 reviews

~Comfort~Space~Location~PetFriendly~Patio~Grill~

🏡 3 bedroom 3 🛌 1 sectional 🛋 2 bath 🛁 3 📺Roku, Local Channels ✅highways, Ikea, Plaza-15 min, Westport10, airport30. Restaurants, stores and places of entertainment ✅Suitable for families with children. We provide a high chair and a playpen. ✅Both bathrooms are on the main floor ✅No stairs (Laundry in the basement) ✅Two car garage, parking on the driveway and street parking ✅ Fenced Backyard ✅Park, playground, picnic shelter within walking distance ❌Pets must stay off furniture and beds

Top guest favorite
The octagonal cottage is surrounded by a well-manicured lawn and features a stepping stone pathway leading to a patio area. Large windows with shutters offer natural light, and a small air conditioning unit is visible on the side of the structure.
Guesthouse in Eudora
4.9 out of 5 average rating, 235 reviews

Cozy cottage getaway in garden paradise

Get away and relax in a whimsical octagonal cottage surrounded by a lush garden, overlooking a swimming pond and the Wakarusa river. You will have everything you need for a romantic date night or an inspiring place to slow down and reconnect with nature. •1 bedroom open living space with lots of natural light and beautiful views. • Coffee cart with microwave and electric burner and mini frig are provided. • Paddle boat at the lower pond & 2 disc golf nets available for fun. •NO PETS ALLOWED

Guest favorite
A two-story blue farmhouse is seen from the front yard, surrounded by lush green grass and blooming irises. The covered porch invites relaxation, while a clear blue sky provides a bright backdrop. A walkway leads up to the entrance, enhancing the home's welcoming appeal.
Home in De Soto
4.92 out of 5 average rating, 168 reviews

Grandma B’s House: 3BR Near KC Weddings & WC26

Stay in a restored 1920s Victorian farmhouse in walkable downtown De Soto, KS—just 15–20 minutes to Lawrence and KC. Ideal for 💍 weddings, ⚽ FIFA 2026, and family trips. This 3BR/2BA home offers a stocked kitchen with coffee bar, dining for 8, Smart TV, fast WiFi, workspace, and covered porches. Peaceful small-town setting near KC venues: Sporting KC, Azura Amphitheater, Stone Pillar Winery, The Barn at Kill Creek, Panasonic. Steps at both entrances; bedrooms upstairs. Rental agreement req’d.

Top guest favorite
A rustic cabin with a wooden exterior is surrounded by lush greenery. Large windows allow natural light to brighten the interior. A spacious deck is visible in front, with outdoor seating and a grill, offering a welcoming space for relaxation near the lake.
Farm stay in Excelsior Springs
4.96 out of 5 average rating, 315 reviews

San Vincente Lake Cabin and SundanceKC

Our beautiful light filled cabin with wood-burning fireplace is perched above our spring-fed 15 acre private lake next to the common outdoor lounge area and sand beach. We have 200 acres of gorgeous property with limestone boulders and hiking trails throughout. The lake is great for swimming, kayaking, stand-up paddle boarding and offers excellent fishing. We are five minutes from downtown Excelsior Springs, Excelsior Springs golf course and 3EX municipal airport. Relax, rejuvenate and play.

Guest favorite
Loft in River Market
4.81 out of 5 average rating, 196 reviews

Retro Loft Street Car Access RiverMarket

Hop in your time machine... retro vibes are calling your name! Designed with the traveler in mind, the space is stocked with amenities you want. WFH Desk space, fully stocked kitchen, bluetooth speaker, gym, game room, coffee bar, tons of seating & more! Located in the River Market. Walk to shops, restaurants, coffee, bars, plant shops, farmers market & more. Street car access to take you to the T-Mobile Center, Union Station and more. Highway access close by. Game room in the building!

Top guest favorite
Treehouse in Easton
5 out of 5 average rating, 236 reviews

Serenity Creek Treehouse Hidden Valley Retreat

Escape to an adult/teen+ only (12+ yrs) enchanting interconnected treehouse/ tree cabin @ Hidden Valley Wilderness Retreat. Serenity Creek - a private north & south treehouse connected via short open air walkway. - Wing 1: mini-kitchen/light cooking, lvg rm, screened porch, shower rm. + sink vanity. -Wing 2: queen bed, 1/2 bath rm (toilet+ sink.) 2 mi. walking trails, 32+ acres, 2 sm ponds. Main retreat house close by + 2 treehouse/cabins for other guests. Rest in a peaceful setting!

Guest favorite
A spacious reproduction Conestoga wagon is positioned on a gravel surface, with a covered outdoor kitchen nearby. The vibrant sunset paints the sky in warm colors, while the surrounding grassy area offers an open, tranquil setting for relaxation.
Farm stay in LaCygne
4.96 out of 5 average rating, 106 reviews

Covered Wagon1 @IsinglassEstate

Isinglass Estate is anything but ordinary. Our reproduction Conestoga Wagons have it all- with heat, A/C, a full bathroom, your own private outdoor kitchen and firepit, and five star details to complement the 100acre views of the polo field and vineyards! Wagon guests enjoy access to our 600 acre estate with fishing, hiking, vineyards, blackberries, a petting zoo, horseback rides, horse-drawn carriage rides, plus a restaurant and winery tasting room all on-site.

Top guest favorite
A newly renovated log cabin is surrounded by lush greenery, offering a tranquil entrance. A stone pathway leads to the rustic wooden door, while a picnic table is positioned nearby under the shade of a tree, enhancing the inviting outdoor space.
Cabin in Tonganoxie
4.96 out of 5 average rating, 849 reviews

Cozy Cabin Retreat

Escape to our cabin which earned top-rated Airbnb in all of Kansas for a cozy, quiet getaway. Ideal for unwinding and rejuvenating after the demands of a hectic day. Enjoy scenic hiking trails, axe throwing, horseshoes, or a peaceful walk through our labyrinth. End the day with a stunning sunset over the valley from our swing. Just 5 minutes from the lake! Note: The cabin is on a shared property with a retreat center, Sacred Hearts Healing.

Top guest favorite
The living area features a comfortable white sofa facing a large wall-mounted TV, above which an electric fireplace is integrated into a modern media console. Decorative plants and crafted art pieces are arranged throughout the space, enhancing the contemporary design.
Loft in Lawrence
5 out of 5 average rating, 132 reviews

On Mass St • Stylish, Quiet & Super Cozy Stay

Stay right on Mass Street in this spacious 1,400 sq ft open-concept loft designed for comfort, light, and walkable convenience. Despite its central location, the space is calm and comfortable inside, making it easy to relax after a day downtown. Enjoy modern finishes, generous living areas, and quick access to dining, shopping, and KU. Ideal for couples, friends, or families who want space and location without sacrificing comfort.

Top guest favorite
Guest suite in Kansas City
4.97 out of 5 average rating, 174 reviews

Delightful Patio Retreat w/Pool Table in South KC

Come and enjoy this delightful, newly remodeled space with brand new bathroom. Apartment is the lower level, with It's own private entrance, queen bedroom, full bath w/walk-in shower, full size pool table and 42" TVs in living room & bedroom. The woods border the back yard for extra privacy. A creek, arbor, gazebo & statue. Conveniently located at 435 & Holmes Rd, where you can quickly get anywhere you need to go in the city.

Top guest favorite
A tiny house made of wood stands surrounded by cedar trees, with a wooden deck leading to its entrance. A small table with two chairs is placed nearby, illuminated by hanging lights, providing a serene outdoor seating option.
Tiny home in Perry
4.96 out of 5 average rating, 572 reviews

The Batch - Tiny House Living

Located 20 minutes from downtown Lawrence, the Batch is a sustainable tiny house nestled in the cedar forests of Perry, KS. Decorated in a minimalist southwestern style, this tiny cabin is a serene and peaceful setting for souls seeking restoration, quiet, and the healing qualities of the woods. Or just a great place to getaway with your love or friends with an even greater view!

Guest favorite
A charming outdoor patio is illuminated by string lights, creating a cozy ambiance. A variety of seating options can be seen amidst lush greenery and flower beds, providing a welcoming space for relaxation. The brick exterior of the home contrasts with the warm glow from the lights.
Apartment in Edwardsville
4.91 out of 5 average rating, 133 reviews

Apartment H-Hideaway Cozy Stay among flowers

If you are looking for a quiet stay in a country setting but still minutes away from the city this is your place. Enjoy the eclectic style of this one bedroom suite on the lower level of our home with a private entrance. We offer a full galley kitchen with a few of our favorites for snacking. Our space is nestled on our Hobby Farm. We are minutes from I-435 & I-70.

Popular amenities for De Soto vacation rentals

  1. Airbnb
  2. United States
  3. Kansas
  4. Johnson County
  5. De Soto