Vacation rentals in St. Charles

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Top-rated vacation rentals in St. Charles

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Guest favorite
A cozy corner seating area features a bright blue upholstered couch with decorative pillows. A low, circular wooden table is positioned centrally. A green door with a unique design adds character to the wall, while framed artwork and photographs adorn the surrounding space.
Apartment in Clarksdale
4.93 out of 5 average rating, 184 reviews

The Squeeze Box-"get your Blues on"

LOCATION-LOCATION-LOCATION The Squeeze Box is a spacious, airy 425 sq. ft. private vacation apartment, located in the heart of Historic Downtown Clarksdale, Mississippi. The newly constructed apartment is located on the ground floor of the former Clarksdale Telegraph Building (Circa 1897) @ the corner of Second & Delta in the Historic Blues District. Located across the street from the Hambone Art Gallery, and the “Rock & Blues Museum”, this is the best location in town. Gift shops around the corner. Restaurants including The Stone Pony, Yazoo Pass, Levon's Bar and Grill, and Grandma's House of Pancakes are literally all within 300 feet of our front door. CatHead Blues, Lambfish Gallery, and Hambone Gallery are all on our block. The Delta Blues Museum is a short walk, and Ground Zero Blues Club, New Roxy and Red’s Lounge are an easy 5-minute stroll. The Squeeze Box is the best location in Clarksdale for walkable access to restaurants, music venues, museums,bars, clubs,art galleries,shopping on Delta,convenience store,and the wine & spirits store. No need to drive once you check in.....park your car, and party to your heart's content. And The Squeeze Box is located on the ground floor, so there are no stairways to climb or drag your bags up. And we have a covered veranda out front with seating for six,so you can enjoy the fresh air, while enjoying a nice beverage. Although there is no smoking allowed in the apartment, the veranda is just outside your door. Available by the night,weekends, and weekly. Inquire about longer stays.

Guest favorite
A single-story brick house is viewed from the front, featuring a spacious lawn with green grass. A concrete pathway leads to the covered entryway. The garage is visible on the right side, and trees create a natural backdrop in the surrounding area.
Home in Lexa
4.94 out of 5 average rating, 17 reviews

Home away from home!

Looking for a peaceful tranquil setting? This family friendly 3 bedrooms, 2 full baths, sleeps up to 6. Full kitchen & appliances, dishwasher; washer/dryer; central AC/Heat; TV in each bedroom & family area. Front door no step entry. Enjoy the front porch swing and yard area with plenty of parking. Wi-Fi; security lights; home security system for a peaceful stay. 19 minutes to Helena/West Helena King Biscuit Blues Festival, 22 minutes to Isle of Capri Casino in Lula, MS; 12 minutes to Marianna.

Superhost
The great room features a floor-to-ceiling stone fireplace, enhancing the cabin's rustic charm. Dark tile flooring contrasts with the warm wooden walls and ceiling beams. Comfortable seating includes two sofas and an ottoman, with a dining area visible in the background.
Cabin in De Valls Bluff
4.8 out of 5 average rating, 10 reviews

White River Log Cabin w/ Game Room, Outdoor Living

Walking distance to the White River. This true log cabin is 30 min to Stuttgart, Arkansas (Duck Hunting Capital of the World). However, there’s no reason to leave De Valls Bluff! Quick walking distance to public land for hunting - no boat needed. Plenty of parking for boats + trucks if desired. 5 smart TVs for added comfort Cabin formerly used as “Red Oak Duck Camp” owned by world champion duck caller + NFL QB Devlin “Duck” Hodges, who is engaged to Grammy-winning country artist Lainey Wilson

Top guest favorite
The exterior of the building is illuminated by soft lighting at dusk, highlighting a wraparound porch. The structure features multiple entry points and is surrounded by trees, extending into a spacious lawn area.
Farm stay in De Witt
5 out of 5 average rating, 10 reviews

Grandview Acres Lodge

Grandview Acres guests are blessed with a county atmosphere AND city convenience. Located 25 miles south of Stuttgart, just outside DeWitt city limits. 5900 sq.ft. with wraparound porch where you can sit and watch the deer graze. Will accommodate 6-10 guests with all the comforts of home. Large gathering space with satellite tv and ample seating, full gourmet kitchen, dining table for 10, wet bar area, guest half bath, pool and foosball tables, and room to spare for the event you have in mind.

Guest favorite
Houseboat in Dumas
4.91 out of 5 average rating, 35 reviews

River getaway

Vacation getaway nestled on the Arkansas River in the Pendleton community. Fish from the porch or bring your own boat and keep it in the private covered boat slip. The public boat launch is walking distance away. Several fishing tournaments are held every year at this location. The Wilbur D Mills Dam is less than 5 miles downstream, where you can experience world class catfishing and snagging. 20lb+ catfish are common. The Arkansas Post is only minutes away for hiking trails and bike rides.

Superhost
A single-story home presents a classic brick façade with a prominent garage. The well-kept yard features neatly trimmed shrubs and lush greenery. The driveway leads to the garage, providing ample parking space. Large windows allow natural light to enter the living spaces.
Home in Clarksdale
4.72 out of 5 average rating, 176 reviews

Down Home Southern Charmer

This is the home that my sister and I grew up in with our parents and younger brother, who have passed on. We love our home, and are now opening it up to guests from anywhere in the world who want a comfortable place to stay while visiting the Mississippi Delta. Available to our guests are a centrally heated and cooled home with two bedrooms, a living/dining room, a family room with TV and Internet, two bathrooms, a kitchen, washer and dryer, and a garage. And, we just put in new floors!

Guest favorite
A cozy living area features two light-colored sofas opposite each other, adorned with decorative pillows. An intricate area rug covers the floor, complementing the rustic wooden walls and high ceiling. A room divider is positioned in the background, dividing the space from the bedroom. Natural light filters through the nearby windows.
Cottage in Clarksdale
4.91 out of 5 average rating, 321 reviews

Sunflower Cottage on the River

Only a mile from historic home of the blues, Clarksdale in a gated community. The cottage sits on the banks of the Sunflower River with beautiful views of rustic woods. Out your window you might see deer, fox & other wildlife. Take a walk along the riverbank. You’ll enjoy relaxing in the comfy beds, ,enjoy privacy, the piano , & closeness to all the blues music venues. It has two fire pits, an outside grill & full kitchen. Great for couples, adventurers, business travelers , musicians ,

Guest favorite
A charming blue cottage features a gabled roof and a white front door framed by two light fixtures. Two vintage chairs are positioned on the grassy area in front, surrounded by mature trees that provide some shade.
Cottage in Clarksdale
4.82 out of 5 average rating, 175 reviews

The Gallery at Chateau Debris

Welcome to The Gallery! This one-bedroom cottage sits behind the main house. It has recently been renovated, but is decorated with vintage furnishings for personality. The cottage is equipped with a full kitchen, bedroom, bathroom, washer and dryer, & Roku TV. Your stay will be unique, as the decor has been selected from my collector's lair, and the best part is - it's all for sale! The Gallery is a live-in collectibles showroom so, contrary to the saying - you CAN take it with you!

Guest favorite
Home in Dumas
5 out of 5 average rating, 35 reviews

Water front 5 bedroom 2 bath Pendleton Point

Arkansas River waterfront 5 bedroom 7 queen size beds 2 bathrooms with two large patios and grill/smoker. Downstairs has a kitchen, laundry room, living room, 2 bedrooms and bathroom. Upstairs has 3 bedrooms and a bathroom with a separate living room. Hunting and fishing available nearby boat access. (Trusten Holder wildlife refuge, White River refuge & more.) There is a family park less than a mile from location. The Arkansas Post is minutes away for nature trails and bike rides.

Guest favorite
A modern gourmet kitchen is presented with sleek cabinetry and contrasting black and white elements. A spacious island with seating for four is illuminated by pendant lights. Open shelving displays dishware, while the stainless-steel appliances enhance functionality.
Apartment in Helena-West Helena
4.88 out of 5 average rating, 34 reviews

Luxury Apartment Downtown Helena

Conveniently located near historic landmarks, local shops & renowned dining establishments. Explore the rich cultural heritage of Helena, from museums to live music venues, all within walking distance. Amenities • Self-check-in • Video surveillance/exterior of building • High-speed Wi-Fi • Smart TV • Coffee machine • Central air & heating • Free reserved parking on premises • Responsive & accommodating hosts • Strict cleaning protocols • Safe & secure building

Guest favorite
A rustic cabin is elevated on stilts, surrounded by lush greenery and trees. The wooden structure features multiple entries and a porch, while an open grass area extends around the base, providing a sense of space and tranquility.
Cabin in Stuttgart
5 out of 5 average rating, 20 reviews

Mud Lake Lodge

An amazing hunting and fishing cabin right inside the duck capital of the world. Bring the family for a weekend getaway filled with food and camp fires. Seconds from the boat ramp into the crappie filled mud lake off the arkansas river, or a short drive to the famous bayou meto to enjoy green heads pouring through the trees with friends. Countless memories can be made with a trip to the woods. The fun is waiting.

Guest favorite
The exterior of a single-story house is highlighted by a well-maintained lawn, framed by trees. Light-colored siding and brown shutters complement the entrance, which features a white door and a welcoming open porch area.
Home in Marvell
4.95 out of 5 average rating, 21 reviews

Tranquil home away from home

Relax with the whole family at this peaceful place to stay. The Parsonage accommodates everyone! 3 bedroom, 2 bath home in the center of town immersing you in a little slice of home. The house has two separate living areas, an eat-in bar, dining room and a fenced in backyard and storage building available if needed during your visit or hunting trips.

Popular amenities for St. Charles vacation rentals

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