Guesthouse vacation rentals in Pickens County

Your Charming Country Cottage

Whether you need a country getaway or a place to lay your head after a football game, our cottage in the foothills of upstate SC is the perfect spot for both. You’ll find us tucked away just outside the quaint little town of Six Mile, 10 miles north of Clemson University and in close proximity to 3 of the upstate's favorite lakes: Lake Keowee, Lake Jocassee and Lake Hartwell. Here you’ll enjoy the serenity of country life without feeling “too far out" or away from all the upstate has to offer.

Mountain Cabin on Creek at Jocassee Gorge.

Welcome to Laurel Valley. A tiny, sleepy neighborhood at the top of a mountain, hidden from the hustle of civilization. This adorable cabin is nestled in beautiful Jocassee Gorge. Minutes away from multiple attractions including Sassafras Mountain and Twin Falls. Property borders thousands of acres of protected land with 5 star trails . This mountain cabin is in a unique setting that time forgot. The rushing creek outside helps you to peel off the world and get a great night's sleep.

Fairy Forest Cabin with Hot Tub at Table Rock

Adventure and relaxation await you! Set half a mile off the road, surrounded by forest, you’ll feel like you’re far away from the demands of life as you soak in the hot tub. But you are right in the golden corner of SC, NC, GA mountains with the best of hiking, kayaking, cycling and dining nearby! Only 28 miles from Greenville, Clemson and Brevard NC with Table Rock State Park and Lakes Jocassee and Keowee a few minutes away. The perfect couple’s getaway! Use of SC State Park pass included.

Elfwing Carriage House

Bright & comfortable studio apartment located in a quiet family neighborhood in the country, yet minutes to town. We are an easy 15 minute drive to Clemson, less than 5 miles to SWU, 7 miles to Duke Energy. Smart location for the mountains & lakes, visiting colleges, and graduation. Tiger tailgate space available for an additional fee. Hikes, waterfalls, 12 Mile river & Lake Hartwell are nearby. Friendly dogs are fenced or in our home. Come enjoy neighborhood & country living at its finest!

Lakeside Haven on Lake Keowee

Relax at this cozy lakefront studio on Lake Keowee with access to kayaks, paddleboards, a dock, fire pit, and pool. Perfect for unwinding or exploring, it's close to state parks with hiking trails and just a short drive to Clemson University-great for football weekends. The studio includes a full kitchen, private bath and in-unit washer/dryer providing all the comforts of home. Whether you're here for adventure or relaxation, this lakeside retreat has everything you need.

La Bella Farm

Do you want to be close to Clemson(11 miles), Anderson(9 miles) OR Greenville(20miles)! Do you want to just get away from all of the noise and busy life. Then you have found your spot! This is a great detached garage apartment. Settled in the quiet country side of Pendleton SC. 1 bedroom&1 bathroom with an additional sofa bed&blow up mattress. Great view of nothing but beautiful land from the kitchen window yet minutes away from Death Valley,restaurants,shopping and 85.

Little Blue Cottage on the Jocassee Wilderness

Little Blue, named because it's surrounded by wild blueberries, is situated just steps from the Jocassee Wilderness Area listed by National Geographic as 9th out of “50 of the World's Last Great Places.” It's located on the property of Heart Ridge Retreat Center. Guests will have access to all the retreat center grounds which includes a well-stocked lake (bring your rod). It's also centrally located to many trails, waterfalls, state parks, and lakes.

Holly Hideaway! 10 Highway miles to Clemson U!

Holly Hideaway is nestled between Greenville and Clemson, in the small town of Liberty. It's perfect for business travelers, couples, Clemson parents, alumni, and small families. Tiled throughout for cleanliness. Privacy, tranquility, and clean, comfortable accommodations are what we provide. We are 10 minutes from Clemson and 3 miles from SWU. The Hideaway now offers Wi-Fi and Smart TV.

Cozy Greenville Guest Suite w/ Fire Pit

Relax in this clean, comfortable guest suite featuring a cozy bedroom, bright kitchenette, and private bathroom. Start your day with a fresh cup of coffee or unwind by the fire pit, surrounded by peaceful woods and quiet nature views. This private space is perfect for solo travelers or couples looking for a calm, convenient Greenville stay with all the essentials.

Gilded Frog Guesthouse. Rainfall Shower, King Bed

Welcome to the Gilded Frog Studio. Conveniently located between Greenville and Easley and only minutes from I85, we are positioned right in the heart of the growing Powdersville area. Whether you're visiting Greenville or looking for a local place to stay to catch a Clemson game, we offer the amenities you need to make your stay effortlessly enjoyable.

Nested Studio Woodscape

Escape to our modern rustic and refined small studio apartment, nestled in the country. Tucked away in the trees, it sleeps four, with one bathroom. Experience the perfect blend of serene seclusion and contemporary comfort in this charming retreat. Ideal for nature lovers and close to nearby attractions. Book now for an unforgettable getaway!

The Rabbit Hole near the Swamp Rabbit Trail

Welcome to The Rabbit Hole. Escape to our serene retreat, ideal for families and furry friends alike! Nestled just 3 minutes from the scenic Swamp Rabbit Trail and a quick 6- minute drive to downtown Travelers Rest, our cozy haven is the perfect home-based for exploring the beautiful upstate region, including nearby Furman University.