Vacation rentals with lake access in Pickens County

Find and book unique lake access rentals on Airbnb

Top-rated lake access rentals in Pickens County

Guests agree: these lake access rentals are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favorite

Guest suite in Greenville

4.9 out of 5 average rating, 314 reviews

Lakefront luxury private guest suite 6mi to DT

MINI PRIVATE OASIS. 6 MILES TO DOWNTOWN GREENVILLE! LAKEFRONT + PRIVATE DOCK NY Times #1 AMERICAN CITY! Experience modern luxury in your serene private mini suite. Please note: the suite is located as an extension of classic Scandinavian chalet - no shared spaces, 1 shared soundproofed wall. 6mi downtown Greenville, 5mi Traveler’s Rest - Private dock - Private entrance & flower-friendly patio - 43” Roku TV - Charcoal grill, fire pit, outdoor seating - Luxury amenities - Blackout curtains

Superhost

Home in Greenville

4.88 out of 5 average rating, 121 reviews

15 Fisher's Paradise on Lake Saluda w Boat Ramp

Stay at Saluda Lake Landing in this unique lakefront property getaway that has a house, cafe, boat ramp, and dock. Perfect for fishing, kayaking, paddle boarding and more. Once home, relax and cook the days catch indoors and out. This property is partially public as we do get other customers for the cafe, dock, and boat ramp. Please be aware that our employees will be around the property during normal working hours. If you are planning to bring your furry friend with you please reach out as we

Top guest favorite

Cottage in Seneca

4.99 out of 5 average rating, 101 reviews

Destination Keowee

A rustic industrial style Lake Keowee lakefront escape that places you right on a panoramic point in a private cove. Welcome the outdoors in with the 6ft kitchen hinge bar window to the upper deck or enjoy the 6-seat hot tub on lower deck. Deep water dock tie off space is available. Guests enjoy the use of 2 standup paddle boards, and lakeside fire pit (guest provide firewood). Great cove sunsets! 15 minutes to Clemson and 1 min Lighthouse Restaurant. Please read all details prior to booking!

Guest favorite

Cabin in Six Mile

4.95 out of 5 average rating, 116 reviews

Beautiful cabin retreat at Lake Keowee

Charming, remodeled cabin with loft across from Lake Keowee. Perfect to unwind, recharge, and create memories in this idyllic retreat. Centrally located to Six Mile, Salem, Seneca, Clemson, Walhalla, and the numerous state parks, trails, and waterfalls! Quaint community has a private pool with facilities and outdoor shower. We also have a private, community day dock across the street for easy lake access, fishing, and swimming. Less than 5 minutes is Warpath Landing a public boat ramp.

Top guest favorite

Home in Seneca

4.99 out of 5 average rating, 192 reviews

Lakeside @ Lake Hartwell in Clemson, SC 🐟🌅🚤

Lake lovers and college football fans...you will LOVE this house! Lots of privacy, huge kitchen, dock, fire pit, gas grill, kayaks, and more! Beautiful Lake Hartwell home… where 1000 miles of shore awaits you! Our home is located just minutes away from Clemson, Seneca, Anderson, and more! Just 25 steps to your private dock, and 7 miles/ 10 mins from Death Valley (Memorial Stadium!) 4 bedrooms, and 3 full bathrooms. You must be at least 25 to rent. NO pets allowed, sorry! No fireworks.

Guest favorite

Condo in Salem

4.96 out of 5 average rating, 130 reviews

Beautiful Lake Keowee Condo with great Amenities

"Boasting lake views, a fully equipped kitchen, and resort-style amenities, this 2-bedroom, 2-bath Salem vacation rental condo in Keowee Key will have you experiencing the true meaning of life on the lake. Cool off with a dip in the community's outdoor pool which sits right next to the marina where you can rent a boat for a day out on the water. Tee up a round of golf on the renovated 18-hole course, walk along the trails of Oconee State Park, or catch a football game at Clemson University!"

Superhost

Home in Six Mile

4.85 out of 5 average rating, 230 reviews

House on Lake Keowee swim beach in cove w/ Dock

This two story home is located at the end of a very quiet cove with plenty of water. The beach has a fresh 6 inches of sand installed for the lake season. The walk to the lake is very short on an almost flat surface. The home will accommodate a family up to six people. The house has two floors. The main floor has a large living room with plenty of comfortable seating and satellite TV service provided. The entire main floor has hard woods along with the Master Bed Room and bed room #2.

Top guest favorite

Home in Six Mile

5 out of 5 average rating, 10 reviews

Lake Keowee SC Lakehouse Escape

Bring the whole family to this Great Lake Keowee home near Clemson SC. Enjoy lake fun in lots of beautiful comfortable space.4-bedroom, 4.5 bath vacation rental house in Six Mile, SC! Directly on Lake Keowee enjoy newly decorated very clean/organized spacious property. Easy walk to lake will enjoy 1 boat parking spot, 2 jet ski lifts, kayak, paddle boat, lake floats. Enjoy lots of outside space: top deck lounge chairs, pick nick tables on the deck, large outdoor seating porch & sunroom.

Top guest favorite

Home in Seneca

4.96 out of 5 average rating, 142 reviews

Lake Hartwell house w/ dock 2 miles from Clemson.

This is a simple, comfortable, recently renovated home for Clemson fans and lake vacationers. Decor is vintage/antique. It is 3 1/2 miles to stadium entrance. We have a deep water cove with fire ring, decks, dock, and stairs to gangway, parking for 6 cars, woods and lake on 3 sides, a variety of restaurants nearby. Clemson Marina is next cove over. Clemson golf course across the lake. We are PET FRIENDLY with a max of 2 dogs. There is a $75 pet fee. Read the house rules concerning pets.

Guest favorite

Cabin in Six Mile

4.93 out of 5 average rating, 149 reviews

Lake Keowee, Waterfront Cabin, 2-Story Dock!

Beautiful cabin 15 min from Clemson Stadium. Brand new to the rental market. Boasting cathedral ceilings, this home offers an open floor plan for everyone to gather. Sleeping 10 with 4 bedrooms and 3.5 bathrooms and 2 living rooms, there is space for everyone. Steep incline from lake to house with paved stairs. Tram from deck to dock! Fire pit with wood provided. Large deck and covered porch. Large covered dock for your boat with 650 sq. ft. second floor sundeck. 2 car garage.Hot Tub!

Guest favorite

Home in Six Mile

4.96 out of 5 average rating, 68 reviews

Lake Keowee Beach Club Cabin

Relax with the whole family at this peaceful and spacious log cabin home on beautiful Lake Keowee. Views of the emerald water from all four bedrooms, wrap-around porch. Two accesses to the lake! Private beach and private dock across private street. Gently wade into the water for protected swimming and kayaking. Perfect little beach great for the kiddos! Three levels. Master bedroom ensuite is on the main with access to a covered porch. Two bedrooms up with the fourth on terrace level.

Top guest favorite

Home in Salem

4.99 out of 5 average rating, 127 reviews

Keowee Key Luxury Condo - Stunning Views!

Freshly renovated condo at the sought after Tall Ship condos in Keowee Key. This is hands down the best unit the complex has to offer with amazing views. Enjoy grilling out on the patio overlooking the marina, walking on the trail, or relax in the pool which is only a short walk away. This is truly a paradise. Guest boat slip is available at the marina for boats or jet skis. Slip is $50 per day. Recommended to book one month in advance.