Townhome vacation rentals in Pickens County

Resort Pool & Spa 3BR 3BTH w Loft, Family Gameroom

Escape to this spacious three-story, family-friendly home w bedrooms, baths, and decks on each level—perfect for large families (sleeps 9). Pack ’n Play available, easy front-door parking, & access to resort pools, spa, and sauna included. It's a professionally cleaned, dog-friendly 3BR, 3BA townhome w loft/3 living spaces. Enjoy wooded rolling hills w wildlife, resort amenities (some activities like golf or boat rentals have fees), ping-pong, board games, and a deck fireplace under the stars.

Rosehill Villa at Clemson Botanical Gardens

Newly renovated 4 bedroom 3.5 bathroom townhouse. Open concept kitchen, living room and dining room. Small deck located off the kitchen and dining room to relax with coffee. Bring the whole family to this great place with lots of room for fun. Clemson Botanical gardens are a 10 minute walk down a foot path and continue on for another 25 minutes to reach Memorial Stadium (football), Littlejohn Coliseum (basketball), Doug Kingsmore Stadium (baseball), and Brooks Theater where the Tigers play.

Updated Lake Keowee Resort |25 min to Clemson

Welcome to our spacious 4-bedroom, 3-bathroom townhome in the gated Keowee Key Resort community, where lake life, mountain views, and resort amenities come together for the perfect getaway. Spread across three levels with two living rooms and two sunrooms, the home offers plenty of space for families, couples, or friends traveling together. Whether you're visiting Lake Keowee, Clemson University, or the Blue Ridge Mountains, this home is a comfortable base for both adventure and relaxation.

Brand New Build Clemson Retreat 3br/3bath sleeps 8

This is a brand new build, two story townhouse. Comfortably sleeps 8. All new furnishings. Kitchen has all that you need to host a football weekend, graduation party or special dinner. All 3 bedrooms have en-suite full bathrooms. Sleeper sofa has Queen gel foam mattress. Kitchen fully stocked. Walking distance to Clemson, and Botanical Gardens. Short drive to restaurants in Patrick Square downtown Clemson and Pendelton. Three parking spaces assigned to house. Truly great location!

5 Mi to Memorial Stadium & Beach: Modern Townhome

Recently Built | Dine Al Fresco Reconnect with family or friends and experience the best of Central, South Carolina, when you stay at this airy vacation rental! Tour Clemson’s vibrant campus, cheer on the Clemson Tigers, or simply soak up the sun along Lake Hartwell while the kids splash around in the water. Staying inside? Boasting 3 bedrooms, 2.5 bathrooms, an open-concept living area, and 2,500 square feet, this townhome provides plenty of space for everyone!

Walk to Lake Keowee: Salem Townhome w/ Deck

Walk to Private Beach | Fireplace | Newly Renovated | 10 Mi to Clemson Escape to this 4-bedroom, 3-bath vacation rental in Salem! Perfect for families, this townhome offers ample space to unwind after exploring Lake Keowee or Table Rock State Park. With a full kitchen and access to community amenities, this townhome has everything you need for a memorable retreat! Be sure to relax by the community pool or play a round of golf before cozying up by the fireplace!

Exclusive Luxury Escape

Welcome to this cozy place in Easley, SC—perfectly located between Clemson and Greenville! Just 20 minutes from Clemson University and downtown Greenville, this space is ideal for college visits, game days, or exploring the Upstate. Enjoy a quiet, comfortable stay with modern amenities and easy access to local dining, shopping, and outdoor activities. Whether you're here for a Tigers game or a weekend getaway, our home offers the perfect base for your adventure.

Spacious Modern Loft 2BR 2.5 BA Greenville Clemson

Unwind in this sleek modern townhome with all the modern amenities, blocks away from downtown Easley. - Just 18 miles from Clemson and 13 miles from downtown Greenville. - Full Kitchen - 2 comfy bedrooms - 2.5 baths - private balcony - Just 5 Minute walk to Silos food hall and doodle trail. - Free Private Parking! The Bonnie is the perfect location for game weekends & family visits w/ college kids, business travel! Book your stay before the calendar fills!

Boat Dock: Lake-View Retreat 5 Mi to Dtwn Clemson

Whether you're here for a relaxing lakefront getaway or to cheer on the Tigers, this impressive Seneca house is the perfect choice for you! Ideally situated on a private lot of nearly one acre on picturesque Lake Hartwell, this vacation rental boasts ample deck space, three screened porches, and a media room perfect for watching the big game. You'll love being within four miles of Clemson University, museums, parks, shops, restaurants, and more!

Keowee Key Townhome with Amenities - Pet Friendly

We are a pet friendly townhome so your puppy baby can vacation with you as well. This pristine community nestled in the foothills of the Blue Ridge Mountains surrounded by Lake Keowee features 2 marinas (plus kayaking or canoeing), 2 outdoor pools, and indoor Olympic size pool plus fitness center, on-site restaurant and the Bistro cafe. Feel free to go leisure walking on the trails throughout the compound which is all easily accessible.

Tiger Nest in Clemson, SC!

Tiger Nest - Luxury Townhouse Retreat in Clemson, SC Welcome to your perfect getaway! Our high-end townhouse, newly constructed and nestled in a serene neighborhood just outside of Clemson, SC, is your ideal home away from home. Designed with elegance and comfort in mind, this spacious and modern property offers everything you need for a relaxing and memorable stay.

TigerTown HideAway

Perfect spot for your visit to Clemson. 4 bedroom/4.5 bathroom close to everything. Property backs up to Clemson’s Botanical Gardens. Beautiful Lake Keowee and Hartwell is a short drive away. Lake Jocasse is about an hours drive. 2 minute drive to downtown. Near restaurants and grocery stores. This townhome can sleep 10+ Anderson - 15 min Greenville -45 min