
House vacation rentals in Pickens County
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Top-rated house rentals in Pickens County
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Welcome to Downtown Pickens
This beautiful brick home located on a spacious lot is waiting for you! Your family will be close to everything when you stay at this centrally-located place. 3 spacious bedrooms and 1.5 baths will make life a breeze. Dine or relax on the covered patio while the kids play in the gently sloping private backyard. Your stay on West Main St will be a dream with all the amenities of downtown Pickens being in walking distance. You are also only 20 minutes from all Greenville or Clemson has to offer.

Modern Wooded Retreat
Come enjoy this modern, 1.6 acre retreat! Relax with the whole family in a place you'll never want to leave. Located 5 min. to downtown TR and less than 20 min to downtown Greenville! Roast marshmallows by the firepit, play yard jenga, connect 4 and cornhole in the fully fenced, dog friendly back yard. Close to the swamp rabbit trail, and centrally located to lakes, hiking, fishing and exciting nightlife. Let us host you, while you explore everything Greenville and Travelers Rest have to offer.

Basement apartment in Pendleton w/ sep. entrance
This is a basement apartment in my personal home with its own separate entrance, bathroom, and kitchen. Parking is on the street in front of the house and there’s a concrete walkway that takes you down to the entrance. It’s a studio style apartment with your own thermostat, a king bed, ceiling fans, over 500 sqft, and a fenced backyard for your pup if you bring one. Minutes from Clemson University, T ED Garrison Arena, I85, and 40 min from downtown Greenville. Hulu Live is provided on the tv

Comfy, cozy duplex apt in old home downtown Easley
Comfortable, CLEAN, safe, serene, remodeled duplex apartment w/private entrance thru back of home - 20 mins to Gville/Clemson. Stocked for cooking. Near hiking, climbing, kayaking, diving, fishing, restaurants, breweries, pubs, theatres, museums, hospitals, live music venues, shopping, universities, and churches. Come home to comfy robes and rooms designed for relaxation. Note: Easley has a train track downtown - a few blocks away. This is important to note. Self check-in thru passcode

3 Bed Home Overlooking Fishing Pond on 10 Acres
This Home is a retreat in of itself! All New Accommodations offer Large eat in Kitchen, Primary Suite with Primary Bath. Stocked Fishing Pond! Peaceful and relaxing property to enjoy privately. If you are a foodie or shopper Greenville is only 15 miles away. Greenville has landed on countless "best of" lists so it's a must see! If Clemson is what you love we are twenty minutes from campus! Business class wifi too and cable TV Enjoy Great hiking at one of the close state parks too

Cottage in Pickens
Enjoy easy access to all the Upstate has to offer! This newly constructed 2 bedroom, 1 bath duplex apartment is located along the Doodle Trail bike route. Enjoy hiking trails and waterfalls at Table Rock and Caesars Head State Parks, catch a Clemson football game, or check out Falls Park and downtown Greenville, all from one convenient location! The home is across the street from a well-maintained local park and playground and within walking distance to a coffee shop and restaurants.

Comfort & Convenience Close to Campus
The perfect blend of modern charm and full comfort & convenience just minutes from Clemson, The Pendleton Square and HWY access. You will be sure to have everything you need for your visit. Comfortably sized bedrooms with queen size beds. Spacious living area with cable TV & Netflix. Bright and open kitchen and dining fully equipped for all your cooking needs. Whether you're traveling alone for a little peace & quiet, with friends, or with family... we hope you enjoy your time here!

Our Slice of Heaven w/Views of Table Rock-Pickens
Our slice of heaven is located in the foothills of the Blue Ridge Mountains only 8 mins from Table Rock State Park. Our guest house is sitting on 55 wooded acres with our 4-acre pond and amazing awe-inspiring panoramic views of Pinnacle and Table Rock Mountain. Wrap yourself in the serenity of nature, with nothing more to wake you in the morning than the pleasant sounds of songbirds beckoning you to delight in the new day.

Spectacular Lakefront Retreat on the Saluda
Stunning views, quiet, still waters, wildlife in its natural habitat. This and more is what you'll find at Lakepoint on the Saluda. Better yet, this property is located on the water with 460' of lakefront and is just minutes from downtown Greenville, Furman, and Paris Mountain. Within 35 minutes you can be in Clemson. Includes kayaks, a canoe, hot tub (SEASONAL), work out room, and some of the best fishing in the upstate!

Hidden Retreat
4 private acres just off Hwy 11. HIKE - connector to the Palmetto trail and Table Rock State Park. BIKE - popular biking routes; Hwy 11, Hwy 288 and Hwy 178 + Doodle & Swamp Rabbit Trail. GOLF - 1 course 5 minutes away several others nearby. WATERFALLS - including the highest in the east. MOUNTAIN LAKES - 2 of the best, Jocassee & Keowee. HIDDEN RETREAT - close to many outdoor adventures. Up to 6 guests.

Livin' Easley-walk to downtown-close to everything
Welcome to Livin' Easley! Your family will be close to everything when you stay at this newly renovated bungalow style house. Downtown Easley shops, restaurants, bars and The Silos are within walking distance, and Greenville and Clemson are just a short drive away. If you'd rather stay in, enjoy everything the house has to offer including bumper pool, a card table, board games, horseshoe pits, and Netflix.

The Little House @ Cozy Hollow
Country living close to town. 2 miles from Cateechee Beach Park, 4 miles from SWU, 10 miles from Clemson, 12 miles from Oconee Nuclear Station, 13 miles from Garrison Arena, and 25 miles from Greenville. Enjoy your getaway at this private guest house with private drive, front & back porches, tv (streaming via Hulu Live, Disney+, Netflix, and more), washer/dryer, and full kichen including Keurig.
Popular amenities for Pickens County house rentals
House rentals with a pool

Keowee Key Luxury Condo - Stunning Views!

Hideaway at Hunting Hollow with pool-close to lake

Lake Keowee Access-Dock-Pool-Grill-Clemson 17 Min

Historic Pendleton SC

Golf view, lake access, 3 pools!

* Keowee Key* Lake* Fireplace*Golf*Tennis*Gym*

Cottage close to Clemson

Tiger’s Lair
Weekly house rentals

Elegant 3BR Near Wed Venu | Grill+ Golf Next Door

Singing Pines Cottage

Pickens Place Unit A

12 min to Clemson | Quiet home in small town S.C.

Tekoa at Table Rock

Rare 1930’s Riverfront Cottage

Grand Slam on Nalley 2BR by GVL & Clemson

Calhoun Cottage
Private house rentals

The Blue Lodge: 14 mins Peace Hall, Falls at Reedy

Cozy Foothills Retreat

Spacious Lakefront *Gem* Pet & Family Friendly

The Retreat in Travelers Rest

Modern home near Clemson, Keowee

Five Ponds Lane

Robin’s Nest- Cottage in the Woods

Peaceful Mountain Home on Pond with Private Dock
Destinations to explore
- Pet-friendly rentals Pickens County
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- RV rentals Pickens County
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- House rentals South Carolina
- House rentals United States
- Blue Ridge Parkway
- The North Carolina Arboretum
- Black Rock Mountain State Park
- River Arts District
- Gorges State Park
- Chimney Rock State Park
- Ski Sapphire Valley
- Tallulah Gorge State Park
- Table Rock State Park
- Lake Lure Beach and Water Park
- Clemson University
- Jump Off Rock
- Tryon International Equestrian Center
- Biltmore House
- French Broad River Park
- Woolworth Walk
- Harrah's Cherokee Center - Asheville
- Thomas Wolfe Memorial
- Carl Sandburg Home National Historic Site
- Saint Paul Mountain Vineyards
- Burntshirt Vineyards
- Bon Secours Wellness Arena
- Overmountain Vineyards
- Fred W Symmes Chapel




