
House vacation rentals in Picayune
Find and book unique houses on Airbnb
Top-rated house rentals in Picayune
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Picayune house rentals
House rentals with a pool

Cozy Country Cottage with Pool

Heated Pool, Hot Tub, Boat/Fish Dock, No pet fees!

Myrtle’s place, a Charming home with a pool!

Spencer’s Way Beach House A with heated pool

Secluded Palm Hideaway w/ Resort Style Pool

Gulf Moon Beach House II Waterfront Home with pool

Luxurious Five Bedroom With Pool

Waterfront Comfort With Pool - Sleeps 8!
Weekly house rentals

GaMe RoOm, Sleep 12, Colorful Back Yard, Beach(A)

Hair of the Dogs, Renowned Remedy, Old BSL #BSL026

Secluded Beach House with Amazing Views 5 Bedrooms

Beautiful Home on the MS Gulf Coast

Southern Oaks Historic Abita- Walk to Downtown

One-Bedroom by Beach

Weekly, Monthly, KAFB military, & More Discounts

LB Lodge-Walk to the Beach, 12 eateries & 2 Parks
Private house rentals

Brand New Modern Waterfront Home

Farmhouse Charm w/cabin, firepit, & hot tub

Victorian Cottage with a Modern Touch! ~ 4BR/2BA

Colorful Bay Retreat minutes to town + beach

Blu-Mae Marie Beach House

MS Gulf Coast Home near Beach, Casinos & downtown

New beach front home view from porch on beach side

Restful Retreat | Pool & Game Room
Quick stats about house rentals in Picayune
Total rentals
20 properties
Nightly prices starting at
G$6,276 GYD before taxes and fees
Total number of reviews
260 reviews
Family-friendly rentals
10 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with dedicated workspaces
10 properties have a dedicated workspace
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- St. Louis Cemetery No. 1
- Biloxi Beach
- Tulane University
- Smoothie King Center
- Get Wet
- The National WWII Museum
- Mardi Gras World
- Saenger Theatre
- Fontainebleau State Park
- Mississippi Aquarium
- Buccaneer State Park
- Fallen Oak Golf
- English Turn Golf & Country Club
- Gulf Island National Seashore
- Steamboat Natchez
- Money Hill Golf & Country Club
- Milićević Family Vineyards
- The Beach
- Grand Bear Golf Club
- Louis Armstrong Park
- New Orleans Jazz Museum
- Amatos Winery
- Backstreet Cultural Museum
- Crescent Park