
Family-friendly vacation rentals in O'Fallon
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in O'Fallon
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

Cozy Home in Wentzville Sleeps 6 + Game Room
Welcome to your home away from home in Wentzville, Missouri! Families and furry friends are welcome to our cozy, centrally located home. Sleeps 6- 1 King , 1 Queen, and 1 Sleeper Sofa Full sized bed Fully equipped Kitchen with everything you need to create a delicious meal, or a cup of coffee Game room and Laundry located in the basement- 60 game free play arcade machine and foosball! Roku friendly TV located in both bedrooms, living room and on the Patio Fully Fenced Yard with Fire Pit

301 Guesthouse- Historic Main street-Katy Trail
Our 301 Guest House is new and completely remodeled in 2018! It’s ideal for one or two people with beautiful furnishings, great queen bed, lots of amenities, full kitchen, with big back yard and patio to enjoy outdoors too! Cable and FAST WiFi! Enjoy light Breakfast! BEST location, Great events year round within walking distance, with being only about 2 blocks from S. Main St, where there are about 100 gift shops n restaurants! Katy Trail is so close, with Spring, Summer, Fall and Xmas events!

Charming Pop Lucks Guest Suite in Old St. Charles
Welcome to Pop Luck's Guest Suite! This adorable gem represents everything you love about Old St. Charles. This cozy suite is just steps away from the heart of Main Street, restaurants, and all the action St. Charles has to offer. Pop Luck's is a charming one-bedroom, with an open and airy living room and kitchen. It has natural light and high ceilings throughout. It's farmhouse cottage decor makes for a relaxing place to rest. Also, check out our sister suite The Ella Rose, right next door.

The Zen Den - Centrally Located, Calm and Tranquil
The Zen Den was conceptualized out of a desire to create a calm and peaceful oasis centrally located in the North Hampton neighborhood of St. Louis where parks, cafés, restaurants, and entertainment are only minutes away. The space features modern appliances, contrasted with soft light features and natural building materials, such as reclaimed lumber, to convey a sense of calm and tranquility. Ideal for those guests seeking to retreat at the end of a busy day exploring or remote working.

Treehouse Spa Suite
Treehouse Day Spa is nestled on 3 wooded acres in St.Charles County. There is a subdivision next to me but I have my trees!!! Get away from it all while being close to it all at the same time. Augusta wineries, Main Street St. Charles and the Streets of Cottleville are all within minutes of the location! There are two rental units in the treehouse: The spa suite and the penthouse. They each have a separate entrance and are private spaces. Recharge your battery! Regroup Relax Refresh

Bright & Cozy Shotgun DPX 1 Block from Historic DT
Admire this unique historic home's design with brand new amenities and antique details that give a fresh and charming feel. Built in the late 1800's, this half of the duplex has a typical shotgun layout with ten-foot ceilings giving a spacious feel. The front door leads directly to the living room, then into the bedroom, both of which have the original hard wood floors. The back of the house has the kitchen, with exposed brick, a dining area, and a bathroom with a washer and dryer.

Cozy Studio in Beautiful New Town St. Charles
Stay at this cozy studio centrally located in the amazing community of New Town St. Charles. New Town is a large scale new urbanist community built on the edge of suburbia. You never have to leave New Town with its walkability to restaurants, bars, a market, coffee shops, ice cream, food kiosk, canals, lakes, parks and tree lined streets. If you do leave its only a few miles from historic St. Charles Main street, The Streets of St. Charles, and 25 miles to Downtown St. Louis.

Family friendly 3bd home! Longer stays available
Peaceful, 3 bed, 2 bath on court in O’Fallon MO. Furnished kitchen, deck grill/dining, tv in bdrms/living space, lower level living area & ping pong. Serene, fenced in back yard for your morning coffee. Located near shopping, restaurants, bars, casinos, wineries, gyms, hospitals, sports complexes & major highways. Just a 30 minute drive to downtown St. Louis, Enterprise Center, Busch Stadium, Forest Park, Zoo & Arch, 15 minutes from Lambert Airport, Hollywood amphitheater..

2nd Street Loft - Riverview
Complete Rehab, this historic 1883 storefront building hosts a well known artist and his gallery on the 1st floor. Above is your "loft space" close to wineries, Amtrak, featuring great views of the Missouri River. You’ll love this Downtown Washington location because of the walkable shops, bars, and restaurants many in historic buildings. The loft is great for couples, solo adventurers, and business travelers who can walk a flight of stairs.

The Ladybug Inn
This stylish place to stay is perfect for group trips. I have personally renovated this entire ranch style home. It has plenty of room for the whole family! You will find everything you need for a comfortable stay. Conveniently located near the heart of Wentzville. I also have another location in O'fallon Missouri if this property is not available for the dates you are needing it. Please search Beautiful 2 bedroom ranch home in O'Fallon MO.

Family Friendly Home Near Parks and Dining
Enjoy a relaxing experience at our conveniently located home in St. Peters. This 3 bedroom 2.5 home is fully stocked and ready for your family to visit. The neighborhood is quiet and within walking distance of a lovely park with walking trails, a playground, and ball fields. We are also minutes away from groceries, dining, and the St. Peters Recplex. We cannot wait to welcome you to our space for your next get away!

Comfy 3BR home in heart of Saint Peters
Enjoy your stay in the Saint Louis metro area at our safe, clean, and comfy home in Saint Peters, MO - which was recently ranked by Money Magazine as the #1 city in Missouri to live in. Our home is close to dining, shopping, parks, walking trails, and freeways. Many restaurants, as well as groceries, pharmacies, and other services are within walking distance. See our extensive guidebook for additional details.
Popular amenities for O'Fallon family-friendly rentals
Family-friendly home rentals with a hot tub

“HOT TUB” Oasis in the heart of the city!

Cedar Hot Tub & Cedar Sauna, Chalet at Innsbrook

White Lotus Hideaway | Hot Tub on Main Street

Romantic Augusta Cottage-Relax & get away!

Roomy Oasis with hot tub on the Hill!

Secluded Lakeside Lodge Minutes from St. Louis

Blair's House in St. Charles - Game Room - Hot Tub

The Honey Bee Inn by Innsbrook Vacations!
Family- and pet-friendly home rentals

Forest Edge Tiny House | 8 Min to Airport

TJ’s Country Getaway *Dog Friendly*

ArtBnB: Enjoy the Curated Comforts of Home

Pacific Palace, super unique!

Route 66 Railroad Shanty, a cozy artsy small space

Relaxing Oasis with Free Bottle of wine+brkfst

Colorful Comfort

Beautiful Unique Home | Walk to Botanical Gardens
Family-friendly home rentals with a pool

Private indoor pool & sauna

Early Check-in, Late Check-out on Weekends 8AM-8PM

Peaceful Lakefront Chalet w/Dock and Boats!

Pura Vida Chalet - Lakefront on Lake St. Gallen

Spacious Home - Central Location - Amenity packed

Sunset Mountain Forest Privacy

T Luxury Pool, Hot-tub, PickleBall, Arcade&Theater

Peaceful chalet - *new* private beach, WIFI, kayak
When is the best time to visit O'Fallon?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$30,741 GYD | G$31,786 GYD | G$35,759 GYD | G$36,178 GYD | G$37,014 GYD | G$38,478 GYD | G$42,033 GYD | G$40,151 GYD | G$40,987 GYD | G$40,151 GYD | G$41,824 GYD | G$41,824 GYD |
| Avg. temp | 0°C | 3°C | 8°C | 14°C | 20°C | 25°C | 27°C | 26°C | 22°C | 15°C | 8°C | 3°C |
Quick stats about vacation rentals that are family-friendly in O'Fallon

Total vacation rentals
Explore 60 vacation rentals in O'Fallon

Nightly prices starting at
O'Fallon vacation rentals start at G$14,638 GYD per night before taxes and fees

Verified guest reviews
Over 2,540 verified reviews to help you choose

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Rentals with dedicated workspaces
40 properties have a dedicated workspace

Wi-Fi availability
60 of O'Fallon vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across O'Fallon rentals

4.8 Average rating
O'Fallon stays are highly rated by guests—averaging 4.8 out of 5!
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- Rentals with a washer and dryer O'Fallon
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- Rentals with a patio O'Fallon
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- Family-friendly rentals St. Charles County
- Family-friendly rentals Missouri
- Family-friendly rentals United States
- Central West End
- Busch Stadium
- Six Flags St. Louis
- Enterprise Center
- Saint Louis Zoo
- City Museum
- St. Louis Aquarium at Union Station
- Missouri Botanical Garden
- Gateway Arch National Park
- Hidden Valley Ski Resort
- Castlewood State Park
- Meramec State Park
- Cathedral Basilica of Saint Louis
- The Dome at America's Center
- Saint Louis Science Center
- Washington University in St Louis
- Gateway Arch
- Missouri History Museum
- Laumeier Sculpture Park
- Saint Louis University
- Forest Park
- Fabulous Fox
- Soulard Farmers Market
- The Pageant




