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Family-friendly vacation rentals in Mesilla

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in Mesilla

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite
Guesthouse in Las Cruces
4.96 out of 5 average rating, 210 reviews

Quaint casita for 2

*Sep 2025 New bed/Aug 2024 New A/C mini split* Quiet cul-de-sac and peaceful landing spot within minutes to NMSU and Old Mesilla. Easy access to I-10 and I-25. Close to golf courses, shopping and the beauty of Las Cruces and Mesilla. Private entrance to casita, patio with dining table and a cozy bedroom, bathroom with tub/shower, WiFi, coffee station, refrigerator with small freezer, microwave. Wonderful hiking trails nearby and less than 60 minutes to White Sands National Park and ELP Airport.

Superhost
Guesthouse in Las Cruces
4.87 out of 5 average rating, 281 reviews

Studio Casita 5 mins to Farmer's mkt/dogs welcome!

We welcome you to our cozy guest house in the heart of Downtown Las Cruces. Perfect for overnights with dogs or kiddos! Close to shopping, the Farmer's Market, and centrally located to enjoy all Las Cruces has to offer. You will have a private entrance, off-street parking, and a fenced yard to yourself. There is a queen bed and a pack-n-play as requested. There is a small kitchenette with a fridge, microwave, sm hot plate, and sink and the casita is equipped with utensils and the basics for you.

Guest favorite
A room features a spacious bed dressed in white linens, complemented by a dark blue throw pillow. Natural light filters in through sheer curtains. A small table with a microwave and refrigerator is visible, along with a black rug on the floor and a fan in the corner.
Guest suite in Las Cruces
4.93 out of 5 average rating, 602 reviews

Tiny Cute Cubby in Telshor Hills, Private Entrance

The Cubby is perfect for overnight or short-term stays. Zero contact check-in and check-out. Access to central Las Cruces. Close to NMSU, Mesilla Valley Mall, major medical centers, and major event facilities. Located in Telshor Hills, a quiet neighborhood with plenty of mature trees and vegetation. Close proximity to observatory, minimal light pollution. Gorgeous views of Organ Mountains and Tortugas Mountain (A Mountain). Ten minute drive from historic Mesilla. Close to various hiking trails.

Guest favorite
The exterior of the condominium features a warm, earth-toned façade, accented by decorative arches and wrought iron details. Palm trees frame the entrance, which presents a covered portico with stylish lanterns. The structure reflects a blend of modern and traditional architectural elements.
Condo in Las Cruces
4.9 out of 5 average rating, 124 reviews

Old Mesilla Resort Style Condo

Enjoy this 2 bedroom, 2 bathroom condominium with resort amenities. The condo has all the features that will make you feel right at home. Whether you want to cook in the full kitchen, enjoy an evening by the fireplace, or catch some sun by the pool, you'll find all the comforts of home. The condo is located in a gated community, which offers access to a fitness center and pool. The condo is located in the heart of Old Mesilla, walking distance to restaurants, a coffee shop, and shopping.

Superhost
A cozy living room is depicted, featuring a comfortable dark sofa with decorative cushions. A large piece of wall art displays two figures sitting on a bench, creating a sense of connection. An antique trunk and a decorative green vase enhance the inviting space.
Earthen home in Las Cruces
4.84 out of 5 average rating, 632 reviews

Southwest Mexican Adobe Casa Historic District

This wonderful adobe home with refrigerated air is located directly in the heart of the city the Mesquite Historic District of Las Cruces. This Mexican home combines the neighborhood classic adobe style. Directly across the street is a Mexican cafe and a coffee shop. Seven minute walk to downtown which has wonderful pubs and restaurants. This home is located directly across the street from my other two casitas that are listed in Airbnb. Dog fee $10.00 which can be left on the table.

Guest favorite
A private porch area features colorful blue chairs and a grill, providing a relaxed outdoor space. A hot tub is visible to one side, and the vintage Airstream reflects sunlight with its polished exterior. String lights overhead enhance the inviting atmosphere.
Tiny home in Mesilla Park
4.93 out of 5 average rating, 239 reviews

Airstream Airdream w hot tub!

Welcome to the “Retro Retreat,” a 1968 Land Yacht infused with NM’s enchantment. This vintage stay has been lovingly curated with elements of nostalgic Americana and contemporary desert chic, featuring vintage books, games, and iconic art. This fully restored tiny stay set amidst a pecan field in the Mesilla Park district offers modern amenities including a remodeled bathroom with shower, Wi-Fi, Smart TV, a mini-split for easy heating and cooling, and a private hot tub for relaxation.

Guest favorite
The exterior of the home is shown with a gravel landscape and desert vegetation. A bright rainbow arches over the structure, which features large windows reflecting the natural light. Nearby utilities are visible along with additional structures in the background.
Shipping container in Las Cruces
4.88 out of 5 average rating, 104 reviews

@ Cosy Shipping Container Home

Modern shipping container home built with two 40-foot containers, fully furnished in a contemporary style with peaceful views and private driveway. One bedroom space, full kitchen with clothes washer & dryer, full bathroom (shower/toilet/sink), living room with sofa bed, dining table/chairs and small work desk. Adjacent private patio with pleasant views. LED lighting throughout, Wi-Fi Internet & TV, near bike path & downtown. Pet-friendly, please see House Rules for details/cost.

Top guest favorite
The entrance features a traditional adobe archway with purple wooden doors flanked by a rustic ladder. A lantern hangs above the opening, while desert vegetation is visible to one side. The backdrop includes distant mountains under a clear blue sky.
Guesthouse in Las Cruces
5 out of 5 average rating, 273 reviews

Desert Peaks Casita

This lovingly remodeled casita just fifteen minutes from downtown Las Cruces is open, spacious, and comfortably equipped for any length stay. Take in the views of the mountains, watch the birds, or relax in the hot tub under the stars. Hike to the Organ Mountains-Desert Peaks National Monument via an arroyo from the casita, take a dip in the pool, or rest in the peaceful and tastefully decorated space. It is a perfect place for a quiet getaway or as a base to explore the area.

Top guest favorite
A spacious room features a regal four-poster bed adorned with golden bedding. Antique-style lamps on either side illuminate the space, while a cozy seating area in the corner invites relaxation. Exposed wooden beams and a decorative fireplace add to the historic Southwestern charm.
Guest suite in Mesilla
4.99 out of 5 average rating, 119 reviews

Josefina's King Suite in Mesilla Plaza

Josefina's King Suite is located just off the Plaza in Historic Old Mesilla. Behind the thick adobe walls, you will find this tranquil retreat. Charmed by the ambiance of our historic Southwestern design and the Garden Greenhouse, our luxurious King Suite offers a cozy step back in time, weaving together old world charm and modern comforts like WIFI, mini fridge, AC, plush bathrobes and more. If the King is already booked, please check out our Queen Suite!

Top guest favorite
A cozy interior space features a queen bed with a bright yellow throw pillow. A kitchenette with a microwave, mini-fridge, and sink is present. Natural light filters through the windows, which are adorned with blue curtains. A small table and chairs complement the room's design.
Guesthouse in Las Cruces
4.97 out of 5 average rating, 337 reviews

Cozy Casita w/private patio near Old Mesilla

This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Top guest favorite
A modern interior features a wooden dining table with two black chairs, accompanied by a decorative bowl. A wall hanging adds texture, while a metal rack displays clothing and a woven basket. Natural light filters through a nearby window, highlighting the clean lines of the space.
Guesthouse in Las Cruces
4.99 out of 5 average rating, 197 reviews

Yucca Casita in Historic Mesilla

Mesilla STR Permit #0830 We have created a sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

Top guest favorite
A charming casita features a turquoise door and a light exterior, framed by subtle landscaping. The sky is filled with vibrant orange and yellow hues as the sun sets, creating a striking contrast against the white walls and windows.
Guesthouse in Las Cruces
4.99 out of 5 average rating, 200 reviews

Cozy Casita De Mesilla

Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.

Popular amenities for Mesilla family-friendly rentals

When is the best time to visit Mesilla?

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Avg. priceG$26,778 GYDG$26,151 GYDG$26,151 GYDG$24,268 GYDG$26,151 GYDG$26,151 GYDG$24,059 GYDG$24,477 GYDG$21,757 GYDG$26,151 GYDG$26,151 GYDG$26,151 GYD
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Quick stats about vacation rentals that are family-friendly in Mesilla

  • Total vacation rentals

    Explore 40 vacation rentals in Mesilla

  • Nightly prices starting at

    Mesilla vacation rentals start at G$16,736 GYD per night before taxes and fees

  • Verified guest reviews

    Over 2,520 verified reviews to help you choose

  • Pet-friendly vacation rentals

    Find 20 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    20 properties have a dedicated workspace

  • Wi-Fi availability

    40 of Mesilla vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mesilla rentals

  • 4.9 Average rating

    Mesilla stays are highly rated by guests—averaging 4.9 out of 5!