
Family-friendly vacation rentals in Mesilla
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in Mesilla
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

Quaint casita for 2
*Sep 2025 New bed/Aug 2024 New A/C mini split* Quiet cul-de-sac and peaceful landing spot within minutes to NMSU and Old Mesilla. Easy access to I-10 and I-25. Close to golf courses, shopping and the beauty of Las Cruces and Mesilla. Private entrance to casita, patio with dining table and a cozy bedroom, bathroom with tub/shower, WiFi, coffee station, refrigerator with small freezer, microwave. Wonderful hiking trails nearby and less than 60 minutes to White Sands National Park and ELP Airport.

Studio Casita 5 mins to Farmer's mkt/dogs welcome!
We welcome you to our cozy guest house in the heart of Downtown Las Cruces. Perfect for overnights with dogs or kiddos! Close to shopping, the Farmer's Market, and centrally located to enjoy all Las Cruces has to offer. You will have a private entrance, off-street parking, and a fenced yard to yourself. There is a queen bed and a pack-n-play as requested. There is a small kitchenette with a fridge, microwave, sm hot plate, and sink and the casita is equipped with utensils and the basics for you.

Tiny Cute Cubby in Telshor Hills, Private Entrance
The Cubby is perfect for overnight or short-term stays. Zero contact check-in and check-out. Access to central Las Cruces. Close to NMSU, Mesilla Valley Mall, major medical centers, and major event facilities. Located in Telshor Hills, a quiet neighborhood with plenty of mature trees and vegetation. Close proximity to observatory, minimal light pollution. Gorgeous views of Organ Mountains and Tortugas Mountain (A Mountain). Ten minute drive from historic Mesilla. Close to various hiking trails.

Old Mesilla Resort Style Condo
Enjoy this 2 bedroom, 2 bathroom condominium with resort amenities. The condo has all the features that will make you feel right at home. Whether you want to cook in the full kitchen, enjoy an evening by the fireplace, or catch some sun by the pool, you'll find all the comforts of home. The condo is located in a gated community, which offers access to a fitness center and pool. The condo is located in the heart of Old Mesilla, walking distance to restaurants, a coffee shop, and shopping.

Southwest Mexican Adobe Casa Historic District
This wonderful adobe home with refrigerated air is located directly in the heart of the city the Mesquite Historic District of Las Cruces. This Mexican home combines the neighborhood classic adobe style. Directly across the street is a Mexican cafe and a coffee shop. Seven minute walk to downtown which has wonderful pubs and restaurants. This home is located directly across the street from my other two casitas that are listed in Airbnb. Dog fee $10.00 which can be left on the table.

Airstream Airdream w hot tub!
Welcome to the “Retro Retreat,” a 1968 Land Yacht infused with NM’s enchantment. This vintage stay has been lovingly curated with elements of nostalgic Americana and contemporary desert chic, featuring vintage books, games, and iconic art. This fully restored tiny stay set amidst a pecan field in the Mesilla Park district offers modern amenities including a remodeled bathroom with shower, Wi-Fi, Smart TV, a mini-split for easy heating and cooling, and a private hot tub for relaxation.

@ Cosy Shipping Container Home
Modern shipping container home built with two 40-foot containers, fully furnished in a contemporary style with peaceful views and private driveway. One bedroom space, full kitchen with clothes washer & dryer, full bathroom (shower/toilet/sink), living room with sofa bed, dining table/chairs and small work desk. Adjacent private patio with pleasant views. LED lighting throughout, Wi-Fi Internet & TV, near bike path & downtown. Pet-friendly, please see House Rules for details/cost.

Desert Peaks Casita
This lovingly remodeled casita just fifteen minutes from downtown Las Cruces is open, spacious, and comfortably equipped for any length stay. Take in the views of the mountains, watch the birds, or relax in the hot tub under the stars. Hike to the Organ Mountains-Desert Peaks National Monument via an arroyo from the casita, take a dip in the pool, or rest in the peaceful and tastefully decorated space. It is a perfect place for a quiet getaway or as a base to explore the area.

Josefina's King Suite in Mesilla Plaza
Josefina's King Suite is located just off the Plaza in Historic Old Mesilla. Behind the thick adobe walls, you will find this tranquil retreat. Charmed by the ambiance of our historic Southwestern design and the Garden Greenhouse, our luxurious King Suite offers a cozy step back in time, weaving together old world charm and modern comforts like WIFI, mini fridge, AC, plush bathrobes and more. If the King is already booked, please check out our Queen Suite!

Cozy Casita w/private patio near Old Mesilla
This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Yucca Casita in Historic Mesilla
Mesilla STR Permit #0830 We have created a sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

Cozy Casita De Mesilla
Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.
Popular amenities for Mesilla family-friendly rentals
Family-friendly home rentals with a hot tub

Modern Hidden Gem- HOT TUB & Organ Mtn Views/Patio

Hidden Las Cruces Retreat

Hadley House 1 Bed/ 1 Bath Hot Tub 5 min downtown

Hot Tub Getaway

Cozy downtown adobe home with hot tub and sauna

Tuscan Villa Outdoor Living, Jacuzzi & Gym

Home in Las Cruces Casa de Flores Near NMSU

Pecan Palace – Luxe 4BR w/ Hot Tub, Game Room & EV
Family- and pet-friendly home rentals

"Casa de Maíz" centrally located - close to NMSU

Artistic Escape

Casa Elena Adobe casita in historic Mesilla

New Modern/Cozy Spacious Home

NMSU Casitas “C" Pet Friendly!

1 bedroom private studio with kitchenette n patio!

Amazing Historical Bungalow-NMSU, Mesilla

Lus Solar Tranquila gated community/golf course
Family-friendly home rentals with a pool

Luxury Home- Pool, Views, Early Check in

Nature Retreat 12-min from Downtown (with pool)

Pet Friendly Luxury Retreat W/ Heated Pool & Spa

Cozy Casita Blanca at Hacienda de Las Cruces

Sancho's Condo De Mesilla

95° Heated Saltwater Pool | Desert Views | Pets OK

Desert Oasis with Pool

The Loft
When is the best time to visit Mesilla?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$26,778 GYD | G$26,151 GYD | G$26,151 GYD | G$24,268 GYD | G$26,151 GYD | G$26,151 GYD | G$24,059 GYD | G$24,477 GYD | G$21,757 GYD | G$26,151 GYD | G$26,151 GYD | G$26,151 GYD |
| Avg. temp | 4°C | 7°C | 10°C | 14°C | 19°C | 25°C | 27°C | 25°C | 22°C | 15°C | 9°C | 4°C |
Quick stats about vacation rentals that are family-friendly in Mesilla

Total vacation rentals
Explore 40 vacation rentals in Mesilla

Nightly prices starting at
Mesilla vacation rentals start at G$16,736 GYD per night before taxes and fees

Verified guest reviews
Over 2,520 verified reviews to help you choose

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wi-Fi availability
40 of Mesilla vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mesilla rentals

4.9 Average rating
Mesilla stays are highly rated by guests—averaging 4.9 out of 5!
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