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Family-friendly vacation rentals in Mesilla

Find and book unique family-friendly homes on Airbnb

Quick stats about vacation rentals that are family-friendly in Mesilla

  • Total vacation rentals

    Explore 40 vacation rentals in Mesilla

  • Nightly prices starting at

    Mesilla vacation rentals start at G$16,723 GYD per night before taxes and fees

  • Verified guest reviews

    Over 2,390 verified reviews to help you choose

  • Pet-friendly vacation rentals

    Find 20 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    40 of Mesilla vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mesilla rentals

  • 4.9 Average rating

    Mesilla stays are highly rated by guests—averaging 4.9 out of 5!

Top-rated family-friendly rentals in Mesilla

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite
The living area showcases rich wood flooring, a vibrant patterned sofa, and a dark wooden coffee table. A dining area with a round table and four chairs is visible. The walls feature deep maroon accents and framed artwork, creating a cozy and inviting layout.
Home in Mesilla Park
4.94 out of 5 average rating, 260 reviews

Charming 1930 home near NMSU/ Mesilla

Sunny two bedroom one bath house on a quiet tree lined street in Mesilla Park. Enjoy this peaceful retreat close to everything. Conveniently located near the Mesilla Plaza, NMSU, and the Convention Center. Refrigerated air set up on the Nest system. The house has internet access. The wood floors, sash windows and front screen porch give this house the character we fell in love with. We've tried to decorate it to feel like home, and provide all the amenities you might need while you're staying.

Guest favorite
Guesthouse in Las Cruces
4.95 out of 5 average rating, 168 reviews

1 king bd with big fenced back yard pets welcome

Casita La Pacana is nestled in the middle of town surrounded by old pecan trees. Feels like the country but is in the middle of town. 1 bedroom, completely renovated casita that has 1 kind bed, a large living room, streaming TVs in both living room and bedroom, full kitchen including a dishwasher and washer/dryer, hardwood floors, authentic Talavera tile, large shower with a bench seat, huge back yard, and ample parking! This little casita has everything to be your home away from home.

Guest favorite
The historic adobe home is adorned with natural tones and rustic architecture. A welcoming entrance is framed by a decorative wrought iron gate, alongside a gravel pathway leading to the front door. Lush greenery and native plants enhance the inviting exterior.
Home in Las Cruces
4.94 out of 5 average rating, 247 reviews

Historic Adobe Home- Libélula (Dragonfly)

Adobe Libélula (Dragonfly) Historic pueblo-style adobe home & property, complimented with front & rear patios, gazebo, gardens & off-street gated parking. Lovingly renovated 1930 Adobe. Live in the birthplace of Las Cruces. A ​5-minute casual stroll to explore and enjoy the origins of Las Cruces, neighborhood restaurants & coffee shops in the Mesquite Historic District, AND museums, shops, a street market off Main St. Las Cruces. Traditional Mexican Décor, Central A/C, WiFi, Smart TV.

Top guest favorite
A spacious room features traditional Southwestern adobe walls and exposed wooden beams. A four-poster bed is adorned with a colorful quilt. An elegant sitting area includes vintage chairs and a decorative mirror, while natural light filters through multiple windows, creating a warm ambiance.
Guest suite in Mesilla
4.96 out of 5 average rating, 183 reviews

Josefina's Queen Suite in Mesilla Plaza.

Josefina's Queen Suite is located just off the Plaza in Historic Old Mesilla. Behind the thick adobe walls, you will find this tranquil retreat. Charmed by the ambiance of our historic Southwestern design and the Garden Greenhouse, our luxurious Queen Suite offers a cozy step back in time, weaving together old world charm and modern comforts like WIFI, mini fridge, Smart TV, AC, plush bathrobes and more. If the Queen suite is already booked, please check out our King Suite!

Top guest favorite
The exterior of the guesthouse features a welcoming entrance with a turquoise door framed by two wooden columns. A small seating area with two chairs is positioned on the porch, accompanied by potted plants and a tiled floor. The sky above displays a gentle blend of blue and white hues.
Guesthouse in Mesilla
4.97 out of 5 average rating, 395 reviews

Getaway Guesthouse in Historic Mesilla

Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

Top guest favorite
A tranquil sleeping area features a spacious bed adorned with decorative pillows and a handwoven wall hanging above. Soft lighting from an ornate chandelier complements the adobe walls, while a rustic table and chairs anchor the inviting space.
Guesthouse in Las Cruces
4.97 out of 5 average rating, 360 reviews

Clara's Nest - The Gem of Hacienda de Las Cruces

Clara’s Nest is in a 1880's adobe compound with its own private entry, courtyard, original stone floors, handcrafted beams, hand-painted bird & flower motif throughout. The suite features a king bed, cozy loveseat & ottoman in the sleeping area, dining table & 4 chairs, kitchenette with micro, fridge, coffee & tea bar, a separate living room with sofa, TV, private bath. Outer space includes: covered patio, backyard, pool and hot tub area (heated upon request) No stove.

Superhost
A bright and airy living space features a blend of modern and vintage elements. A dining table is elegantly set with vibrant decor, while yellow accent chairs provide a pop of color. A cozy blue sofa is positioned nearby, alongside a window adorned with cheerful curtains.
Home in Mesilla Park
4.93 out of 5 average rating, 378 reviews

One bedroom casita in Mesilla Park with hot tub

This unique place has an ambiance all its own. Located a few minute drive from historic old Mesilla and walking distance to a local coffee shop, Mexican restaurant, and a pizza restaurant. Mesilla plaza, and bars are only a few minutes drive away. The building has stainless steel new appliances and dual refrigerated air mini splits, one in the living room, and one in the bedroom. Please note there is a train that occasionally travels near the neighborhood.

Top guest favorite
A spacious outdoor area showcases a desert landscape with gravel and low-lying plants. A large round table is accompanied by a bright red umbrella, offering shade. The casita's entrance features a patio with seating and a welcoming purple trim, enhancing the inviting exterior.
Home in Mesilla
4.98 out of 5 average rating, 201 reviews

Charming Adobe One Block from the Mesilla Plaza

Beautiful, private casita built in the 1930's one block from the plaza. Historic charm with modern conveniences. Perfect for quiet retreat. Fenced flagstone patio in back yard fully equipped with gas grill, outdoor fireplace, outdoor dining area and french doors opening from the house. Large front yard fully enclosed. Full front porch creates shade. This house is peaceful but just steps from the fiestas and activities on the historical Mesilla Plaza.

Top guest favorite
An adobe-style home is displayed, featuring a gravel pathway leading to an entrance framed by wooden gates. Two turquoise chairs sit beside a small table under a budding tree. Planted flowers in bright pots add color to the exterior, enhancing the welcoming appearance.
Home in Mesilla
4.98 out of 5 average rating, 174 reviews

Sombra Del Valle in Historic Mesilla.

Sombra Del Valle is a beautiful home located in a quiet neighborhood and within 5 minute walking distance to the historic Mesilla plaza and 2 minute walking distance to a Brewery and restaurant and approximately 5 minute drive to NMSU. The home is comfortable and spacious; great for family trips, honeymoons, or just a fun getaway. There is free guest private parking. Once you stay here you will want to come back; it’s a home away from home.

Guest favorite
A cozy interior space features a queen bed with a bright yellow throw pillow. A kitchenette with a microwave, mini-fridge, and sink is present. Natural light filters through the windows, which are adorned with blue curtains. A small table and chairs complement the room's design.
Guesthouse in Las Cruces
4.97 out of 5 average rating, 380 reviews

Cozy Casita w/private patio near Old Mesilla

This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Top guest favorite
A modern interior features a wooden dining table with two black chairs, accompanied by a decorative bowl. A wall hanging adds texture, while a metal rack displays clothing and a woven basket. Natural light filters through a nearby window, highlighting the clean lines of the space.
Guesthouse in Mesilla
4.99 out of 5 average rating, 220 reviews

Yucca Casita in Historic Mesilla

Mesilla STR Permit #0830 We have created a sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

Top guest favorite
A charming casita features a turquoise door and a light exterior, framed by subtle landscaping. The sky is filled with vibrant orange and yellow hues as the sun sets, creating a striking contrast against the white walls and windows.
Guesthouse in Mesilla
4.99 out of 5 average rating, 249 reviews

Cozy Casita De Mesilla (Mesilla Cottage)

Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.

Popular amenities for Mesilla family-friendly rentals

When is the best time to visit Mesilla?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$26,757 GYDG$28,220 GYDG$26,130 GYDG$24,248 GYDG$26,130 GYDG$26,130 GYDG$24,039 GYDG$24,457 GYDG$21,740 GYDG$25,293 GYDG$26,130 GYDG$26,339 GYD
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