
Family-friendly vacation rentals in Mesilla
Find and book unique family-friendly homes on Airbnb
Quick stats about vacation rentals that are family-friendly in Mesilla

Total vacation rentals
Explore 40 vacation rentals in Mesilla

Nightly prices starting at
Mesilla vacation rentals start at G$16,723 GYD per night before taxes and fees

Verified guest reviews
Over 2,390 verified reviews to help you choose

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
40 of Mesilla vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mesilla rentals

4.9 Average rating
Mesilla stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated family-friendly rentals in Mesilla
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

Charming 1930 home near NMSU/ Mesilla
Sunny two bedroom one bath house on a quiet tree lined street in Mesilla Park. Enjoy this peaceful retreat close to everything. Conveniently located near the Mesilla Plaza, NMSU, and the Convention Center. Refrigerated air set up on the Nest system. The house has internet access. The wood floors, sash windows and front screen porch give this house the character we fell in love with. We've tried to decorate it to feel like home, and provide all the amenities you might need while you're staying.

1 king bd with big fenced back yard pets welcome
Casita La Pacana is nestled in the middle of town surrounded by old pecan trees. Feels like the country but is in the middle of town. 1 bedroom, completely renovated casita that has 1 kind bed, a large living room, streaming TVs in both living room and bedroom, full kitchen including a dishwasher and washer/dryer, hardwood floors, authentic Talavera tile, large shower with a bench seat, huge back yard, and ample parking! This little casita has everything to be your home away from home.

Historic Adobe Home- Libélula (Dragonfly)
Adobe Libélula (Dragonfly) Historic pueblo-style adobe home & property, complimented with front & rear patios, gazebo, gardens & off-street gated parking. Lovingly renovated 1930 Adobe. Live in the birthplace of Las Cruces. A 5-minute casual stroll to explore and enjoy the origins of Las Cruces, neighborhood restaurants & coffee shops in the Mesquite Historic District, AND museums, shops, a street market off Main St. Las Cruces. Traditional Mexican Décor, Central A/C, WiFi, Smart TV.

Josefina's Queen Suite in Mesilla Plaza.
Josefina's Queen Suite is located just off the Plaza in Historic Old Mesilla. Behind the thick adobe walls, you will find this tranquil retreat. Charmed by the ambiance of our historic Southwestern design and the Garden Greenhouse, our luxurious Queen Suite offers a cozy step back in time, weaving together old world charm and modern comforts like WIFI, mini fridge, Smart TV, AC, plush bathrobes and more. If the Queen suite is already booked, please check out our King Suite!

Getaway Guesthouse in Historic Mesilla
Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

Clara's Nest - The Gem of Hacienda de Las Cruces
Clara’s Nest is in a 1880's adobe compound with its own private entry, courtyard, original stone floors, handcrafted beams, hand-painted bird & flower motif throughout. The suite features a king bed, cozy loveseat & ottoman in the sleeping area, dining table & 4 chairs, kitchenette with micro, fridge, coffee & tea bar, a separate living room with sofa, TV, private bath. Outer space includes: covered patio, backyard, pool and hot tub area (heated upon request) No stove.

One bedroom casita in Mesilla Park with hot tub
This unique place has an ambiance all its own. Located a few minute drive from historic old Mesilla and walking distance to a local coffee shop, Mexican restaurant, and a pizza restaurant. Mesilla plaza, and bars are only a few minutes drive away. The building has stainless steel new appliances and dual refrigerated air mini splits, one in the living room, and one in the bedroom. Please note there is a train that occasionally travels near the neighborhood.

Charming Adobe One Block from the Mesilla Plaza
Beautiful, private casita built in the 1930's one block from the plaza. Historic charm with modern conveniences. Perfect for quiet retreat. Fenced flagstone patio in back yard fully equipped with gas grill, outdoor fireplace, outdoor dining area and french doors opening from the house. Large front yard fully enclosed. Full front porch creates shade. This house is peaceful but just steps from the fiestas and activities on the historical Mesilla Plaza.

Sombra Del Valle in Historic Mesilla.
Sombra Del Valle is a beautiful home located in a quiet neighborhood and within 5 minute walking distance to the historic Mesilla plaza and 2 minute walking distance to a Brewery and restaurant and approximately 5 minute drive to NMSU. The home is comfortable and spacious; great for family trips, honeymoons, or just a fun getaway. There is free guest private parking. Once you stay here you will want to come back; it’s a home away from home.

Cozy Casita w/private patio near Old Mesilla
This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Yucca Casita in Historic Mesilla
Mesilla STR Permit #0830 We have created a sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

Cozy Casita De Mesilla (Mesilla Cottage)
Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.
Popular amenities for Mesilla family-friendly rentals
Family-friendly home rentals with a hot tub

Modern Hidden Gem- HOT TUB & Organ Mtn Views/Patio

Hadley House 1 Bed/ 1 Bath Hot Tub 5 min downtown

Private Oasis Near Old Mesilla with Pool/Jacuzzi!

Home in Las Cruces Casa de Flores (Flower House) Near NMSU

Apache’s Retreat w/ HOT TUB & Pool table

Pecan Palace – Luxe 4BR w/ Hot Tub, Game Room & EV

Vacation Home

Serene desert oasis w/ hot tub and mountain view!
Family- and pet-friendly home rentals

Cul-de-sac Condo

Artistic Escape

Casa Mesilla

New Home in Beautiful Golf Course Community

The Stranded Time Traveler; a timeless experience!

Haciendas de Horacio 3 bedrooms w/2 king beds.

Southwest Mexican Adobe Casa Historic District

El Studio Steps from Historic Mesilla Plaza & Park
Family-friendly home rentals with a pool

Luxury Home- Pool, Views, Early Check in

[Pool open] Nature Retreat 12-min from Downtown

Inviting Las Cruces Condo < 1 Mi to Mesilla Plaza!

Pet Friendly Luxury Retreat W/ Heated Pool & Spa

Sancho's Condo in Mesilla

95° Heated Saltwater Pool | Desert Views | Pets OK

Desert Peaks Casita

Desert Oasis with Pool
When is the best time to visit Mesilla?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$26,757 GYD | G$28,220 GYD | G$26,130 GYD | G$24,248 GYD | G$26,130 GYD | G$26,130 GYD | G$24,039 GYD | G$24,457 GYD | G$21,740 GYD | G$25,293 GYD | G$26,130 GYD | G$26,339 GYD |
| Avg. temp | 4°C | 7°C | 10°C | 14°C | 19°C | 25°C | 27°C | 25°C | 22°C | 15°C | 9°C | 4°C |
Destinations to explore
- Tucson Vacation rentals
- Albuquerque Vacation rentals
- El Paso Vacation rentals
- Chihuahua Vacation rentals
- Ciudad Juárez Vacation rentals
- Santa Fe Vacation rentals
- Ruidoso Vacation rentals
- Las Cruces Vacation rentals
- Gilbert Vacation rentals
- Midland Vacation rentals
- Nogales Vacation rentals
- Carlsbad Vacation rentals
- Pet-friendly rentals Mesilla
- Rentals with a washer and dryer Mesilla
- Rentals with a fire pit Mesilla
- Rentals with outdoor seating Mesilla
- Rentals with pools Mesilla
- House rentals Mesilla
- Rentals with a patio Mesilla
- Rentals with a fireplace Mesilla
- Family-friendly rentals Doña Ana County
- Family-friendly rentals New Mexico
- Family-friendly rentals United States
- White Sands National Park
- Sun Bowl Stadium
- Wet 'N' Wild Waterworld
- Franklin Mountains State Park
- La Rodadora Espacio Interactivo
- El Paso Zoo
- El Paso Chihuahuas
- El Paso Museum of Art
- San Jacinto Plaza
- New Mexico Farm & Ranch Heritage Museum
- Sunland Park Racetrack & Casino
- Farmers And Crafts Market of Las Cruces
- Dripping Springs Natural Area
- Western Playland
- Southwest University Park
- Plaza Theatre
- Memorial Park
- Casa de Juan Gabriel
- Mesilla Plaza
- Chamizal National Memorial
- Museo de la Revolución en la Frontera





