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Family-friendly vacation rentals in Mesilla

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in Mesilla

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Superhost
A cozy living room is depicted, featuring a comfortable dark sofa with decorative cushions. A large piece of wall art displays two figures sitting on a bench, creating a sense of connection. An antique trunk and a decorative green vase enhance the inviting space.
Earthen home in Las Cruces
4.84 out of 5 average rating, 678 reviews

Southwest Mexican Adobe Casa Historic District

This wonderful adobe home with refrigerated air is located directly in the heart of the city the Mesquite Historic District of Las Cruces. This Mexican home combines the neighborhood classic adobe style. Directly across the street is a Mexican cafe and a coffee shop. Seven minute walk to downtown which has wonderful pubs and restaurants. This home is located directly across the street from my other two casitas that are listed in Airbnb. Dog fee $10.00 which can be left on the table.

Top guest favorite
The exterior of the guesthouse features a welcoming entrance with a turquoise door framed by two wooden columns. A small seating area with two chairs is positioned on the porch, accompanied by potted plants and a tiled floor. The sky above displays a gentle blend of blue and white hues.
Guesthouse in Mesilla
4.97 out of 5 average rating, 395 reviews

Getaway Guesthouse in Historic Mesilla

Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

Top guest favorite
A bright interior features a queen bed adorned with geometric patterned bedding. Adjacent to the bed, two armchairs offer comfortable seating. A small loft area with a twin bed is visible overhead. A mirror and lamps provide additional lighting in the room.
Tiny home in La Mesa
4.97 out of 5 average rating, 224 reviews

Little House with Private Patio and Hot Tub

Our guesthouse is located on historic Highway 28, also known as the Don Juan de Onate Trail, which connects El Paso and Las Cruces. It is one of the area's most scenic routes. You can find breweries, multiple wineries, and the famous Chopes restaurant and bar along the route. The highlight of the 10-mile drive from our little house in San Miguel to historic Mesilla takes you through unique canopies of pecan trees, in the largest pecan-producing county in the nation.

Guest favorite
Home in Las Cruces
4.9 out of 5 average rating, 145 reviews

Pecan Palace – Luxe 4BR w/ Hot Tub, Game Room & EV

Pecan Palace: luxe 4-BR near NMSU & White Sands. Tucked by pecan farms, this new retreat blends comfort + fun. Perfect for families, work trips, extended stays. ☞ EV charger ☞ Backyard hot tub under pergola ☞ Climate-controlled game lounge with pool table ☞ Foosball ☞ Poker ☞ Pac-Man ☞ Fully equipped chef's kitchen ☞ Plush bedrooms with blackout curtains ☞ Prime spot—1.5 mi to NMSU, Interstate I-10, dining & shopping ☞ Easy access to White Sands NP and downtown

Top guest favorite
Two colorful planters holding purple cactus are positioned beside a large window on the exterior wall of the adobe home. The warm-toned stucco walls and terra-cotta tiled flooring add to the inviting appearance of the entryway, which is framed by traditional wooden beams above.
Home in Mesilla
4.96 out of 5 average rating, 138 reviews

Mesilla 1869 Adobe 2 blocks from plaza

I purchased this beautiful home built circa 1869 all Adobe in May 2019 and I want to share it with you! I am living in this home as one of my primary residences but I’m traveling the world and will make it available so you can also enjoy it. Authentic wood beams “vigas” and “latillas”, original kitchen wood floor, painted cement floors (by the previous artist owner), 3 foot thick adobe interior walls. Just steps to the Mesilla Plaza, shops, restaurants!

Superhost
A bright and airy living space features a blend of modern and vintage elements. A dining table is elegantly set with vibrant decor, while yellow accent chairs provide a pop of color. A cozy blue sofa is positioned nearby, alongside a window adorned with cheerful curtains.
Home in Mesilla Park
4.93 out of 5 average rating, 376 reviews

One bedroom casita in Mesilla Park with hot tub

This unique place has an ambiance all its own. Located a few minute drive from historic old Mesilla and walking distance to a local coffee shop, Mexican restaurant, and a pizza restaurant. Mesilla plaza, and bars are only a few minutes drive away. The building has stainless steel new appliances and dual refrigerated air mini splits, one in the living room, and one in the bedroom. Please note there is a train that occasionally travels near the neighborhood.

Top guest favorite
A spacious room features a regal four-poster bed adorned with golden bedding. Antique-style lamps on either side illuminate the space, while a cozy seating area in the corner invites relaxation. Exposed wooden beams and a decorative fireplace add to the historic Southwestern charm.
Guest suite in Mesilla
4.99 out of 5 average rating, 139 reviews

Josefina's King Suite in Mesilla Plaza.

Josefina's King Suite is located just off the Plaza in Historic Old Mesilla. Behind the thick adobe walls, you will find this tranquil retreat. Charmed by the ambiance of our historic Southwestern design and the Garden Greenhouse, our luxurious King Suite offers a cozy step back in time, weaving together old world charm and modern comforts like WIFI, mini fridge, AC, plush bathrobes and more. If the King is already booked, please check out our Queen Suite!

Top guest favorite
A spacious outdoor area showcases a desert landscape with gravel and low-lying plants. A large round table is accompanied by a bright red umbrella, offering shade. The casita's entrance features a patio with seating and a welcoming purple trim, enhancing the inviting exterior.
Home in Mesilla
4.98 out of 5 average rating, 201 reviews

Charming Adobe One Block from the Mesilla Plaza

Beautiful, private casita built in the 1930's one block from the plaza. Historic charm with modern conveniences. Perfect for quiet retreat. Fenced flagstone patio in back yard fully equipped with gas grill, outdoor fireplace, outdoor dining area and french doors opening from the house. Large front yard fully enclosed. Full front porch creates shade. This house is peaceful but just steps from the fiestas and activities on the historical Mesilla Plaza.

Superhost
The exterior of a recently renovated tiny home features a modern design with a combination of beige and orange walls. A welcoming entrance is flanked by two planters, while a stone pathway leads to the door. Lush green grass enhances the outdoor space.
Tiny home in Las Cruces
4.92 out of 5 average rating, 243 reviews

Modern New Mexico Loft in the heart of Las Cruces.

Recently renovated tiny home with a loft-style bedroom. Many unique features will greet you in this very unusual space for Las Cruces. Downstairs there is a living room with a queen pull-out couch and a renovated kitchen that has everything you will need except an oven. Full 4 burner cooktop, microwave, full-sized fridge, and an eating bar. There is a small desk area for working, a shower bath (which is downstairs ), and a wonderful small outdoor space.

Top guest favorite
An adobe-style home is displayed, featuring a gravel pathway leading to an entrance framed by wooden gates. Two turquoise chairs sit beside a small table under a budding tree. Planted flowers in bright pots add color to the exterior, enhancing the welcoming appearance.
Home in Mesilla
4.98 out of 5 average rating, 174 reviews

Sombra Del Valle in Historic Mesilla.

Sombra Del Valle is a beautiful home located in a quiet neighborhood and within 5 minute walking distance to the historic Mesilla plaza and 2 minute walking distance to a Brewery and restaurant and approximately 5 minute drive to NMSU. The home is comfortable and spacious; great for family trips, honeymoons, or just a fun getaway. There is free guest private parking. Once you stay here you will want to come back; it’s a home away from home.

Top guest favorite
A cozy interior space features a queen bed with a bright yellow throw pillow. A kitchenette with a microwave, mini-fridge, and sink is present. Natural light filters through the windows, which are adorned with blue curtains. A small table and chairs complement the room's design.
Guesthouse in Las Cruces
4.97 out of 5 average rating, 377 reviews

Cozy Casita w/private patio near Old Mesilla

This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Top guest favorite
A modern interior features a wooden dining table with two black chairs, accompanied by a decorative bowl. A wall hanging adds texture, while a metal rack displays clothing and a woven basket. Natural light filters through a nearby window, highlighting the clean lines of the space.
Guesthouse in Mesilla
4.99 out of 5 average rating, 220 reviews

Yucca Casita in Historic Mesilla

Mesilla STR Permit #0830 We have created a sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

Popular amenities for Mesilla family-friendly rentals

When is the best time to visit Mesilla?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$26,788 GYDG$28,253 GYDG$26,160 GYDG$24,277 GYDG$26,160 GYDG$26,160 GYDG$24,068 GYDG$24,486 GYDG$21,765 GYDG$25,323 GYDG$26,160 GYDG$26,370 GYD
Avg. temp4°C7°C10°C14°C19°C25°C27°C25°C22°C15°C9°C4°C

Quick stats about vacation rentals that are family-friendly in Mesilla

  • Total vacation rentals

    Explore 40 vacation rentals in Mesilla

  • Nightly prices starting at

    Mesilla vacation rentals start at G$16,743 GYD per night before taxes and fees

  • Verified guest reviews

    Over 2,390 verified reviews to help you choose

  • Pet-friendly vacation rentals

    Find 20 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    40 of Mesilla vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mesilla rentals

  • 4.9 Average rating

    Mesilla stays are highly rated by guests—averaging 4.9 out of 5!