Some info has been automatically translated. Show original language

Vacation rentals in Doña Ana County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Doña Ana County

Guests agree: these stays are highly rated for location, cleanliness, and more.

%{current} / %{total}1 / 1
Top guest favorite
Guesthouse in Las Cruces
4.96 out of 5 average rating, 219 reviews

Quaint casita for 2

*Sep 2025 New bed/Aug 2024 New A/C mini split* Quiet cul-de-sac and peaceful landing spot within minutes to NMSU and Old Mesilla. Easy access to I-10 and I-25. Close to golf courses, shopping and the beauty of Las Cruces and Mesilla. Private entrance to casita, patio with dining table and a cozy bedroom, bathroom with tub/shower, WiFi, coffee station, refrigerator with small freezer, microwave. Wonderful hiking trails nearby and less than 60 minutes to White Sands National Park and ELP Airport.

Guest favorite
A room features a spacious bed dressed in white linens, complemented by a dark blue throw pillow. Natural light filters in through sheer curtains. A small table with a microwave and refrigerator is visible, along with a black rug on the floor and a fan in the corner.
Guest suite in Las Cruces
4.93 out of 5 average rating, 610 reviews

Tiny Cute Cubby in Telshor Hills, Private Entrance

The Cubby is perfect for overnight or short-term stays. Zero contact check-in and check-out. Access to central Las Cruces. Close to NMSU, Mesilla Valley Mall, major medical centers, and major event facilities. Located in Telshor Hills, a quiet neighborhood with plenty of mature trees and vegetation. Close proximity to observatory, minimal light pollution. Gorgeous views of Organ Mountains and Tortugas Mountain (A Mountain). Ten minute drive from historic Mesilla. Close to various hiking trails.

Top guest favorite
An outdoor seating area is highlighted by four Adirondack chairs arranged around a glowing gas fire pit. A stone wall forms the background, while a dining set is visible in the distance, with soft evening light creating a serene atmosphere.
Home in Las Cruces
4.96 out of 5 average rating, 140 reviews

Luxury Southwest Retreat

Our home provides comfort, relaxation, and convenience in an invitingly decorated setting. Three rooms offer various sleeping arrangements to meet all of your needs. Choose from a king, queen, or twin beds. Fully equipped and thoughtfully appointed kitchen provides for all of your meal needs. Luxurious backyard with Adirondack chairs, gas fire pit, porch rocking chairs, and outdoor dining set allow for relaxing and socializing. Washer & dryer available, detergent and fabric softener provided.

Top guest favorite
The bedroom features a comfortable bed with a decorative quilt and coordinated pillows. Two bedside lamps cast a gentle glow. A tray sits on the bed, and modern green stools are positioned at the foot of the bed. Dark curtains frame the window, adding privacy.
Guest suite in Las Cruces
4.92 out of 5 average rating, 236 reviews

Cozy,Clean,Contemporary Casita in Alameda District

Welcome to the perfect blend of Location, Comfort and Hospitality. Perfect for couples,business travelers and solo adventurers. Upon arrival you will find a sparkling clean cozy casita with small refrigerator,microwave and complimentary snacks for all guests. The room is contemporary, clean and comfortable and is located in the Alameda District of Las Cruces only a block from Breakfast hotspot “Bite of Belgium”. Casita Armijo is also walking distance from the Farmers Market and Downtown Mall.

Top guest favorite
A cozy studio layout displays a comfortable bed with decorative pillows. A kitchenette is visible with storage for utensils and appliances, including a mini fridge and microwave. Warm yellow walls complement the rustic decor, enhancing the inviting ambiance of the space.
Apartment in Las Cruces
4.97 out of 5 average rating, 310 reviews

Casita on the Camino Real.

Cozy 260 sq. ft. studio apartment that can accommodate two adults Comfortable queen bed Large closet Kitchenette includes mini fridge, microwave, toaster oven, crock pot, rice cooker, French press, bar sink, cooking utensils and complete dinner service Full bath with tub Small dining table and chairs inside Wi-Fi Radio clock & USB ports Wall unit that is both AC and heat Small outside sitting area with seating and small outdoor kitchen with grill Off street parking Coded door entrance

Top guest favorite
The entrance features a traditional adobe archway with purple wooden doors flanked by a rustic ladder. A lantern hangs above the opening, while desert vegetation is visible to one side. The backdrop includes distant mountains under a clear blue sky.
Guesthouse in Las Cruces
5 out of 5 average rating, 276 reviews

Desert Peaks Casita

This lovingly remodeled casita just fifteen minutes from downtown Las Cruces is open, spacious, and comfortably equipped for any length stay. Take in the views of the mountains, watch the birds, or relax in the hot tub under the stars. Hike to the Organ Mountains-Desert Peaks National Monument via an arroyo from the casita, take a dip in the pool, or rest in the peaceful and tastefully decorated space. It is a perfect place for a quiet getaway or as a base to explore the area.

Guest favorite
A charming path leads to the entrance of the guest house, framed by blooming flowers and greenery. Decorative plants line the walkway, while a rustic wooden chair sits invitingly on the porch. The structure features adobe-style architecture under a clear blue sky.
Guesthouse in Las Cruces
4.93 out of 5 average rating, 104 reviews

1 bed cute casita near NMSU, pet friendly

Amazing details throughout this small but mighty space. You have all you need for a quick trip or a longer stay. 1 bedroom with a queen, full-sized kitchen, living room, and dining space as well as a fully fenced, pet-friendly yard. Be immersed in local culture with Talavera tile and Saltillo floors as well as vigas and rough-hewn ceilings and accent walls. The guest house is close to the main house but completely separate and private. Off-street, private parking.

Top guest favorite
A modern interior features a wooden dining table with two black chairs, accompanied by a decorative bowl. A wall hanging adds texture, while a metal rack displays clothing and a woven basket. Natural light filters through a nearby window, highlighting the clean lines of the space.
Guesthouse in Las Cruces
4.99 out of 5 average rating, 202 reviews

Yucca Casita in Historic Mesilla

Mesilla STR Permit #0830 We have created a sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

Top guest favorite
A charming casita features a turquoise door and a light exterior, framed by subtle landscaping. The sky is filled with vibrant orange and yellow hues as the sun sets, creating a striking contrast against the white walls and windows.
Guesthouse in Las Cruces
4.99 out of 5 average rating, 210 reviews

Cozy Casita De Mesilla (Mesilla Cottage)

Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.

Top guest favorite
A living area is furnished with a tan sofa and a vibrant orange chair, complemented by a wooden coffee table. A flat-screen TV is positioned against a wall, while a fan hangs from the ceiling. Arched openings lead to the dining space and kitchen.
Townhouse in Las Cruces
4.99 out of 5 average rating, 244 reviews

Four Hills Casita on the Park

This tranquil home is nestled at the edge of Four Hills Park and features 2 bedrooms and 2 full bathrooms. The updated and upgraded kitchen features a Kuerig, toaster oven, microwave, wine fridge, and stackable washer and dryer. The master bedroom features patio access, a large and luxurious soaking tub, and a step-in shower. The second bedroom features its own patio access. Easy self-check-in w/ coded access lock.

Guest favorite
A warm sleeping area features a queen bed with a neutral quilt and accent pillows. Two bedside lamps illuminate the space with soft light. The ceiling showcases rustic wooden beams, while a framed artwork hangs above the bed, complemented by a textured area rug beneath.
Guesthouse in Las Cruces
4.93 out of 5 average rating, 124 reviews

Rustic Downtown Hideaway

This Rustic guest home has all the amenities, 1 Queen bed, couch sleeps small person or child, and walk-in shower. Inspired by the old west, this guest home has reclaimed wood and tin roof from an old barn in New Mexico. Within walking distance to cafes, restaurants, bars, and shops. Easy private access, keyless entry, and off street parking.

Top guest favorite
The exterior of a single-story casita is shown, featuring a light pink stucco facade and a red-tile roof. A gated entrance is visible, along with a small lawn and a concrete walkway leading to the door. A garage door is also seen on the left.
Guesthouse in Las Cruces
4.95 out of 5 average rating, 1,113 reviews

Cozy Casita with Patio

Cozy casita (guest house) with patio in nice quiet neighborhood close to NMSU, Convention center, Memorial Hospital, Mountain View Hospital, Old Mesilla, ,wine country, shopping, convenient to White Sands, hiking, etc. Casita has private entrance, private bath, small refrigerator, TV, coffee maker, microwave, and wifi

Popular amenities for Doña Ana County vacation rentals