
Vacation rentals in Matlacha Isles-Matlacha Shores
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Matlacha Isles-Matlacha Shores
Guests agree: these stays are highly rated for location, cleanliness, and more.

LAST Minute! NEW Villa-Heated Saltwater Pool & Spa
Experience Cape Coral like never before all from this gorgeous 3bedroom, 3bath villa. This elegant villa boasts a vibrant interior decorated with Italian furniture and fully equipped kitchen. Begin your day with a few laps in the private pool before heading to the Yacht Club Public Beach, Sun Splash Family Waterpark or Pine Island to soak up some sun! After adventurous days, continue making memories back home with a family barbecue and a soak in the hot tub or have a movie night with loved ones!

LUX Villa w/ Private Salt Water Pool, Lanai, Canal
Are you looking to swim, relax outdoors, fish and take in beautiful sunsets on a wide gulf access canal? If so you will fall in love with this stunning newly constructed custom built home! The 2750 square foot home is bright & airy with two main bedroom on-suites & a separate family wing! The gourmet kitchen, dining room & great room open via large sliders to the lanai & pool w/ views of the canal in much desired SW Cape! Beach inspired villa! Large captains walk & Tiki! Check out our reviews!

Key West Style Home w/ Hot Tub & Boat Lift
KEY WEST style stilted waterfront home in the heart of Matlacha! Visit all there is offer - walking distance to Blue Dog and Perfect Cup. Take a boat ride to Cabbage Key, Cayo Costa or Boca Grande! Upstairs and downstairs are screened in. The second floor is peaceful and tranquil overlooking the water and treetops. Home is a 2 bedroom, 2 bathroom, with additional bonus space with trundle bed. Home is perfect for boaters with double driveway, complimentary boat lift and cleaning station.

Sunset POOL Waterfront Kayak bikes fish from dock
New POOL Gulf access waterfront oasis. Downstairs unit 1 bedroom, 1 full bath with bathtub, washer/dryer, kitchen, BBQ grill. Sleeps 6 comfortably. 1 bedroom with pillow top queen bed, memory foam pull out sofa, futon style bed & pack /play crib. In the heart of Matlacha tucked away yet walking distance to town. Bring your boat, use the boat dock, kayak, canoe, bicycles and fishing rods. Jump in the pool after a hot days! Only 9 walking blocks away to restaurants, shops and boat ramp.

Moon Shell Hideaway
Private entrance to your one bedroom plus den (with queen size sleeper/sofa) apartment attached to main house. Direct access to the Gulf of Mexico. Bedroom has a queen size bed and the den has a queen size sleeper/sofa. The den doubles as your kitchenette and sitting area with double sliding glass doors that open up to the shared pool and dock area. Gas grill and microwave for cooking (no stove). Boat to restaurants. Visit the Matlacha Art Galleries. Fish off the dock. WELCOME!

Canal Front Home Heated Pool Private Dock
Escape to this peaceful canal front home in Matlacha Isles, where you can relax in your private heated pool and screened lanai, fish from your private dock, and kayak through scenic waterways. Watch for dolphins and manatees, enjoy beautiful waterfront sunsets, and explore nearby restaurants, shops, and beaches. Comfortable, clean, and thoughtfully equipped, this waterfront retreat is the perfect place to relax, reconnect, and experience the laid back charm of Old Florida.

Boater’s Paradise: No-Bridge Gulf Access & Pool
⚓ Direct Gulf Access (No Bridges): Cruise to open water! 🏊♂️ FREE Heated Pool: Waterfront views, zero daily heating fees. 🛏️ Group Oasis: 4BR | 3BA | 7 Beds (Sleeps 13 comfortably). 🎣 Outdoor Living: Fish from your dock, BBQ & spectacular sunsets! 🐾 Pets Welcome & Fast Wi-Fi! 🚙 Massive Parking: Room for boat trailers! 📍 Location: Heart of Matlacha, minutes to Cape Coral. ⚡ Prime season dates book fast. Lock in your direct water access and reserve your dates today.

2/2 Home in Matlacha!
Check out this 3/3 in the heart of Matlacha! Two bedrooms upstairs with deck overlooking open water and a one-bedroom suite downstairs that includes a kitchenette. Fish right off the deck and catch the freshest fish you will find in SWFL. This property sits on the main road that leads to popular shops and restaurants of Matlacha, including Miceli's, Blue Dog, The Perfect Cup and CW Fudge Factory. Bring your boat! Plenty of space to tie up, minutes to Matlacha Pass.

Modern coastal 3 bedrooms with Pool.
Sun-seekers and casual tourists alike will love staying at this charming Cape Coral home, complete with 3 bedrooms, 3 bathrooms, a thoughtfully appointed interior, and a outdoor electric heated pool! Enjoy the sights and sounds of Cape Coral and lay out on the sands of Yacht Club Public Beach or walk just down the street to Saratoga Lake Park. Let this beautiful vacation rental be your launching point for your coastal adventures.

BRAND NEW Luxury Villa w/Heated and Chilled Pool
Brand new high-end 3 bedroom 3 bath designer home, elegantly decorated with incredible views and direct no-bridge Gulf access. Come and make your lifetime memories in this elegantly appointed executive villa. Located near Matlacha, Sanibel, Fort Myers, and Naples. Extra wide canal with only trees opposite, a salt water lagoon, and just off the spreader canal means incredible solitude and privacy in your elegant oasis retreat.

Pet-Friendly Tropical Oasis
Your tropical oasis awaits! Bring the whole family to this pet-friendly vacation home with lots of room to play and relax on our canal waterfront. You will find all the comforts of home, a heated pool, and many amenities to enhance your stay. Our boat lift is available for use (max 8500 lbs and not a pontoon boat), as well as 2 jet ski docks and a kayak launch. 1 kayak and several fishing poles are also available for use.

Florida, Cape Coral, SunShine
Welcome to your family vacation retreat in beautiful Southwest Florida! This open-concept home is warm and inviting, thoughtfully designed for your comfort, and stocked with everything you need. The clean, cozy, and welcoming space features two king-size beds and two queen-size beds, all with luxurious linens, ensuring everyone has a comfortable place to rest.
Popular amenities for Matlacha Isles-Matlacha Shores vacation rentals
Stay near Matlacha Isles-Matlacha Shores's top sights
Other great vacation rentals in Matlacha Isles-Matlacha Shores

Castaway Sunset Cottage: Waterfront - 100’ Seawall

AquaLux Smart Home

Waterfront/ 2 king beds/ pool/ boat lift

Breathtaking new home with heated pool!

Manatee Haven / with Game Room/Waterfront Retreat!

Waterfront | Speakeasy | Boat Dock

Villa Sunset Serenade II

Waterfront Matlacha views! 2/2 Heated Pool Home
Destinations to explore
- Miami Vacation rentals
- Four Corners Vacation rentals
- Miami Beach Vacation rentals
- Orlando Vacation rentals
- Fort Lauderdale Vacation rentals
- Tampa Vacation rentals
- Hollywood Vacation rentals
- Jacksonville Vacation rentals
- Kissimmee Vacation rentals
- Key West Vacation rentals
- St. Augustine Vacation rentals
- Cape Coral Vacation rentals
- Naples Beach
- Captiva Island
- Turtle Beach
- Caspersen Beach
- Manasota Key Beach
- Englewood Beach
- Lovers Key Beach
- Florida Gulf Coast University
- Myakka River State Park
- Stump Pass Beach State Park
- Bowman's Beach
- Blind Pass Beach
- Barefoot beach Bonita Springs,FL
- Jetblue Park
- North Jetty Beach
- Bonita National Golf & Country Club
- Boca Grande Pass
- The Naples Pier
- South Jetty Beach
- Yacht Club Public Beach
- Edison & Ford Winter Estates
- Ave Maria University
- Bunche Beach
- Coconut Point





