
House vacation rentals in Matlacha
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Top-rated house rentals in Matlacha
Guests agree: these houses are highly rated for location, cleanliness, and more.

McGregor’s Gem• Heated Pool 3BR/2BA River District
🌴 Welcome to McGregor’s Gem—your ideal Southwest Florida retreat! Dive into relaxation in your private heated pool, spread out across three bedrooms and two baths, and enjoy the perfect blend of peaceful tree-lined neighborhood living just minutes from the charming Downtown Fort Myers River District, world-class beaches, and top local attractions.☀️ Whether you’re traveling with family, friends, or on business, this home offers all the modern comforts you need for a relaxing, stress-free stay

The Snook & Rod Club (Waterfront)
Welcome to the Snook & Rod Club. If you want a place to relax, bring your family, or friends this is the place to be! We are on a canal with a 50' captains walk you can tie your vessel to while you stay. Our island getaway property is located on the northern end of Pine Island (off of FT Myers/ Cape Coral) in the quiet community of Bokeelia FL. We are perfectly located in a neighborhood of canals right down from Jug Creek Marina and are set up for retired couples, families, or fishing buddies

Blue Laguna - Vacation in paradise!
This bright, fully equipped welcoming three‑story home features a private heated pool and a rooftop observation deck with stunning 360‑degree water views. It offers three comfortable bedrooms and three full bathrooms for up to six guests, plus two screened lanais where you can relax in the island breeze and listen to the birds. A four‑seater golf cart is included, so you can easily explore the beaches and sandy paths of beautiful North Captiva Island. Also full access to Island Club amenities!

Paradise Pool Waterfront Kayak bike fish from dock
New POOL, waterfront gulf access. Upstairs unit 2 bedrooms 1 full bath kitchen washer/dryer. Sleeps 6 all pillow top beds 1 king 1 queen and 1 queen memory foam pull out pack/ play crib. In the heart of Matlacha walking distance to town. Bring your boat and dock it in the property. Jump in the pool after a hot day, use kayaks, canoe, bikes, fishing rods. Direct TV sports package, high-speed internet. Boat Ramp less than half mile. Guest favorite air conditioning enclosed lanai with table sits

The White Egret On Matlacha
Island home with direct access to Matlacha Pass. A 2-story property equipped with a pool and spa, high-speed internet, smart TV's, and smart home applications. Enjoy the balconies with sunrise and sunset views. Kayak directly off the back dock from the properties private kayak launch . You can fish right off the back dock, bike, or walk to the local shops/restaurants and the world famous Matlacha bridge, which is less than half a mile away. 2 Kayaks and 2 bicycles are included in the rental.

Key West Style Home w/ Hot Tub & Boat Lift
KEY WEST style stilted waterfront home in the heart of Matlacha! Visit all there is offer - walking distance to Blue Dog and Perfect Cup. Take a boat ride to Cabbage Key, Cayo Costa or Boca Grande! Upstairs and downstairs are screened in. The second floor is peaceful and tranquil overlooking the water and treetops. Home is a 2 bedroom, 2 bathroom, with additional bonus space with trundle bed. Home is perfect for boaters with double driveway, complimentary boat lift and cleaning station.

Boater’s Paradise: No-Bridge Gulf Access & Pool
⚓ Direct Gulf Access (No Bridges): Cruise to open water! 🏊♂️ FREE Heated Pool: Waterfront views, zero daily heating fees. 🛏️ Group Oasis: 4BR | 3BA | 7 Beds (Sleeps 13 comfortably). 🎣 Outdoor Living: Fish from your dock, BBQ & spectacular sunsets! 🐾 Pets Welcome & Fast Wi-Fi! 🚙 Massive Parking: Room for boat trailers! 📍 Location: Heart of Matlacha, minutes to Cape Coral. ⚡ Prime season dates book fast. Lock in your direct water access and reserve your dates today.

Pet-Friendly Tropical Oasis
Your tropical oasis awaits! Bring the whole family to this pet-friendly vacation home with lots of room to play and relax on our canal waterfront. You will find all the comforts of home, a heated pool, and many amenities to enhance your stay. Our boat lift is available for use (max 8500 lbs and not a pontoon boat), as well as 2 jet ski docks and a kayak launch. 1 kayak and several fishing poles are also available for use.

Dive into Luxury: Stunning Tropical Home & Pool
Escape to a tropical paradise in this stunning 1952 midcentury modern home, perfectly located in the heart of historical McGregor Boulevard - home to the famous palm trees planted by Thomas Edison. Indulge in delicious meals at local restaurants like McGregor Cafe and McGregor Pizza, or tee off at the nearby public golf course. And if you're looking to hit the beach or explore downtown, both are just a short drive away.

Golden Eye - amazing sunset view. Kayaks included
** NO CONTACT CHECK-IN** Matlacha, it’s a water sports paradise! World class fishing, boating, kayaking, beautiful sunrises and sunsets! See nature come to life and enjoy the tranquility and peacefulness this area offers. Grab your loved ones and get ready to be recharged! Plan a Spring/Summer Vacation getaway! WEEKLY and MONTHLY specials are available

Matlacha Hideaway. Renovated in 2025. Heated pool!
Completely renovated waterfront mid-century modern home with a rare full size and salt water pool in Matlacha. This spacious and stylish home is less than a ten minute walk from the main road with restaurants and shopping. Brand new landscaping, patio, dock and boat lift to help make your time on island memorable.

Matlacha waterfront home
Keep it simple at this peaceful and centrally-located place. Beautiful home features open floor plan, Master suite, Junior master suite. Watch the dolphins and manatees play or take in one of the famous Matlacha sunsets from the dock or screened lanai. Restaurants and shopping close by.
Popular amenities for Matlacha house rentals
House rentals with a pool

Salt Life Serenity

Flirty Flamingo Gulf Access Cape Coral Home

Pine Island paradise, reduced summer price.

Private Paradise on Pine Island

Indulgence - luxury waterfront Heated pool home

Manatee Haven / with Game Room/Waterfront Retreat!

Villa Sunset Serenade II

Waterfront Oasis Private Heated Pool&Canal Fishing
Weekly house rentals

Purple Plum cozy fishing cottage

Florida, Cape Coral, SunShine

Peaceful Lakeview Retreat / Screened Porch & Bikes

The Sweet Escape

Bed and Bay

Island Fun In The Sun! Water on 2 Sides

Paradise on the Water!

Modern City Loft in Downtown River District
Private house rentals

Cozy Cottage on the Farm

Lakeside Sunset / Heated Pool + Sleeps 10

NEW! Beachfront!3BR Suites Sustainable Home+Dock

Waterfront Villa Capri | Dock + Gulf Access

Saltwater Canal Home w/Heated Pool + outdoor tv

Close to Cape Harbour western pool and dock, golf

Charlie's of Bokeelia

Water Front | Modern Open Concept | Beach Vibes
When is the best time to visit Matlacha?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$35,145 GYD | G$39,748 GYD | G$39,539 GYD | G$29,706 GYD | G$26,150 GYD | G$27,614 GYD | G$24,058 GYD | G$22,594 GYD | G$25,104 GYD | G$24,685 GYD | G$27,614 GYD | G$33,263 GYD |
| Avg. temp | 16°C | 18°C | 19°C | 22°C | 25°C | 27°C | 27°C | 28°C | 27°C | 24°C | 21°C | 18°C |
Quick stats about house rentals in Matlacha

Total vacation rentals
Explore 50 vacation rentals in Matlacha

Nightly prices starting at
Matlacha vacation rentals start at G$14,644 GYD per night before taxes and fees

Verified guest reviews
Over 1,230 verified reviews to help you choose

Family-friendly vacation rentals
40 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wi-Fi availability
50 of Matlacha vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Matlacha rentals

4.9 Average rating
Matlacha stays are highly rated by guests—averaging 4.9 out of 5!
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